Published Research

Found 77 results for Sutherland.

• Crystal structure of a tRNA acceptor-stem mimic at 1.94 Å resolution AuthorsZiwei Liu, Dom Bellini, Fabrice Gorrec, Armin Wagner, Kamel El Omari, John D. Sutherland Journal Acta Crystallogr F Struct Biol Commun 82(Pt 2):57-65 (2026)
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  DOI10.1107/S2053230X26000658 PMID41608807 PMCIDPMC12865779 DivisionProtein & Nucleic Acid Chemistry
• Indirect formation of peptide bonds as a prelude to ribosomal transpeptidation AuthorsDale H. J. A., Sutherland J. D. Journal J Am Chem Soc 147(1):305-317 (2025)
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  DOI10.1021/jacs.4c10326 PMID39693575 PMCIDPMC11726440 DivisionProtein & Nucleic Acid Chemistry
• RNA-directed peptide synthesis across a nicked loop AuthorsSu M., Roberts S. J., Sutherland J. D. Journal Nucleic Acids Research 52(19):11415-11422 (2024)
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  DOI10.1093/nar/gkae702 PMID39164017 PMCIDPMC11514466 DivisionProtein & Nucleic Acid Chemistry
• Prebiotic synthesis of dihydrouridine by photoreduction of uridine in formamide AuthorsXu J, Janicki MJ, Szabla R, Sutherland JD. Journal Chemical Communications 10.1039/d4cc01823k (2024)
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  DOI10.1039/d4cc01823k PMID38896044 PMCIDPMC11223185 DivisionProtein & Nucleic Acid Chemistry
• Manganese(II) promotes prebiotically plausible non-enzymatic RNA ligation reactions AuthorsLiu Z, Jiang CZ, Bond AD, Tosca NJ, Sutherland JD. Journal Chemical Communications (Cambridge) Chem Commun (Camb). 2024 Jun 20;60(51):6528-6531. doi: 10.1039/d4cc01086h. (2024)
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  DOI10.1039/d4cc01086h PMID38836405 PMCIDPMC11189027 DivisionProtein & Nucleic Acid Chemistry
• Initial Amino Acid:Codon Assignments and Strength of Codon:Anticodon Binding AuthorsSu M, Roberts SJ, Sutherland JD. Journal Journal of the American Chemical Society 10.1021/jacs.4c03644 (2024)
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  DOI10.1021/jacs.4c03644 PMID38676654 PMCIDPMC11082893 DivisionProtein & Nucleic Acid Chemistry
• The central dogma of biological homochirality: How does chiral information propagate in a prebiotic network? AuthorsOzturk S. F., Sasselov D. D., Sutherland J. D. Journal The Journal of Chemical Physics 159(6):061102 (2023)
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  DOI10.1063/5.0156527 PMID37551802 PMCIDPMC7615580 DivisionProtein & Nucleic Acid Chemistry
• Thiophosphate photochemistry enables prebiotic access to sugars and terpenoid precursors AuthorsRitson D. J., Sutherland J. D. Journal Nature Chemistry 15(10):1470-1477 (2023)
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  DOI10.1038/s41557-023-01251‑9 PMID37443293 PMCIDPMC10533393 DivisionProtein & Nucleic Acid Chemistry
• Origin of biological homochirality by crystallization of an RNA precursor on a magnetic surface AuthorsOzturk S. F., Liu Z., Sutherland J. D., Sasselov D. D. Journal Science Advances 9(23):eadg8274 (2023)
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  DOI10.1126/sciadv. Adg8274 PMID37285423 PMCIDPMC10246896 DivisionProtein & Nucleic Acid Chemistry
• Triplet-Encoded Prebiotic RNA Aminoacylation AuthorsSu M., Schmitt C., Liu Z., Roberts S. J., Liu K. C., Röder K., Jäschke A., Wales D. J., Sutherland J. D. Journal bioRxiv 145(29):15971-15980 (2023)
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  DOIdoi.org/10.1021/jacs.3c03931 PMID37435826 PMCIDPMC10375532 DivisionProtein & Nucleic Acid Chemistry
