Published Research

Found 204 results for Winter.

• The CCP4 suite: integrative software for macromolecular crystallography AuthorsAgirre J, Atanasova M, Bagdonas H, Ballard CB, Baslé A, Beilsten-Edmands J, Borges RJ, Brown DG, Burgos-Mármol JJ, Berrisford JM, Bond PS, Caballero I, Catapano L, Chojnowski G, Cook AG, Cowtan KD, Croll TI, Debreczeni JÉ, Devenish NE, Dodson EJ, Drevon TR, Emsley P, Evans G, Evans PR, Fando M, Foadi J, Fuentes-Montero L, Garman EF, Gerstel M, Gildea RJ, Hatti K, Hekkelman ML, Heuser P, Hoh SW, Hough MA, Jenkins HT, Jiménez E, Joosten RP, Keegan RM, Keep N, Krissinel EB, Kolenko P, Kovalevskiy O, Lamzin VS, Lawson DM, Lebedev AA, Leslie AGW, Lohkamp B, Long F, Malý M, McCoy AJ, McNicholas SJ, Medina A, Millán C, Murray JW, Murshudov GN, Nicholls RA, Noble MEM, Oeffner R, Pannu NS, Parkhurst JM, Pearce N, Pereira J, Perrakis A, Powell HR, Read RJ, Rigden DJ, Rochira W, Sammito M, Sánchez Rodríguez F, Sheldrick GM, Shelley KL, Simkovic F, Simpkin AJ, Skubak P, Sobolev E, Steiner RA, Stevenson K, Tews I, Thomas JMH, Thorn A, Valls JT, Uski V, Usón I, Vagin A, Velankar S, Vollmar M, Walden H, Waterman D, Wilson KS, Winn MD, Winter G, Wojdyr M, Yamashita K. Journal Acta crystallographica. Section D, Structural Biology 79(Pt 6):449-461 (2023)
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  DOI10.1107/s2059798323003595 PMID37259835 PMCIDPMC10233625 DivisionStructural Studies
• The CCP4 suite: integrative software for macromolecular crystallography AuthorsAgirre J, Atanasova M, Bagdonas H, Ballard CB, Baslé A, Beilsten-Edmands J, Borges RJ, Brown DG, Burgos-Mármol JJ, Berrisford JM, Bond PS, Caballero I, Catapano L, Chojnowski G, Cook AG, Cowtan KD, Croll TI, Debreczeni JÉ, Devenish NE, Dodson EJ, Drevon TR, Emsley P, Evans G, Evans PR, Fando M, Foadi J, Fuentes-Montero L, Garman EF, Gerstel M, Gildea RJ, Hatti K, Hekkelman ML, Heuser P, Hoh SW, Hough MA, Jenkins HT, Jiménez E, Joosten RP, Keegan RM, Keep N, Krissinel EB, Kolenko P, Kovalevskiy O, Lamzin VS, Lawson DM, Lebedev AA, Leslie AGW, Lohkamp B, Long F, Malý M, McCoy AJ, McNicholas SJ, Medina A, Millán C, Murray JW, Murshudov GN, Nicholls RA, Noble MEM, Oeffner R, Pannu NS, Parkhurst JM, Pearce N, Pereira J, Perrakis A, Powell HR, Read RJ, Rigden DJ, Rochira W, Sammito M, Sánchez Rodríguez F, Sheldrick GM, Shelley KL, Simkovic F, Simpkin AJ, Skubak P, Sobolev E, Steiner RA, Stevenson K, Tews I, Thomas JMH, Thorn A, Valls JT, Uski V, Usón I, Vagin A, Velankar S, Vollmar M, Walden H, Waterman D, Wilson KS, Winn MD, Winter G, Wojdyr M, Yamashita K. Journal Acta crystallographica. Section D, Structural Biology 79(Pt 6):449-461 (2023)
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  DOI10.1107/s2059798323003595 PMID37259835 PMCIDPMC10233625 DivisionStructural Studies
• In memoriam: Jefferson Foote AuthorsWard E. S., Jones P., Buss T., Rada C., Winter G., Willson R. Journal Mabs 13(1):1870059. 12 January 2021 (2021)
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  DOI10.1080/19420862.2020.1870059 PMID33435811 PMCIDPMC7808393 DivisionProtein & Nucleic Acid Chemistry
• Circadian VIPergic Neurons of the Suprachiasmatic Nuclei Sculpt the Sleep-Wake Cycle AuthorsCollins B., Pierre-Ferrer S., Muheim C., Lukacsovich D., Cai Y., Spinnler A., Herrera C. G., Wen S., Winterer J., Belle M. D. C., Piggins H. D., Hastings M., Loudon A., Yan J., Földy C., Adamantidis A., Brown S. A. Journal Neuron 108(3):486-499.e5. 11 November 2020 (2020)
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  DOI10.1016/j.neuron.2020.08.001 PMID32916091 PMCIDPMC7803671 DivisionNeurobiology
• Harnessing Evolution to Make Medicines (Nobel Lecture) AuthorsWinter G. Journal Angewandte Chemie 58(41):14438-14445. 7 October 2019 (2019)
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  DOI10.1002/anie.201909343 PMID31529671 PMCID  DivisionProtein & Nucleic Acid Chemistry
• In conversation with Greg Winter AuthorsDhillon P., Winter G. Journal FEBS Journal 286(19):3742-3744. October 2019 (2019)
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  DOI10.1111/febs.15064 PMID31588669 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Sensory-Neuropathy-Causing Mutations in ATL3 Cause Aberrant ER Membrane Tethering AuthorsKrols M., Detry S., Asselbergh B., Almeida-Souza L., Kremer A., Lippens S., De Rycke R., De Winter V., Müller F. J., Kurth I., McMahon H. T., Savvides S. N., Timmerman V., Janssens S. Journal Cell Reports 23(7):2026-2038. 15 May 2018 (2018)
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  DOI10.1016/j. Celrep.2018.04.071 PMID29768202 PMCIDPMC6020997 DivisionNeurobiology
• Background modelling of diffraction data in the presence of ice rings AuthorsParkhurst J. M., Thorn A., Vollmar M., Winter G., Waterman D. G., Fuentes-Montero L., Gildea R. J., Murshudov G. N., Evans G. Journal Iucrj 4(Pt 5):626-638 (2017)
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  DOI10.1107/s2052252517010259 PMID28989718 PMCIDPMC5619854 DivisionStructural Studies
• Robust background modelling in DIALS AuthorsParkhurst J. M., Winter G., Waterman D. G., Fuentes-Montero L., Gildea R. J., Murshudov G. N., Evans G. Journal Journal of Applied Crystallography 49(Pt 6):1912-1921. 1 December 2016 (2016)
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  DOI10.1107/S1600576716013595 PMID27980508 PMCIDPMC5139990 DivisionStructural Studies
• MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA AuthorsGroothuizen F. S., Winkler I., Cristóvão M., Fish A., Winterwerp H. H., Reumer A., Marx A. D., Hermans N., Nicholls R. A., Murshudov G. N., Lebbink J. H., Friedhoff P., Sixma T. K. Journal ELife 4: e06744. 11 July 2015 (2015)
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  DOI10.7554/eLife.06744 PMID26163658 PMCIDPMC4521584 DivisionStructural Studies
• Encoded libraries of chemically modified peptides. AuthorsHeinis C., Winter G. Journal Current Opinion in Chemical Biology 26:89-98. 1 June 2015 (2015)
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  DOI10.1016/j. Cbpa.2015.02.008 PMID25768886 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Subunit disassembly and inhibition of TNFα by a semi-synthetic bicyclic peptide. AuthorsLuzi S., , Bernard E., Stadler L. K., Vaysburd M., Winter G., Holliger P. Journal Protein Engineering, Design & Selection : PEDS 28(2):45-52. 1 February 2015 (2015)
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  DOI10.1093/protein/gzu055 PMID25614525 PMCIDPMC4378371 DivisionProtein & Nucleic Acid Chemistry
• Novel microscale approaches for easy, rapid determination of protein stability in academic and commercial settings AuthorsAlexander C. G., Wanner R., Johnson C. M., Breitsprecher D., Winter G., Duhr S., Baaske P., Ferguson N. Journal Biochimica et Biophysica Acta 1844(12):2241-2250. December 2014 (2014)
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  DOI10.1016/j. Bbapap.2014.09.016 PMID25262836 PMCIDPMC4332417 DivisionProtein & Nucleic Acid Chemistry
• Michael Neuberger (1953‑2013) AuthorsWinter G. Journal European Journal of Immunology 43(12):3090-3091. December 2013 (2013)
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  DOI10.1002/eji.201370126 PMID24414820 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Phage-encoded combinatorial chemical libraries based on bicyclic peptides AuthorsChristian Heinis, Trevor Rutherford, Stephan Freund, Greg Winter Journal Nature Chemical Biology 5(7):502-507 (2009) (2009)
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  DOI10.1038/nchembio.184 PMID19483697 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Repertoires of aggregation-resistant human antibody domains AuthorsChrist D., Famm K., Winter G. Journal Protein Engineering Design and Selection 20(8): 413-416 (2007) (2007)
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  DOI10.1093/protein/gzm037 PMID17720749 PMCID  Division 
