Published Research

Found 213 results for Stewart.

• De novo design of miniproteins targeting GPCRs AuthorsMuratspahić E., Feldman D., Kim D. E., Qu X., Bratovianu A. M., Rivera-Sánchez P., Voss J. H., Hertz E. P. T., Jeppesen M., Dimitri F., Sakamoto K., Nallathambi A., Peceli P., Cao J., Cary B. P., Belousoff M. J., Keov P., Trinh P. N. H., Chen Q., Ren Y., Fine J., Mishra S., Dalal A., Sinha S., Banerjee R., Ganguly M., Karuppusamy K. V., Sappington I., Schlichthaerle T., Zhang J. Z., Pillai A., Coventry B., Mihaljević L., Bauer M., Torres S. V., Motmaen A., Lee G. R., Tran L., Wang X., Goreshnik I., Vafeados D. K., Svendsen J. E., Hosseinzadeh P., Lindegaard N., Brandt M., Waltenspühl Y., Deibler K., Deweid L., Bennett A., Schöppe J., Dong T., Yan X., Oostdyk L., Cao W., Anantharaman L., Weisser J. J., Bastlund J. F., Bundgaard C., Asuni A. A., English J. G., Stewart L., Halloran L., Spangler J. B., Lieber A., Shukla A. K., Sexton P. M., Roth B. L., Krumm B. E., Wootten D., Tate C. G., Norn C., Baker D. Journal Nature (2026)
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  DOI10.1038/s41586-026-10656-8 PMID42168559 PMCID  DivisionStructural Studies
• The replication function of rabies virus P protein Is regulated by a novel phosphorylation site in the N-terminal N protein-binding region AuthorsTudhope E. Donnelly C.M., Sethi A., David C., Williamson N., Stewart M., Forwood J.K., Gooley P.R., Moseley G.W. Journal Viruses 17(8):1075 (2025)
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  DOI10.3390/v17081075 PMID40872789 PMCIDPMC12390708 DivisionStructural Studies
• From transcription to export: mRNA's winding path to the cytoplasm AuthorsStewart M. Journal Trends in Biochemical Sciences :S0968-0004(25)00134-3 (2025)
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  DOI10.1016/j.tibs.2025.06.004 PMID40670258 PMCID  DivisionStructural Studies
• Multifocal, multiphenotypic tumours arising from an MTOR mutation acquired in early embryogenesis AuthorsPacyna C. N., Anandapadamanaban M., Loudon K. W., Hay I. M., Perisic O., Li R., Byrne M., Allen L., Roberts K., Hooks Y., Warren A. Y., Stewart G. D., Clatworthy M. R., Teichmann S. A., Behjati S., Campbell P. J., Williams R. L., Mitchell T. J. Journal Oncogene 43(44):3268-3276 (2024)
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  DOI10.1038/s41388-024-03137‑7 PMID39271965 PMCIDPMC11518995 DivisionProtein & Nucleic Acid Chemistry, University
• Identification of a core transcriptional program driving the human renal mesenchymal-to-epithelial transition AuthorsNg-Blichfeldt JP, Stewart BJ, Clatworthy MR, Williams JM, Röper K. Journal Developmental Cell 59(5):595-612.e8 (2024)
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  DOI10.1016/j. devcel.2024.01.011 PMID38340720 PMCIDPMC7616043 DivisionCell Biology
• Structural Determination of the Australian Bat Lyssavirus Nucleoprotein and Phosphoprotein Complex AuthorsDonnelly C. M., Stewart M., Roby J. A., Sundaramoorthy V., Forwood J. K. Journal Viruses 16(1):33 (2023)
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  DOI10.3390/v16010033 PMID38229694 PMCIDPMC7615531 DivisionStructural Studies
• Cephalopod-omics: Emerging Fields and Technologies in Cephalopod Biology AuthorsBaden T., Briseño J., Coffing G., Cohen-Bodénès S., Courtney A., Dickerson D., Dölen G., Fiorito G., Gestal C., Gustafson T., Heath-Heckman E., Hua Q., Imperadore P., Kimbara R., Król M., Lajbner Z., Lichilín N., Macchi F., McCoy M. J., Nishiguchi M. K., Nyholm S. V., Otjacques E., Pérez-Ferrer P. A., Ponte G., Pungor J. R., Rogers T. F., Rosenthal J. J. C., Rouressol L., Rubas N., Sanchez G., Santos C. P., Schultz D. T., Seuntjens E., Songco-Casey J. O., Stewart I. E., Styfhals R., Tuanapaya S., Vijayan N., Weissenbacher A., Zifcakova L., Schulz G., Weertman W., Simakov O., Albertin C. Journal Integrative and Comparative Biology icad087 volume 0, pp. 1–14 (2023)
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  DOI10.1093/icb/icad087 PMID37370232 PMCIDPMC10755191 DivisionNeurobiology
• Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2 AuthorsGaynor K. U., Vaysburd M., Harman M. A. J., Albecka A., Jeffrey P., Beswick P., Papa G., Chen L., Mallery D., McGuinness B., Van Rietschoten K., Stanway S., Brear P., Lulla A, Ciazynska K., Chang V. T., Sharp J., Neary M., Box H., Herriott J., Kijak E., Tatham L., Bentley E. G., Sharma P., Kirby A., Han X., Stewart J. P., Owen A., Briggs J A. G., Hyvönen M., Skynner M. J., James L. C. Journal Nature Communications 14(1):3583 (2023)
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  DOI10.1038/s41467-023-39158-1 PMID37328472 PMCIDPMC10275983 DivisionProtein & Nucleic Acid Chemistry
• De novo design of modular peptide-binding proteins by superhelical matching AuthorsWu K., Bai H., Chang Y. T., Redler R., McNally K. E., Sheffler W., Brunette T. J., Hicks D. R., Morgan T. E., Stevens T. J., Broerman A., Goreshnik I., DeWitt M., Chow C. M., Shen Y., Stewart L., Derivery E., Silva D. A, Bhabha G., Ekiert D. C, Baker D. Journal Nature 616(7957):581-589 (2023)
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  DOI 10.1038/s41586-023-05909‑9 PMID37020023 PMCIDPMC10115654 DivisionCell Biology
• MERS-CoV ORF4b employs an unusual binding mechanism to target IMPα and block innate immunity AuthorsMunasinghe T. S., Edwards M. R., Tsimbalyuk S., Vogel O. A., Smith K. M., Stewart M., Foster J. K., Bosence L. A., Aragão D., Roby J. A., Basler C. F., Forwood J. K. Journal Nature Communications 13(1):1604 (2022)
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  DOI10.1038/s41467-022-28851‑2 PMID35338144 PMCIDPMC8956657 DivisionStructural Studies
• Function of the Nuclear Transport Machinery in Maintaining the Distinctive Compositions of the Nucleus and Cytoplasm AuthorsStewart M. Journal International Journal of Molecular Sciences 23(5):2578 (2022)
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  DOI10.3390/ijms23052578 PMID35269721 PMCIDPMC8910404 DivisionStructural Studies
• Helical ordering of envelope-associated proteins and glycoproteins in respiratory syncytial virus AuthorsConley M. J., Short J. M., Burns A. M., Streetley J., Hutchings J., Bakker S. E., Power B. J., Jaffery H., Haney J., Zanetti G., Murcia P. R., Stewart M., Fearns R., Vijayakrishnan S., Bhella D. Journal EMBO Journal 41(3):e109728 (2022)
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  DOI10.15252/embj.2021109728 PMID34935163 PMCIDPMC8804925 DivisionStructural Studies
• Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair AuthorsSanchez-Bailon M. P., Choi S. Y., Dufficy E. R., Sharma K., McNee G. S., Gunnell E., Chiang K., Sahay D., Maslen S., Stewart G. S., Skehel J. M., Dreveny I., Davies C. C. Journal Nature Communications 12(1):6313 (2021)
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  DOI10.1038/s41467-021-26413‑6 PMID34728620 PMCIDPMC8564520 DivisionCell Biology
• Single-dose immunisation with a multimerised SARS-CoV-2 receptor binding domain (RBD) induces an enhanced and protective response in mice AuthorsRalf Salzer, Jordan J. Clark, Marina Vaysburd, Veronica T. Chang, Anna Albecka, Leo Kiss, Parul Sharma, Andres Gonzalez Llamazares, Anja Kipar, Julian A. Hiscox, Andrew Owen, A. Radu Aricescu, James P. Stewart, Leo C. James, Jan Löwe Journal FEBS Letters 595(18):2323-2340 (2021)
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  DOI10.1002/1873-3468.14171 PMID34331769 PMCIDPMC8426897 DivisionNeurobiology, Protein & Nucleic Acid Chemistry, Structural Studies
• Translation stress and collided ribosomes are co-activators of cGAS AuthorsWan L., Juszkiewicz S., Blears D., Bajpe P. K., Han Z., Faull P., Mitter R., Stewart A., Snijders A. P., Hegde R. S., Svejstrup J. Q. Journal Molecular Cell 81(13):2808-2822.e10. 1 July 2021 (2021)
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  DOI10.1016/j.molcel.2021.05.018 PMID34111399 PMCIDPMC8260207 DivisionCell Biology
• Structural basis for nuclear import selectivity of pioneer transcription factor SOX2 AuthorsJagga B., Edwards M., Pagin M., Wagstaff K. M., Aragão D., Roman N., Nanson J. D., Raidal S. R., Dominado N., Stewart M., Jans D. A., Hime G. R., Nicolis S. K., Basler C. F., Forwood J. K. Journal Nature Communications 12(1):28. 4 January 2021 (2021)
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  DOI10.1038/s41467-020-20194-0 PMID33397924 PMCIDPMC7782513 DivisionStructural Studies
• Dissecting the Roles of Cse1 and Nup2 in Classical NLS-Cargo Release in vivo AuthorsLange A., Fasken M. B., Stewart M., Corbett A. H. Journal Traffic 21(10):622-635. October 2020 (2020)
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  DOI10.1111/tra.12759 PMID32734712 PMCIDPMC7891619 DivisionStructural Studies
• Distinct effects on mRNA export factor GANP underlie neurological disease phenotypes and alter gene expression depending on intron content AuthorsWoldegebriel R., Kvist J., Andersson N., Õunap K., Reinson K., Wojcik M. H., Bijlsma E. K., Hoffer M. J. V., Ryan M. M., Stark Z., Walsh M., Cuppen I., van den Boogaard M. H., Bharucha-Goebel D., Donkervoort S., Winchester S., Zori R., Bönnemann C. G., Maroofian R., O'Connor E. Houlden H., Zhao F., Carpén O., White M., Sreedharan J., Stewart M., Ylikallio E., Tyynismaa H. Journal Human Molecular Genetics 29(9):1426-1439. 19 March 2020 (2020)
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  DOI10.1093/hmg/ddaa051 PMID32202298 PMCIDPMC7297229 DivisionStructural Studies
• Anti-commensal IgG drives intestinal inflammation and type 17 immunity in ulcerative colitis AuthorsCastro-Dopico T., Dennison T. W., Ferdinand J. R., Mathews R. J., Fleming A., Clift D., Stewart B. J., Jing C., Strongili K., Labzin L. I., Monk E. J. M., Saeb-Parsy K., Bryant C. E., Clare S., Parkes M., Clatworthy M. R. Journal Immunity 50(4):1099-1114.e10. 12 March 2019 (2019)