• Prebiotic Synthesis of N-Formylaminonitriles and Derivatives in Formamide AuthorsGreen N. J., Russell D. A., Tanner S. H., Sutherland J. D. Journal Journal of the American Chemical Society 145(19):10533-10541 (2023)
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  DOIdoi.org/10.1021/jacs.2c13306 PMID37146260 PMCIDPMC10197134 DivisionProtein & Nucleic Acid Chemistry
• Virtual Fly Brain-An interactive atlas of the Drosophila nervous system AuthorsCourt R, Costa M, Pilgrim C, Millburn G, Holmes A, McLachlan A, Larkin A, Matentzoglu N, Kir H, Parkinson H, Brown N. H. , O'Kane CJ, Armstrong J. D. , Jefferis G. S. X. E. , Osumi-Sutherland D. Journal Frontiers in Physiology 26;14:1076533 (2023)
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  DOI10.3389/fphys.2023.1076533 PMID36776967 PMCIDPMC9908962 DivisionCell Biology
• Azoles as Auxiliaries and Intermediates in Prebiotic Nucleoside Synthesis AuthorsRitson DJ, Poplawski MW, Bond AD, Sutherland JD. Journal Journal of the American Chemical Society Oct 26;144(42):19447-19455 (2022)
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  DOI10.1021/jacs.2c07774 PMID36251009 PMCIDPMC9619408 DivisionProtein & Nucleic Acid Chemistry
• Template-free assembly of functional RNAs by loop-closing ligation AuthorsWu L.F., Liu Z., Roberts S.J., Su M., Szostak J.W., Sutherland J.D. Journal Journal of the American Chemical Society 144(30):13920-13927 (2022)
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  DOI10.1021/jacs.2c05601 PMID35880790 PMCIDPMC9354263 DivisionProtein & Nucleic Acid Chemistry
• Potentially Prebiotic Synthesis of Aminoacyl-RNA via a Bridging Phosphoramidate-Ester Intermediate AuthorsRoberts S. J., Liu Z., Sutherland J. D. Journal Journal of the American Chemical Society 144(9):4254-4259 (2022)
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  DOI10.1021/jacs.2c00772 PMID35230111 PMCIDPMC9097472 DivisionProtein & Nucleic Acid Chemistry
• Prebiotic photoredox synthesis from carbon dioxide and sulfite AuthorsLiu Z., Wu L. F., Kufner C. L., Sasselov D. D., Fischer W. W., Sutherland J. D. Journal Nature Chemistry 13(11):1126-1132 (2021)
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  DOI10.1038/s41557-021-00789-w PMID34635812 PMCIDPMC7611910 DivisionProtein & Nucleic Acid Chemistry
• Timescales for Prebiotic Photochemistry Under Realistic Surface Ultraviolet Conditions AuthorsRimmer P. B., Thompson S. J., Xu J., Russell D. A., Green N. J., Ritson D. J., Sutherland J. D., Queloz D. P. Journal Astrobiology 21(9):1099-1120. 16 September 2021 (2021)
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  DOI10.1089/ast.2020.2335 PMID34152196 PMCIDPMC8570677 DivisionProtein & Nucleic Acid Chemistry
• Prebiotic Photochemical Coproduction of Purine Ribo- and Deoxyribonucleosides AuthorsXu J., Green N. J., Russell D. A., Liu Z., Sutherland J. D. Journal Journal of the American Chemical Society 143(36):14482-14486 (2021)
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  DOI10.1021/jacs.1c07403 PMID34469129 PMCIDPMC8607323 DivisionProtein & Nucleic Acid Chemistry
• Interstrand Aminoacyl Transfer in a tRNA Acceptor Stem-Overhang Mimic AuthorsWu L. F., Su M., Liu Z., Bjork S. J., Sutherland J. D. Journal Journal of the American Chemical Society 143(30):11836-11842. 4 August 2021 (2021)
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  DOI10.1021/jacs.1c05746 PMID34283595 PMCIDPMC8397310 DivisionProtein & Nucleic Acid Chemistry
• Illuminating Life's Origins: UV Photochemistry in Abiotic Synthesis of Biomolecules AuthorsGreen N. J., Xu J., Sutherland J. D. Journal Journal of the American Chemical Society 143(19):7219-7236. 19 May 2021 (2021)