• Beta-edge interactions in a pentadecameric human antibody Vk domain AuthorsJames L. C., Jones P. C., McCoy A., Tennent G. A., Pepys M. B., Famm K., Winter G. Journal Journal of Molecular Biology 367(3):603-608. 30 March 2007 (2007)
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  DOI10.1016/j.jmb.2006.10.093 PMID17292396 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Identification of protein domains by shotgun proteolysis AuthorsChrist D., Winter G. Journal Journal of Molecular Biology 358(2):364-371. 28 April 2006 (2006 )
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  DOI10.1016/j.jmb.2006.01.057 PMID16516923 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Inhibition of papillomavirus protein function in cervical cancer cells by intrabody targeting AuthorsGriffin H., Elston R., Jackson D., Ansell K., Coleman M., Winter G., Doorbar J. Journal Journal of Molecular Biology 355(3):360-378. 20 January 2006 (2006 )
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  DOI10.1016/j.jmb.2005.10.077 PMID16324714 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Mapping epitopes and antigenicity by site-directed masking AuthorsDidrik Paus, Greg Winter Journal Proceedings of the National Academy of Sciences, USA 103: 9172-9177 (2006) (2006)
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• Early protein evolution: building domains from ligand-binding polypeptide segments AuthorsLutz Riechmann, Greg Winter Journal J. Mol. Biol. 363: 460-468 (2006) (2006)
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• Engineering aggregation-resistant proteins by directed evolution AuthorsK. Famm, G. Winter Journal Protein Engineering, Design & Selection 19: 479-481 (2006) (2006)
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• Tapping diversity lost in transformations - in vitro amplification of ligation reactions AuthorsDaniel Christ, Kristoffer Famm, Greg Winter Journal Nucleic Acids Research 34: e108 (2006) (2006)
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• Generating molecular diversity by homologous recombination in Escherichia coli AuthorsWang P. L., Lo B. K. C., Winter G. Journal Protein Engineering, Design & Selection 18(8):397-404. August 2005 (2005)
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  DOI10.1093/protein/gzi042 PMID15983006 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Folding and stability of a primitive protein AuthorsRiechmann L., Lavenir I., de Bono S., Winter G. Journal Journal of Molecular Biology 348(5):1261-1272. 20 May 2005 (2005)
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  DOI10.1016/j.jmb.2005.03.029 PMID15854659 PMCID  DivisionProtein & Nucleic Acid Chemistry
• A segment of cold shock protein directs the folding of a combinatorial protein AuthorsStephanie de Bono, Lutz Riechmann, Eric Girard, Roger L. Williams, Greg Winter Journal Proceedings of the National Academy of Sciences, USA 102: 1396-1401 (2005) (2005)
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• The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J AuthorsMarieke Levitus, Quinten Waisfisz, Barbara C. Godthelp, Yne de Vries, Shobbir Hussain, Wouter W. Wiegant, Elhaam Elghalbzouri-Maghrani, Jurgen Steltenpool, Martin A. Rooimans, Gerard Pals, Fre Arwert, Christopher G. Mathew, Malgorzata Z. Zdzienicka, Kevin Hiom, Johan P. De Winter, Hans Joenje Journal Nature Genetics 37: 934-935 (2005) (2005)
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• Selection of optical biosensors from chemisynthetic antibody libraries AuthorsJespers L., Bonnert T. P., Winter G. Journal Protein Engineering, Design & Selection 17(10):709-713. October 2004 (2004)
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  DOI10.1093/protein/gzh083 PMID15537669 PMCID  DivisionProtein & Nucleic Acid Chemistry
• The Fanconi anemia gene product FANCF is a flexible adaptor protein AuthorsLeveille F., Blom E., Medhurst A. L.., Bier P., Laghmani el H., Johnson M., Rooimans M. A., Sobeck A., Waisfisz Q., Arwert F., Patel K. J., Hoatlin M. E., Joenje H., de Winter J. P. Journal Journal of Biological Chemistry 279(38):39421-39430. 17 September 2004 (2004)
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  DOI10.1074/jbc.m407034200 PMID15262960 PMCID  DivisionProtein & Nucleic Acid Chemistry
• A native-like artificial protein from antisense DNA AuthorsNicolas Fischer, Lutz Riechmann, Greg Winter Journal Protein Engineering, Design & Selection 17: 13-20 (2004) (2004)
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• Crystal structure of HEL4, a soluble, refoldable human VH single domain with a germ-line scaffold AuthorsLaurent Jespers, Oliver Schon, Leo C. James, Dmitri Veprintsev, Greg Winter Journal Journal of Molecular Biology 337: 893-903 (2004) (2004)
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• Aggregation-resistant domain antibodies selected on phage by heat denaturation AuthorsLaurent Jespers, Oliver Schon, Kristoffer Famm, Greg Winter Journal Nature Biotechnology 22: 1161-1165 (2004) (2004)
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• Hyperimmunoglobulinemia and rate of HIV type 1 infection progression AuthorsArthur Abelian, Keith Burling, Philippa Easterbrook, Greg Winter Journal AIDS Research and Human Retroviruses 20: 127-128 (2004) (2004)
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• Stabilization of antibody VH-domains by proteolytic selection AuthorsHiroshi Ueda, Peter Kristensen, Greg Winter Journal Journal of Molecular Catalysis B: Enzymatic 28: 173-179 (2004) (2004)
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• Identification of functional similarities between proteins using directed evolution AuthorsDaniel Christ, Greg Winter Journal Proceedings of the National Academy of Sciences, USA 100: 13202-13206 (2003) (2003)
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• Automation of the collection and processing of X-ray diffraction data - a generic approach AuthorsLeslie A. G. W., Powell H. R., Winter G., Svensson O., Spruce D.,McSweeney S., Love D., Kinder S., Duke E., Nave C. Journal Acta Crystallographica Section D: Biological Crystallography D58(Pt 11):1924-1928 (2002) (2002)
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  DOI10.1107/s0907444902016864 PMID12393923 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Selection of large diversities of antiidiotypic antibody fragments by phage display AuthorsSteffen Goletz, Peter Astrup Christensen, Peter Kristensen, Dietmar Blohm, Ian Tomlinson, Greg Winter, Uwe Karsten Journal Journal of Molecular Biology 315: 1087-1097 (2002) (2002)
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• Single-chain antibody-based gene therapy: inhibition of tumor growth by in situ production of phage-derived human antibody fragments blocking functionally active sites of cell-associated matrices AuthorsL. Sanz, P. Kristensen, B. Blanco, S. Facteau, S. J. Russell, G. Winter, L. Alvarez‑Vallina Journal Gene Therapy 9: 1049-1053 (2002) (2002)
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• Improving the display of proteins on filamentous phage AuthorsJean-Luc Jestin, Georgia Volioti, Greg Winter Journal Res. Microbiol. 152: 187-191 (2001) (2001)
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• Molecular characterization of human monoclonal antibodies derived from fusions of tonsil lymphocytes with a human myeloma cell line AuthorsMarina Vaisbourd, Olga Ignatovich, Alla Dremucheva, Abraham Karpas, Greg Winter Journal Hybridoma and Hybridomics 20: 287-292 (2001) (2001)
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• The 'wildtype' conformation of p53: epitope mapping using hybid proteins AuthorsPeter L. Wang, Fiona Sait, Greg Winter Journal Oncogene 20: 2318-2324 (2001) (2001)
