Published Research

Found 125 results for Pelham.

• Regulation of Dishevelled DEP domain swapping by conserved phosphorylation sites AuthorsBeitia G. J., Rutherford T. J., Freund S. M. V., Pelham H. R., Bienz M., Gammons M. V. Journal Proceedings of the National Academy of Sciences of the United States of America 118(26). 29 June 2021 (2021)
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  DOI10.1073/pnas.2103258118 PMID34155117 PMCIDPMC8256032 DivisionStructural Studies, Cell Biology, Protein & Nucleic Acid Chemistry
• Towards accurate exclusion of neonatal bacterial meningitis: a feasibility study of a novel 16S rDNA PCR assay AuthorsAbelian A., Mund T., Curran M. D., Savill S. A., Mitra N., Charan C., Ogilvy-Stuart A. L., Pelham H. R. B., Dear P. H. Journal BMC Infectious Diseases 20(1):441. 22 June 2020 (2020)
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  DOI10.1186/s12879-020-05160-x PMID32571220 PMCIDPMC7310343 DivisionCell Biology
• Ubiquitination of alpha-synuclein filaments by Nedd4 ligases AuthorsMund T., Masuda-Suzukake M., Goedert M., Pelham H. R. Journal PloS one 13(7):e0200763. 18 July 2018 (2018)
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  DOI10.1371/journal.pone.0200763 PMID30021006 PMCIDPMC6051637 DivisionNeurobiology, Cell Biology
• The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53 AuthorsMadan E., Parker T. M., Bauer M. R., Dhiman A., Pelham C. J., Nagane M., Kuppusamy M. L., Holmes M., Holmes T. R., Shaik K., Shee K., Kiparoidze S., Smith S. D., Park Y. A., Gomm J., Jones L. J., Tomás A. R., Cunha A. C., Selvendiran K., Hansen L. A., Fersht A. R., Hideg K., Gogna R., Kuppusamy P. Journal Journal of Biological Chemistry 293(12):4262-4276. 23 March 2018 (2018)
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  DOI10.1074/jbc. RA117.000950 PMID29382728 PMCIDPMC5868245 DivisionProtein & Nucleic Acid Chemistry
• Substrate clustering potently regulates activity of WW-HECT domain-containing ubiquitin ligases AuthorsMund T., Pelham H. R. Journal Journal of Biological Chemistry 293(14):5200-5209. 20 February 2018 (2018)
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  DOI10.1074/jbc. RA117.000934 PMID29463679 PMCIDPMC5892558 DivisionCell Biology
• Disinhibition of the HECT E3 ubiquitin ligase WWP2 by polymerized Dishevelled AuthorsMund T., Graeb M., Mieszczanek J., Gammons M., Pelham H. R., Bienz M. Journal Open Biology 5(12). 23 December 2015 (2015)
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  DOI10.1098/rsob.150185 PMID26701932 PMCIDPMC4703060 DivisionProtein & Nucleic Acid Chemistry, Cell Biology
• Peptide and small molecule inhibitors of HECT-type ubiquitin ligases AuthorsMund T., Lewis M. J., Maslen S., Pelham H. R. Journal Proceedings of the National Academy of Sciences, USA 111(47):16736-16741. 25 November 2014 (2014)
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  DOI10.1073/pnas.1412152111 PMID25385595 PMCIDPMC4250122 DivisionCell Biology
• Building for the future AuthorsPelham H. Journal ELife 2:e00856. 28 May 2013 (2013)
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  DOI10.7554/eLife.00856 PMID23741620 PMCIDPMC3667621 DivisionCell Biology
• Regulation of PTEN/Akt and MAP kinase signaling pathways by the ubiquitin ligase activators Ndfip1 and Ndfip2 AuthorsMund T., Pelham H. R. Journal Proceedings of the National Academy of Sciences, USA 107(25):11429-11434. 22 June 2010 (2010)
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  DOI10.1073/pnas.0911714107 PMID20534535 PMCIDPMC2895104 DivisionCell Biology
• Arrestin-mediated endocytosis of yeast plasma membrane transporters. AuthorsNikko E., Pelham H. R. B. Journal Traffic 10(12): 1856-1857. December 2009 (2009)
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  DOI10.1111/j.1600-0854.2009.00990.x PMID19912579 PMCIDPMC2810449 DivisionCell Biology
• Inefficient quality control of thermosensitive proteins on the plasma membrane AuthorsLewis M. J., Pelham H. R. B. Journal PLoS One 4 (4): e5038. 1 April 2009 (2009)
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  DOI10.1371/journal.pone.0005038 PMID19337370 PMCIDPMC2659772 DivisionCell Biology
• Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteins AuthorsThomas Mund, Hugh R. B. Pelham Journal EMBO Reports 10(5):501-507 (2009) (2009)