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  DOI10.1021/jacs.1c01839 PMID33880920 PMCIDPMC8240947 DivisionProtein & Nucleic Acid Chemistry
• Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir‑RTP AuthorsNaydenova K., Muir K. W., Wu L. F., Zhang Z., Coscia F., Peet M. J., Castro-Hartmann P., Qian P., Sader K., Dent K., Kimanius D., Sutherland J. D., Löwe J., Barford D., Russo C. J. Journal Proceedings of the National Academy of Sciences of the United States of America 118(7):e2021946118. 16 February 2021 (2021)
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  DOI10.1073/pnas.2021946118 PMID33526596 PMCIDPMC7896311 DivisionProtein & Nucleic Acid Chemistry, Structural Studies
• pH-Dependent peptide bond formation by the selective coupling of α-amino acids in water AuthorsWu L. F., Liu Z., Sutherland J. D. Journal Chemical Communications 57(1):73-76. January 2021 (2021)
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  DOI10.1039/d0cc06042a PMID33242043 PMCIDPMC7808311 DivisionProtein & Nucleic Acid Chemistry
• Publisher Correction: Harnessing chemical energy for the activation and joining of prebiotic building blocks AuthorsLiu Z., Wu L. F., Xu J., Bonfio C., Russell D. A., Sutherland J. D. Journal Nature Chemistry 13(1):99. January 2021 (2021)
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  DOI10.1038/s41557-020-00591‑0 PMID33208896 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Photoredox chemistry in the synthesis of 2-aminoazoles implicated in prebiotic nucleic acid synthesis AuthorsLiu Z ., Wu L. F. , Bond A. D. , Sutherland J. D . Journal Chemical Communications 56(88):13563-13566. 14 November 2020 (2020)
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  DOI10.1039/d0cc05752e PMID33151212 PMCIDPMC7808312 DivisionProtein & Nucleic Acid Chemistry
• Harnessing chemical energy for the activation and joining of prebiotic building blocks AuthorsLiu Z., Wu L. F., Xu J., Bonfio C., Russell D. A., Sutherland J. D. Journal Nature Chemistry 12(11):1-6. November 2020 (2020)
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  DOI10.1038/s41557-020-00564-3 PMID33093680 PMCIDPMC7610406 DivisionProtein & Nucleic Acid Chemistry
• Selective prebiotic formation of RNA pyrimidine and DNA purine nucleosides AuthorsXu J., Chmela V., Green N. J., Russell D. A., Janicki M. J., Góra R. W., Szabla R., Bond A. D., Sutherland J. D. Journal Nature 582(7810):60-66. 4 June 2020 (2020)
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  DOI10.1038/s41586-020-2330‑9 PMID32494078 PMCIDPMC7116818 DivisionProtein & Nucleic Acid Chemistry
• Supply of phosphate to early Earth by photogeochemistry after meteoritic weathering AuthorsRitson D. J., Mojzsis S. J., Sutherland J. D. Journal Nature Geoscience 13(5):344-348. May 2020 (2020)
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  DOI10.1038/s41561-020-0556-7 PMID32395178 PMCIDPMC7213494 DivisionProtein & Nucleic Acid Chemistry
• The origin of life as a planetary phenomenon AuthorsSasselov D. D., Grotzinger J. P., Sutherland J. D. Journal Science Advances 6(6):eaax3419. 5 February 2020 (2020)
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  DOI10.1126/sciadv. Aax3419 PMID32076638 PMCIDPMC7002131 DivisionProtein & Nucleic Acid Chemistry
• Direct interplay between stereochemistry and conformational preferences in aminoacylated oligoribonucleotides AuthorsPolyansky A. A., Kreuter M., Sutherland J. D., Zagrovic B. Journal Nucleic Acids Research 47(21):11077-11089. 2 December 2019 (2019)
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  DOI10.1093/nar/gkz902 PMID31612955 PMCIDPMC6868383 DivisionProtein & Nucleic Acid Chemistry