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• Novel folded protein domains generated by combinatorial shuffling of polypeptide segments AuthorsRiechmann L., Winter G. Journal Proceedings of the National Academy of Sciences, USA 97(18):10068-10073. 29 August 2000 (2000)
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  DOI10.1073/pnas.170145497 PMID10954734 PMCIDPMC27691 DivisionProtein & Nucleic Acid Chemistry
• Comparable heavy and light chain pairings in normal and systemic lupus erythematosus IgG+ B cells AuthorsRuud M. T. de Wildt, Ian M. Tomlinson, Walther J. van Venrooij, Greg Winter, Rene M. A. Hoet Journal Eur. J. Immunol. 30: 354-261 (2000) (2000)
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• Cell-growth control by monomeric antigen: the cell surface expression of lysozyme-specific Ig V-domains fused to truncated Epo receptor AuthorsHiroshi Ueda, Masahiro Kawahara, Takahide Aburatani, Kouhei Tsumoto, Kazuo Todokoro, Eiji Suzuki, Hajime Nishimura, Paula A. Schueler, Greg Winter, Walt C. Mahoney, Izumi Kumagai, Teruyuki Nagamune Journal Journal of Immunological Methods 241: 159-170 (2000) (2000)
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• Interdomain interactions within the gene 3 protein of filamentous phage AuthorsJean Chatellier, Oliver Hartley, Andrew D. Griffiths, Alan R. Fersht, Greg Winter, Lutz Riechmann Journal FEBS Letters 463: 371-374 (1999) (1999)
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• Somatic insertions and deletions shape the human antibody repertoire AuthorsRuud M. T. de Wildt, Walther J. van Venrooij, Greg Winter, Rene M. A. Hoet, Ian M. Tomlinson Journal Journal of Molecular Biology 294: 701-710 (1999) (1999)
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• Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire AuthorsRuud M. T. de Wildt, Rene M. A. Hoet, Walther J. van Venrooij, Ian M. Tomlinson, Greg Winter Journal Journal of Molecular Biology 285: 895-901 (1999) (1999)
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• Dominance of intrinsic genetic factors in shaping the human immunoglobulin Vgamma repertoire AuthorsOlga Ignatovich, Ian M. Tomlinson, Andrei V. Popov, Marianne Bruggemann, Greg Winter Journal Journal of Molecular Biology 294: 457-465 (1999) (1999)
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• Towards the design of an antibody that recognises a given protein epitope AuthorsPerry M. Kirkham, Dario Neri, Greg Winter Journal Journal of Molecular Biology 285: 909-915 (1999) (1999)
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• A method for the selection of catalytic activity using phage display and proximity coupling AuthorsJean-Luc Jestin, Peter Kristensen, Greg Winter Journal Angew. Chem. Int. Ed. 38: 1124-1127 (1999) (1999)
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• A strategy for the isolation of catalytic activities from repertoires of enzymes displayed on phage AuthorsSalvatore Demartis, Adrian Huber, Francesca Viti, Luisa Lozzi, Leonardo Giovannoni, Paolo Neri, Greg Winter, Dario Neri Journal Journal of Molecular Biology 286: 617-633 (1999) (1999)
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• Identification of a glioblastoma-associated Tenascin-C isoform by a high affinity recombinant antibody AuthorsBarbara Carnemolla, Patrizia Castellani, Marco Ponassi, Laura Borsi, Stefania Urbini, Guido Nicolo, Alessandra Dorcaratto, Giuseppe Viale, Greg Winter, Dario Neri, Luciano Zardi Journal American Journal of Pathology 154:1345–1352 (1999) (1999)
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• Carcinoembryonic antigen (CEA)-specific T-cell activation in colon carcinoma induced by anti-CD3xAnti-CEA bispecific diabodies and B7xAnti-CEA bispecific fusion proteins AuthorsPhilipp Holliger, Oliver Manzke, Mary Span, Robert Hawkins, Bernd Fleischmann, Liu Qinghua, Jurgen Wolf, Volker Diehl, Olivier Cochet, Greg Winter, Heribert Bohlen Journal Cancer Reseach 59: 2909-2916 (1999) (1999)
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• Making antibody and peptide ligands by repertoire selection technologies AuthorsWinter G. Journal Journal of Molecular Recognition 11(1-6):126-127. December 1998 (1998)
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  DOI10.1002/(sici)1099-1352(199812)11:1/6<126::aid-jmr407>3.0. Co;2-h PMID10076824 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Synthetic human antibodies and a strategy for protein engineering AuthorsWinter G. Journal FEBS Letters 430(1-2):92-94. 23 June 1998 (1998)
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  DOI10.1016/s0014-5793(98)00628-0 PMID9678601 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Small binding proteins selected from a combinatorial repertoire of knottins displayed on phage AuthorsSmith G. P., Patel S. U., Windass J. D., Thornton J. M., Winter G., Griffiths A. D. Journal Journal of Molecular Biology 277(2):317-332. 27 March 1998 (1998)
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  DOI10.1006/jmbi.1997.1621 PMID9514763 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Recombinant human single chain Fv antibodies recognizing human interleukin-6. Specific targeting of cytokine-secreting cells AuthorsBarbara Krebs, Heather Griffin, Greg Winter, Stefan Rose‑John Journal Journal of Biological Chemistry 273: 2858-2865 (1998) (1998)
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• Proteolytic selection for protein folding using filamentous bacteriophages AuthorsPeter Kristensen, Greg Winter Journal Folding and Design 3: 321-328 (1998) (1998)
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• Expression of an antibody fragment at high levels in the bacterial cytoplasm AuthorsPierre Martineau, Peter Jones, Greg Winter Journal Journal of Molecular Biology 280: 117-127 (1998) (1998)
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• Panning phage antibody libraries on cells: isolation of human Fab fragments against ovarian carcinoma using guided selection AuthorsMariangela Figini, Laura Obici, Delia Mezzanzanica, Andrew Griffiths, Maria I. Colnaghi, Greg Winter, Silvana Canevari Journal Cancer Research 58 : 991 - 996 (1998) (1998 )
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• Diabodies : small bispecific antibody fragments AuthorsHolliger P., Winter G. Journal Cancer Immunology and Immunotherapy 45(3-4):128-130. Nov-Dec 1997 (1997)
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  DOI10.1007/s002620050414 PMID9435855 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Improved tumour targeting by disulphide stabilized diabodies expressed in Pichia pastoris AuthorsFitzGerald K., Holliger P., Winter G. Journal Protein Engineering 10(10):1221-1225. October 1997 (1997)
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  DOI10.1093/protein/10.10.1221 PMID9488147 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Retargeting serum immunoglobulin with bispecific diabodies AuthorsHolliger P., Wing M., Pound J. D., Bohlen H., Winter G. Journal Nature Biotechnology 15(7):632-636. July 1997 (1997)
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  DOI10.1038/nbt0797‑632 PMID9219264 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Complement recruitment using bispecific diabodies AuthorsKontermann R. E., Wing M. G., Winter G. Journal Nature Biotechnology 15(7):629-631. July 1997 (1997 )
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  DOI10.1038/nbt0797‑629 PMID9219263 PMCID  DivisionProtein & Nucleic Acid Chemistry
• The creation of diversity in the human immunoglobulin Vgamma repertoire AuthorsIgnatovich O., Tomlinson I. M., Jones P. T., Winter G. Journal Journal of Molecular Biology 268(1):69-77. 25 April 1997 (1997)
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  DOI10.1006/jmbi.1997.0956 PMID9149142 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Dimerization of Fab fragments enables ready screening of phage antibodies that affect hepatocyte growth factor/scatter factor activity on target cells AuthorsZaccolo M., Griffiths A. P., Prospero T. D., Winter G., Gherardi E. Journal European Journal of Immunology 27(3):618-623. March 1997 (1997 )