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  DOI10.1038/embor.2009.30 PMID19343052 PMCID  DivisionCell Biology
• Arrestin-like proteins mediate ubiquitination and endocytosis of the yeast metal transporter Smf1 AuthorsElina Nikko, James A Sullivan, Hugh R B Pelham Journal EMBO Reports 9 (12): 1216-1221 (2008)
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  DOI  PMID18953286 PMCID PMC2575832 Division 
• Multiple interactions drive adaptor-mediated recruitment of the ubiquitin ligase Rsp5 to membrane proteins in vivo and in vitro AuthorsJames A. Sullivan, Michael J. Lewis, Elina Nikko, Hugh R. B. Pelham Journal Molecular Biology of the Cell 18(7): 2429-2440 (2007) (2007)
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• Transferrin receptor-like proteins control the degradation of a yeast metal transporter AuthorsStimpson H. E. M., Lewis M. J., Pelham H. R. B. Journal EMBO Journal 25(4):662-672. 22 February 2006 (2006 )
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  DOI10.1038/sj.emboj.7600984 PMID16456538 PMCIDPMC1383565 DivisionCell Biology
• Structural analysis of the interaction between the SNARE Tlg1 and Vps51 AuthorsFridmann-Sirkis Y., Kent H. M., Lewis M. J., Evans P. R., Pelham H. R. B. Journal Traffic 7(2):182-190. February 2006 (2006 )
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  DOI10.1111/j.1600-0854.2005.00374.x PMID16420526 PMCID  DivisionStructural Studies, Cell Biology
• Maturation of Golgi cisternae directly observed AuthorsHugh R. B. Pelham Journal Trends in Biochemical Sciences 31: 601-604 (2006) (2006)
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• Swf1-dependent palmitoylation of the SNARE Tlg1 prevents its ubiquitination and degradation AuthorsJavier Valdez-Taubas, Hugh Pelham Journal EMBO Journal 24 : 2542-5232 (2005) (2005)
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• TMF is a golgin that binds Rab6 and influences Golgi morphology AuthorsFridmann-Sirkis Y., Siniossoglou S., Pelham H. R. B. Journal BMC Cell Biology 5: 18 (pp.1-9). 5 May 2004 (2004)
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  DOI10.1186/1471-2121-5‑18 PMID15128430 PMCIDPMC419336 DivisionCell Biology
• Membrane traffic: GGAs sort ubiquitin AuthorsPelham H. R. B. Journal Current Biology 14(9):R357-9. 4 May 2004 (2004)
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  DOI10.1016/j. Cub.2004.04.027 PMID15120092 PMCID  DivisionCell Biology
• Bsd2 binds the ubiquitin ligase Rsp5 and mediates the ubiquitination of transmembrane proteins AuthorsHettema E. H., Valdez-Taubas J., Pelham H. R. B. Journal EMBO Journal 23(6):1279-1288 (2004) (2004)
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  DOI10.1038/sj.emboj.7600137 PMID14988731 PMCIDPMC381411 DivisionCell Biology
• Slow diffusion of proteins in the yeast plasma membrane allows polarity to be maintained by endocytic cycling AuthorsValdez-Taubas J., Pelham H. R. B. Journal Current Biology 13(18):1636-1640. 16 September 2003 (2003)
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  DOI10.1016/j. Cub.2003.09.001 PMID13678596 PMCID  DivisionCell Biology
• Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomes AuthorsHettema E. H., Lewis M. J., Black M. W., Pelham H. R. B. Journal EMBO Journal 22(3):548-557. 3 February 2003 (2003)
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  DOI10.1093/emboj/cdg062 PMID12554655 PMCIDPMC140746 DivisionCell Biology
• Vps51p links the VFT complex to the SNARE Tlg1p AuthorsSiniossoglou S., Pelham H. R. B. Journal Journal of Biological Chemistry 277(50):48318-48324. 13 December 2002 (2002)
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  DOI10.1074/jbc.m209428200 PMID12377769 PMCID  DivisionCell Biology
• A new yeast endosomal SNARE related to mammalian syntaxin 8 AuthorsLewis M. J., Pelham H. R. B. Journal Traffic 3(12):922-929. December 2002 (2002)
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  DOI10.1034/j.1600-0854.2002.31207.x PMID12453154 PMCID  DivisionCell Biology
• Insights from yeast endosomes AuthorsPelham H. R. B. Journal Current Opinion in Cell Biology 14(4):454-462. 1 August 2002 (2002)
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  DOI10.1016/s0955-0674(02)00352-6 PMID12383796 PMCID  DivisionCell Biology
• A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies AuthorsReggiori F., Pelham H. R. B. Journal Nature Cell Biology 4(2):117-123. February 2002 (2002)
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  DOI10.1038/ncb743 PMID11788821 PMCID  DivisionCell Biology
• Traffic through the Golgi apparatus AuthorsPelham H. R. B. Journal Journal of Cell Biology 155(7):1099-1101. 24 December 2001 (2001)
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  DOI10.1083/jcb.200110160 PMID11756463 PMCIDPMC2199341 DivisionCell Biology
• An effector of Ypt6p binds the SNARE Tlg1p and mediates selective fusion of vesicles with late golgi membranes AuthorsSiniossoglou S., Pelham H. R. B. Journal EMBO Journal 20(21):5991-5998 (2001) (2001)
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  DOI10.1093/emboj/20.21.5991 PMID11689439 PMCIDPMC125711 DivisionCell Biology
• Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting AuthorsReggiori F., Pelham H. R. B. Journal EMBO Journal 20(18):5176-5186 (2001) (2001)
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  DOI10.1093/emboj/20.18.5176 PMID11566881 PMCIDPMC125630 DivisionCell Biology
• Membrane traffic: How do GGAs fit in with the adaptors? AuthorsBlack M. W., Pelham H. R. B. Journal Current Biology 11(12):R460-2 (2001) (2001)
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  DOI10.1016/S0960-9822(01)00281‑0 PMID11448785 PMCID  DivisionCell Biology
• SNAREs and the specificity of membrane fusion AuthorsPelham H. R B. Journal Trends in Cell Biology 11(3):99-101 (2001) (2001)
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  DOI10.1016/S0962-8924(01)01929‑8 PMID11306253 PMCID  DivisionCell Biology
• The debate about transport in the Golgi - two sides of the same coin? AuthorsPelham H. R. B., Rothman J. E. Journal Cell 102(6):713-719. 15 September 2000 (2000)
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  DOI10.1016/s0092-8674(00)00060‑x PMID11030615 PMCID  DivisionCell Biology
• Psr1p/Psr2p, two plasma membrane phosphatases with an essential DXDX(T/V) motif required for sodium stress response in yeast AuthorsSiniossoglou S., Hurt E. C., Pelham H. R. B. Journal Journal of Biological Chemistry 275(25):19352-19360 (2000) (2000)
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  DOI10.1074/jbc.m001314200 PMID10777497 PMCID  DivisionCell Biology
• Getting stuck in the Golgi AuthorsPelham H. Journal Traffic 1(2):191-192 (2000) (2000)
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  DOI10.1034/j.1600-0854.2000.010213.x PMID11208101 PMCID  DivisionCell Biology
• Polar transmembrane domains target proteins to the interior of the yeast vacuole AuthorsFulvio Reggiori, Michael W. Black, Hugh R. B. Pelham Journal Molecular Biology of the Cell 11: 3737-3749 (2000) (2000)
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• A selective transport route from golgi to late endosomes that requires the yeast GGA proteins AuthorsMichael W. Black, Hugh R. B. Pelham Journal Journal of Cell Biology 151: 587-600 (2000) (2000)
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• Ric1p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6p AuthorsSymeon Siniossoglou, Sew Y. Peak-Chew, Hugh R. B. Pelham Journal EMBO Journal 19: 4885-4894 (2000) (2000)
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• Specific retrieval of the exocytic SNARE Snc1p from early yeast endosomes AuthorsLewis M. J., Nichols B. J., Prescianotto-Baschong C., Riezman H.,Pelham H. R. B. Journal Molecular Biology of the Cell 11(1):23-38 (2000) (2000)
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  DOI10.1091/mbc.11.1.23 PMID10637288 PMCIDPMC14754 DivisionCell Biology
• The Croonian Lecture 1999. Intracellular membrane traffic: getting proteins sorted AuthorsPelham H. R. B. Journal Phil. Trans. R. Soc. Lond. B. 354(1388):1471-1478 (1999) (1999)
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  DOI10.1098/rstb.1999.0491 PMID10515003 PMCIDPMC1692657 Division 
• Got1p and Sft2p: membrane proteins involved in traffic to the Golgi complex AuthorsConchon S., Cao X., Barlowe C., Pelham H. R. B. Journal EMBO Journal 18(14):3934-3946 (1999) (1999)
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  DOI10.1093/emboj/18.14.3934 PMID10406798 PMCIDPMC1171469 DivisionCell Biology
• SNAREs and the secretory pathway - lessons from yeast AuthorsPelham H. R. B. Journal Experimental Cell Research 247(1):1-8 (1999) (1999)