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  DOI10.1016/j.immuni.2019.02.006 PMID30876876 PMCIDPMC6477154 DivisionProtein & Nucleic Acid Chemistry
• Structure-function relationships in the Nab2 polyadenosine-RNA binding Zn finger protein family AuthorsFasken M. B., Corbett A. H., Stewart M. Journal Protein Science 28(3):513-523. March 2019 (2019)
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  DOI10.1002/pro.3565 PMID30578643 PMCIDPMC6371209 DivisionStructural Studies
• Polyadenylation and nuclear export of mRNAs AuthorsStewart M. Journal Journal of Biological Chemistry 294(9):2977-2987. 1 March 2019 (2019)
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  DOI10.1074/jbc. REV118.005594 PMID30683695 PMCIDPMC6398137 DivisionStructural Studies
• Structure and Function of the TREX-2 Complex AuthorsStewart M. Journal Sub-cellular Biochemistry 93:461-470. January 2019 (2019)
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  DOI10.1007/978-3-030-28151-9_15 PMID31939161 PMCID  DivisionStructural Studies
• Molecular basis of USP7 inhibition by selective small-molecule inhibitors AuthorsTurnbull A. P., Ioannidis S., Krajewski W. W., Pinto-Fernandez A., Heride C., Martin A. C. L., Tonkin L. M., Townsend E. C., Buker S. M., Lancia D. R., Caravella J. A., Toms A. V., Charlton T. M., Lahdenranta J., Wilker E., Follows B. C., Evans N. J., Stead L., Alli C., Zarayskiy V. V., Talbot A. C., Buckmelter A. J., Wang M., McKinnon C. L., Saab F., McGouran J. F., Century H., Gersch M., Pittman M. S., Marshall C. G., Raynham T. M., Simcox M., Stewart L. M. D., McLoughlin S. B., Escobedo J. A., Bair K. W., Dinsmore C. J., Hammonds T. R., Kim S., Urbé S., Clague M. J., Kessler B. M., Komander D. Journal Nature 550(7677):481-486. 26 October 2017 (2017)
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  DOI10.1038/nature24451 PMID29045389 PMCIDPMC6029662 DivisionProtein & Nucleic Acid Chemistry
• Structure of the Sac3 RNA-binding M-region in the Saccharomyces cerevisiae TREX-2 complex AuthorsGordon J. M., Aibara S., Stewart M. Journal Nucleic Acids Research 45(9):5577-5585. 19 May 2017 (2017)
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  DOI10.1093/nar/gkx158 PMID28334829 PMCIDPMC5435946 DivisionStructural Studies
• PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination AuthorsClarke T. L., Sanchez-Bailon M. P., Chiang K., Reynolds J. J., Herrero-Ruiz J., Bandeiras T. M., Matias P. M., Maslen S. L., Skehel J. M., Stewart G. S., Davies C. C. Journal Molecular Cell 65(5):900-916.e7. 2 March 2017 (2017)
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  DOI10.1016/j.molcel.2017.01.019 PMID28238654 PMCIDPMC5344794 DivisionCell Biology
• Structural basis for the dimerization of Nab2 generated by RNA binding provides insight into its contribution to both poly(A) tail length determination and transcript compaction in Saccharomyces cerevisiae AuthorsAibara S., Gordon J. M., Riesterer A. S., McLaughlin S. H., Stewart M. Journal Nucleic Acids Research 45(3):1529-1538. February 2017 (2017)
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  DOI10.1093/nar/gkw1224 PMID28180315 PMCIDPMC5388407 DivisionStructural Studies
• Development of Cell-Permeable, Non-Helical Constrained Peptides to Target a Key Protein-Protein Interaction in Ovarian Cancer AuthorsWiedmann M. M., Tan Y. S., Wu Y., Aibara S., Xu W., Sore H. F., Verma C. S., Itzhaki L., Stewart M., Brenton J. D., Spring D. R. Journal Angewandte Chemie 56(2):524-529 (2017)
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  DOI10.1002/anie.201609427 PMID27918136 PMCIDPMC5291322 DivisionStructural Studies
• Structural and calorimetric studies demonstrate that the Hepatocyte Nuclear Factor1β (HNF1β) transcription factor is imported into the nucleus via a monopartite NLS sequence AuthorsWiedmann M. M., Aibara S., Spring D. R., Stewart M., Brenton J. D. Journal Journal of Structural Biology 195(3):273-281. September 2016 (2016)
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  DOI10.1016/j.jsb.2016.06.018 PMID27346421 PMCIDPMC4991853 DivisionStructural Studies
• The Sac3 TPR-like region in the Saccharomyces cerevisiae TREX-2 complex is more extensive but independent of the CID region AuthorsAibara S., Bai X. C., Stewart M. Journal Journal of Structural Biology 195(3):316-324 September 2016 (2016)
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  DOI10.1016/j.jsb.2016.07.007 PMID27422657 PMCIDPMC4991852 DivisionStructural Studies
• Structural Biology and Regulation of Protein Import into the Nucleus AuthorsChristie M., Chang C. W., Róna G., Smith K. M., Stewart A. G., Takeda A. A., Fontes M. R., Stewart M., Vértessy B. G., Forwood J. K., Kobe B. Journal Journal of Molecular Biology 428(10 Pt A):2060-2090. 22 May 2016 (2016)
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  DOI10.1016/j.jmb.2015.10.023 PMID26523678 PMCID  DivisionStructural Studies
• A physical model describing the interaction of nuclear transport receptors with FG nucleoporin domain assemblies AuthorsZahn R., Osmanović D., Ehret S., Araya Callis C., Frey S., Stewart M., You C., Görlich D., Hoogenboom B. W., Richter R. P. Journal ELife 5:e14119. 8 April 2016 (2016)
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  DOI10.7554/eLife.14119 PMID27058170 PMCIDPMC4874776 DivisionStructural Studies
• 1.25 A resolution structure of an RNA 20-mer that binds to the TREX2 complex. AuthorsValkov E., Stewart M. Journal Acta Crystallographica. Section F, Structural Biology Communications 71(Pt 10):1318-1321. 1 October 2015 (2015)
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  DOI10.1107/S2053230X1501643X PMID26457524 PMCIDPMC4601597 DivisionStructural Studies
• Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2 AuthorsDimitrova L., Valkov E., Aibara S., Flemming D., McLaughlin S. H., Hurt E., Stewart M. Journal Structure 23(7):1246-1257. 7 July 2015 (2015)
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  DOI10.1016/j.str.2015.05.002 PMID26051714 PMCIDPMC4509546 DivisionStructural Studies
• Structural characterization of the principal mRNA-export factor Mex67-Mtr2 from Chaetomium thermophilum AuthorsAibara S., Valkov E., Lamers M. H., Dimitrova L., Hurt E., Stewart M. Journal Acta Crystallographica. Section F, Structural Biology Communications 71(Pt 7):876-888. 1 July 2015 (2015)
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  DOI10.1107/S2053230X15008766 PMID26144233 PMCIDPMC4498709 DivisionStructural Studies
• Selective Targeting of the TPX2 Site of Importin-α Using Fragment-Based Ligand Design AuthorsHolvey R. S., Valkov E., Neal D., Stewart M., Abell C. Journal ChemMedChem 10(7):1232-1239. July 2015 (2015)
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  DOI10.1002/cmdc.201500014 PMID25899172 PMCIDPMC4515083 DivisionStructural Studies
• The principal mRNA nuclear export factor NXF1:NXT1 forms a symmetric binding platform that facilitates export of retroviral CTE‑RNA. AuthorsAibara S., Katahira J., Valkov E., Stewart M. Journal Nucleic Acids Research 43(3):1883-1893. 18 February 2015 (2015)
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  DOI10.1093/nar/gkv032 PMID25628361 PMCIDPMC4330390 DivisionStructural Studies
• Domain organization within the nuclear export factor Mex67:Mtr2 generates an extended mRNA binding surface. AuthorsAibara S., Valkov E., Lamers M., Stewart M. Journal Nucleic Acids Research 43(3):1927-1936. 18 February 2015 (2015)
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  DOI10.1093/nar/gkv030 PMID25618852 PMCIDPMC4330389 DivisionStructural Studies
• Promiscuous Binding of Karyopherinβ1 Modulates FG Nucleoporin Barrier Function and Expedites NTF2 Transport Kinetics. AuthorsWagner R. S., Kapinos L. E., Marshall N. J., Stewart M., Lim R. Y. Journal Biophysical Journal 108(4):918-927. 17 February 2015 (2015)
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  DOI10.1016/j. Bpj.2014.12.041 PMID25692596 PMCIDPMC4336380 DivisionStructural Studies
• Structural basis for Pan3 binding to Pan2 and its function in mRNA recruitment and deadenylation AuthorsWolf J., Valkov E., Allen M. D., Meineke B., Gordiyenko Y., McLaughlin S. H., Olsen T. M., Robinson C. V., Bycroft M., Stewart M., Passmore L. A. Journal EMBO Journal 33(14):1514-1526. 17 July 2014 (2014)
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  DOI10.15252/embj.201488373 PMID24872509 PMCIDPMC4158885 DivisionStructural Studies
• Structural basis for binding the TREX2 complex to nuclear pores, GAL1 localisation and mRNA export AuthorsJani D., Valkov E., Stewart M. Journal Nucleic Acids Research 42(10):6686-6697. 1 June 2014 (2014)
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  DOI10.1093/nar/gku252 PMID24705649 PMCIDPMC4041426 DivisionStructural Studies
• Selective nuclear export of specific classes of mRNA from mammalian nuclei is promoted by GANP AuthorsWickramasinghe V. O., Andrews R., Ellis P., Langford C, Gurdon J. B., Stewart M., Venkitaraman A. R., Laskey R. A. Journal Nucleic Acids Research 42(8):5059-5071. April 2014 (2014)
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  DOI10.1093/nar/gku095 PMID24510098 PMCIDPMC4005691 DivisionStructural Studies
• Structural basis for the molecular recognition of polyadenosine RNA by Nab2 Zn fingers AuthorsKuhlmann S. I., Valkov E., Stewart M. Journal Nucleic Acids Research 42(1):672-680. January 2014 (2014)
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  DOI10.1093/nar/gkt876 PMID24071581 PMCIDPMC3874189 DivisionStructural Studies
• Choreography of importin-α/CAS complex assembly and disassembly at nuclear pores AuthorsSun C., Fu G., Ciziene D., Stewart M., Musser S. M. Journal Proceedings of the National Academy of Sciences, USA 110(17):E1584-93. 23 April 2013 (2013)
  Details

