Published Research
Found 103 results for Tate C.
- De novo design of miniproteins targeting GPCRs AuthorsMuratspahić E., Feldman D., Kim D. E., Qu X., Bratovianu A. M., Rivera-Sánchez P., Voss J. H., Hertz E. P. T., Jeppesen M., Dimitri F., Sakamoto K., Nallathambi A., Peceli P., Cao J., Cary B. P., Belousoff M. J., Keov P., Trinh P. N. H., Chen Q., Ren Y., Fine J., Mishra S., Dalal A., Sinha S., Banerjee R., Ganguly M., Karuppusamy K. V., Sappington I., Schlichthaerle T., Zhang J. Z., Pillai A., Coventry B., Mihaljević L., Bauer M., Torres S. V., Motmaen A., Lee G. R., Tran L., Wang X., Goreshnik I., Vafeados D. K., Svendsen J. E., Hosseinzadeh P., Lindegaard N., Brandt M., Waltenspühl Y., Deibler K., Deweid L., Bennett A., Schöppe J., Dong T., Yan X., Oostdyk L., Cao W., Anantharaman L., Weisser J. J., Bastlund J. F., Bundgaard C., Asuni A. A., English J. G., Stewart L., Halloran L., Spangler J. B., Lieber A., Shukla A. K., Sexton P. M., Roth B. L., Krumm B. E., Wootten D., Tate C. G., Norn C., Baker D. Journal Nature (2026)
- aGPCR-HEK: a stable high-expression inducible mammalian cell expression system for adhesion GPCR structural biology applications AuthorsFavara D. M., Tate C. G. Journal Bio‑protocol 16(5):e5621 (2026)
- Purification of the active-state G protein-coupled receptor ADGRL4 for cryo-electron microscopy using a modular tag system and a tethered mini‑Gq AuthorsFavara D. M., Tate C. G. Journal Bio‑protocol 16(5):e5617 (2026)
- Insights from aquaporin structures into drug-resistant sleeping sickness AuthorsMatusevicius M., Corey R. A., Gragera M., Yamashita K., Sprenger T., Ungogo M., Blaza J. N., Castro-Hartmann P., Chirgadze D. Y., Chaitanya Vedithi S., Afanasyev P., Melero R., Warshamanage R., Gusach A., Carazo J. M., Carrington M., Blundell T., Murshudov G. N., Stansfeld P. J., Sansom M. S. P., De Koning H. P., Tate C. G., Weyand S. Journal Elife 14:RP107460 (2026)
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Functional dynamics of G protein-coupled receptors reveal new routes for drug discovery
AuthorsConflitti P., Lyman E., Sansom M. S. P., Hildebrand P. W., Gutiérrez-de-Terán H., Carloni P., Ansell T. B., Yuan S., Barth P., Robinson A. S., Tate C. G., Gloriam D., Grzesiek S., Eddy M. T., Prosser S., Limongelli V.
Journal
Nature reviews. Drug Discovery
24(4):251-275 (2025)
Details
DOIdoi.org/10.1038/s41573-024-01083-3 PMID39747671 PMCIDPMC11968245 DivisionStructural Studies - VPS26 Moonlights as a β-Arrestin-like Adapter for a 7-Transmembrane RGS Protein in Arabidopsis thaliana AuthorsLou F., Zhou W., Tunc-Ozdemir M., Yang J., Velazhahan V., Tate C. G., Jones A. M. Journal Biochemistry (2024)
- Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f AuthorsGusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. Journal Nature Communications Aug 30;15(1):7555. (2024)
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Carvedilol activates a myofilament signaling circuitry to restore cardiac contractility in heart failure
AuthorsWang Y, Zhao M, Liu X, Xu B, Reddy GR, Jovanovic A, Wang Q, Zhu C, Xu H, Bayne EF, Xiang W, Tilley DG, Ge Y, Tate CG, Feil R, Chiu JC, Bers DM, Xiang YK.