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  DOI10.1006/excr.1998.4356 PMID10047442 PMCID  Division 
• The Sec1p homologue Vps45p binds to the syntaxin Tlg2p AuthorsNichols B. J., Holthuis J. C. M., Pelham H. R. B. Journal European Journal of Cell Biology 77(4):263-268. December 1998 (1998)
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  DOI10.1016/S0171-9335(98)80084-8 PMID9930650 PMCID  DivisionCell Biology
• The dynamics of Golgi protein traffic visualized in living yeast cells AuthorsWooding S., Pelham H. R. B. Journal Molecular Biology of the Cell 9(9):2667-2680. September 1998 (1998)
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  DOI10.1091/mbc.9.9.2667 PMID9725919 PMCIDPMC25539 DivisionCell Biology
• Identification of amino acids in the binding pocket of the human KDEL receptor AuthorsScheel, A. A., Pelham, H. R. B. Journal Journal of Biological Chemistry 273(4):2467-2472. 23 January 1998 (1998)
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  DOI10.1074/jbc.273.4.2467 PMID9442098 PMCID  DivisionCell Biology
• Two syntaxin homologues in the TGN/endosomal system of yeast AuthorsJoost C. M. Holthuis, Benjamin J. Nichols, Sadhana Dhruvakumar, Hugh R. B. Pelham Journal EMBO Journal 17: 113-126 (1998) (1998)
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• Getting through the Golgi complex AuthorsHugh R. B. Pelham Journal Trends in Cell Biology 8: 45-49 (1998) (1998)
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• A vacuolar v-t-SNARE complex, the predominant form in vivo and on isolated vacuoles, is disassembled and activated for docking and fusion AuthorsChristian Ungermann, Benjamin J. Nichols, Hugh R. B. Pelham, William Wickner Journal Journal of Cell Biology 140: 61-69 (1998) (1998)
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• SNAREs and membrane fusion in the Golgi apparatus AuthorsBenjamin J. Nichols, Hugh R. B. Pelham Journal Biochimica et Biophysica Acta (BBA) 1404: 9-31 (1998) (1998)
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• The syntaxinT1g1p mediates trafficking of chitin synthase III to polarized growth sites in yeast AuthorsJoost C. M. Holthuis, Benjamin J. Nichols, Hugh R. B. Pelham Journal Molecular Biology of the Cell 9: 3383-3397 (1998) (1998)
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• Transmembrane domain-dependent sorting of proteins to the ER and plasma membrane in yeast AuthorsJulian C. Rayner, Hugh R. B. Pelham Journal EMBO Journal 16(8):1832-1841. 15 April 1997 (1997)
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  DOI10.1093/emboj/16.8.1832 PMID9155009 PMCIDPMC1169786 DivisionCell Biology
• Homotypic vacuolar fusion mediated by t- and v‑SNAREs AuthorsBenjamin J. Nichols, Christian Ungermann, Hugh R. B. Pelham, William T. Wickner, Albert Haas Journal Nature 387: 199-202 (1997) (1997)
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• SNAREs and the organization of the secretory pathway AuthorsHugh R. B. Pelham Journal European Journal of Cell Biology 74(4):311-314 (1997) (1997)
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  DOI  PMID9438125 PMCID  Division 
• Purification and characterization of the human KDEL receptor AuthorsScheel A. A., Pelham H. R. B. Journal Biochemistry 35(31):10203-10209. 6 August 1996 (1996)
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  DOI10.1021/bi960807x PMID8756485 PMCID  DivisionCell Biology
• SNARE-mediated retrograde traffic from the Golgi complex to the endoplasmic reticulum AuthorsMichael J. Lewis, Hugh R. B. Pelham Journal Cell 85: 205-215 (1996) (1996)
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• The dynamic organisation of the secretory pathway AuthorsHugh R. B. Pelham Journal Cell Structure and Function 21: 413-419 (1996) (1996)
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• A SNARE-like protein required for traffic through the Golgi complex AuthorsDavid K. Banfield, Michael J. Lewis, Hugh R. B. Pelham Journal Nature 375: 806-809 (1995) (1995)
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• Sorting and retrieval between the endoplasmic reticulum and Golgi apparatus AuthorsHugh R. B. Pelham Journal Current Opinion in Cell Biology 7: 530-535 (1995) (1995)
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• SNAREs involved in traffic through the Golgi complex AuthorsH. R. B. Pelham, D. K. Banfield, M. J. Lewis Journal Cold Spring Harbor Symposia on Quantitative Biology LX: 105-111 (1995) (1995)