• Provisioning the origin and early evolution of life AuthorsWu L. F., Sutherland J. D. Journal Emerging Topics in Life Sciences 3(5):459-468. November 2019 (2019)
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  DOI10.1042/etls20190011 PMID32002470 PMCIDPMC6992421 DivisionProtein & Nucleic Acid Chemistry
• Charting a course for chemistry AuthorsAspuru-Guzik A., Baik M. H., Balasubramanian S., Banerjee R., Bart S., Borduas-Dedekind N., Chang S., Chen P., Corminboeuf C., Coudert F. X., Cronin L., Crudden C., Cuk T., Doyle A. G., Fan C., Feng X., Freedman D., Furukawa S., Ghosh S., Glorius F., Jeffries-El M., Katsonis N., Li A., Linse S. S., Marchesan S., Maulide N., Milo A., Narayan A. R. H., Naumov P., Nevado C., Nyokong T., Palacin ., Reid M., Robinson C., Robinson G., Sarpong R., Schindler C., Schlau-Cohen G. S., Schmidt T. W., Sessoli R., Shao-Horn Y., Sleiman H., Sutherland J., Taylor A., Tezcan A., Tortosa M., Walsh A., Watson A. J. B., Weckhuysen B. M., Weiss E., Wilson D., Yam V. W., Yang X., Ying J. Y., Yoon T., You S. L., Zarbin A. J. G ., Zhang H. Journal Nature Chemistry 11(4):286-294. April 2019 (2019)
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  DOI10.1038/s41557-019-0236‑7 PMID30903035 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Prebiotic phosphorylation of 2-thiouridine provides either nucleotides or DNA building blocks via photoreduction AuthorsXu J., Green N. J., Gibard C., Krishnamurthy R., Sutherland J. D. Journal Nature Chemistry 11(5):457-462. 1 April 2019 (2019)
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  DOI10.1038/s41557-019-0225-x PMID30936523 PMCIDPMC6597365 DivisionProtein & Nucleic Acid Chemistry
• Length-Selective Synthesis of Acylglycerol-Phosphates through Energy-Dissipative Cycling AuthorsBonfio C., Caumes C., Duffy C. D., Patel B. H., Percivalle C., Tsanakopoulou M., Sutherland J. D. Journal Journal of the American Chemical Society 141(9):3934-3939. 6 March 2019 (2019)
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  DOI10.1021/jacs.8b12331 PMID30767518 PMCIDPMC6506141 DivisionProtein & Nucleic Acid Chemistry
• Do sulfate radicals really enable a non-enzymatic Krebs cycle precursor? AuthorsSutherland J., Ritson D. Journal Nature Ecology & Evolution 3(2):138. February 2019 (2019)
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  DOI10.1038/s41559-018-0791‑0 PMID30697001 PMCID  DivisionProtein & Nucleic Acid Chemistry
• pH-Driven RNA Strand Separation under Prebiotically Plausible Conditions AuthorsMariani A., Bonfio C., Johnson C. M., Sutherland J. D. Journal Biochemistry 57(45):6382-6386. 13 November 2018 (2018)
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  DOI10.1021/acs. Biochem.8b01080 PMID30383375 PMCIDPMC6340128 DivisionProtein & Nucleic Acid Chemistry
• Tuning the reactivity of nitriles using Cu(ii) catalysis - potentially prebiotic activation of nucleotides AuthorsLiu Z., Mariani A., Wu L., Ritson D., Folli A., Murphy D., Sutherland J. Journal Chemical Science 9(35):7053-7057. 21 September 2018 (2018)
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  DOI10.1039/c8sc02513d PMID30310625 PMCIDPMC6137443 DivisionProtein & Nucleic Acid Chemistry
• Sulfidic anion concentrations on early Earth for surficial origins-of-Life chemistry AuthorsRanjan S., Todd Z. R., Sutherland J. D., Sasselov D. D. Journal Astrobiology 18(8):1023-1040. August 2018 (2018)
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  DOI10.1089/ast.2017.1770 PMID29627997 PMCIDPMC6225604 DivisionProtein & Nucleic Acid Chemistry
• The origin of RNA precursors on exoplanets AuthorsRimmer P. B., Xu J., Thompson S. J., Gillen E., Sutherland J. D., Queloz D. Journal Science Advances 4(8):eaar3302. August 2018 (2018)
