Published Research
Found 10 results for Ryskeldi‑Falcon.
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Seeding biosensor cell line that reproduces the Alzheimer tau fold
AuthorsTaxiarchis Katsinelos, Sofia Lövestam, Chao Qi, Bejamin Ryskeldi-Falcon, Jennifer A. Macdonald, Gabriel Stephenson, Bernardino Ghetti, Ann McKee, Sjors H. W. Scheres, Michel Goedert.
Journal
The Journal of Biological Chemistry
301(12):110952 (2025)
Details
DOI10.1016/j.jbc.2025.110952 PMID41260337 PMCIDPMC12765094 DivisionStructural Studies, Neurobiology - Tau uptake by human neurons depends on receptor LRP1 and kinase LRRK2 AuthorsEvans L.D., Strano A., Tuck E., Campbell A., Smith J., Hung C., Behr T.S., Ghetti B., Ryskeldi-Falcon B., Karakoc E., Iorio F., Reith A., Bassett A.R., Livesey F.J. Journal The EMBO Journal (2025)
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Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease
AuthorsFowler S. L., Behr T. S., Turkes E., O'Brien D. P., Cauhy P. M., Rawlinson I., Edmonds M., Foiani M. S., Schaler A., Crowley G., Bez S., Ficulle E., Tsefou E., Fischer R., Geary B., Gaur P., Miller C., D'Acunzo P., Levy E., Duff K. E., Ryskeldi-Falcon B.
Journal
Nature Neuroscience
28(1):40-48 (2025)
Details
DOIdoi.org/10.1038/s41593-024-01801-5 PMID39572740 PMCIDPMC11706778 DivisionNeurobiology, Cell Biology - Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP type C AuthorsArseni D., Nonaka T., Jacobsen M. H., Murzin A. G., Cracco L., Peak-Chew S. Y., Garringer H. J., Kawakami I., Suzuki H., Onaya M., Saito Y., Murayama S., Geula C., Vidal R., Newell K. L., Mesulam M., Ghetti B., Hasegawa M., Ryskeldi-Falcon B. Journal Nature 634(8034):662-668 (2024)
- TAF15 amyloid filaments in frontotemporal lobar degeneration AuthorsTetter S., Arseni D., Murzin A. G., Buhidma Y., Peak-Chew S. Y., Garringer H. J. Newell K. L., Vidal R., Apostolova L. G., Lashley T., Ghetti B., Ryskeldi-Falcon B. Journal Nature, 625(7994):345-351 (2024)
- Molecular pathology of neurodegenerative diseases by cryo-EM of amyloids AuthorsScheres S. H. W., Ryskeldi-Falcon B., Goedert M. Journal Nature 621(7980):701-710 (2023)
- TDP-43 forms amyloid filaments with a distinct fold in type A FTLD‑TDP AuthorsArseni D., Chen R., Murzin A. G., Peak-Chew S. Y., Garringer H. J., Newell K. L., Kametani F., Robinson A. C., Vidal R., Ghetti B., Hasegawa M., Ryskeldi-Falcon B. Journal Nature 620(7975):898-903 (2023)
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Age-dependent formation of TMEM106B amyloid filaments in human brains
AuthorsSchweighauser M., Arseni D., Bacioglu M., Huang M., Lövestam S., Shi Y., Yang Y., Zhang W., Kotecha A., Garringer H. J., Vidal R., Hallinan G. I., Newell K. L., Tarutani A., Murayama S., Miyazaki M., Saito Y., Yoshida M., Hasegawa K., Lashley T., Revesz T., Kovacs G. G., van Swieten J., Takao M., Hasegawa M., Ghetti B., Spillantini M. G., Ryskeldi-Falcon B., Murzin A. G., Goedert M., Scheres S. H. W.
Journal
Nature
605(7909):310-314 (2022)
Details
DOI10.1038/s41586-022-04650-z PMID35344985 PMCIDPMC9095482 DivisionNeurobiology, Structural Studies -
Cryo-EM structures of amyloid-β 42 filaments from human brains
AuthorsYang Y., Arseni D., Zhang W., Huang M., Lövestam S., Schweighauser M., Kotecha A., Murzin A. G., Peak-Chew S. Y., Macdonald J., Lavenir I., Garringer H. J., Gelpi E., Newell K. L., Kovacs G. G., Vidal R., Ghetti B., Ryskeldi-Falcon B., Scheres S. H. W., Goedert M.
Journal
Science
375(6577):167-172 (2022)
Details
DOI10.1126/science. Abm7285 PMID35025654 PMCIDPMC7612234 DivisionStructural Studies, Neurobiology - Structure of pathological TDP-43 filaments from ALS with FTLD AuthorsArseni D., Hasegawa M., Murzin A. G., Kametani F., Arai M., Yoshida M., Ryskeldi-Falcon B. Journal Nature 601(7891):139-143 (2022)