  DOI10.1073/pnas.1220610110 PMID23569239 PMCID  DivisionStructural Studies
• Structural biology of the PCI-protein fold AuthorsEllisdon A. M., Stewart M. Journal Bioarchitecture 2(4):118-123. 1 July 2012 (2012)
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  DOI10.4161/bioa.21131 PMID22960705 PMCIDPMC3675071 DivisionStructural Studies
• Structural basis for polyadenosine-RNA binding by Nab2 Zn fingers and its function in mRNA nuclear export AuthorsBrockmann C., Soucek S., Kuhlmann S. I., Mills-Lujan K., Kelly S. M., Yang J. C., Iglesias N., Stutz F., Corbett A. H., Neuhaus D., Stewart M. Journal Structure 20(6):1007-1018. 6 June 2012 (2012)
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  DOI10.1016/j.str.2012.03.011 PMID22560733 PMCIDPMC3384006 DivisionStructural Studies
• Structural basis for the assembly and disassembly of mRNA nuclear export complexes AuthorsValkov E., Dean J. C., Jani D., Kuhlmann S. I., Stewart M. Journal Biochimica et Biophysica Acta 1819(6):578-592. June 2012 (2012)
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  DOI10.1016/j. Bbagrm.2012.02.017 PMID22406340 PMCID  DivisionStructural Studies
• Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export AuthorsJani D., Lutz S., Hurt E., Laskey R. A., Stewart M., Wickramasinghe V. O. Journal Nucleic Acids Research 40(10):4562-4573. May 2012 (2012)
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  DOI10.1093/nar/gks059 PMID22307388 PMCIDPMC3378895 DivisionStructural Studies
• Structural basis for the assembly and nucleic acid binding of the TREX-2 transcription-export complex AuthorsEllisdon A. M., Dimitrova L., Hurt E., Stewart M. Journal Nature Structural & Molecular Biology 19(3):328-336. March 2012 (2012)
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  DOI10.1038/nsmb.2235 PMID22343721 PMCIDPMC3303126 DivisionStructural Studies
• Tilt-pair analysis of images from a range of different specimens in single-particle electron cryomicroscopy AuthorsHenderson R., Chen S., Chen J. Z., Grigorieff N., Passmore L. A., Ciccarelli L., Rubinstein J. L., Crowther R. A., Stewart P. L., Rosenthal P. B. Journal Journal of Molecular Biology 413(5):1028-1046. 11 November 2011 (2011)
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  DOI10.1016/j.jmb.2011.09.008 PMID21939668 PMCIDPMC3220764 DivisionStructural Studies
• Reconstitution of amoeboid motility in vitro identifies a motor-independent mechanism for cell body retraction AuthorsShimabukuro K., Noda N., Stewart M., Roberts T. M. Journal Current Biology 21(20):1727-1731. 25 October 2011 (2011)
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  DOI10.1016/j. Cub.2011.08.047 PMID22000106 PMCIDPMC3210573 DivisionStructural Studies
• Electrostatic interactions involving the extreme C terminus of nuclear export factor CRM1 modulate its affinity for cargo AuthorsFox A. M., Ciziene D., McLaughlin S. H., Stewart M. Journal Journal of Biological Chemistry 286(33):29325-35. 19 August 2011 (2011)
  Details

  DOI10.1074/jbc. M111.245092 PMID21708948 PMCIDPMC3190738 DivisionStructural Studies, Protein & Nucleic Acid Chemistry
• Nuclear export of mRNA AuthorsStewart M. Journal Trends in Biochemical Sciences 35(11):609-617. 1 November 2010 (2010)
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  DOI10.1016/j.tibs.2010.07.001 PMID20719516 PMCID  DivisionStructural Studies
• Quantitative structural analysis of importin-β flexibility: paradigm for solenoid protein structures AuthorsForwood J. K., Lange A., Zachariae U., Marfori M., Preast C., Grubmüller H., Stewart M., Corbett A. H., Kobe B. Journal Structure 18(9):1171-1183. 8 September 2010 (2010)
  Details

  DOI10.1016/j.str.2010.06.015 PMID20826343 PMCID  DivisionStructural Studies
• GANP enhances the efficiency of mRNA nuclear export in mammalian cells AuthorsWickramasinghe V. O., Stewart M., Laskey R. A. Journal Nucleus 1(5):393-396. September - October 2010 (2010)
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  DOI10.4161/nucl.1.5.12351 PMID21326821 PMCIDPMC3037533 DivisionStructural Studies
• Structural basis for the function of the Saccharomyces cerevisiae Gfd1 protein in mRNA nuclear export AuthorsZheng C., Fasken M. B., Marshall N. J., Brockmann C., Rubinson M. E., Wente S. R., Corbett A. H., Stewart M. Journal Journal of Biological Chemistry 285(27):20704-20715. 2 July 2010 (2010)
  Details

  DOI10.1074/jbc. M110.107276 PMID20463024 PMCIDPMC2898303 DivisionStructural Studies
• Novel binding of the mitotic regulator TPX2 (target protein for Xenopus kinesin-like protein 2) to importin‑alpha AuthorsGiesecke A., Stewart M. Journal Journal of Biological Chemistry 285(23):17628-17635. 4 June 2010 (2010)
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  DOI10.1074/jbc. M110.102343 PMID20335181 PMCIDPMC2878527 DivisionStructural Studies
• Simulation of cell motility that reproduces the force-velocity relationship AuthorsSchreiber C. H., Stewart M., Duke T. Journal Proceedings of the National Academy of Sciences, USA 107(20):9141-9146. 18 May 2010 (2010)
  Details