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  DOI10.1126/sciadv. Aar3302 PMID30083602 PMCIDPMC6070314 DivisionProtein & Nucleic Acid Chemistry
• A Light-Releasable Potentially Prebiotic Nucleotide Activating Agent AuthorsMariani A., Russell D. A., Javelle T., Sutherland J. D. Journal Journal of the American Chemical Society 140(28):8657-8661. 18 July 2018 (2018)
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  DOI10.1021/jacs.8b05189 PMID29965757 PMCIDPMC6152610 DivisionProtein & Nucleic Acid Chemistry
• Photochemical reductive homologation of hydrogen cyanide using sulfite and ferrocyanide AuthorsXu J. Ritson D. J., Ranjan S., Todd Z. R., Sasselov D. D., Sutherland J. D. Journal Chemical Communications 54(44):5566-5569. 4 June 2018 (2018)
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  DOI10.1039/c8cc01499j PMID29761807 PMCIDPMC5972737 DivisionProtein & Nucleic Acid Chemistry
• Mimicking the surface and prebiotic chemistry of early Earth using flow chemistry AuthorsRitson D. J., Battilocchio C., Ley S. V., Sutherland J. D. Journal Nature Communications 9(1):1821. 8 May 2018 (2018)
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  DOI10.1038/s41467-018-04147‑2 PMID29739945 PMCIDPMC5940729 DivisionProtein & Nucleic Acid Chemistry
• UV-light-driven prebiotic synthesis of iron-sulfur clusters AuthorsBonfio C., Valer L., Scintilla S., Shah S., Evans D. J., Jin L., Szostak J. W., Sasselov D. D., Sutherland J. D., Mansy S. S. Journal Nature Chemistry 9(12):1229-1234. December 2017 (2017)
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  DOI10.1038/nchem.2817 PMID29168482 PMCIDPMC5808832 DivisionProtein & Nucleic Acid Chemistry
• Cyanamide as a prebiotic phosphate activating agent - catalysis by simple 2-oxoacid salts AuthorsTsanakopoulou M., Sutherland J. D. Journal Chemical Communications 53(87):11893-11896. 18 October 2017 (2017)
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  DOI10.1039/c7cc07517k PMID29043309 PMCIDPMC5708344 DivisionProtein & Nucleic Acid Chemistry
• High Energy Radical Chemistry Formation of HCN-rich Atmospheres on early Earth AuthorsFerus M., Kubelík P., Knížek A., Pastorek A., Sutherland J., Civiš S. Journal Scientific Reports 7(1):6275. 24 July 2017 (2017)
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  DOI10.1038/s41598-017-06489-1 PMID28740207 PMCIDPMC5524942 DivisionProtein & Nucleic Acid Chemistry
• Non-Enzymatic RNA Backbone Proofreading through Energy-Dissipative Recycling AuthorsMariani A., Sutherland J. D. Journal Angewandte Chemie 56(23):6563-6566. 1 June 2017 (2017)
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  DOI10.1002/anie.201703169 PMID28467695 PMCIDPMC5488188 DivisionProtein & Nucleic Acid Chemistry
• A prebiotically plausible synthesis of pyrimidine β-ribonucleosides and their phosphate derivatives involving photoanomerization AuthorsXu J., Tsanakopoulou M., Magnani C. J., Szabla R., Šponer J. E., Šponer J., Góra R. W., Sutherland J. D. Journal Nature Chemistry 9(4):303-309. April 2017 (2017)
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  DOI10.1038/nchem.2664 PMID28338689 PMCIDPMC5576532 DivisionProtein & Nucleic Acid Chemistry
• A new and potentially prebiotic α-cytidine derivative AuthorsTsanakopoulou M., Xu J., Bond A. D., Sutherland J. D. Journal Chemical Communications 53(23):3327-3329. 21 March 2017 (2017)
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  DOI10.1039/c7cc00693d PMID28229150 PMCIDPMC5510716 DivisionProtein & Nucleic Acid Chemistry
• Opinion: Studies on the origin of life — the end of the beginning AuthorsSutherland J. D. Journal Nature Reviews Chemistry 1: 18 January 2017 (2017)