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  DOI10.1002/eji.1830270307 PMID9079800 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo AuthorsGuido Hartmann, Terence Prospero, Volker Brinkman, Oemil Ozcelik, Greg Winter, Jonathan Hepple, Sarah Batley, Friedhelm Bladt, Martin Sachs, Carmen Birchmeier, Walter Birchmeier, Ermanno Gherardi Journal Current Biology 8: 125-134 (1997) (1997)
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• Characterization of events during the late stages of HPV16 infection in Vivo using high-affinity synthetic Fabs to E4 AuthorsJohn Doorbar, Charmaine Foo, Nick Coleman, Liz Medcalf, Oliver Hartley, Terence Prospero, Sawsan Napthine, Jane Sterling, Greg Winter, Heather Griffin Journal Virology 238: 40-52 (1997) (1997)
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• Enzyme immunoassays using bispecific diabodies AuthorsRoland E. Kontermann, Pierre Martineau, Corinne E. Cummings, Abraham Karpas, Deborah Allen, Elaine Derbyshire, Greg Winter Journal Immunotechnology 3: 137-144 (1997) (1997)
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• Immunoglobulin lambda light chain orphons on human chromosome 8q11.2 AuthorsJean-Pol Frippiat, Patricia Dard, Sharon Marsh, Greg Winter, Marie-Paule Lefranc Journal European Journal of Immunology 27 : 1260-1265 (1997) (1997 )
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• Targeting by affinity-matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform AuthorsDario Neri, Barbara Carnemolla, Ahuva Nissim, Alessandra Leprini, Germano Querze, Enrica Balza, Alessandro Pini, Lorenzo Tarli, Cornelia Halin, Paolo Neri, Luciano Zardi, Greg Winter Journal Nature Biotechnology 15 : 1271-1275 (1997) (1997)
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• Open sandwich ELISA : a novel immunoassay based on the interchain interaction of antibody variable region AuthorsUeda H., Tsumoto K., Kubota K., Suzuki E., Nagamune T., Nishimura H., Paula A. Schueler, Winter G., Kumagai I., Mahoney W. C. Journal Nature Biotechnology 14(13):1714-1718. December 1996 (1996 )
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  DOI10.1038/nbt1296‑1714 PMID9634858 PMCID  DivisionProtein & Nucleic Acid Chemistry
• The imprint of somatic hypermutation on the repertoire of human germline V genes AuthorsIan M. Tomlinson, Gerald Walter, Peter T. Jones, Paul H. Dear, Erik L. L. Sonnhammer, Greg Winter Journal Journal of Molecular Biology 256: 813-817 (1996) (1996)
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• Phage antibodies against an unstable hapten: oxygen sensitive reduced flavin AuthorsYvonne E. Bruggeman, Anja Boogert, Arie van Hoek, Peter T. Jones, Greg Winter, Arjen Schots, Riet Hilhorst Journal FEBS Letters 388: 242-244 (1996) (1996)
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• A strategy of exon shuffling for making large peptide repertoires displayed on filamentous bacteriophage AuthorsIgor Fisch, Roland E. Kontermann, Ricarda Finnern, Oliver Hartley, Andres S. Soler-Gonzalez, Andrew D. Griffiths, Greg Winter Journal Proceedings of the National Academy of Sciences, USA 93: 7761-7766 (1996) (1996)
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• Mimicking somatic hypermutation: affinity maturation of antibodies displayed on bacteriophage using a bacterial mutator strain AuthorsNigel M. Low, Philipp Holliger, Greg Winter Journal Journal of Molecular Biology 260: 359-368 (1996) (1996)
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• Sequence and evolution of the human germline V lambda repertoire AuthorsSamuel C. Williams, Jean-Pol Frippiat, Ian M. Tomlinson, Olga Ignatovich, Marie-Paule Lefranc, Greg Winter Journal Journal of Molecular Biology 264: 220-232 (1996) (1996)
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• Screening of phage antibody libraries AuthorsJacqueline L. Harrison, Samuel C. Williams, Greg Winter, Ahuva Nissim Journal Methods in Enzymology 267 : 83-109 (1996) (1996)
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• Specific killing of lymphoma cells by cytoxic T-cells mediated by a bispecific diabody AuthorsPhilipp Holliger, Jan Brissinck, Roger L. Williams, Kris Thielemans, Greg Winter Journal Protein Engineering 9 : 299-305 (1996) (1996)
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• Radioactive labeling of recombinant antibody fragments by phosphorylation using human casein kinase II and [(gamma)-32P]-ATP AuthorsDario Neri, Heike Petrul, Greg Winter, Yvonne Light, Richard Marais, Keith E. Britton, Andrew M. Creighton Journal Nature Biotechnology 14 : 485-490 (1996) (1996 )
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• Multipurpose high sensitivity luminescence analyzer (LUANA) : use in gel electrophoresis AuthorsNeri D., Prospero T., Petrul H., Winter G., Browne M., Vanderpant L. Journal BioTechniques 20(4):708-713 (1996 )
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• A complete map of the human immunoglobulin VH locus AuthorsIan M. Tomlinson, Graham P. Cook, Gerald Walter, Nigel P. Carter, Harold Riethman, Lakjaya Buluwela, Terence H. Rabbitts, Greg Winter Journal Annals of the New York Academy of Sciences 764 : 43-46. September 1995 (1995 )
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  DOI10.1111/j.1749-6632.1995.tb55804.x PMID7486559 PMCID  Division 
• An antibody fragment from a phage display library competes for ligand binding to the low density lipoprotein receptor family and inhibits rhinovirus infection AuthorsRegina A. Hodits, Johannes Nimpf, Doris M. Pfistermueller, Thomas Hiesberger, Wolfgang J. Schneider, Tristan J. Vaughan, Kevin S. Johnson, Markus Haumer, Ernst Kuechler, Greg Winter, Dieter Blaas Journal Journal of Biological Chemistry 270: 24078-24085 (1995) (1995)
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• High-affinity antigen binding by chelating recombinant antibodies (CRAbs) AuthorsDario Neri, Monica Momo, Terence Prospero, Greg Winter Journal Journal of Molecular Biology 246: 367-373 (1995) (1995)
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• Comparison of the human germline and rearranged VH repertoire reveals complementarity between germline variability and somatic mutation AuthorsGerald Walter, Ian M. Tomlinson, Paul H. Dear, Erik, L. L. Sonnhammer, Graham P. Cook, Greg Winter Journal Annals of the New York Academy of Sciences 764 : 180 - 182 (1995) (1995)
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• Organization of the human immunoglobulin lambda light-chain locus on chromosome 22q11.2 AuthorsJean-Pol Frippiat, Samuel C. Williams, Ian M. Tomlinson, Graham P. Cook, Dorra Cherif, Denis Le Paslier, John E. Collins, Ian Dunham, Greg Winter, Marie-Paule Lefranc Journal Human Molecular Genetics 4 : 983-991 (1995) (1995)
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• Idiotypic vaccination against human B-cell lymphoma. Rescue of variable region gene sequences from biopsy material for assembly as single-chain Fv personal vaccines AuthorsHawkins R. E., Zhu D., Ovecka M., Winter G., Hamblin T. J., Long A., Stevenson F. K. Journal Blood 83(11):3279-88. 1 June 1994 (1994)
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• A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q AuthorsGraham P. Cook, Ian M. Tomlinson, Gerald Walter, Harold Riethman, Nigel P. Carter, Lakjaya Buluwela, Greg Winter, Terence H. Rabbitts Journal Nature Genetics 7: 162-168 (1994) (1994)
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• Crystal structure of a diabody, a bivalent antibody fragment AuthorsOlga Perisic, Philip A. Webb, Philipp Holliger, Greg Winter, Roger L. Williams Journal Structure 2: 1217-1226 (1994) (1994)