Journal
JACC. Basic to Translational Science
9(8):982-1001 (2024)
Details
DOIdoi.org/10.1016/j.jacbts.2024.03.007 PMID39297139 PMCIDPMC11405995 DivisionStructural Studies - Structures of Adrenoceptors AuthorsHelfinger L, Tate CG. Journal Handbook of Experimental Pharmacology (Book) 10.1007/164_2023_674 (2023)
- New insights into GPCR coupling and dimerisation from cryo-EM structures AuthorsGusach A., García-Nafría J., Tate C. G. Journal Current Opinion in Structural Biology 80:102574 (2023)
- New insights into GPCR coupling and dimerisation from cryo-EM structures AuthorsGusach A., García-Nafría J., Tate C. G. Journal Current Opinion in Structural Biology PMC10423944 (2023)
- Developing novel antifungals: lessons from G protein-coupled receptors AuthorsVelazhahan V., McCann B. L., Bignell E., Tate C. G. Journal Trends in Pharmacological Sciences 44(3):162-174 (2023)
- Activation mechanism of the class D fungal GPCR dimer Ste2 AuthorsVelazhahan V., Ma N., Vaidehi N., Tate C. G. Journal Nature 603(7902):743-748 (2022)
- Structure determination of GPCRs: cryo-EM compared with X-ray crystallography AuthorsGarcía-Nafría J., Tate C. G. Journal Biochemical Society Transactions 49(5):2345-2355 (2021)
- Structure of the class D GPCR Ste2 dimer coupled to two G proteins AuthorsVelazhahan V., Ma N., Pándy-Szekeres G., Kooistra A. J., Lee Y., Gloriam D. E., Vaidehi N., Tate C. G. Journal Nature 589(7840):148-153. & January 2021 (2021)
- Molecular basis of β-arrestin coupling to formoterol-bound β1‑adrenoceptor AuthorsLee Y., Warne T., Nehmé R., Pandey S., Dwivedi-Agnihotri H., Chaturvedi M., Edwards P. C., García-Nafría J., Leslie A. G. W., Shukla A. K., Tate C. G. Journal Nature 583(7818):862-866. June 2020 (2020)
- How Do Branched Detergents Stabilize GPCRs in Micelles? AuthorsLee S., Ghosh S., Jana S., Robertson N., Tate C. G., Vaidehi N. Journal Biochemistry 59(23):2125-2134. 21 May 2020 (2020)
- Impact of GPCR Structures on Drug Discovery AuthorsCongreve M., de Graaf C., Swain N. A., Tate C. G. Journal Cell 181(1):81-91. 2 April 2020 (2020)
- Strategic Screening and Characterization of the Visual GPCR-mini-G Protein Signaling Complex for Successful Crystallization AuthorsPamula F., Mühle J., Blanc A., Nehmé R., Edwards P. C., Tate C. G., Tsai C. J. Journal Journal of Visualized Experiments : Jove 157:e60747. 16 March 2020 (2020)
- Cryo-Electron Microscopy: Moving Beyond X-Ray Crystal Structures for Drug Receptors and Drug Development AuthorsGarcía-Nafría J., Tate C. G. Journal Annual Review of Pharmacology and Toxicology 60:51-71. January 2020 (2020)
- Machine Learning for Prioritization of Thermostabilizing Mutations for G-Protein Coupled Receptors AuthorsMuk S., Ghosh S., Achuthan S., Chen X., Yao X., Sandhu M., Griffor M. C., Fennell K. F., Che Y., Shanmugasundaram V., Qiu X., Tate C. G., Vaidehi N. Journal Biophysical Journal 117(11):2228-2239. 3 December 2019 (2019)
- Identification of an alternating-access dynamics mutant of EmrE with impaired transport AuthorsWu C., Wynne S. A., Thomas N. E., Uhlemann E. M., Tate C. G., Henzler-Wildman K. A. Journal Journal of Molecular Biology 431(15):2777-2789. 12 July 2019 (2019)
- Molecular basis for high-affinity agonist binding in GPCRs AuthorsWarne T., Edwards P. C., Doré A. S., Leslie A. G. W., Tate C. G. Journal Science 364(6442):775-778. 24 May 2019 (2019)
- Cryo-EM structures of GPCRs coupled to Gs, Gi and Go AuthorsGarcía-Nafría J., Tate C. G. Journal Molecular and Cellular Endocrinology 488:1-13. 28 March 2019 (2019)
- Dynamic role of the G protein in stabilizing the active state of the adenosine A2A receptor AuthorsLee S., Nivedha A. K., Tate C. G., Vaidehi N. Journal Structure 27(4):703-712.e3. 31 January 2019 (2019)