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• The KKXX signal mediates retrieval of membrane proteins from the Golgi to the ER in yeast AuthorsTownsley F. M., Pelham H. R. B. Journal European Journal of Cell Biology 64(1):211-216. June 1994 (1994)
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  DOI  PMID7957309 PMCID  DivisionCell Biology
• SED6 is identical to ERG6, and encodes a putative methyltransferase required for ergosterol synthesis AuthorsHardwick K. G., Pelham H. R. B. Journal Yeast 10(2):265-269 (1994) (1994)
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  DOI10.1002/yea.320100213 PMID8203167 PMCID  DivisionCell Biology
• Localization of Sed5, a putative vesicle targeting molecule, to the cis-Golgi network involves both its transmembrane and cytoplasmic domains AuthorsDavid K. Banfield, Michael J. Lewis, Catherine Rabouille, Graham Warren, Hugh R. B. Pelham Journal Journal of Cell Biology 127: 357-371 (1994) (1994)
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• Retrieval of HDEL proteins is required for growth of yeast cells AuthorsFiona M. Townsley, Gabriella Frigerio, Hugh R. B. Pelham Journal Journal of Cell Biology 127: 21-28 (1994) (1994)
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• Sorting of membrane proteins in the secretory pathway AuthorsPelham H. R., Munro S. Journal Cell 75(4):603-605. 19 November 1993 (1993)
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  DOI10.1016/0092-8674(93)90479‑A PMID8242736 PMCID  DivisionCell Biology
• Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport AuthorsTownsley F. M., Wilson D. W., Pelham H. R. B. Journal EMBO Journal 12: 2821-2829. 1 July 1993 (1993)
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  DOI10.1002/j.1460-2075.1993.tb05943.x PMID8392934 PMCIDPMC413532 DivisionCell Biology
• pH-dependent binding of KDEL to its receptor in vitro AuthorsDuncan W. Wilson, Michael J. Lewis, Hugh R. B. Pelham Journal Journal of Biological Chemistry 268: 7465-7468 (1993) (1993)
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• A Saccharomyces cerevisiae cyclophilin resident in the endoplasmic reticulum AuthorsG. Frigerio, H. R. B. Pelham Journal Journal of Molecular Biology 233: 183-188 (1993) (1993)
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• The TIP1 gene in Saccharomyces cerevisiae encodes an 80 kDa cytoplasmic protein that interacts with the cytoplasmic domin of Sec20p Authors Deborah J. Sweet, Hugh R. B. Pelham Journal EMBO Journal 12: 2831-2840 (1993) (1993)
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• The Florey Lecture, 1992. The secretion of proteins by cells AuthorsPelham H. R. B. Journal Proceedings. Biological Sciences 250(1327):1-10. 22 October 1992 (1992)
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  DOI10.1098/rspb.1992.0123 PMID1334264 PMCID  DivisionCell Biology
• Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum AuthorsMichael J. Lewis, Hugh R. B. Pelham Journal Cell 68: 353-364 (1992) (1992)
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• Changing the specificity of the sorting receptor for luminal endoplasmic reticulum proteins AuthorsJan C. Semenza, Hugh R. B. Pelham Journal Journal of Molecular Biology 224: 1-5 (1992) (1992)
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• The Saccharomyces cerevisiae SEC20 gene encodes a membrane glycoprotein which is sorted by the HDEL retrieval system AuthorsDeborah J. Sweet, Hugh R. B. Pelham Journal EMBO Journal 11: 423-432 (1992) (1992)
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• Toxin entry: how reversible is the secretory pathway? AuthorsHugh R. B. Pelham, Lynne M. Roberts, J. Michael Lord Journal Trends in Cell Biology 2: 183-185 (1992) (1992)
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• Genes that allow yeast cells to grow in the absence of the HDEL receptor AuthorsKevin G. Hardwick, John C. Boothroyd, Adam D. Rudner, Hugh R. B. Pelham Journal EMBO Journal 11: 4187-4195 (1992) (1992)
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• SED5 encodes a 39-kD integral membrane protein required for the vesicular transport between the ER and the Golgi complex AuthorsKevin G. Hardwick, Hugh R. B. Pelham Journal Journal of Cell Biology 119: 513-521 (1992) (1992)