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  DOI10.1038/s41570-016‑0012 PMID  PMCID  DivisionProtein & Nucleic Acid Chemistry
• Thiophosphate – A Versatile Prebiotic Reagent? AuthorsRitson D. J., Xu J., Sutherland J. D. Journal Synlett 28(01): 64-67. January 2017 (2017)
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  DOI10.1055/s-0036‑1589414 PMID  PMCID  DivisionProtein & Nucleic Acid Chemistry
• Mixed Anhydride Intermediates in the Reaction of 5(4H)-Oxazolones with Phosphate Esters and Nucleotides AuthorsLiu Z., Rigger L., Rossi J. C., Sutherland J. D., Pascal R. Journal Chemistry 22(42):14940-14949. 10 October 2016 (2016)
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  DOI10.1002/chem.201602697 PMID27534830 PMCIDPMC5074369 DivisionProtein & Nucleic Acid Chemistry
• The Origin of Life-Out of the Blue AuthorsSutherland J. D. Journal Angewandte Chemie 55(1):104-121. 4 January 2016 (2016)
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  DOI10.1002/anie.201506585 PMID26510485 PMCID  DivisionProtein & Nucleic Acid Chemistry
• A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells AuthorsCook P. C., Owen H., Deaton A. M., Borger J. G., Brown S. L., Clouaire T., Jones G. R., Jones L. H., Lundie R. J., Marley A. K., Morrison V. L., Phythian-Adams A. T., Wachter E., Webb L. M., Sutherland T. E., Thomas G. D., Grainger J. R., Selfridge J., McKenzie A. N., Allen J. E., Fagerholm S. C., Maizels R. M., Ivens A. C., Bird A., MacDonald A. S. Journal Nature Communications 6:6920. 24 April 2015 (2015)
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  DOI10.1038/ncomms7920 PMID25908537 PMCIDPMC4413429 DivisionProtein & Nucleic Acid Chemistry
• Common origins of RNA, protein and lipid precursors in a cyanosulfidic protometabolism. AuthorsPatel B. H., Percivalle C., Ritson D. J. Duffy C. D., Sutherland J. D. Journal Nature Chemistry 7(4):301-307. April 2015 (2015)
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  DOI10.1038/nchem.2202 PMID25803468 PMCIDPMC4568310 DivisionProtein & Nucleic Acid Chemistry
• Self-assembly of phosphate amphiphiles in mixtures of prebiotically plausible surfactants AuthorsAlbertsen A. N., Duffy C. D., Sutherland J. D., Monnard P. A. Journal Astrobiology 14(6):462-472. 1 June 2014 (2014)
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  DOI10.1089/ast.2013.1111 PMID24885934 PMCIDPMC4060816 DivisionProtein & Nucleic Acid Chemistry
• Conversion of biosynthetic precursors of RNA to those of DNA by photoredox chemistry AuthorsRitson D. J., Sutherland J. D. Journal Journal of Molecular Evolution 78(5):245-250. May 2014 (2014)
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  DOI10.1007/s00239-014-9617-0 PMID24736972 PMCIDPMC4037592 DivisionProtein & Nucleic Acid Chemistry
• Solid-phase synthesis and hybrization behavior of partially 2'/3'-O-acetylated RNA oligonucleotides AuthorsXu J., Duffy C. D., Chan C. K., Sutherland J. D. Journal Journal of Organic Chemistry 79(8):3311-3326. 18 April 2014 (2014)
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  DOI10.1021/jo5002824 PMID24666354 PMCIDPMC4323357 DivisionProtein & Nucleic Acid Chemistry
• Towards an evolutionary theory of the origin of life based on kinetics and thermodynamics AuthorsPascal R., Pross A., Sutherland J. D. Journal Open Biology 3(11):130156. November 2013 (2013)
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  DOI10.1098/rsob.130156 PMID24196781 PMCIDPMC3843823 DivisionProtein & Nucleic Acid Chemistry
• Synthesis of aldehydic ribonucleotide and amino acid precursors by photoredox chemistry AuthorsRitson D. J., Sutherland J. D. Journal Angewandte Chemie (International ed. in English) 52(22):5845-5847. 27 May 2013 (2013)