  DOI10.1073/pnas.1002538107 PMID20439759 PMCIDPMC2889078 DivisionStructural Studies
• Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1 AuthorsEllisdon A. M., Jani D., Köhler A., Hurt E., Stewart M. Journal Journal of Biological Chemistry 285(6):3850-3856. 5 February 2010 (2010)
  Details

  DOI10.1074/jbc. M109.070839 PMID20007317 PMCIDPMC2823527 DivisionStructural Studies
• mRNA export from mammalian cell nuclei is dependent on GANP AuthorsWickramasinghe V. O., McMurtrie P. I. A., Mills A. D., Takei Y., Penrhyn-Lowe S., Amagase Y., Main S., Marr J., Stewart M., Laskey R. A. Journal Current Biology 20(1):25-31. 12 January 2010 (2010)
  Details

  DOI10.1016/j. Cub.2009.10.078 PMID20005110 PMCIDPMC2869303 DivisionStructural Studies
• Nuclear export of small RNAs AuthorsStewart M. Journal Science 326(5957):1195-1196. 27 November 2009 (2009)
  Details

  DOI10.1126/science.1183273 PMID19965455 PMCID  DivisionStructural Studies
• Dephosphorylation of major sperm protein (MSP) fiber protein 3 by protein phosphatase 2A during cell body retraction in the MSP-based amoeboid motility of Ascaris sperm AuthorsKexi Yi, Xu Wang, Mark R. Emmett, Alan G. Marshall, Murray Stewart, Thomas M. Roberts Journal Molecular Biology of the Cell 20(14):3200-3208. 15 July 2009 (2009)
  Details

  DOI10.1091/mbc. E09-03‑0240 PMID19458186 PMCIDPMC2710834 DivisionStructural Studies
• Mutational uncoupling of the role of Sus1 in nuclear pore complex targeting of an mRNA export complex and histone H2B deubiquitination AuthorsChristoph Klöckner, Maren Schneider, Sheila Lutz, Divyang Jani, Dieter Kressler, Murray Stewart, Ed Hurt, Alwin Köhler Journal Journal of Biological Chemistry 284(18):12049-12056. 1 May 2009 (2009)
  Details

  DOI10.1074/jbc. M900502200 PMID19269973 PMCIDPMC2673274 DivisionStructural Studies
• Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export AuthorsDivyang Jani, Sheila Lutz, Neil J. Marshall, Tamás Fischer, Alwin Köhler, Andrew M. Ellisdon, Ed Hurt, Murray Stewart Journal Molecular Cell 33(6):727-37 (2009) (2009)
  Details

  DOI10.1016/j.molcel.2009.01.033 PMID19328066 PMCID  DivisionStructural Studies
• Structural requirements for the ubiquitin-associated domain of the mRNA export factor Mex67 to bind its specific targets, the transcription elongation THO complex component Hpr1 and nucleoporin FXFG repeats AuthorsMaria Hobeika, Christoph Brockmann, Florian Gruessing, David Neuhaus, Gilles Divita, Murray Stewart, Catherine Dargemont Journal Journal of Biological Chemistry 284(26):17575-17583 (2009) (2009)
  Details

  DOI10.1074/jbc. M109.004374 PMID19401465 PMCID  DivisionStructural Studies
• Structure of the N-terminal Mlp1-binding domain of the Saccharomyces cerevisiae mRNA-binding protein, Nab2 AuthorsRichard P. Grant, Neil J. Marshall, Ji-Chun Yang, Milo B. Fasken, Seth M. Kelly, Michelle T. Harreman, David Neuhaus, Anita H. Corbett, Murray Stewart Journal Journal of Molecular Biology 376 (4): 1048-59 (2008)
  Details

  DOI  PMID18190927 PMCIDPMC2728203 Division 
• Structural basis for the nuclear import of the human androgen receptor AuthorsMark L. Cutress, Hayley C. Whitaker, Ian G. Mills, Murray Stewart, David E. Neal Journal Journal of Cell Science 121 (Pt 7): 957-968 (2008)
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  DOI  PMID18319300 PMCID  Division 
• The role of filament-packing dynamics in powering amoeboid cell motility AuthorsMiao L., Vanderlinde O., Liu J., Grant R. P., Wouterse A., Shimabukuro K., Philipse A., Stewart M., Roberts T. M. Journal Proceedings of the National Academy of Sciences of the United States of America 105 (14): 5390-5395 (2008)
  Details

  DOI  PMID18385381 PMCID  Division 
• Functional Significance of the Interaction between the mRNA-binding Protein, Nab2, and the Nuclear Pore-associated Protein, Mlp1, in mRNA Export AuthorsMilo B. Fasken, Murray Stewart, Anita H. Corbett Journal Journal of Biological Chemistry 283 (40): 27130-27143 (2008)
  Details

  DOI  PMID18682389 PMCIDPMC2555995 Division 
• Kap95p Binding Induces the Switch Loops of RanGDP to Adopt the GTP-Bound Conformation: Implications for Nuclear Import Complex Assembly Dynamics AuthorsJade K. Forwood, Thierry G. Lonhienne, Mary Marfori, Gautier Robin, Weining Meng, Gregor Guncar, Sai M. Liu, Murray Stewart, Bernard J. Carroll, Bostjan Kobe Journal Journal of Molecular Biology 383 (4): 772-782 (2008)
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  DOI  PMID18708071 PMCID  Division 
• Structural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T AuthorsKenji Murakami, Murray Stewart, Kayo Nozawa, Kumiko Tomii, Norio Kudou, Noriyuki Igarashi, Yasuo Shirakihara, Soichi Wakatsuki, Takuo Yasunaga, Takeyuki Wakabayashi Journal Proceedings of the National Academy of Sciences of the United States of America 105 (20): 7200-7205 (2008)
  Details

  DOI  PMID18483193 PMCID PMC2438227 Division 
• Classical nuclear localization signals: definition, function, and interaction with importin alpha AuthorsLange A., Mills R. E., Lange C. J., Stewart M., Devine S. E., Corbett A. H. Journal Journal of Biological Chemistry 282(8): 5101-5105 (2007) (2007)
  Details

  DOI10.1074/jbc.r600026200 PMID17170104 PMCIDPMC4502416 DivisionStructural Studies
• Coordination of Hpr1 and ubiquitin binding by the UBA domain of the mRNA export factor Mex67 AuthorsMaria Hobeika, Christoph Brockmann, Nahid Iglesias, Carole Gwizdek, David Neuhaus, Francoise Stutz, Murray Stewart, Gilles Divita, Catherine Dargemont Journal Mol Biol Cell 18(7): 2561-2568 (2007) (2007)
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• Molecular mechanism of the nuclear protein import cycle AuthorsMurray Stewart Journal Nat Rev Mol Cell Biol 8(3): 195-208 (2007) (2007)
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• Ratcheting mRNA out of the Nucleus AuthorsMurray Stewart Journal Molecular Cell 25(3): 327-330 (2007) (2007)
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• A Ser/Thr kinase required for membrane-associated assembly of the major sperm protein motility apparatus in the amoeboid sperm of Ascaris AuthorsKexi Yi, Shawnna M. Buttery, Murray Stewart, Thomas M. Roberts Journal Mol Biol Cell 18(5): 1816-1825 (2007) (2007)
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• Karyopherin flexibility in nucleocytoplasmic transport AuthorsElena Conti, Christoph W. Muller, Murray Stewart Journal Current Opinion in Structural Biology 16: 237-244 (2006) (2006)
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• Structural basis for the nuclear protein import cycle AuthorsM. Stewart Journal Biochemical Society Transactions 34: 701-704 (2006) (2006)
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• Nup50/Npap60 function in nuclear protein import complex disassembly and importin recycling AuthorsMatsuura Y., Stewart M. Journal EMBO Journal 24(21):3681-3689. 2 November 2005 (2005)
  Details

  DOI10.1038/sj.emboj.7600843 PMID16222336 PMCIDPMC1276725 DivisionStructural Studies
• Structural basis for nuclear import complex dissociation by RanGTP AuthorsLee S. J., Matsuura Y., Liu A. M., Stewart M. Journal Nature 435(7042):693-696. 2 June 2005 (2005)
  Details

  DOI10.1038/nature03578 PMID15864302 PMCID  DivisionStructural Studies
• Structure of MFP2 and its function in enhancing MSP polymerization in Ascaris sperm amoeboid motility AuthorsRichard P. Grant, Shawnna M. Buttery, Gail C. Ekman, Thomas M. Roberts, Murray Stewart Journal Journal of Molecular Biology 347: 583-595 (2005) (2005)
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• Structural basis for vertebrate filamin dimerization AuthorsRegina Pudas, Tiila-Riikka Kiema, P. Jonathan G. Butler, Murray Stewart, Jari Ylanne Journal Structure 13: 111-119 (2005) (2005)
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• Structural basis for the high-affinity binding of nucleoporin Nup1p to the Saccharomyces cerevisiae importin-beta homologue, Kap95p AuthorsSai Man Liu, Murray Stewart Journal Journal of Molecular Biology 349: 515-525 (2005) (2005)
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• Cytoskeleton dynamics powers nematode sperm motility AuthorsStewart M., Roberts T. M. Journal Advances in Protein Chemistry 71: 383-399 (2005) (2005)
  Details