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• Making antibodies by phage display technology AuthorsGreg Winter, Andrew D. Griffiths, Robert E. Hawkins, Hennie R. Hoogenboom Journal Annu. Rev. Immunol. 12: 433-455 (1994) (1994)
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• A directory of human germ-line V [kappa] segments reveals a strong bias in their usage AuthorsJonathan P. L. Cox, Ian M. Tomlinson, Greg Winter Journal European Journal of Immunology 24 : 827-836 (1994) (1994)
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• Isolation of high affinity human antibodies directly from large synthetic repertoires AuthorsAndrew D. Griffiths, Samuel C. Williams, Oliver Hartley, Peter Waterhouse, William L. Crosby, Roland E. Kontermann, Peter T. Jones, Nigel M. Low, T. John Allison, Terence D. Prospero, Hennie R. Hoogenboom, Ahuva Nissim, Jonathan P. L. Cox, Jacqueline L. Harrison, Manuela Zaccolo, Ermanno Gherardi, Greg Winter Journal EMBO Journal 13 : 3245-3260 (1994 )
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• Antibody fragments from a "single pot" phage display library as immunochemical reagents AuthorsAhuva Nissim, Hennie R. Hoogenboom, Ian M. Tomlinson, Greg Flynn, Carol Midgley, David Lane, Greg Winter Journal EMBO Journal 13 : 692-698 (1994) (1994)
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• Human immunoglobulin VH and D segments on chromosomes 15q11.2 and 16p11.2 AuthorsIan M. Tomlinson, Graham P. Cook, Nigel P. Carter, Ramnath Elaswarapu, Sarah Smith, Gerald Walter, Lakjaya Buluwela, Terence H. Rabbitts, Greg Winter Journal Human Molecular Genetics 3 : 853-860 (1994)
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• In vitro assembly of repertoires of antibody chains on the surface of phage by renaturation AuthorsMariangela Figini, James D. Marks, Greg Winter, Andrew Griffiths Journal Journal of Molecular Biology 239 : 68 - 78 (1994) (1994)
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• Guiding the selection of human antibodies from phage display repertoires to a single epitope of an antigen AuthorsLaurent S. Jespers, Andy Roberts, Stephen M. Mahler, Greg Winter, Hennie R. Hoogenboom Journal Bio/Technology 12: 899-903 (1994) (1994)
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• Phage libraries for generation of clinically useful antibodies AuthorsKerry A. Chester, Richard H. J. Begent, Lynda Robson, Patricia Keep, R. Barbara Pedley, Joan A. Boden, Geoff Boxer, Alan Green, Greg Winter, Olivier Cochet, Robert E. Hawkins Journal Lancet 343: 455-456 (1994) (1994)
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• HAPPY mapping of a YAC reveals alternative haplotypes in the human immunoglobulin VH locus AuthorsGerald Walter, Ian M. Tomlinson, Graham P. Cook, Greg Winter, Terry H. Rabbitts, Paul H. Dear Journal Nucleic Acids Research 21: 4524-4529 (1993) (1993)
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• Humanized antibodies AuthorsWinter G., Harris W. J. Journal Immunology Today 14: 243-246 (1993) (1993)
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• "Diabodies": small bivalent and bispecific antibody fragments AuthorsPhilipp Holliger, Terence Prospero, Greg Winter Journal Proceedings of the National Academy of Sciences, USA 90: 6444-6448 (1993) (1993)
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• Retroviral vectors displaying functional antibody fragments AuthorsStephen J. Russell, Robert E. Hawkins, Greg Winter Journal Nucleic Acids Research 21: 1081-1085 (1993) (1993)
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• Combinatorial infection and in vivo recombination: a strategy for making large phage antibody repertoires AuthorsPeter Waterhouse, Andrew D. Griffiths, Kevin S. Johnson, Greg Winter Journal Nucleic Acids Research 21: 2265-2266 (1993) (1993)
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• Human anti-self antibodies with high specificity from phage display libraries AuthorsAndrew D. Griffiths, Magnus Malmqvist, James D. Marks, Jacqueline M. Bye, M. J. Embleton, John McCafferty, Michael Baier, K. Philipp Holliger, Barbara D. Gorick, Nevin C. Hughes-Jones, Hennie R. Hoogenboom, Greg Winter Journal EMBO Journal 12: 725-734 (1993) (1993)
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• The contribution of contact and non-contact residues of antibody in the affinity of binding to antigen. The interaction of mutant D1.3 antibodies with lysozyme AuthorsRobert E. Hawkins, Stephen J. Russell, Michael Baier, Greg Winter Journal Journal of Molecular Biology 234: 958-964 (1993) (1993)
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• A genetic approach to idiotypic vaccination AuthorsRobert E. Hawkins, Greg Winter, Terry J. Hamblin, Freda K. Stevenson, Stephen J. Russell Journal Journal of Immunotherapy 14: 273-278 (1993) (1993)
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• Engineering bispecific antibodies AuthorsPhilipp Holliger, Greg Winter Journal Current Opinion in Biotechnology 4: 446-449 (1993) (1993)
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• Human antibody fragments specific for human blood group antigens from a phage display library AuthorsJames D. Marks, Willem H. Ouwehand, Jacqueline M. Bye, Ricarda Finnern, Barbara D. Gorick, Douglas Voak, Susan J. Thorpe, Nevin C. Hughes-Jones, Greg Winter Journal Bio/Technology 11: 1145-1149 (1993) (1993)
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• Cloning and sequencing of human immunoglogulin Vgamma gene segments AuthorsSamuel C. Williams, Greg Winter Journal Eur. J. Immunol 23: 1456-1461 (1993) (1993)
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• Humanized antibodies AuthorsGreg Winter, William J. Harris Journal TiPS 14: 139-143 (1993) (1993)
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• Immunological technqiues (Editorial overview) AuthorsGreg Winter Journal Current Opinion in Immunology 5: 253-255 (1993) (1993)
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• Antibody engineering AuthorsG. Winter, S. Ward Journal Clinical Aspects of Immunology. 5th edition pp.817-828 (1993) (1993)
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• Structural repertoire of the human VH segments AuthorsChothia C., Lesk A. M., Gherardi E., Tomlinson I. M., Walter G., Marks J. D., Llewelyn M. B., Winter G. Journal Journal of Molecular Biology 227(3):799-817 (1992) (1992)
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  DOI10.1016/0022-2836(92)90224-8 PMID1404389 PMCID  Division 
• Cell selection strategies for making antibodies from variable gene libraries: trapping the memory pool AuthorsRobert E. Hawkins, Greg Winter Journal Eur. J. Immunol. 22: 867-870 (1992) (1992)
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• Recombinant mouse monoclonal antibodies with single amino acid substitutions affecting C1q and high affinity Fc receptor binding have identical serum half-lives in the BALB/c mouse AuthorsEdward J. Wawrzynczak, Sylvia Denham, Geoffrey D. Parnell, Alan J. Cumber, Peter T. Jones, Greg WInter Journal Molecular Immunology 29: 221-227 (1992) (1992)
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• In-cell PCR from mRNA: amplifying and linking the rearranged immunoglobulin heavy and light chain V-genes within single cells AuthorsM. J. Embleton, Guy Gorochov, Peter T. Jones, Greg Winter Journal Nucleic Acids Research 20: 3831-3837 (1992) (1992)
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• Selection of phage antibodies by binding affinity. Mimicking affinity maturation AuthorsRobert E. Hawkins, Stephen J. Russell, Greg Winter Journal Journal of Molecular Biology 226: 889-896 (1992) (1992)
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• Molecular evolution of proteins on filamentous phage. Mimicking the strategy of the immune system AuthorsJames D. Marks, Hennie R. Hoogenboom, Andrew D. Griffiths, Greg Winter Journal Journal of Biological Chemistry 267: 16007-16010 (1992) (1992)