- Crystal structure of rhodopsin in complex with a mini-Go sheds light on the principles of G protein selectivity AuthorsTsai C. J., Pamula F., Nehmé R., Mühle J., Weinert T., Flock T., Nogly P., Edwards P. C., Carpenter B., Gruhl T., Ma P., Deupi X., Standfuss J., Tate C. G., Schertler G. F. X. Journal Science Advances 4(9):eaat7052. September 2018 (2018)
- PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling AuthorsYen H. Y., Hoi K. K., Liko I., Hedger G., Horrell M. R., Song W., Wu D., Heine P., Warne T., Lee Y., Carpenter B., Plückthun A., Tate C. G., Sansom M. S. P., Robinson C. V. Journal Nature 559(7714):423-427. 19 July 2018 (2018)
- Cryo-EM structure of the serotonin 5-HT1B receptor coupled to heterotrimeric Go AuthorsGarcía-Nafría J., Nehmé R., Edwards P. C., Tate C. G. Journal Nature 558(7711):620-623. 28 June 2018 (2018)
- Cryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein AuthorsGarcía-Nafría J., Lee Y., Bai X., Carpenter B., Tate C. G. Journal ELife 7: e35946. 4 May 2018 (2018)
- Mini G protein probes for active G protein-coupled receptors (GPCRs) in live cells AuthorsWan Q., Okashah N., Inoue A., Nehmé R., Carpenter B., Tate C. G., Lambert N. A. Journal Journal of Biological Chemistry 293(19):7466-7473. 9 March 2018 (2018)
- Insight into partial agonism by observing multiple equilibria for ligand-bound and Gs-mimetic nanobody-bound β1-adrenergic receptor AuthorsSolt A. S., Bostock M. J., Shrestha B., Kumar P., Warne T., Tate C. G., Nietlispach D. Journal Nature Communications 8(1):1795. 27 November 2017 (2017)
- Active state structures of G protein-coupled receptors highlight the similarities and differences in the G protein and arrestin coupling interfaces AuthorsCarpenter B., Tate C. G. Journal Current Opinion in Structural Biology 45:124-132. August 2017 (2017)
- Strategy for the Thermostabilization of an Agonist-Bound GPCR Coupled to a G Protein AuthorsStrege A., Carpenter B., Edwards P. C., Tate C. G. Journal Methods in Enzymology 594:243-264. 19 July 2017 (2017)
- Structural biology: A receptor that might block itself AuthorsTate C. G. Journal Nature 544(7650):307-308. 20 April 2017 (2017)
- Mini-G proteins: Novel tools for studying GPCRs in their active conformation AuthorsNehmé R., Carpenter B., Singhal A., Strege A., Edwards P. C., White C. F., Du H., Grisshammer R., Tate C. G. Journal PloS one 12(4):e0175642. 20 April 2017 (2017)
- Expression, Purification and Crystallisation of the Adenosine A2A Receptor Bound to an Engineered Mini G Protein AuthorsCarpenter B., Tate C. G. Journal Bio‑protocol 7(8):e2234. 20 April 2017 (2017)
- Engineering a minimal G protein to facilitate crystallisation of G protein-coupled receptors in their active conformation AuthorsCarpenter B., Tate C. G. Journal Protein Engineering, Design & Selection : PEDS 29(12):583-594. December 2016 (2016)
- How Do Short Chain Nonionic Detergents Destabilize G-Protein-Coupled Receptors? AuthorsLee S., Mao A., Bhattacharya S., Robertson N., Grisshammer R., Tate C. G., Vaidehi N. Journal Journal of the American Chemical Society 138(47):15425-15433. 30 November 2016 (2016)
- Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region AuthorsVenkatakrishnan A. J., Deupi X., Lebon G., Heydenreich F. M., Flock T., Miljus T., Balaji S., Bouvier M., Veprintsev D. B., Tate C. G., Schertler G. F., Babu M. M. Journal Nature 536(7617):484-487. 25 August 2016 (2016)
- Structure of the adenosine A(2A) receptor bound to an engineered G protein AuthorsCarpenter B., Nehmé R., Warne T., Leslie A. G., Tate C. G. Journal Nature 536(7614):104-107. 4 August 2016 (2016)