  DOI10.1016/s0065-3233(04)71010‑4 PMID16230117 PMCID  Division 
• Structural basis for the assembly of a nuclear export complex AuthorsYoshiyuki Matsuura, Murray Stewart Journal Nature 432: 872-877 (2004) (2004)
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• Structural basis for the interaction between the Tap/NXF1 UBA domain and FG nucleoporins at 1 Angstrom resolution AuthorsGrant R. P., Neuhaus D., Stewart M. Journal Journal of Molecular Biology 326(3):849-858. 21 February 2003 (2003)
  Details

  DOI10.1016/s0022-2836(02)01474-2 PMID12581645 PMCID  DivisionStructural Studies
• Loss of myosin VI reduces secretion and the size of the Golgi in fibroblasts from Snell's waltzer mice AuthorsClaire L. Warner, Abigail Stewart, J. Paul Luzio, Karen P. Steel, Richard T. Libby, John Kendrick-Jones, Folma Buss Journal EMBO Journal 22: 569-579 (2003) (2003)
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• Solution NMR study of the interaction between NTF2 and nucleoporin FxFG repeats AuthorsJonathan Morrison, Ji-Chun Yang, Murray Stewart, David Neuhaus Journal Journal of Molecular Biology 333: 587-603 (2003) (2003)
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• Nuclear trafficking AuthorsMurray Stewart Journal Science 302: 1513-1514 (2003) (2003)
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• Structural basis for Nup2p function in cargo release and karyopherin recycling in nuclear import AuthorsYoshiyuki Matsuura, Allison Lange, Michelle T. Harreman, Anita H. Corbett, Murray Stewart Journal EMBO Journal 22: 5358-5369 (2003) (2003)
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• Retraction in amoeboid cell motility powered by cytoskeletal dynamics AuthorsLong Miao, Orion Vanderlinde, Murray Stewart, Thomas M. Roberts Journal Science 302: 1405-1407 (2003) (2003)
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• A 48 kDa integral membrane phosphoprotein orchestrates the cytoskeletal dynamics that generate amoeboid cell motility in Ascaris sperm AuthorsLawrence L. LeClaire III, Murray Stewart, Thomas M. Roberts Journal Journal of Cell Science 116: 2655-2663 (2003) (2003)
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• GLFG and FxFG nucleoporins bind to overlapping sites on importin‑beta AuthorsBayliss R., Littlewood T., Strawn L. A., Wente S. R., Stewart M. Journal Journal of Biological Chemistry 277(52):50597-50606. 27 December 2002 (2002)
  Details

  DOI10.1074/jbc.m209037200 PMID12372823 PMCID  DivisionStructural Studies
• The molecular mechanism of translocation through the nuclear pore complex is highly conserved AuthorsFeldherr C., Akin D., Littlewood T., Stewart M. Journal Journal of Cell Science 115(Pt 14):2997-3005. 15 June 2002 (2002)
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  DOI  PMID12082159 PMCID  DivisionStructural Studies
• 2.6 Angstrom resolution crystal structure of helices of the motile major sperm protein (MSP) of Caenorhabditis elegans AuthorsBaker A. M. E., Roberts T. M., Stewart M. Journal Journal of Molecular Biology 319(2):491-499. 31 May 2002 (2002)
  Details

  DOI10.1016/s0022-2836(02)00294-2 PMID12051923 PMCID  DivisionStructural Studies
• Structure of the C-terminal FG-nucleoporin binding domain of Tap/NXF1 AuthorsGrant R. P., Hurt E., Neuhaus D., Stewart M. Journal Nature Structural Biology 9(4):247-251. 4 March 2002 (2002)
  Details

  DOI10.1038/nsb773 PMID11875519 PMCID  DivisionStructural Studies
• Interaction of CD22 with alpha2,6-linked sialoglycoconjugates: innate recognition of self to dampen B cell autoreactivity? AuthorsLanoue A., Batista F. D., Stewart M., Neuberger M. S. Journal European Journal of Immunology 32(2):348-355. February 2002 (2002)
  Details

  DOI10.1002/1521-4141(200202)32:2<348::aid-immu348>3.0. Co;2-5 PMID11807774 PMCID  DivisionProtein & Nucleic Acid Chemistry
• How nematode sperm crawl AuthorsBottino D., Mogilner A., Roberts T., Stewart M., Oster G. Journal Journal of Cell Science 115(Pt 2):367-384. 15 January 2002 (2002)
  Details

  DOI  PMID11839788 PMCID  DivisionStructural Studies
• NTF2 monomer-dimer equilibrium AuthorsChaillan-Huntington C., Butler J. P. G., Huntington J. A., Akin D., Feldherr C., Stewart M. Journal Journal of Molecular Biology 314(3):465-477 (2001) (2001)
  Details

  DOI10.1006/jmbi.2001.5136 PMID11846560 PMCID  Division 
• Structural basis for bending tropomyosin around actin in muscle thin filaments AuthorsStewart M. Journal Proceedings of the National Academy of Sciences, USA 98(15):8165-8166 (2001) (2001)
  Details

  DOI10.1073/pnas.151265198 PMID11459946 PMCIDPMC37414 DivisionStructural Studies
• Molecular mechanism of translocation through nuclear pore complexes during nuclear protein import AuthorsStewart M., Baker R. P., Bayliss R., Clayton L., Grant R. P., Littlewood T., Matsuura Y. Journal FEBS Letters 498(2-3):145-149 (2001) (2001)
  Details

  DOI10.1016/S0014-5793(01)02489‑9 PMID11412846 PMCID  Division 
• Structural basis for the interaction between FxFG nucleoporin repeats and importin-β in nuclear trafficking AuthorsBayliss R., Littlewood T., Stewart M. Journal Cell 102(1):99-108. 7 July 2000 (2000)
  Details

  DOI10.1016/s0092-8674(00)00014‑3 PMID10929717 PMCID  DivisionStructural Studies
• The molecular mechanism of transport of macromolecules through nuclear pore complexes AuthorsBayliss R., Corbett A. H., Stewart M. Journal Traffic 1(6):448-456 (2000) (2000)
  Details

  DOI10.1034/j.1600-0854.2000.010602.x PMID11208130 PMCID  Division 
• 1.9 angstrom resolution crystal structure of the Saccharomyces cerevisiae Ran-binding protein Mog1p AuthorsStewart M., Baker R. P. Journal Journal of Molecular Biology 299(1):213-223 (2000) (2000)
  Details

  DOI10.1006/jmbi.2000.3733 PMID10860733 PMCID  DivisionStructural Studies
• Structural basis for the higher Ca2+-activation of the regulated actin-activated myosin ATPase observed with Dictyostelium/Tetrahymena actin chimeras AuthorsMatsuura Y., Stewart M., Kawamoto M., Kamiya N., Saeki K., Yasunaga T., Wakabayashi T. Journal Journal of Molecular Biology 296(2):579-595. 19 February 2000 (2000)
  Details

  DOI10.1006/jmbi.1999.3467 PMID10669610 PMCID  DivisionStructural Studies
• Crystallization and preliminary x-ray diffraction analysis of the Saccharomyces cerevisiae Ran-binding protein Mog1p AuthorsBaker R. P., Stewart M. Journal Acta Crystallographica. Section D: Biological Crystallography D56: 229-231 (2000) (2000)
  Details

  DOI10.1107/s0907444999016856 PMID10666614 PMCID  DivisionStructural Studies
• Insights into the molecular mechanism of nuclear trafficking using nuclear transport factor 2 (NTF2) AuthorsStewart M. Journal Cell Structure and Function 25(4):217-225 (2000) (2000)
  Details

  DOI10.1247/csf.25.217 PMID11129791 PMCID  DivisionStructural Studies
• Interaction between NTF2 and xFxFG-containing nucleoporins is required to mediate nuclear import of RanGDP AuthorsBayliss R., Ribbeck K., Akin D., Kent H. M., Feldherr C. M., Gorlich D., Stewart M. Journal Journal of Molecular Biology 293(3):579-593 (1999 ) (1999)
  Details

  DOI10.1006/jmbi.1999.3166 PMID10543952 PMCID  DivisionStructural Studies
• Localized depolymerization of the major sperm protein cytoskeleton correlates with the forward movement of the cell body in the amoeboid movement of nematode sperm AuthorsItaliano Jr J. E., Stewart M., Roberts T. M. Journal Journal of Cell Biology 146(5):1087-1096 (1999 ) (1999)
  Details

  DOI10.1083/jcb.146.5.1087 PMID10477761 PMCIDPMC2169480 Division 
• Molecular architecture of the rod domain of the Dictyostelium gelation factor (ABP120) AuthorsFucini P., Köppel B., Schleicher M., Lustig A., Holak T. A., Müller R., Stewart M., Noegel A. A. Journal Journal of Molecular Biology 291(5):1017-1023 (1999 ) (1999)
  Details

  DOI10.1006/jmbi.1999.3046 PMID10518939 PMCID  DivisionStructural Studies
• Structural basis for dimerization of the Dictyostelium gelation factor (ABP120) rod AuthorsMcCoy A. J., Fucini P., Noegel A. A., Stewart M. Journal Nature Structural Biology 6(9):836-841 (1999) (1999)
  Details

