Published Research
Found 232 results for McKenzie.
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IL-25 enhances B cell responses in type 2 inflammation through IL-17RB receptor
AuthorsAbdu S., Xia J., Yuan H., Ju Tan T., Layhadi J. A., Shamji M. H., McKenzie A. N. J., Haloob N., Hopkins C., Woszczek G., Till S. J.
Journal
Allergy
80(4):965-975 (2025)
Details
DOIdoi.org/10.1111/all.16472 PMID39829150 PMCIDPMC11969324 DivisionProtein & Nucleic Acid Chemistry - Molecular mechanisms regulating T helper 2 cell differentiation and function AuthorsSzeto A. C., Ferreira A. C., McKenzie A. N. Journal Current Opinion in Immunology 91:102483 (2024)
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Recipient tissue microenvironment determines developmental path of intestinal innate lymphoid progenitors
AuthorsClark P. A., Gogoi M., Rodriguez-Rodriguez N., Ferreira A. C. F., Murphy J. E., Walker J. A., Crisp A., Jolin H. E., Shields J. D., McKenzie A. N. J.
Journal
Nature Communications
15(1):7809 (2024)
Details
DOI10.1038/s41467-024-52155‑2 PMID39242588 PMCIDPMC11379955 DivisionProtein & Nucleic Acid Chemistry -
ILC2-derived LIF licences progress from tissue to systemic immunity
AuthorsGogoi M., Clark P. A., Ferreira A. C. F., Rodriguez Rodriguez N., Heycock M., Ko M., Murphy J. E., Chen V., Luan S. L., Jolin H. E., McKenzie A. N. J.
Journal
Nature
632(8026):885-892 (2024)
Details
DOIdoi.org/10.1038/s41586-024-07746-w PMID39112698 PMCIDPMC11338826 DivisionProtein & Nucleic Acid Chemistry - Cross-talk between ILC2 and Gata3high Tregs locally constrains adaptive type 2 immunity AuthorsStockis J, Yip T, Moreno-Vicente J, Burton O, Samarakoon Y, Schuijs MJ, Raghunathan S, Garcia C, Luo W, Whiteside SK, Png S, Simpson C, Monk S, Sawle A, Yin K, Barbieri J, Papadopoulos P, Wong H, Rodewald HR, Vyse T, McKenzie ANJ, Cragg MS, Hoare M, Withers DR, Fehling HJ, Roychoudhuri R, Liston A, Halim TYF. Journal Science Immunology Jul 19;9(97):eadl1903 (2024)
- Mef2d potentiates type-2 immune responses and allergic lung inflammation AuthorsSzeto ACH, Clark PA, Ferreira ACF, Heycock M, Griffiths EL, Jou E, Mannion J, Luan SL, Storrar S, Knolle MD, Kozik P, Jolin HE, Fallon PG, McKenzie ANJ. Journal Science Science. 2024 Jun 28;384(6703):eadl0370. doi: 10.1126/science. Adl0370. Epub 2024 Jun 28. (2024)
- Cooperation of ILC2s and T(H)2 cells in the expulsion of intestinal helminth parasites AuthorsZaiss D. M. W., Pearce E. J., Artis D., McKenzie A. N. J., Klose C. S. N. Journal Nature reviews. Immunology (2023)
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Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation
AuthorsFerreira A. C. F., Szeto A. C. H., Clark P. A., Crisp A., Kozik P., Jolin H. E., McKenzie A. N. J.
Journal
Immunity
56(7):1468-1484.e7 (2023)
Details
DOIdoi.org/10.1016/j.immuni.2023.05.010 PMID37285842 PMCIDPMC10501989 DivisionProtein & Nucleic Acid Chemistry -
Group 2 innate lymphoid cells protect mouse heart from myocardial infarction injury via interleukin 5, eosinophils, and dendritic cells
AuthorsLiu T., Meng Z., Liu J., Li J., Zhang Y., Deng Z., Luo S., Wang M., Huang Q., Zhang S., Fendt P., Devouassoux J., Li D., McKenzie A. N. J., Nahrendorf M., Libby P., Guo J., Shi G. P.