- Generation of Tetracycline-Inducible Mammalian Cell Lines by Flow Cytometry for Improved Overproduction of Membrane Proteins AuthorsAndréll J., Edwards P. C., Zhang F., Daly M., Tate C. G. Journal Methods in Molecular Biology 1432:63-78 (2016)
- A mutagenesis and screening strategy to generate optimally thermostabilized membrane proteins for structural studies AuthorsMagnani F., Serrano-Vega M. J., Shibata Y., Abdul-Hussein S., Lebon G., Miller-Gallacher J., Singhal A., Strege A., Thomas J. A., Tate C. G. Journal Nature Protocols 11(8):1554-1571. August 2016 (2016)
- High-throughput screening and selection of mammalian cells for enhanced protein production AuthorsPriola J. J., Calzadilla N., Baumann M., Borth N., Tate C. G., Betenbaugh M. J. Journal Biotechnology Journal 11(7):853-865. July 2016 (2016)
- Complete Reversible Refolding of a G-Protein Coupled Receptor on a Solid Support AuthorsDi Bartolo N., Compton E. L., Warne T., Edwards P. C., Tate C. G., Schertler G. F., Booth P. J. Journal PloS one 11(3):e0151582. 16 March 2016 (2016)
- How Can Mutations Thermostabilize G-Protein-Coupled Receptors? AuthorsVaidehi N., Grisshammer R., Tate C. G. Journal Trends in Pharmacological Sciences 37(1):37-46. January 2016 (2016)
- Pharmacological Analysis and Structure Determination of 7-Methylcyanopindolol-Bound β1-Adrenergic Receptor AuthorsSato T., Baker J., Warne T., Brown G., Leslie A., Congreve M., Tate C. Journal Molecular Pharmacology 88(6):1024-1034. December 2015 (2015)
- Ligand occupancy in crystal structure of β1-adrenergic G protein-coupled receptor AuthorsLeslie A. G., Warne T., Tate C. G. Journal Nature Structural & Molecular Biology 22(12):941-942. December 2015 (2015)
- Identifying Thermostabilizing Mutations in Membrane Proteins by Bioinformatics AuthorsTate C. G. Journal Biophysical Journal 109(7):1307-1308. 6 October 2015 (2015)
- Isolation and characterisation of transport-defective substrate-binding mutants of the tetracycline antiporter TetA(B) AuthorsWright D. J., Tate C. G. Journal Biochimica et Biophysica Acta 1848(10 Pt A):2261-2270. October 2015 (2015)
- Universal allosteric mechanism for Gα activation by GPCRs AuthorsFlock T., Ravarani C. N., Sun D., Venkatakrishnan A. J., Kayikci M., Tate C. G., Veprintsev D. B., Babu M. M. Journal Nature 524(7564):173-179. 13 August 2015 (2015)
- GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014. AuthorsHeifetz A., Schertler G. F., Seifert R., Tate C. G., Sexton P. M., Gurevich V. V., Fourmy D., Cherezov V., Marshall F. H., Storer R. I., Moraes I., Tikhonova I. G., Tautermann C. S., Hunt P., Ceska T., Hodgson S., Bodkin M. J., Singh S., Law R. J., Biggin P. C. Journal Naunyn-Schmiedeberg's Archives of Pharmacology 388(8):883-903. August 2015 (2015)
- Molecular Determinants of CGS21680 Binding to the Human Adenosine A2A Receptor. AuthorsLebon G., Edwards P. C., Leslie A. G., Tate C. G. Journal Molecular Pharmacology 87(6):907-915. 01 June 2015 (2015)
- Advances in membrane protein crystallography: in situ and in meso data collection AuthorsWeyand S., Tate C. G. Journal Acta Crystallographica. Section D, Biological Crystallography 71(Pt 6):1226-1227. June 2015 (2015)
- Structural Dynamics and Thermostabilization of Neuro-tensin Receptor 1. AuthorsLee S., Bhattacharya S., Tate C. G., Grisshammer R., Vaidehi N. Journal The Journal of Physical Chemistry. B 119(15):4917-4928. 16 April 2015 (2015)
- Purification and Crystallization of a Thermostabilized Agonist-Bound Conformation of the Human Adenosine A(2A) Receptor AuthorsTate C. G., Lebon G. Journal Methods in Molecular Biology 1335:17-27. January 2015 (2015)
- Quality control in eukaryotic membrane protein overproduction AuthorsThomas J., Tate C. G. Journal Journal of Molecular Biology 426(24):4139-4154. 12 December 2014 (2014)