  DOI10.1038/12296 PMID10467095 PMCID  DivisionStructural Studies
• Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import AuthorsHelen M. Kent, Mary Shannon Moore, B. Booth Quimby, Anne M. E. Baker, Airlie J. McCoy, Gretchen A. Murphy, Anita H. Corbett, Murray Stewart Journal Journal of Molecular Biology 289(3):565-577 (1999) (1999)
  Details

  DOI10.1006/jmbi.1999.2775 PMID10356329 PMCID  Division 
• Switching affinities in nuclear trafficking AuthorsStewart M., Rhodes D. Journal Nature Structural Biology 6(4):301-304 (1999) (1999)
  Details

  DOI10.1038/7529 PMID10201390 PMCID  DivisionStructural Studies
• Location of the binding site of the mannose-specific lectin comitin on F‑Actin AuthorsFulgenzi G., Graciotti L., Granata A. L., Corsi A., Fucini P., Noegel A. A.,Kent H. M., Stewart M. Journal Journal of Molecular Biology 284(5):1255-1263. 18 December 1998 (1998)
  Details

  DOI10.1006/jmbi.1998.2294 PMID9878346 PMCID  Division 
• Solution structure of the motile major sperm protein (MSP) of Ascaris suum - evidence for two manganese binding sites and the possible role of divalent cations in filament formation AuthorsAndreas Haaf, Lawrence LeClaire III, Gregory Roberts, Helen M. Kent, Thomas M. Roberts, Murray Stewart, David Neuhaus Journal Journal of Molecular Biology 284(5):1611-1624. 18 December 1998 (1998)
  Details

  DOI10.1006/jmbi.1998.2291 PMID9878374 PMCID  DivisionStructural Studies
• The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2) AuthorsStewart M., Kent H. M., McCoy A. J. Journal Journal of Molecular Biology 284(5):1517-1527. 18 December 1998 (1998)
  Details

  DOI10.1006/jmbi.1998.2204 PMID9878368 PMCID  DivisionStructural Studies
• NTF2 mediates nuclear import of Ran AuthorsRibbeck K., Lipowsky G., Kent H. M., Stewart M., Gorlich D. Journal EMBO Journal 17(22):6587-6598. 16 November 1998 (1998)
  Details

  DOI10.1093/emboj/17.22.6587 PMID9822603 PMCIDPMC1171005 DivisionStructural Studies
• Structural basis for amoeboid motility in nematode sperm AuthorsTimothy L. Bullock, Airlie J. McCoy, Helen M. Kent, Thomas M. Roberts, Murray Stewart Journal Nature Structural Biology 5: 184-189 (1998) (1998)
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• Hydrostatic pressure shows that lamellipodial motility in Ascaris sperm requires membrane-associated major sperm protein filament nucleation and elongation AuthorsThomas M. Roberts, E. D. Salmon, Murray Stewart Journal Journal of Cell Biology 140: 367-375 (1998) (1998)
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• Structural basis for molecuar recognition between nuclear transport factor 2 (NTF2) and the GDP-bound form of the Ras-family GTPase Ran AuthorsMurray Stewart, Helen M. Kent, Airlie J. McCoy Journal Journal of Molecular Biology 277: 635-646 (1998) (1998)
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• Amoeboid motility without actin: insights into the molecular mechanism of locomotion using the major sperm protein (MSP) of nematodes AuthorsMurray Stewart, Thomas M. Roberts, Joseph E. Italiano Jr, Karen L. King, Robin Hammel, G. Parathasathy, Timothy L. Bullock, Airlee J. McCoy, Helen Kent, Andreas Haaf, David Neuhaus Journal Biol. Bull. 194: 342-344 (1998) (1998)
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• Molecular interactions between the importin alpha/beta heterodimer and proteins involved in vertebrate nuclear protein import AuthorsPiergiorgio Percipalle, W. David Clarkson, Helen M. Kent, Daniela Rhodes, Murray Stewart Journal Journal of Molecular Biology 266(4):722-732. 7 March 1997 (1997)
  Details

  DOI10.1006/jmbi.1996.0801 PMID9102465 PMCID  Division 
• Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (NTF2) that do not bind GDP‑RAN AuthorsW. David Clarkson, Anita H. Corbett, Bryce M. Paschal, Helen M. Kent, Airlie J. McCoy, Larry Gerace, Pamela A. Silver, Murray Stewart Journal Journal of Molecular Biology 272: 716-730 (1997) (1997)
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• Nematode sperm: amoeboid movement without actin AuthorsRoberts T. M., Stewart M. Journal Trends in Cell Biology 7(9):368-373(1997) (1997)
  Details

  DOI10.1016/S0962-8924(97)01113‑6 PMID17708982 PMCID  Division 
• Interaction between the small GTPase Ran/Gsp1p and Ntf2p is required for nuclear transport AuthorsDarren H. Wong, Anita H. Corbett, Helen M. Kent, Murray Stewart, Pamela A. Silver Journal Molecular and Cellular Biology 17: 3755-3767 (1997) (1997)
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• Separate binding sites on nuclear transport factor 2 (NTF2) for GDP-Ran and the phenylalanine-rich repeat regions of nucleoporins p62 and Nsp1p AuthorsClarkson W. D., Kent H. M., Stewart M. Journal Journal of Molecular Biology 263(4):517-524. 8 November 1996 (1996)
  Details

  DOI10.1006/jmbi.1996.0594 PMID8918934 PMCID  DivisionStructural Studies
• 2.5 angstrom resolution crystal structure of the motile major sperm protein (MSP) of Ascaris suum AuthorsBullock T. L., Roberts T. M., Stewart M. Journal Journal of Molecular Biology 263(2):284-296.25 October 1996 (1996)
  Details

  DOI10.1006/jmbi.1996.0575 PMID8913307 PMCID  DivisionStructural Studies
• The 1.6 angstrom resolution crystal structure of nuclear transport factor 2 (NTF2) AuthorsBullock T. L., Clarkson W. D., Kent H. M., Stewart M. Journal Journal of Molecular Biology 260(3):422-431. 19 July 1996 (1996)
  Details

  DOI10.1006/jmbi.1996.0411 PMID8757804 PMCID  DivisionStructural Studies
• The motile major sperm protien (MSP) from Ascaris suum is a symmetric dimer in solution AuthorsHaaf A., P. Butler J. G., Kent H. M., Fearnley I. M., Roberts T. M., Neuhaus D., Stewart M. Journal Journal of Molecular Biology 260(2):251-260.12 July 1996 (1996)
  Details

  DOI10.1006/jmbi.1996.0396 PMID8764404 PMCID  DivisionStructural Studies
• Reconstitution in vitro of the motile apparatus from the amoeboid sperm of Ascaris shows that filament assembly and bundling move membranes AuthorsJoseph E. Italiano Jr, Thomas M. Roberts, Murray Stewart, Carolyn A. Fontana Journal Cell 84: 105-114 (1996) (1996)
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• Linking microfilaments to intracellular membranes: the actin-binding and vesicle-associated protein comitin exhibits a mannose-specific lectin activity AuthorsEva Jung, Paola Fucini, Murray Stewart, Angelika A. Noegel, Michael Schleicher Journal EMBO Journal 15: 1238-1246 (1996) (1996)
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• Structure and function of the salachian egg case AuthorsDavid P. Knight, Dian Feng, Murray Stewart Journal Biol. Rev. 71: 81-111 (1996) (1996)
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• Nuclear pores and macromolecular assemblies involved in nucleocytoplasmic transport AuthorsMurray Stewart, W. David Clarkson Journal Current Opinion in Structural Biology 6: 162-165 (1996) (1996)
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• Macromolecular interactions in the nucleoporin p62 complex of rat nuclear pores: binding of nucleoporin p54 to the rod domain of p62 AuthorsFolma Buss, Murray Stewart Journal Journal of Cell Biology 128: 251-261 (1995) (1995)
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• Nematode sperm locomotion AuthorsThomas M. Roberts, Murray Stewart Journal Current Opinion in Cell Biology 7: 13-17 (1995) (1995)
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• Role of different domains in the self-association of rat nucleoporin p62 AuthorsBuss F., Kent H., Stewart M., Bailer S. M., Hanover J. A. Journal Journal of Cell Sci ence 107 ( Pt 2):631-638(1994) (1994)
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  DOI  PMID8207085 PMCID  Division 
• The motile major sperm protein (MSP) of Ascaris suum forms filaments constructed from two helical subfilaments AuthorsMurray Stewart, Karen L. King, Thomas M. Roberts Journal Journal of Molecular Biology 243: 60-71 (1994) (1994)
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• Supramolecular assemblies of the Ascaris suum major sperm protein (MSP) associated with amoeboid cell motility AuthorsKaren L. King, Murray Stewart, Thomas M. Roberts Journal Journal of Cell Science 107: 2941-2949 (1994) (1994)
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• Crystallization of the motile major sperm protein (MSP) of the nematode Ascaris suum AuthorsStewart M., King K. L., Roberts T. M. Journal Journal of Molecular Biology 232(1):298-300. 5 July 1993 (1993)
  Details