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• Germline variable region gene segment derivation of human monoclonal anti-Rh (D) antibodies AuthorsJacqueline M. Bye, Christine Carter, Yungchang Cui, Barbara D. Gorick, Sirirurg Songsivilai, Greg Winter, Nevin C. Hughes-Jones, James D. Marks Journal J. Clin. Invest. 90: 2481-2490 (1992) (1992)
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• Comparative stabilities in vitro and in vivo of a recombinant mouse antibody FvCys fragment and a bisFvCys conjugate AuthorsAlan J. Cumber, E. Sally Ward, Greg Winter, Geoffrey D. Parnell, Edward J. Wawrzynczak Journal Journal of Immunology 149: 120-126 (1992) (1992)
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• Protein engineering AuthorsAlan Fersht, Greg Winter Journal Trends in Biochemical Sciences 17: 293-294 (1992) (1992)
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• Antibody framework residues affecting the conformation of the hypervariable loops AuthorsJefferson Foote, Greg Winter Journal Journal of Molecular Biology 224: 487-499 (1992) (1992)
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• Building antibodies from their genes AuthorsHennie R. Hoogenboom, James D. Marks, Andrew D. Griffiths, Greg Winter Journal Immunological Reviews 130: 41-68 (1992) (1992)
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• By-passing immunisation. Human antibodies fron synthetic repertoires of germline VH gene segments rearranged in vitro AuthorsHennie R. Hoogenboom, Greg Winter Journal Journal of Molecular Biology 227: 381-388 (1992) (1992)
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• Multiple binding sites on the CH2 domain of IgG for mouse FcgammaR11 AuthorsJohn Lund, John D. Pound, Peter T. Jones, Alexander R. Duncan, Tracy Bentley, Margaret Goodall, Barry A. Levine, Royston Jefferis, Greg Winter Journal Molecular Immunology 29: 53-59 (1992) (1992)
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• By-passing immunization: building high affinity human antibodies by chain shuffling AuthorsJames D. Marks, Andrew D. Griffiths, Magnus Malmqvist, Tim P. Clackson, Jacqueline M. Bye, Greg Winter Journal Bio/Technology 10: 779-783 (1992) (1992)
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• An artificial immune system for making antibodies AuthorsJ. D. Marks, G. Winter Journal Behring Inst. Mitt. 91: 6-12 (1992) (1992)
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• The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops AuthorsIan M. Tomlinson, Gerald Walter, James D. Marks, Meirion B. Llewelyn, Greg Winter Journal Journal of Molecular Biology 227: 776-798 (1992) (1992)
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• Blood clearance in the rat of a recombinant mouse monoclonal antibody lacking the N-linked oligosaccharide side chains of the CH2 domains AuthorsEdward J. Wawrzynczak, Alan J. Cumber, Geoffrey D. Parnell, Peter T. Jones, Greg Winter Journal Molecular Immunology 29: 213-220 (1992) (1992)
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• Filter screening of antibody Fab fragments secreted from individual bacterial colonies: specific detection of antigen binding with a two-membrane system AuthorsArne Skerra, Martin L. Dreher, Greg Winter Journal Analytical Biochemistry 196: 151-155 (1991) (1991)
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  DOI10.1016/0003-2697(91)90131-C PMID1888028 PMCID  Division 
• Man-made antibodies AuthorsWinter G., Milstein C. Journal Nature 349(6307):293-299. 24 January 1991 (1991)
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  DOI10.1038/349293a0 PMID1987490 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Human FcGammaRI and FcGammaRII interact with distinct but overlapping sites on human IgC1 AuthorsJohn Lund, Greg Winter, Peter T. Jones, John D. Pound, Toshiyuki Tanaka, Matthew R. Walker, Peter J. Artymiuk, Yogi Arata, Dennis R. Burton, Royston Jefferis, Jennifer M. Woof Journal Journal of Immunology 147: 2657-2662 (1991 ) (1991)
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• Making antibody fragments using phage display libraries AuthorsTim Clackson, Hennie R. Hoogenboom, Andrew D. Griffiths, Greg Winter Journal Nature 352: 624-628 (1991 ) (1991)
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• Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains AuthorsHennie R. Hoogenboom, Andrew D. Griffiths, Kevin S. Johnson, David J. Chiswell, Peter Hudson, Greg Winter Journal Nucleic Acids Research 19: 4133-4137 (1991) (1991)
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• By-passing immunization. Human antibodies from V-gene libraries displayed on phage AuthorsJames D. Marks, Hennie R. Hoogenboom, Timothy P. Bonnert, John McCafferty, Andrew D. Griffiths, Greg Winter Journal Journal of Molecular Biology 222: 581-597 (1991) (1991)
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• Oligonucleotide primers for polymerase chain reaction amplification of human immunoglobulin variable genes and design of family-specific oligonucleotide probes AuthorsJames D. Marks, Michael Tristem, Abraham Karpas, Greg Winter Journal Eur. J. Immunol 21: 985-991 (1991) (1991)
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• Crystallization and preliminary X-ray diffraction study of the bacterially expressed Fv from the monoclonal anti-lysozyme antibody D1.3 and of its complex with the antigen, lysozyme AuthorsGinette Boulot, Jean-Luc Eisele, Graham A. Bentley, T. Narayana Bhat, E. Sally Ward, Greg Winter, Roberto J. Poljak Journal Journal of Molecular Biology 213: 617-619 (1990) (1990)
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• Phage antibodies: filamentous phage displaying antibody variable domains AuthorsJohn McCafferty, Andrew D. Griffiths, Greg Winter, David J. Chiswell Journal Nature 348: 552-554 (1990) (1990)
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• Gene technologies for antibody engineering AuthorsG. Winter Journal Behring Inst. Mitt. 87: 10-20 (1990) (1990)
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• Secretion of a homodimeric V(alpha))C(k) T-cell receptor-immunoglobulin chimeric protein AuthorsRoy A. Mariuzza, Greg Winter Journal Journal of Biological Chemistry 264: 7310-7316 (1989) (1989)
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• The immunogenicity of chimeric antibodies AuthorsMarianne Bruggemann, Greg Winter, Herman Waldmann, Michael S. Neuberger Journal J. Exp. Med. 170: 2153-2157 (1989) (1989)
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• Cloning immunoglobulin variable domains for expression by the polymerase chain reaction AuthorsRosaria Orlandi, Detlef H. Gussow, Peter T. Jones, Greg Winter Journal Proceedings of the National Academy of Sciences, USA 86: 3833-3837 (1989) (1989)
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• Blood clearance in the mouse of an aglycosyl recombinant monoclonal antibody AuthorsEdward J. Wawrzynczak, Geoffrey D. Parnell, Alan J. Cumber, Peter T. Jones, Greg Winter Journal Biochemical Society Transactions 17: 1061-1062 (1989) (1989)
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• 'Sticky feet'-directed mutagenesis and its application to swapping antibody domains AuthorsTim Clackson, Greg Winter Journal Nucleic Acids Research 17: 10163-10170 (1989) (1989)
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• Antibody engineering AuthorsG. P. Winter Journal Phil. Trans. R. Soc. Lond. B 324: 537-547 (1989) (1989)
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• Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli AuthorsE. Sally Ward, Detlef Gussow, Andrew D. Griffiths, Peter T. Jones, Greg Winter Journal Nature 341: 544-546 (1989) (1989)
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• The engineering of enzymes and antibodies AuthorsGreg Winter Journal Texte de la Conference presentee par Monsieur Greg Winter a l'occasion de la remise du Prix Louis Jeantet de Medecine le 21 Avril 1989 a Geneve (1989) (1989)