- Rapid Computational Prediction of Thermostabilizing Mutations for G Protein-Coupled Receptors AuthorsBhattacharya S., Lee S., Grisshammer R., Tate C. G., Vaidehi N. Journal Journal of Chemical Theory and Computation 10(11):5149-5160. 11 November 2014 (2014)
- Editorial overview: New constructs and expression of proteins: Making things better AuthorsTakagi J., Tate C. G. Journal Current Opinion in Structural Biology 26:iv-vi. June 2014 (2014)
- Dynamic behavior of the active and inactive states of the adenosine A(2A) receptor AuthorsLee S., Bhattacharya S., Grisshammer R., Tate C., Vaidehi N. Journal Journal of Physical Chemistry. B 118(12):3355-3365. 27 March 2014 (2014)
- The 2.1 A resolution structure of cyanopindolol-bound β1-adrenoceptor identifies an intramembrane Na+ ion that stabilises the ligand-free receptor AuthorsMiller-Gallacher J. L., Nehmé R., Warne T., Edwards P. C., Schertler G. F., Leslie A. G., Tate C. G. Journal PloS one 9(3):e92727. 24 March 2014 (2014)
- Rare coding variants of the adenosine A3 receptor are increased in autism: on the trail of the serotonin transporter regulome AuthorsCampbell N. G., Zhu C. B., Lindler K. M., Yaspan B. L., Kistner-Griffin E., NIH ARRA Consortium , Hewlett W. A., Tate C. G., Blakely R. D., Sutcliffe J. S. Journal Molecular Autism 4(1):28. 16 August 2013 (2013)
- Thermostabilisation of the serotonin transporter in a cocaine-bound conformation AuthorsAbdul-Hussein S., Andréll J., Tate C. G. Journal Journal of Molecular Biology 425(12):2198-2207. 26 June 2013 (2013)
- Thermostabilization of the β1-adrenergic receptor correlates with increased entropy of the inactive state AuthorsNiesen M. J., Bhattacharya S., Grisshammer R., Tate C. G., Vaidehi N. Journal Journal of Physical Chemistry. B 117(24):7283-7291. 20 June 2013 (2013)
- Biophysical fragment screening of the β1-adrenergic receptor: identification of high affinity arylpiperazine leads using structure-based drug design AuthorsChristopher J. A., Brown J., Doré A. S., Errey J. C., Koglin M., Marshall F. H., Myszka D. G., Rich R. L., Tate C. G., Tehan B., Warne T., Congreve M. Journal Journal of Medicinal Chemistry 56(9):3446-3455. 9 May 2013 (2013)
- Pharmacology and structure of isolated conformations of the adenosine A₂A receptor define ligand efficacy AuthorsBennett K. A., Tehan B., Lebon G., Tate C. G., Weir M., Marshall F. H., Langmead C. J. Journal Molecular Pharmacology 83(5):949-958. May 2013 (2013)
- Optimising the combination of thermostabilising mutations in the neurotensin receptor for structure determination AuthorsShibata Y., Gvozdenovic-Jeremic J., Love J., Kloss B., White J. F., Grisshammer R., Tate C. G. Journal Biochimica et Biophysica Acta 1828(4):1293-1301. April 2013 (2013)
- Molecular signatures of G-protein-coupled receptors AuthorsVenkatakrishnan A. J., Deupi X., Lebon G., Tate C. G., Schertler G. F., Babu M. M. Journal Nature 494(7436):185-194. 14 February 2013 (2013)
- Overexpression of membrane proteins in mammalian cells for structural studies AuthorsAndréll J., Tate C. G. Journal Molecular Membrane Biology 30(1):52-63. February 2013 (2013)
- The importance of interactions with helix 5 in determining the efficacy of β-adrenoceptor ligands AuthorsWarne T., Tate C. G. Journal Biochemical Society Transactions 41(1):159-165. February 2013 (2013)
- Structure of the agonist-bound neurotensin receptor AuthorsWhite J. F., Noinaj N., Shibata Y., Love J., Kloss B., Xu F., Gvozdenovic-Jeremic J., Shah P., Shiloach J., Tate C. G., Grisshammer R. Journal Nature 490(7421):508-513. 25 October 2012 (2012)
- [G protein-coupled receptors in the spotlight] AuthorsLebon G., Tate C. G. Journal Medecine Sciences 28(10):876-882. October 2012 (2012)