  DOI10.1006/jmbi.1993.1383 PMID8331665 PMCID  DivisionStructural Studies
• Intermediate filament structure and assembly AuthorsMurray Stewart Journal Current Opinion in Cell Biology 5: 3-11 (1993) (1993)
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• The relaxed crossbridge pattern in isolated rabbit psoas muscle thick filaments AuthorsRobert W. Kensler, Murray Stewart Journal Journal of Cell Science 105: 841-848 (1993) (1993)
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• Changes in macromolecular organization in collagen assemblies during secretion in the nidamental gland and formation of the egg capsule wall in the dogfish Scyliorhinus canicula AuthorsDavid P. Knight, Dian Feng, Murray Stewart, Elizabeth King Journal Phil. Trans. R. Soc. Lond. B 341: 419-436 (1993) (1993)
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• Structure of tropomyosin at 9 angstroms resolution AuthorsWhitby F. G., Kent H., Stewart F., Stewart M., Xie X., Hatch V., Cohen C., Phillips Jr G. N. Journal Journal of Molecular Biology 227(2):441-452. 20 September 1992 (1992)
  Details

  DOI10.1016/0022-2836(92)90899‑U PMID1404362 PMCID  DivisionStructural Studies
• Molecular interactions in myosin assembly. Role of the 28-residue charge repeat in the rod AuthorsSimon J. Atkinson, Murray Stewart Journal Journal of Molecular Biology 226: 7-13 (1992) (1992)
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• Pathway of incorporation of microinjected lamin A into the nuclear envelope AuthorsAnne E. Goldman, Robert D. Moir, Michelle Montag-Lowy, Murray Stewart, Robert D. Goldman Journal Journal of Cell Biology 119: 725-735 (1992) (1992)
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• Structure and macromolecular assembly of two isoforms of the major sperm protein (MSP) from the amoeboid sperm of the nematode, Ascaris suum AuthorsKaren L. King, Murray Stewart, Thomas M. Roberts, Margaret Seavy Journal Journal of Cell Science 101: 847-857 (1992) (1992)
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• A brief introduction to aims and methods for image processing of electron micrographs of biological specimens AuthorsStewart M. Journal Scanning Microscopy Supplement 6: 3-9 (1992) (1992)
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• Macromolecular structure and aggregation states of Helicobacter pylori urease AuthorsJohn W. Austin, Peter Doig, Murray Stewart, Trevor J. Trust Journal Journal of Bacteriology 173(18):5663-5667 (1991 ) (1991)
  Details