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• Localization of the binding site for the human high-affinity Fc receptor on IgG AuthorsAlexander R. Duncan, Jennifer M. Woof, Lynda J. Partridge, Dennis R. Burton, Greg Winter Journal Nature 332: 563-564 (1988) (1988)
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• Reshaping human antibodies: grafting an antilysozyme activity AuthorsMartine Verhoeyen, Cesar Milstein, Greg Winter Journal Science 239: 1534-1536 (1988) (1988)
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• Reshaping human antibodies for therapy AuthorsLutz Riechmann, Michael Clark, Herman Waldmann, Greg Winter Journal Nature 332: 323-327 (1988) (1988)
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• Expression of an antibody Fv fragment in myeloma cells AuthorsLutz Riechmann, Jefferson Foote, Greg Winter Journal Journal of Molecular Biology 203: 825-828 (1988) (1988)
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• Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1H AuthorsG. Hale, M. J. S. Dyer, M. R. Clark, J. M. Phillips, R. Marcus, L. Riechmann, G. Winter, H. Waldmann Journal Lancet 17 December, pp.1394-1399 (1988) (1988)
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• Reconstruction by site-directed mutagenesis of the transition state for the activation of tyrosine by the tyrosyl-tRNA synthetase: a mobile loop envelopes the transition state in an induced-fit mechanism AuthorsAlan R. Fersht, Jack W. Knill-Jones, Hugues Bedouelle, Greg Winter Journal Biochemistry 27: 1581-1587 (1988) (1988)
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• The binding site for Clq on IgG AuthorsAlexander R. Duncan, Greg Winter Journal Nature 332: 738-740 (1988) (1988)
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• Structure-activity relationships in engineered proteins: characterization of disruptive deletions in the alpha-ammonium group binding site of tyrosyl-tRNA synthetase AuthorsLowe D. M., Winter G., Fersht A. R. Journal Biochemistry 26(19):6038-6043. 22 September 1987 (1987)
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  DOI10.1021/bi00393a014 PMID3480006 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Replacing the complementarity-determining regions in a human antibody with those from a mouse AuthorsPeter T. Jones, Paul H. Dear, Jefferson Foote, Michael S. Neuberger, Greg Winter Journal Nature 321: 522-525 (1986) (1986)
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• Construction of heterodimer tyrosyl-tRNA synthetase shows tRNA(Tyr) interacts with both subunits AuthorsPaul Carter, Hugues Bedouelle, Greg Winter Journal Proceedings of the National Academy of Sciences, USA 83: 1189-1192 (1986) (1986)
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• A model of synthetase/transfer RNA interaction as deduced by protein engineering AuthorsHugues Bedouelle, Greg Winter Journal Nature 320:371-373 (1986) (1986)
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• Protein engineering of tyrosyl-tRNA synthetase: the charging of tRNA AuthorsBedouelle H., Carter P., Winter G. Journal Philosophical Transcations of the Royal Society of London, A 317: 433-439 (1986) (1986)
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• Manual sequencing by the Dansyl-Edman reaction AuthorsGreg Winter Journal In: Practical Protein Chemistry - A Handbook (Edited by A. Darbre) John Wiley & Sons Ltd pp.367-374 (1986) (1986)
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• Manual sequence strategy - a personal view AuthorsGreg Winter Journal In: Practical Protein Chemistry - A Handbook (Edited by A. Darbre) John Wiley & Sons Ltd pp.345-366 (1986) (1986)
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• A transcription termininator in the 5' non-coding region of the tyrosyl tRNA synthetase gene from Bacillus stearothermophilus AuthorsMary M. Y. Waye, Greg Winter Journal Eur. J. Biochem. 158: 505-510 (1986) (1986)
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• Reduced heat resistance of mutant spores after cloning and mutagenesis of the Bacillus subtilis gene encoding penicillin-binding protein 5 AuthorsJohn A. Todd, Anne N. Roberts, Keith Johnstone, Patrick J. Piggot, Greg Winter, David J. Ellar Journal Journal of Bacteriology 167: 257-264 (1986) (1986)
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• EcoK selection vectors for shotgun cloning into M13 and deletion mutagenesis AuthorsMary M. Y. Waye, Martine E. Verhoeyen, Peter T. Jones, Greg Winter Journal Nucleic Acids Research 13(23):8561-8571 (1985) (1985)
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  DOI10.1093/nar/13.23.8561 PMID3001643 PMCIDPMC322152 Division 
• Hydrogen bonding and biological specificity analysed by protein engineering AuthorsAlan R. Fersht, Jian-Ping Shi, Jack Knill-Jones, Denise M. Lowe, Anthony J. Wilkinson, David M. Blow, Peter Brick, Paul Carter, Mary M. Y. Waye, Greg Winter Journal Nature 314: 235-238 (1985) (1985)
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• Improved oligonucleotide site-directed mutagenesis using M13 vectors AuthorsPaul Carter, Hugues Bedouelle, Greg Winter Journal Nucleic Acids Research 13: 4431-4443 (1985) (1985)
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• Engineering of tyrosyl tRNA synthetase AuthorsHugues Bedouelle, Paul Carter, Mary M. Y. Waye, Greg Winter, Denise M. Lowe, Anthony J. Wilkinson, Alan R. Fersht Journal Biochimie 67: 737-743 (1985) (1985)
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• Probing histidine-substrate interactions in tyrosyl-tRNA synthetase using asparagine and glutamine replacements AuthorsDenise M. Lowe, Alan R. Fersht, Anthony J. Wilkinson, Paul Carter, Greg Winter Journal Biochemistry 24: 5106-5109 (1985) (1985)
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• Transition-state stabilization in the mechanism of tyrosyl-tRNA synthetase revealed by protein engineering AuthorsRobin J. Leatherbarrow, Alan R. Fersht, Greg Winter Journal Proceedings of the National Academy of Sciences, USA 82: 7840-7844 (1985) (1985)
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• Reversible dissociation of dimeric tyrosyl-tRNA synthetase by mutagenesis at the subunit interface AuthorsD. Hugh Jones, Andrew J. McMillan, Alan R. Fersht, Greg Winter Journal Biochemistry 24: 5852-5857 (1985) (1985)
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• Fine structure-activity analysis of mutations at position 51 of tyrosyl-tRNA synthetase AuthorsAlan R. Fersht, Anthony J. Wilkinson, Paul Carter, Greg Winter Journal Biochemistry 24: 5858-5861 (1985) (1985)
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• Redesigning enzymes by site-directed mutagenesis AuthorsA. R. Fersht, G. P. Winter Journal Ciba Foundation Symposium (Enzymes in organic synthesis) 111: 204-218 (1985) (1985)
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• Oligonucleotide site-directed mutagenesis in M13. An experimental manual. Based on a practical course held at EMBL Heidelberg in Sep 1984 AuthorsPaul Carter, Hugues Bedouelle, Mary M. Y. Waye, Greg Winter Journal Monograph : Anglian Biotechnology Limited pp.1-30 (1985)
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• Genetic dissection of tyrosyl-tRNA synthetase AuthorsGreg Winter, Paul Carter, Mary M. Y. Waye, D. M. Blow, Anthony J. Wilkinson, J.-P. Shi, Alan R. Fersht Journal Biochemical Society Transactions 12: 224-225 (1984) (1984)
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• A large increase in enzyme-substrate affinity by protein engineering AuthorsAnthony J. Wilkinson, Alan R. Fersht, D. M. Blow, Paul Carter, Greg Winter Journal Nature 307: 187-188 (1984) (1984)