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  DOI10.1002/anie.201300321 PMID23610046 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Prebiotically plausible oligoribonucleotide ligation facilitated by chemoselective acetylation AuthorsBowler F. R., Chan C. K., Duffy C. D., Gerland B., Islam S., Powner M. W., Sutherland J. D., Xu J. Journal Nature Chemistry 5(5):383-389. May 2013 (2013)
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  DOI10.1038/nchem.1626 PMID23609088 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Detection of potential TNA and RNA nucleoside precursors in a prebiotic mixture by pure shift diffusion-ordered NMR spectroscopy AuthorsIslam S., Aguilar J. A., Powner M. W., Nilsson M., Morris G. A., Sutherland J. D. Journal Chemistry 19(14):4586-4595. 2 April 2013 (2013)
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  DOI10.1002/chem.201202649 PMID23371787 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Prebiotic synthesis of simple sugars by photoredox systems chemistry AuthorsRitson D., Sutherland J. D. Journal Nature Chemistry 4(11):895-899. November 2012 (2012)
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  DOI10.1038/nchem.1467 PMID23089863 PMCIDPMC3589744 DivisionProtein & Nucleic Acid Chemistry
• A strategy for building neuroanatomy ontologies AuthorsOsumi-Sutherland D., Reeve S., Mungall C. J., Neuhaus F., Ruttenberg A., Jefferis G. S. X. E. , Armstrong J. D. Journal Bioinformatics 28(9):1262-1269. 1 May 2012 (2012)
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  DOI10.1093/bioinformatics/bts113 PMID22402613 PMCID  DivisionNeurobiology
• Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing AuthorsPradeepa M. M., Sutherland H. G., Ule J., Grimes G. R., Bickmore W. A. Journal PLoS Genetics 8(5):e1002717. May 2012 (2012)
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  DOI10.1371/journal.pgen.1002717 PMID22615581 PMCIDPMC3355077 DivisionStructural Studies
• The chemical origins of life and its early evolution: an introduction AuthorsLilley D. M., Sutherland J. Journal Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 366(1580):2853-2856. 27 October 2011 (2011)
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  DOI10.1098/rstb.2011.0133 PMID21930575 PMCIDPMC3158915 DivisionProtein & Nucleic Acid Chemistry
• The origins of nucleotides AuthorsPowner, M. W., Sutherland, J. D., Szostak, J. W. Journal Synlett Issue 14: 1956-1964. September 2011 (2011)
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  DOI10.1055/s-0030‑1261177 PMID  PMCID  DivisionProtein & Nucleic Acid Chemistry
• Chemoselective multicomponent one-pot assembly of purine precursors in water AuthorsPowner M. W., Sutherland J. D., Szostak J. W. Journal Journal of the American Chemical Society 132(46):16677-16688. 24 November 2010 (2010)
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  DOI10.1021/ja108197s PMID21043502 PMCIDPMC2984373 DivisionProtein & Nucleic Acid Chemistry
• Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance AuthorsJose R. Bayascas, Stephan Wullschleger, Kei Sakamoto, Juan M. García-Martínez, Carol Clacher, David Komander, Daan M. F. van Aalten, Krishna M. Boini, Florian Lang, Christopher Lipina, Lisa Logie, Calum Sutherland, John A. Chudek, Janna A. van Diepen, Peter J. Voshol, John M. Lucocq, Dario R. Alessi Journal Molecular and Cellular Biology 28 (10): 3258-3272 (2008)
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  DOI  PMID18347057 PMCIDPMC2423167 Division 