  DOI10.1128/jb.173.18.5663-5667.1991 PMID1885543 PMCIDPMC208295 DivisionStructural Studies
• Molecular basis of myosin assembly: coiled-coil interactions and the role of charge periodicities AuthorsSimon J. Atkinson, Murray Stewart Journal Journal of Cell Science Supplement 14: 7-10 (1991) (1991)
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  DOI  PMID1885663 PMCID  Division 
• Expression in Escherichia coli of human lamins A and C: influence of head and tail domains on assembly properties and paracrystal formation AuthorsRobert D. Moir, Anne D. Donaldson, Murray Stewart Journal Journal of Cell Science 99: 363-372 (1991) (1991)
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• Nuclear envelope dynamics and nucleocytoplasmic transport AuthorsMurray Stewart, Sue Whytock, Robert D. Moir Journal Journal of Cell Science Supplement 14: 79-82 (1991) (1991)
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• Cloning and sequencing of rat plectin indicates a 466-kD polypeptide chain with a three-domain structure based on a central alpha-helical colied coil AuthorsGerhard Wiche, Bruno Becker, Karin Luber, Georg Weitzer, Maria J. Castanon, Rudolf Hauptmann, Christian Stratowa, Murray Stewart Journal Journal of Cell Biology 114: 83-99 (1991 ) (1991)
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• Transmission electron microscopy of vitrified biological macromolecular assemblies AuthorsStewart M. Journal Electron Microscopy in Biology: A Practical Approach pp.229-242 (1991) (1991)
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• Expression in Escherichia coli of fragments of the coiled-coil rod domain of rabbit myosin: Influence of diferent regions of the molecule on aggregation and paracrystal formation AuthorsAtkinson S. J., Stewart M. Journal Journal of Cell Science 99 ( Pt 4):823-836 (1991) (1991)
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• Selective digestion of nuclear envelopes from Xenopus oocyte germinal vesicles: possible structural role for the nuclear lamina AuthorsWhytock S., Moir R. D., Stewart M. Journal Journal of Cell Science 97 (3): 571-80. November 1990 (1990)
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  DOI10.1242/jcs.97.3.571 PMID1705942 PMCID  DivisionStructural Studies
• Structural predictions for the central domain of dystrophin AuthorsCross R. A., Stewart M., Kendrick-Jones J. Journal FEBS Letters 262(1):87-92 (1990) (1990)
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  DOI10.1016/0014-5793(90)80160-k PMID2180744 PMCID  Division 
• Structural and chemical characterization of the S layer of a Pseudomonas-like bacterium AuthorsAustin J. W., Stewart M., Murray R. G. E. Journal Journal of Bacteriology 172(2):808-817. February 1990 (1990)
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  DOI10.1128/jb.172.2.808-817.1990 PMID2298701 PMCIDPMC208510 DivisionStructural Studies
• Intermediate filaments: structure, assembly and molecular interactions AuthorsStewart M. Journal Current Opinion in Cell Biology 2(1):91-100. February 1990 (1990)
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  DOI10.1016/s0955-0674(05)80037-7 PMID2183847 PMCID  DivisionStructural Studies
• High resolution structural studies of two-dimensional crystalline sheets of the long S-2 fragment of myosin rod. (Paper presented at EMAG-MICRO 89, London, 13-15 September 1989) AuthorsReinhard Rachel, Murray Stewart Journal Inst. Phys. Conf. Ser. No 98: Chapter 16, pp.739-742 (1990) (1990)
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• Transmission electron microscopy of frozen hydrated biological material. (Paper presented at EMAG-MICRO 89, London, 13-15 September 1989) AuthorsMurray Stewart Journal Inst. Phys. Conf. Ser. No. 98, Chapter 17: 769-774 (1990) (1990)
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• Expression and characterization of human lamin C AuthorsRobert D. Moir, Roy A. Quinlan, Murray Stewart Journal FEBS Letters 268: 301-305 (1990 ) (1990)
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• Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring AuthorsJed B. Gorlin, Rina Yamin, Sheila Egan, Murray Stewart, Thomas P. Stossel, David J. Kwiatkowski, John H. Hartwig Journal Journal of Cell Biology 111: 1089-1105 (1990 ) (1990)
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• Complete sequence of the Drosophila nonmuscle myosin heavy-chain transcript: conserved sequences in the myosin tail and differential splicing in the 5' untranslated sequence AuthorsAndrew S. Ketchum, C. Todd Stewart, Murray Stewart, Daniel P. Kiehart Journal Proceedings of the National Academy of Sciences, USA 87: 6316-6320 (1990) (1990)
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• Structural predictions for the central domain of dystrophin AuthorsR. A. Cross, Murray Stewart, J. Kendrick-Jones Journal FEBS Letters 262: 87-92 (1990) (1990)
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• Association of gold-labelled nucleoplasmin with the centres of ring components of Xenopus oocyte nuclear pore complexes AuthorsMurray Stewart, Sue Whytock, Anthony D. Mills Journal Journal of Molecular Biology 213: 575-582 (1990) (1990)
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• Electron microscopy of biological macromolecules. Frozen hydrated methods and computer image processing AuthorsMurray Stewart Journal Modern Microscopies. Edited by P. J. Duke and A. G. Michette pp.9-39 (1990) (1990)
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• Resolution. A biological perspective AuthorsMurray Stewart Journal Modern Microscopies. Edited by P. J. Duke and A. G. Michette pp.255-266 (1990) (1990)
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• The Dictyostelium gelation factor shares a putative actin binding site with alpha-actinins and dystrophin and also has a rod domain containing six 100-residue motifs that appear to have a cross-beta conformation AuthorsAngelika A. Noegel, Susanne Rapp, Friedrich Lottspeich, Michael Schleicher, Murray Stewart Journal Journal of Cell Biology 109(2):607-618 (1989) (1989)
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  DOI10.1083/jcb.109.2.607 PMID2668299 PMCIDPMC2115711 Division 
• Molecular interactions in paracrystals of a fragment corresponding to the alpha-helical coiled-coil rod portion of glial fibrillary acidic protein: evidence for an antiparallel packing of molecules and polymorphism related to intermediate filament structure AuthorsMurray Stewart, Roy A. Quinlan, Robert D. Moir Journal Journal of Cell Biology 109(1):225-234 (1989) (1989)
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  DOI10.1083/jcb.109.1.225 PMID2745549 PMCIDPMC2115473 Division 
• Expression in Escherichia coli of fragments of glial fibrillary acidic protein: characterization, assembly properties and paracrystal formation AuthorsRoy A. Quinlan, Robert D. Moir, Murray Stewart Journal Journal of Cell Science 93: 71-83 (1989) (1989)
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• An ultrastructural study of crossbridge arrangement in the fish skeletal muscle thick filament AuthorsRobert W. Kensler, Murray Stewart Journal Journal of Cell Science 94: 391-401 (1989) (1989)
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• Transmission electron microscopy of frozen hydrated biological material AuthorsMurray Stewart Journal Electron Microsc. Rev. 2: 117-121 (1989) (1989)
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• Preparation of shadowed nuclear envelopes from Xenopus oocyte germinal vesicles for electron microscopy AuthorsSue Whytock, Murray Stewart Journal Journal of Microscopy 151: 115-126 (1988) (1988)
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• The structure and interactions of components of nuclear envelopes from Xenopus oocyte germinal vesicles observed by heavy metal shadowing AuthorsMurray Stewart, Sue Whytock Journal Journal of Cell Science 90: 409-423 (1988) (1988)
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• Computer image processing of electron micrographs of regular biological objects such as crystals, helices and shells AuthorsMurray Stewart Journal J. Microsc. Spectrosc. Electron 13: 451-462 (1988) (1988)
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• Computer image processing of electron micrographs of biological structures with helical symmetry AuthorsMurray Stewart Journal Journal of Electron Microscopy Technique 9: 325-358 (1988) (1988)
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• Introduction to the computer image processing of electron micrographs of two-dimensionally ordered biological structures AuthorsMurray Stewart Journal Journal of Electron Microscopy Techniques 9: 301-324 (1988) (1988)
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• Crystalline tubes of myosin subfragment-2 showing the coiled-coil and molecular interaction geometry AuthorsQuinlan R. A., Stewart M. Journal Journal of Cell Biology 105(1):403-415. 1 July 1987 (1987)
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  DOI10.1083/jcb.105.1.403 PMID3611193 PMCIDPMC2114931 DivisionStructural Studies
• A new crystal form of Tropomyosin. Preliminary X-ray diffraction analysis AuthorsGeorge N. Phillips Jr., Carolyn Cohen, Murray Stewart Journal Journal of Molecular Biology 195: 219-223 (1987) (1987)
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• A model to account for the elastic element muscle crossbridges in terms of a bending myosin rod AuthorsMurray Stewart, A. D. McLachlan Journal Proc. R. Soc. Lond. B 229: 381-413 (1987) (1987)
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• Electron microscopy of frozen-hydrated biological material AuthorsStewart M., Vigers G. Journal Nature 319(6055):631-636. 20 February 1986 (1986)
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  DOI10.1038/319631a0 PMID3951536 PMCID  DivisionStructural Studies
• An ultrastructural study of cross-bridge arrangement in the frog thigh muscle thick filament AuthorsRobert W. Kensler, Murray Stewart Journal Biophysical Journal 49(1):343-351 (1986) January 1986 (1986)
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  DOI10.1016/S0006-3495(86)83647-5 PMID3485451 PMCIDPMC1329646 DivisionStructural Studies
• Two patterns in the Aeromonas salmonicida A-layer may reflect a structural transformation that alters permeability AuthorsMurray Stewart, Terry J. Beveridge, Trevor J. Trust Journal Journal of Bacteriology 166: 120-127 (1986) (1986)
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• Computer analysis of ordered microbiological objects AuthorsStewart M. Journal Ultrastructure techniques for microorganisms. Edited by Henry C. Aldrich and William J. Todd pp.333-364 (1986) (1986)
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• Arrangement of myosin heads in relaxed thick filaments from frog skeletal muscle AuthorsMurray Stewart, Robert W. Kensler Journal Journal of Molecular Biology 192: 831-851 (1986) (1986)
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• Cryo-electron microscopy of tropomyosin magnesium paracrystals. AuthorsMurray Stewart, Jean Lepault Journal Journal of Microscopy 138: 53-60 (1985) (1985)
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• Crystalline order to high resolution in the sheath of Methanospirillum hungatei: a cross-beta structure AuthorsMurray Stewart, Terry J. Beveridge, G. Dennis Sprott Journal Journal of Molecular Biology 183: 509-515 (1985) (1985)
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• Analysis of the structure of paired helical filaments AuthorsR. A. Crowther, C. M. Wischik, M. Stewart Journal Proceedings of the 43rd Annual Meeting of the Electron Microscopy Society of America. Edited by G. W. Bailey pp.734-737 (1985) (1985)
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• Subunit stucture of paired helical filaments in Alzheimer's disease AuthorsC. M. Wischik, R. A. Crowther, Murray Stewart, Martin Roth Journal Journal of Cell Biology 100: 1905-1912 (1985) (1985)
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• Unusual stability of the Methanospirillum hungatei sheath AuthorsTerry J. Beveridge, Murray Stewart, Ronald J. Doyle, G. Dennis Sprott Journal Journal of Bacteriology 162: 728-737 (1985) (1985)
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• Electron microscopic and optical diffraction analysis of the structure of scorpion muscle thick filaments AuthorsRobert W. Kensler, Rhea J. C. Levine, Murray Stewart Journal Journal of Cell Biology 101: 395-401 (1985) (1985)
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• Three-dimensional reconstruction of thick filaments from Limulus and scorpion muscle AuthorsMurray Stewart, Robert W. Kensler, Rhea J. C. Levine Journal Journal of Cell Biology 101: 402-411 (1985) (1985)
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• Length of myosin rod and its proteolytic fragments determined by electron microscopy AuthorsMurray Stewart, Pat Edwards Journal FEBS Letters 168: 75-78 (1984) (1984)
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• Crystalline sheets of tropomyosin AuthorsMurray Stewart Journal Journal of Molecular Biology 174: 231-238 (1984) (1984)
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• Crystalline order to a resolution of 4.7 Angstroms in the sheath of Methanospirillum hungatii: a cross-beta structure AuthorsMurray Stewart, T. J. Beveridge, D. Sprott Journal Proceedings of the 42nd Annual Meeting of the Electron Microscopy Society of America. Edited by G. W. Bailey pp.214-215 (1984) (1984)
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• Nuclear magnetic resonance evidence for a flexible region at the C-terminus of alpha‑tropomyosin AuthorsMurray Stewart, Gordon C. K. Roberts Journal Journal of Molecular Biology 166: 219-225 (1983) (1983)
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• Frog skeletal muscle thick filaments are three-stranded AuthorsRobert W. Kensler, Murray Stewart Journal Journal of Cell Biology 96: 1797-1802 (1983) (1983)
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• Chain register in myosin rod AuthorsMurray Stewart Journal FEBS Letters 140: 210-212 (1982) (1982)
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• Interim report on studies on "toxic" effects of human leucocyte-derived interferon-alpha (HuIFN-alpha) AuthorsG. M. Scott, J. Wallace, D. A. J. Tyrrell, K. Cantell, D. S. Secher, W. E. Stewart, II Journal Journal of Interferon Research 2: 127-130 (1982) (1982)
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• Periodic charge distribution in the intermediate filament proteins desmin and vimentin AuthorsAndrew D. McLachlan, Murray Stewart Journal Journal of Molecular Biology 162: 693-698 (1982) (1982)
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• 1H NMR study of long and short myosin S2 fragments AuthorsMurray Stewart, Gordon C. K. Roberts Journal FEBS Letters 146: 293-296 (1982) (1982)
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• Porcine platelet tropomyosin. Purification, characterization and paracrystal formation AuthorsE. der Terrossian, S. D. Fuller, Murray Stewart, A. G. Weeds Journal Journal of Molecular Biology 153: 147-167 (1981) (1981)
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• The structure of chicken scale keratin AuthorsMurray Stewart Journal Journal of Ultrastructure Research 60: 27-33 (1977) (1977)
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• Structure of magnesium paracrystals of alpha-tropomyosin AuthorsMurray Stewart, A. D. McLachlan Journal Journal of Molecular Biology 103: 251-269 (1976) (1976)
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• The 14-fold periodicity in alpha-tropomyosin and the interaction with actin. Appendix: Fourier transform of a random sequence profile AuthorsA. D. McLachlan, Murray Stewart Journal Journal of Molecular Biology 103: 271-298 (1976) (1976)
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• Muscle structure and function - an explanation AuthorsMurray Stewart Journal Equine Vet. J. 8: 17-19 (1976) (1976)
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• The troponin binding region of tropomyosin. Evidence for a site near residues 197 to 217 AuthorsA. D. McLachlan, Murray Stewart Journal Journal of Molecular Biology 106: 1017-1022 (1976) (1976)
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• Cross-bridge movement during muscle contraction AuthorsJohn C. Haselgrove, Murray Stewart, Hugh E. Huxley Journal Nature 261: 606-608 (1976) (1976)
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• Tropomyosin: evidence for no stagger between chains AuthorsMurray Stewart Journal FEBS Letters 53: 5-7 (1975) (1975)
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• Paramyosin: chemical evidence for chain heterogeneity AuthorsIan D. Walker, Murray Stewart Journal FEBS Letters 58: 16-18 (1975) (1975)
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• Fourteen actin-binding sites on tropomyosin? AuthorsMurray Stewart, A. D. McLachlan Journal Nature 257: 331-333 (1975) (1975)
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• The location of the troponin binding site on tropomyosin AuthorsMurray Stewart Journal Proc. R. Soc. Lond. B. 190: 257-266 (1975) (1975)
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• Sequence repeats in alpha‑tropomyosin AuthorsA. D. McLachlan, Murray Stewart, L. B. Smillie Journal Journal of Molecular Biology 98: 281-291 (1975) (1975)
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• Tropomyosin coiled-coil interactions: evidence for an unstaggered structure AuthorsA. D. McLachlan, Murray Stewart Journal Journal of Molecular Biology 98: 293-304 (1975) (1975)
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