Journal
Cardiovascular Research
119(4):1046-1061 (2023)
Details
DOI 10.1093/cvr/cvac144 PMID36063432 PMCIDPMC10153644 DivisionProtein & Nucleic Acid Chemistry -
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils
AuthorsZhang Y, Liu T, Deng Z, Fang W, Zhang X, Zhang S, Wang M, Luo S, Meng Z, Liu J, Sukhova GK, Li D, McKenzie ANJ, Libby P, Shi GP, Guo J.
Journal
Advanced Science
10(7):e2206958 (2023)
Details
DOI10.1002/advs.202206958 PMID36592421 PMCIDPMC9982556 DivisionProtein & Nucleic Acid Chemistry -
An ฮฑvฮฒ3 integrin checkpoint is critical for efficient T(H)2 cell cytokine polarization and potentiation of antigen-specific immunity
AuthorsSzeto A.C.H., Ferreira A.C.F., Mannion J., Clark P.A., Sivasubramaniam M., Heycock M.W.D., Crisp A., Jolin H.E., Kozik P., Knolle M.D., McKenzie A.N.J.
Journal
Nature Immunology
24(1):123-135 (2022)
Details
DOI10.1038/s41590-022-01378‑w PMID36550322 PMCIDPMC7614022 DivisionProtein & Nucleic Acid Chemistry -
PU.1-driven Th9 cells promote colorectal cancer in experimental colitis models through IL-6 effects in intestinal epithelial cells
AuthorsGerlach K., Popp V., Wirtz S., Al-Saifi R., Gonzalez Acera M., Atreya R., Dregelis T., Vieth M., Fichtner-Feigl S., McKenzie A.N.J., Rosenbauer F., Weigmann B., Neurath M.F.
Journal
Journal of Crohn's & Colitis
16(12):1893-1910 (2022)
Details
DOI10.1093/ecco-jcc/jjac097 PMID35793807 PMCIDPMC10197880 DivisionProtein & Nucleic Acid Chemistry -
Identification of aceNKPs, a committed common progenitor population of the ILC1 and NK cell continuum
AuthorsRodriguez-Rodriguez N., Clark P.A., Gogoi M., Ferreira A.C.F., Kerscher B., Crisp A., Jolin H.E., Murphy J.E., Sivasubramaniam M., Pedro L., Walker J.A., Heycock M.W.D., Shields J.D., Barlow J.L., McKenzie A.N.J.
Journal
Proceedings of the National Academy of Sciences of the USA
119(49):e2203454119 (2022)
Details
DOI10.1073/pnas.2203454119 PMID36442116 PMCIDPMC7614094 DivisionProtein & Nucleic Acid Chemistry -
Emerging roles for IL-25 and IL-33 in colorectal cancer tumorigenesis
AuthorsJou E, Rodriguez-Rodriguez N, McKenzie ANJ.
Journal
Frontiers in Immunology
Oct 3;13:981479 (2022)
Details
DOI10.3389/fimmu.2022.981479 PMID36263033 PMCIDPMC9573978 DivisionProtein & Nucleic Acid Chemistry -
Group 2 innate lymphoid cells protect mouse heart from myocardial infarction injury via interleukin 5, eosinophils, and dendritic cells
AuthorsLiu T., Meng Z., Liu J., Li J., Zhang Y., Deng Z., Luo S., Wang M., Huang Q., Zhang S., Fendt P., Devouassoux J., Li D., McKenzie A.N.J., Nahrendorf M., Libby P., Guo J., Shi G.P.
Journal
Cardiovascular Research
119(4):1046-1061 (2022)
Details
DOI10.1093/cvr/cvac144 PMID36063432 PMCIDPMC10153644 DivisionProtein & Nucleic Acid Chemistry -
An innate IL-25-ILC2-MDSC axis creates a cancer-permissive microenvironment for Apc mutation-driven intestinal tumorigenesis
AuthorsJou E, Rodriguez-Rodriguez N, Ferreira AF, Jolin HE, Clark PA, Sawmynaden K, