My interest is the molecular organisation of cellular membranes and how architecture supports membrane-bound functions. In my group at the University of Bern, we aim to directly visualise the organisation of membranes and associated proteins in the cell. To achieve this, we implement and develop correlative light and electron microscopy (CLEM) approaches, including electron cryotomography. At the LMB, we have collaborated intensely towards this goal. With Madeline Lancaster’s group, we combined cryo-CLEM with cerebral organoid technology. We could thereby visualise molecular details in individual developing human axons that we had previously tracked during their growth. Our method allows us to address how growth and structure are related, and ask specific questions on organelles, the cytoskeleton or the cytosolic composition of axons. Our approaches provide insights into cellular organisation at an unprecedented level of detail.