Cell Biology

Fluorescent micrograph of a multicellular spheroid showing cyan-stained cytoplasmic regions and magenta-stained cell membranes.

The Cell Biology Division investigates the molecular organisation of individual cells and how groups of cells form tissues and organisms.

We aim to provide mechanistic explanations for human physiology and how it is corrupted in disease.

A microscopic image of a placental organoid, with stem cells shown in magenta and more specialised cells in cyan. Learn how 3D stem-cell models are used to study early human development

Major areas of research include protein homeostasis, organelle biology, cytoskeleton and transport, cellular timekeeping, tissue formation, and embryonic development. These fundamental processes are investigated using a combination of light microscopy, mass spectrometry, genetics, biochemistry, electron microscopy and in vitro techniques. The Cell Biology Division’s groups are highly interactive, creating synergy on several shared themes, including cellular homeostasis and tissue formation.

Cell biologists are in an incredibly exciting era in which we can explore how life works from molecules to physiology.

Ramanujan Hegde

JOINT HEAD OF DIVISION

Group Leaders
  • Buzz BaumBuzz BaumCell BiologyThe generation and evolution of biological form: from archaea to eukaryotes
  • Simon BullockSimon BullockCell BiologyMolecular cell biology of cytoskeletal transport
  • Emmanuel DeriveryEmmanuel DeriveryCell BiologyMolecular basis of cell polarisation and asymmetry
  • Juliette FedryJuliette FedryCell BiologyCellular proteostasis networks in physiology and diseases
  • Ramanujan HegdeRamanujan HegdeCell BiologyMembrane protein biosynthesis and quality control
  • Madeline LancasterMadeline LancasterCell BiologyHuman brain development and evolution
  • Roni Levin KonigsbergRoni Levin KonigsbergCell BiologyMolecular physiology of phagocytic cells in health and disease
  • Kate McDoleKate McDoleCell BiologyMorphogenesis of the early mammalian embryo
  • Sean MunroSean MunroCell BiologyOrganisation of the Golgi apparatus
  • John O'NeillJohn O’NeillCell BiologyCellular rhythms, signalling and metabolic regulation
  • Lalita RamakrishnanLalita RamakrishnanMolecular Immunity Unit, Cell BiologyMechanisms of tuberculosis pathogenesis
  • Marta ShahbaziMarta ShahbaziCell BiologyCell fate decisions in the early mammalian embryo
Emeritus
  • Rob KayRob KayCell BiologyHow cells drink and move: macropinocytosis and chemotaxis
  • John KilmartinJohn KilmartinCell BiologyConserved mechanisms of mitosis in yeast and mammals
  • Peter LawrencePeter LawrenceCell BiologyPattern formation in development
  • Hugh PelhamHugh PelhamCell BiologyMembrane protein sorting
  • Andrew TraversAndrew TraversCell BiologyThe mechanics of molecular motors
Fellows
Past Group Leaders Since 2009

Mario de Bono

Moved to the Institute of Science and Technology, Austria, October 2019

Matthew Freeman

Moved to the Sir William Dunn School of Pathology, University of Oxford, December 2012

Christien Merrifield

Moved to CNRS, France, October 2011,  deceased 2017

Liz Miller

Moved to the University of Dundee, July 2025

Ben Nichols

Left the LMB, January 2019

Katja Röper

Moved to the University of Cambridge, March 2024

Melina Schuh

Melina Schuh

Moved to the Max Planck Institute, Göttingen, Germany, December 2015