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• Sequence rearrangements in influenza virus RNA and ribonucleoprotein structure AuthorsJames S. Robertson, Philip A. Jennings, John T. Finch, Greg Winter Journal Segmented Negative Strand Viruses. Academic Press Inc pp.65-72 (1984) (1984)
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• Studying enzyme-substrate interactions by site-directed mutagenesis AuthorsAlan R. Fersht, Greg Winter Journal Pontificiae Academiae Scientiarum Scripta Varia (Abstracts of the Proceedings of the Working Group on: Specificity in Biological Interactions) 55: 123-132 (1984) (1984)
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• Analysis of enzyme structure and activity by protein engineering AuthorsAlan R. Fersht, Jian-Ping Shi, Anthony J. Wilkinson, David M. Blow, Paul Carter, Mary M. Y. Waye, Greg P. Winter Journal Angewandte Chemie International Edition 23: 467-473 (1984) (1984)
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• The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus) AuthorsPaul J. Carter, Greg Winter, Anthony J. Wilkinson, Alan R. Fersht Journal Cell 38: 835-840 (1984) (1984)
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• Engineering enzymes AuthorsGreg Winter, Alan R. Fersht Journal Trends in Biotechnology 2: 115-119 (1984) (1984)
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• Does the higher order structure of the influenza virus ribonucleoprotein guide sequence rearrangements in influenza viral RNA? AuthorsPhilip A. Jennings, John T. Finch, Greg Winter, James S. Robertson Journal Cell 34(2):619-627 (1983) (1983)
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• The amino acid sequence of the tyrosyl-tRNA synthetase from Bacillus stearothermophilus AuthorsGreg Winter, Gordon L. E. Koch, Brian S. Hartley, David G. Barker Journal Eur. J. Biochem. 132: 383-387 (1983) (1983)
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• Site-directed mutagenesis as a probe of enzyme structure and catalysis: tyrosyl-tRNA synthetase cysteine-35 to glycine-35 mutation AuthorsAnthony J. Wilkinson, Alan R. Fersht, David M. Blow, Greg Winter Journal Biochemistry 22: 3581-3586 (1983) (1983)
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• Deletion mutagenesis using an 'M13 splint': the N-terminal structural domain of tyrosyl-tRNA synthetase (B. stearothermophilus) catalyses the formation of tyrosyl adenylate AuthorsMary M. Y. Waye, Greg Winter, Anthony J. Wilkinson, Alan R. Fersht Journal EMBO Journal 2: 1827-1929 (1983) (1983)
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• Nucleotide sequence of human influenza A/PR/8/34 segment 2 AuthorsGreg Winter, Stan Fields Journal Nucleic Acids Research 10: 2135-2143 (1982) (1982)
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• Nucleotide sequences of influenza virus segments 1 and 3 reveal mosaic structure of a small viral RNA segment AuthorsStan Fields, Greg Winter Journal Cell 28: 303-313 (1982) (1982)
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• Conserved cysteine and histidine residues in the structures of the tyrosyl and methionyl-tRNA synthetases AuthorsD. G. Barker, G. Winter Journal FEBS Letters 145: 191-193 (1982) (1982)
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• Redesigning enzyme structure by site-directed mutagenesis: tyrosyl tRNA synthetase and ATP binding AuthorsGreg Winter, Alan R. Fersht, Anthony J. Wilkinson, Mark Zoller, Michael Smith Journal Nature 299: 756-758 (1982) (1982)
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• The tyrosyl-tRNA synthetase from Escherichia coli . Complete nucleotide sequence of the structural gene AuthorsD. G. Barker, C. J. Bruton, G. Winter Journal FEBS Letters 150: 419-423 (1982) (1982)
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• Structure of the neuraminidase gene in human influenza virus A/PR/8/34 AuthorsFields S., Winter G., Brownlee G. G. Journal Nature 290(5803):213-217. 19 March 1981 (1981)
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  DOI10.1038/290213a0 PMID7010182 PMCID  DivisionProtein & Nucleic Acid Chemistry
• The use of synthetic oligodeoxynucleotide primers in cloning and sequencing segment 8 of influenza virus (A/PR/8/34) AuthorsGreg Winter, Stan Fields, Michael J. Gait, George G. Brownlee Journal Nucleic Acids Research 9: 237-245 (1981) (1981)
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• The structure of two subgenomic RNAs from human influenza virus A/PR/8/34 AuthorsGreg Winter, Stan Fields, Giulio Ratti Journal Nucleic Acids Research 9: 6907-6915 (1981) (1981)
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• Nucleotide sequence of the haemagglutinin gene of a human influenza virus H1 subtype AuthorsGreg Winter, Stan Fields, George G. Brownlee Journal Nature 292: 72-75 (1981) (1981)
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• The structure of the gene encoding the nucleoptotein of human influenza virus A/PR/8/34 AuthorsGreg Winter, Stan Fields Journal Virology 114: 423-428 (1981) (1981)
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• Nucleotide-sequence heterogeneity and sequence rearrangements in influenza virus cDNA AuthorsStan Fields, Greg Winter Journal Gene 15: 207-214 (1981) (1981)
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• Influenza virus A/PR/8/34 genes: squencing by a shotgun approach AuthorsStan Fields, Greg Winter Journal Genetic Variation Among Influenza Viruses. Academic Press, Inc. pp.55-64 (1981) (1981)
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• The haemagglutinin gene of influenza A/PR/8/34 AuthorsGeorge G. Brownlee, Greg Winter, Stan Fields Journal Genetic Variation Among Influenza Viruses. Academic Press, Inc. pp.65-75 (1981) (1981)
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• Cloning of influenza cDNA into M13: the sequence of the RNA segment encoding the A/PR/8/34 matrix protein AuthorsGreg Winter, Stan Fields Journal Nucleic Acids Research 8: 1965-1974 (1980) (1980)
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• Large-scale isolation of enzymes from Bacillus stearothermophilus AuthorsAtkinson T., Banks G. T., Bruton C. J., Comer M. J., Jakes R., Kamalagharan T., Whitaker A. R., Winter G. P. Journal Journal of Applied Biochemistry 1: 247-258 (1979) (1979)
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• The tryptophanyl- and tyrosyl-tRNA synthetases from Bacillus stearothermophilus AuthorsWinter G., Koch G. L. E., Dell A., Hartley B. S. Journal Transfer RNA: Structure, Properties, and Recognition. Cold Spring Harbor Laboratory pp.255-265 (1979) (1979)
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• 3' end labelling of RNA with 32P suitable for rapid gel sequencing AuthorsG. Winter, G. G. Brownlee Journal Nucleic Acids Research 5: 3129-3140 (1978) (1978)
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• Chemical modification AuthorsG. Winter, A. Dell Journal In: Amino-acids, Peptides and Proteins (Special Periodical Reports Vol.9), The Chemical Society, London pp.114-196 (1978) (1978)
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• The amino acid sequence of tryptophanyl tRNA synthetase fromBacillus stearothermophilus AuthorsG. P. Winter, B. S. Hartley Journal FEBS Letters 80: 340-342 (1977) (1977)
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• Sequence homologies between the tryptophanyl tRNA synthetases of Bacillus stearothermophilus and Escherichia coli AuthorsG. P. Winter, B. S. Hartley, A. D. McLachlan, M. Lee, K. H. Muench Journal FEBS Letters 82: 348-350 (1977) (1977)
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• Structural investigations of peptides and proteins. I: Primary structure and chemical modification AuthorsI. D. Walker, G. Winter, D. J. Worthington, H. Muirhead, R. H. Pain Journal In: Amino-acids, Peptides and Proteins (Special Periodical Reports Vol.8), The Chemical Society, London pp.29-151 (1976) (1976)
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