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• Sequence of a second human KDEL receptor AuthorsMichael J. Lewis, Hugh R. B. Pelham Journal Journal of Molecular Biology 226: 913-916 (1992) (1992)
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• Immunological evidence that plants use both HDEL and KDEL for targeting proteins to the endoplasmic reticulum AuthorsRichard M. Napier, Larry C. Fowke, Chris Hawes, Mike Lewis, Hugh R. B. Pelham Journal Journal of Cell Science 102: 261-271 (1992) (1992)
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• A conserved heptapeptide restrains the activity of the yeast heat shock transcription factor AuthorsBent K. Jakobsen, Hugh R. B. Pelham Journal EMBO Journal 10: 369-375 (1991) (1991)
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• Multiple targets for brefeldin A AuthorsHugh R. B. Pelham Journal Cell 67: 449-451 (1991 ) (1991)
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• The retention signal for soluble proteins of the endoplasmic reticulum AuthorsPelham H. R. B. Journal Trends in Biochemical Sciences 15(12):483-486. December 1990 (1990)
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  DOI10.1016/0968-0004(90)90303-s PMID2077689 PMCID  DivisionCell Biology
• Recycling of proteins from the golgi compartment to the ER in yeast AuthorsNeta Dean N., Pelham H. R. B. Journal Journal of Cell Biology 111(2):369-377. 1 August 1990 (1990)
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  DOI10.1083/jcb.111.2.369 PMID2199456 PMCIDPMC2116185 DivisionCell Biology
• The ERD2 gene determines the specificity of the luminal ER protein retention system AuthorsLewis M. J., Sweet D. J., Pelham H. R. B. Journal Cell 61(7):1359-1363. 29 June 1990 (1990)
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  DOI10.1016/0092-8674(90)90699‑F PMID2194671 PMCID  DivisionCell Biology
• ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway AuthorsSemenza J. C., Hardwick K. G., Dean N., Pelham H. R. B. Journal Cell 61(7):1349-1357. 29 June 1990 (1990)
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  DOI10.1016/0092-8674(90)90698‑E PMID2194670 PMCID  DivisionCell Biology
• ERS1 a seven transmembrane domain protein from Saccharomyces cerevisiae AuthorsHardwick K. G., Pelham H. R. Journal Nucleic Acids Research 18(8):2177. 25 April 1990 (1990)
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  DOI10.1093/nar/18.8.2177 PMID2186379 PMCIDPMC330704 DivisionCell Biology
• ERD1, a yeast gene required for the retention of luminal endoplasmic reticulum proteins, affects glycoprotein processing in the Golgi apparatus AuthorsHardwick K. G., Lewis M. J., Semenza J., Dean N., Pelham H. R. B. Journal EMBO Journal 9(3):623-30. March 1990 (1990)
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  DOI10.1002/j.1460-2075.1990.tb08154.x PMID2178921 PMCIDPMC551715 DivisionCell Biology
• The sequence of the Kluyveromyces lactis BiP gene AuthorsM. J. Lewis, H. R. B. Pelham Journal Nucleic Acids Research 18: 6438 (1990) (1990)
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• A human homologue of the yeast HDEL receptor AuthorsMichael J. Lewis, Hugh R. B. Pelham Journal Nature 348: 162-163 (1990) (1990)
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• Functions of the hsp70 protein family: an overview AuthorsPelham H. R. B. Journal Stress Proteins in Biology and Medicine. Cold Spring Harbor Laboratory Press pp.287-299 (1990) (1990)
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• The sorting of resident ER proteins from secreted proteins AuthorsHugh R. B. Pelham Journal The Robert A. Welch Foundation Conference on Chemical Research. XXXIII Membrane Proteins: Targeting and Transduction pp.35-50 (1989) (1989)
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• Control of protein exit from the endoplasmic reticulum AuthorsHugh R. B. Pelham Journal Annu. Rev. Cell Biol. 5: 1-23 (1989) (1989)
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• Heat shock and the sorting of luminal ER proteins AuthorsHugh R. B. Pelham Journal EMBO Journal 8: 3171-3176 (1989) (1989)
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• The selectivity of secretion: protein sorting in the endoplasmic reticulum. (Twenty-sixth Colworth Medal Lecture) AuthorsHugh R. B. Pelham Journal Biochemical Society Transactions 17: 795-802 (1989) (1989)