- A crystal clear solution for determining G-protein-coupled receptor structures AuthorsTate C. G. Journal Trends in Biochemical Sciences 37(9):343-352. September 2012 (2012)
- Agonist-bound structures of G protein-coupled receptors AuthorsLebon G., Warne T., Tate C. G. Journal Current Opinion in Structural Biology 22(4):482-490. August 2012 (2012)
- Outrunning free radicals in room-temperature macromolecular crystallography AuthorsOwen R. L., Axford D., Nettleship J. E, Owens R. J., Robinson J. I, Morgan A. W., Doré A. S., Lebon G., Tate C. G., Fry E. E., Ren J., Stuart D. I., Evans G. Journal Acta Crystallographica. Section D, Biological Crystallography 68(Pt 7):810-818. July 2012 (2012)
- Crystal structures of a stabilized β1-adrenoceptor bound to the biased agonists bucindolol and carvedilol AuthorsWarne T., Edwards P. C., Leslie A. G., Tate C. G. Journal Structure 20(5):841-849. 9 May 2012 (2012)
- [Structure of the adenosine-bound conformation of the human adenosine A(2A) receptor] AuthorsLebon G., Tate C. G. Journal Medecine Sciences 27(11):926-928. 30 November 2011 (2011)
- Engineering an ultra-thermostable β(1)-adrenoceptor AuthorsMiller J. L., Tate C. G. Journal Journal of Molecular Biology 413(3):628-638. 28 October 2011 (2011)
- The pharmacological effects of the thermostabilising (m23) mutations and intra and extracellular (β36) deletions essential for crystallisation of the turkey β-adrenoceptor AuthorsBaker J. G., Proudman R. G., Tate C. G. Journal Naunyn-Schmiedeberg's Archives of Pharmacology 384(1):71-91. July 2011 (2011)
- Thermostabilisation of an agonist-bound conformation of the human adenosine A(2A) receptor AuthorsLebon G., Bennett K., Jazayeri A., Tate C. G. Journal Journal of Molecular Biology 409(3):298-310. 10 June 2011 (2011)
- Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation AuthorsLebon G., Warne T., Edwards P. C., Bennett K., Langmead C. J,. Leslie A. G., Tate C. G. Journal Nature 474(7352):521-525. 18 May 2011 (2011)
- Two distinct conformations of helix 6 observed in antagonist-bound structures of a beta1-adrenergic receptor AuthorsMoukhametzianov R., Warne T., Edwards P. C., Serrano-Vega M. J., Leslie A. G., Tate C. G., Schertler G. F. Journal Proceedings of the National Academy of Sciences, USA 108(20):8228-8232. 17 May 2011 (2011)
- Overcoming barriers to membrane protein structure determination AuthorsBill R. M., Henderson P. J., Iwata S., Kunji E. R., Michel H., Neutze R., Newstead S., Poolman B., Tate C. G., Vogel H. Journal Nature Biotechnology 29(4):335-340. April 2011 (2011)
- A class of mild surfactants that keep integral membrane proteins water-soluble for functional studies and crystallization AuthorsHovers J., Potschies M., Polidori A., Pucci B., Raynal S., Bonneté F., Serrano-Vega M. J., Tate C. G., Picot D., Pierre Y., Popot J. L., Nehmé R., Bidet M., Mus-Veteau I., Busskamp H., Jung K. H., Marx A., Timmins P. A., Welte W. Journal Molecular Membrane Biology 28(3):171-181. April 2011 (2011)
- The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor AuthorsWarne T., Moukhametzianov R., Baker J. G., Nehmé R., Edwards P. C., Leslie A. G., Schertler G. F., Tate C. G. Journal Nature 469(7329):241-244. 13 January 2011 (2011)
- Growth and excitement in membrane protein structural biology AuthorsTate C. G., Stevens R. C. Journal Current Opinion in Structural Biology 20(4):399-400. 1 August 2010 (2010)
- Membrane protein gymnastics AuthorsTate C. G. Journal Science 328(5986):1644-1645. 25 June 2010 (2010)
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Three-dimensional structure of TspO by electron cryomicroscopy of helical crystals
AuthorsKorkhov V. M., Sachse C., Short J. M., Tate C. G.