• The Emery-Dreifuss muscular dystrophy associated-protein emerin is phosphorylated on serine 49 by protein kinase A AuthorsRhys C. Roberts, Andrew J. Sutherland-Smith, Matthew A. Wheeler, Ole Norregaard Jensen, Lindsay J. Emerson, Ioannis I. Spiliotis, Christopher G. Tate, John Kendrick-Jones, Juliet A. Ellis Journal FEBS Journal 273: 4562-4575 (2006) (2006)
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• An open or closed case for the conformation of calponin homology domains on F‑actin? AuthorsWilliam Lehman, Roger Craig, John Kendrick-Jones, Andrew J. Sutherland‑Smith Journal Journal of Muscle Research and Cell Motility 25(4-5):351-358 (2004) (2004)
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  DOI10.1007/s10974-004-0690‑7 PMID15548864 PMCID  Division 
• An atomic model for actin binding by the CH domains and spectrin-repeat modules of utrophin and dystrophin AuthorsAndrew J. Sutherland-Smith, Carolyn A. Moores, Fiona L. M. Norwood, Victoria Hatch, Roger Craig, John Kendrick-Jones, William Lehman Journal Journal of Molecular Biology 329: 15-33 (2003) (2003)
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  DOI  PMID  PMCID  Division 
• Localized mutations in the gene encoding the cytoskeletal protein filamin A cause diverse malformations in humans AuthorsStephen P. Robertson, Stephen R. F. Twigg, Andrew J. Sutherland-Smith, Valerie Biancalana, Robert J. Gorlin, Denise Horn, Susan J. Kenwrick, Chong A. Kim, Eva Morava, Ruth Newbury-Ecob, Karen H. Orstavik, Oliver W. J. Quarrell, Charles E. Schwartz, Deborah J. Shears, Mohnish Suri, John Kendrick-Jones, The OPD-spectrum Disorders Clinical Collaborative Group, Andrew O M. Wilkie Journal Nature Genetics 33: 487-491 (2003) (2003)
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• Mutation of the GABAA receptor M1 transmembrane proline increases GABA affinity and reduces barbiturate enhancement AuthorsGreenfield Jr. L. J., Zaman S. H., Sutherland M. L., Lummis S. C. R., Niemeyer M-I., Barnard E. A., Macdonald R. L. Journal Neuropharmacology 42(4):502-521. March 2002 (2002)
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  DOI10.1016/s0028-3908(01)00196-4 PMID11955521 PMCID  DivisionNeurobiology
• The structure of the N-terminal actin-binding domain of human dystrophin and how mutations in this domain may cause Duchenne or Becker muscular dystrophy AuthorsNorwood F. L. M., Sutherland-Smith A. J., Keep N. H., Kendrick-Jones J. Journal Structure 8(5):481-491 (2000) (2000)
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  DOI10.1016/s0969-2126(00)00132‑5 PMID10801490 PMCID  DivisionStructural Studies
• The effect of two actin depolymerizing factors (ADF/cofilins) on actin filament turnover : pH sensitivity of F-actin binding by human ADF but not Acanthamoeba actophorin AuthorsSutherland K. Maciver, Brian J. Pope, Sue Whytock, Alan G. Weeds Journal European Journal of Biochemistry 256 : 388-397 (1998) (1998 )
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• Localization of the calcium-sensitive actin monomer binding site in gelsolin to segment 4 and identification of calcium binding sites AuthorsBrian Pope, Sutherland Maciver, Alan Weeds Journal Biochemistry 34: 1583-1588 (1995) (1995)
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• An actin-related protein from Dictyostelium discoideum is developmentally regulated and associated with mitochondria AuthorsIrene Murgia, Sutherland K. Maciver, Piero Morandini Journal FEBS Letters 360: 235-241 (1995) (1995)
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• F-actin capping proteins AuthorsAlan Weeds, Sutherland Maciver Journal Current Opinion in Cell Biology 5: 63-69 (1993) (1993)
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