Published Research
Found 8 results for Ramakrishnan L.
- Structural and functional analysis of the Mycobacterium tuberculosis MmpS5L5 efflux pump presages increased bedaquiline resistance AuthorsFountain A.J., Böhning J., McLaughlin S.H., Morgan T.E., Edelstein P.H., Troll M., Lamers M.H., Bharat T.A.M., Luisi B.F., Ramakrishnan L. Journal Proceedings of the National Academy of Sciences of the United States of America 122(39):e2516660122 (2025)
- A dose-finding study to guide use of verapamil as an adjunctive therapy in tuberculosis AuthorsPadmapriyadarsini C, Szumowski JD, Akbar N, Shanmugasundaram P, Jain A, Bathragiri M, Pattnaik M, Turuk J, Karunaianantham R, Balakrishnan S, Pati S, Kumar AKH, Rathore MK, Raja J, Naidu KR, Horn J, Whitworth L, Sewell R, Ramakrishnan L, Swaminathan S, Edelstein PH. Journal Clinical Pharmacology & Therapeutics Clin Pharmacol Ther. 2023 Nov 20 (2024)
- Redefining tuberculosis: an interview with Lalita Ramakrishnan AuthorsRamakrishnan L Journal Disease Models and Mechanisms 16(3):dmm050189 (2023)
- The human proton pump inhibitors inhibit Mycobacterium tuberculosis rifampicin efflux and macrophage-induced rifampicin tolerance AuthorsLake M. A., Adams K. N., Nie F., Fowler E., Verma A. K., Dei S., Teodori E., Sherman D. R., Edelstein P. H., Spring D. R., Troll M., Ramakrishnan L. Journal Proceedings of the National Academy of Sciences of the United States of America 120(7):e2215512120 (2023)
- Gaucher disease protects against tuberculosis AuthorsFan J, Hale V. L, Lelieveld L. T., Whitworth L. J., Busch-Nentwich E. M., Troll M., Edelstein P. H., Cox T. M., Roca F. J., Aerts J. M. F. G., Ramakrishnan L. Journal Proceedings of the National Academy of Sciences of the United States of America 120(7):e2217673120 (2023)
- mTOR-regulated mitochondrial metabolism limits mycobacterium-induced cytotoxicity AuthorsPagán AJ, Lee LJ, Edwards-Hicks J, Moens CB, Tobin DM, Busch-Nentwich EM, Pearce EL, Ramakrishnan L. Journal Cell Sep 29;185(20):3720-3738.e13 (2022)
- Tumor necrosis factor induces pathogenic mitochondrial ROS in tuberculosis through reverse electron transport AuthorsRoca FJ, Whitworth LJ , Prag HA, Murphy MP, Ramakrishnan L Journal Science Jun 24;376(6600):eabh2841 (2022)
- The C terminus of the mycobacterium ESX-1 secretion system substrate ESAT-6 is required for phagosomal membrane damage and virulence AuthorsOsman M. M., Shanahan J. K., Chu F., Takaki K. K., Pinckert M. L., Pagán A. J., Brosch R., Conrad W. H., Ramakrishnan L. Journal Proceedings of the National Academy of Sciences of the United States of America 119(11):e2122161119 (2022)