Journal
Structure
18(6):677-687. 9 June 2010 (2010)
Details
DOI10.1016/j.str.2010.03.001 PMID20541505 PMCIDPMC2911597 DivisionProtein & Nucleic Acid Chemistry, Structural Studies - Practical considerations of membrane protein instability during purification and crystallisation AuthorsTate C. G. Journal Methods in Molecular Biology 601: 187-203. 2010 (2010)
- Development and crystallization of a minimal thermostabilized G protein-coupled receptor AuthorsWarne T., Serrano-Vega M. J., Tate C. G., Schertler G. F. X. Journal Protein Expression & Purification 65(2):204-213. June 2009 (2009)
- An emerging consensus for the structure of EmrE AuthorsKorkhova V. M., Tate C. G. Journal Acta Crystallographica Section D 65(2): 186-192. 1 February 2009 (2009)
- Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions AuthorsNelson P Barrera, Shoshanna C Isaacson, Min Zhou, Vassiliy N Bavro, Alex Welch, Theresia A Schaedler, Markus A Seeger, Ricardo Núñez Miguel, Vladimir M Korkhov, Hendrik W van Veen, Henrietta Venter, Adrian R Walmsley, Christopher G Tate, Carol V Robinson Journal Nature Methods 6(8):585-587 (2009) (2009)
- Transferability of thermostabilizing mutations between beta-adrenergic receptors AuthorsSerrano-Vega M. J., Tate C. G. Journal Molecular Membrane Biology 26(8):385-396 (2009) (2009)
- Co-evolving stability and conformational homogeneity of the human adenosine A2a receptor AuthorsMagnani F., Shibata Y., Serrano-Vega M. J., Tate C. G. Journal Proceedings of the National Academy of Sciences of the United States of America 105(31):10744-10749 (2008)
- Conformational thermostabilization of the beta1-adrenergic receptor in a detergent-resistant form AuthorsSerrano-Vega M. J., Magnani F., ShibataY., Tate C. G. Journal Proceedings of the National Academy of Sciences of the United States of America 105(3):877-882 (2008)
- Interactions with other human UDP-glucuronosyltransferases attenuate the consequences of the Y485D mutation on the activity and substrate affinity of UGT1A6 AuthorsKurkela M., Patana A-S., Mackenzie P. I., Court M., Tate C. G., Hirvonen J., Goldman A., Finel M. Journal Pharmacogenet. Genomics 17(2):115-126 (2007) (2007)
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Correcting for the buoyancy of macromolecules: density increments and apparent partial specific volumes with particular reference to the study of membrane proteins.
AuthorsButler P. J. G., Tate C. G.
Journal
Analytical Ultracentrifugation: Techniques and Methods (Scott, D., Harding, S., Rowe, A., eds) Royal Society of Chemistry
pp.131-151 (2005) (2005)
Details
DOI PMID PMCID DivisionStructural Studies -
Drug binding revealed by tandem mass spectrometry of a protein-micelle complex
AuthorsLeopold L. Ilag, Iban Ubarretxena-Belandia, Christopher G. Tate, Carol V. Robinson
Journal
J. Am. Chem. Soc.
126: 14362-14363 (2004) (2004)
Details
DOI PMID PMCID Division - Calreticulin promotes folding/dimerization of human lipoprotein lipase expressed in insect cells (Sf21) AuthorsZhang L., Wu G., Tate C. G., Lookene A., Olivecrona G. Journal Journal of Biological Chemistry 278(31):29344-29351. 1 August 2003 (2003)
- Overexpression of mammalian integral membrane proteins for structural studies AuthorsTate C. G. Journal FEBS Letters 504(3):94-98. 31 August 2001 (2001)
- Biophysical characterization of the cocaine binding pocket in the serotonin transporter using a fluorescent cocaine analogue as a molecular reporter AuthorsRasmussen S. G. F., Carroll F. I., Maresch M. J., Jensen A. D., Tate C. G., Gether U. Journal Journal of Biological Chemistry 276(7):4717-4723. 16 February 2001 (2001)
- The projection structure of EmrE, a proton-linked multidrug transporter from Escherichia coli, at 7 angstroms resolution AuthorsTate C. G., Kunji E. R. S., Lebendiker M., Schuldiner S. Journal EMBO Journal 20(1-2):77-81 (2001)
- The projection structure of EmrE, a proton-linked multidrug transporter from Escherichia coli, at 7 Angstrom resolution AuthorsTate C. G., Kunji E. R. S., Lebendiker M., Schuldiner S. Journal EMBO Journal 20(1-2):77-81. 15 January 2001 (2001)
- Molecular chaperones stimulate the functional expression of the cocaine-sensitive serotonin transporter AuthorsTate C. G., Whiteley E., Betenbaugh M. J. Journal Journal of Biological Chemistry 274(25):17551-17558 (1999) (1999)