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• Evidence that luminal ER proteins are sorted from secreted proteins in a post-ER compartment AuthorsPelham H. R. B. Journal EMBO Journal 7(4):913-918. 1 April 1988 (1988)
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  DOI10.1002/j.1460-2075.1988.tb02896.x PMID3402439 PMCIDPMC454416 DivisionCell Biology
• Heat-shock proteins. Coming in from the cold AuthorsHugh Pelham Journal Nature 332: 776-777 (1988) (1988)
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• Seventy-kilodalton heat shock proteins and an additional component from reticulocyte lysate stimulate import of M13 procoat protein into microsomes AuthorsRichard Zimmermann, Maria Sagstetter, Michael J. Lewis, Hugh R. B. Pelham Journal EMBO Journal 7: 2875-2880 (1988) (1988)
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• Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phoshorylation AuthorsPeter K. Sorger, Hugh R. B. Pelham Journal Cell 54: 855-864 (1988) (1988)
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• Constitutive binding of yeast heat shock factor to DNA in vivo AuthorsBent K. Jakobsen, Hugh R. B. Pelham Journal Molecular and Cellular Biology 8: 5040-5042 (1988) (1988)
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• Sorting of soluble ER proteins in yeast AuthorsHugh R. B. Pelham, Kevin G. Hardwick, Michael J. Lewis Journal EMBO Journal 7: 1757-1762 (1988) (1988)
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• An ecdysone response element in the Drosophila hsp27 promoter AuthorsRiddihough G., Pelham H. R. B. Journal EMBO Journal 6(12):3729-3734. 1 December 1987 (1987)
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  DOI10.1002/j.1460-2075.1987.tb02707.x PMID16453813 PMCIDPMC553843 DivisionCell Biology
• Heat shock factor is regulated differently in yeast and HeLa cells AuthorsSorger P. K., Lewis M. J., Pelham H. R. B. Journal Nature 329(6134):81-84. 3 September 1987 (1987)
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  DOI10.1038/329081a0 PMID3306402 PMCID  DivisionCell Biology
• Properties and uses of heat shock promoters AuthorsHugh Pelham Journal Genetic Engineering, Vol. 9. Edited by Jane K. Setlow pp.27-44 (1987) (1987)
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• Cloning and expression of a gene encoding hsc73, the major hsp70-like protein in unstressed rat cells AuthorsPeter K. Sorger, Hugh R. B. Pelham Journal EMBO Journal 6: 993-998 (1987) (1987)
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• The glucose-regulated protein grp94 is related to heat shock protein hsp90 AuthorsPeter K. Sorger, Hugh R. B. Pelham Journal Journal of Molecular Biology 194: 341-344 (1987) (1987)
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• Purification and characterization of a heat-shock element binding protein from yeast AuthorsPeter K. Sorger, Hugh R. B. Pelham Journal EMBO Journal 6: 3035-3041 (1987) (1987)
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• A C-terminal signal prevents secretion of luminal ER proteins AuthorsSean Munro, Hugh R. B. Pelham Journal Cell 48: 899-907 (1987) (1987)
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• Speculations on the functions of the major heat shock and glucose-regulated proteins AuthorsPelham H. R. B. Journal Cell 46(7):959-961. 26 September 1986 (1986)
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  DOI10.1016/0092-8674(86)90693‑8 PMID2944601 PMCID  DivisionCell Biology
• An hsp7O-like protein in the ER: identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein AuthorsMunro S., Pelham H. R. B. Journal Cell 46(2):291-300. 18 July 1986 (1986)
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  DOI10.1016/0092-8674(86)90746-4 PMID3087629 PMCID  DivisionCell Biology
• Activation of the Drosophila hsp27 promoter by heat shock and by ecdysone involves independent and remote regulatory sequences AuthorsRiddihough G., Pelham H. R. B. Journal EMBO Journal 5(7):1653-1658. 1 July 1986 (1986)
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  DOI10.1002/j.1460-2075.1986.tb04408.x PMID16453691 PMCIDPMC1166991 DivisionCell Biology
• Heat shock regulatory elements function as an inducible enhancer in the Xenopus hsp70 gene and when linked to a heterologous promoter AuthorsBienz M., Pelham H. R. B. Journal Cell 45(5):753-760. 6 June 1986 (1986)
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  DOI10.1016/0092-8674(86)90789‑0 PMID3085957 PMCID  DivisionProtein & Nucleic Acid Chemistry, Cell Biology
• Activation of heat-shock genes in eukaryotes AuthorsHugh Pelham Journal Trends in Genetics 1: 31-35 (1985) (1985)
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• A nucleolar function for mammalian and Drosophila 7OkD heat shock proteins AuthorsHugh Pelham, Michael Lewis, Sean Munro Journal Sequence Specificity in Transcription and Translation. Alan R. Liss, Inc. pp 681-688 (1985) (1985)
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• What turns on heat shock genes? AuthorsSean Munro, Hugh Pelham Journal Nature 317: 477-478 (1985) (1985)
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• Involvement of ATP in the nuclear and nucleolar functions of the 70 kd heat shock protein AuthorsMichael J. Lewis, Hugh R. B. Pelham Journal EMBO Journal 4: 3137-3143 (1985) (1985)
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• The use of promoter fusions in Drosophila genetics: isolation of mutations affecting the heat shock response AuthorsJ. Jose Bonner, Carol Parks, Janice Parker-Thornburg, Mark A. Mortin, Hugh R. B. Pelham Journal Cell 37: 979-991 (1984) (1984)
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• Expression of a Drosophila heat shock protein in mammalian cells: transient association with nucleoli after heat shock AuthorsH. Pelham, M. Lewis, Susan Lindquist Journal Phil. Trans. R. Soc. Lond. B 307: 301-307 (1984) (1984)
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• Hsp70 accelerates the recovery of nucleolar morphology after heat shock AuthorsHugh R. B. Pelham Journal EMBO Journal 3: 3095-3100 (1984) (1984)
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• Use of peptide tagging to detect proteins expressed from cloned genes: deletion mapping functional domains of Drosophila hsp70 AuthorsSean Munro, Hugh R. B. Pelham Journal EMBO Journal 3: 3087-3093 (1984) (1984)
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• The use of promoter fusions in Drosophila genetics: isolation of mutations affecting the heat shock response AuthorsJ. Jose Bonner, Carol Parks, Janice Parker-Thornburg, Mark A. Mortin, Hugh R. B. Pelham Journal Cell 37: 979-991 (1984) (1984)
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• Use of peptide tagging to detect proteins expressed from cloned genes: deletion mapping functional domains of Drosophila hsp70 AuthorsSean Munro, Hugh R. B. Pelham Journal EMBO Journal 3: 3087-3093 (1984) (1984)
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• Association of an S1 nuclease-sensitive structure with short direct repeats 5' of Drosophila heat shock genes AuthorsMace H. A. F., Pelham H. R. B., Travers A. A. Journal Nature 304(5926):555-557 (1983) (1983)
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  DOI10.1038/304555a0 PMID6308469 PMCID  DivisionCell Biology
• Assay of natural and synthetic heat-shock promoters in monkey COS cells: requirements for regulation AuthorsHugh R. B. Pelham, Michael J. Lewis Journal Gene Expression. Alan R. Liss, Inc. pp.75-85 (1983) (1983)
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• Expression of a Drosophila heat-shock protein in Xenopus oocytes: conserved and divergent regulatory signals AuthorsBienz, M., Pelham, H.R. Journal The EMBO Journal 1(12):1583-1588 (1982)
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• A synthetic heat-shock promoter element confers heat-inducibility on the herpes simplex virus thymidine kinase gene AuthorsPelham, H.R., Bienz, M. Journal The EMBO Journal 1(11):1473-1477 (1982)
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  DOIdoi.org/10.1002/j.1460-2075.1982.tb01340.x PMID6327271 PMCIDPMC553234 Division 
• A regulatory upstream promoter element in the Drosophila Hsp 70 heat-shock gene AuthorsHugh R. B. Pelham Journal Cell 30: 517-528 (1982) (1982)
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• DNA sequences required for transcriptional regulation of the Drosophila hsp70 heat-shock gene in monkey cells and Xenopus oocytes AuthorsHugh Pelham, Mariann Bienz Journal Heat Shock from Bacteria to Man. Edited by M. J. Schlesinger, M. Ashburner, A. Tissieres pp.43-48 (1982) (1982)
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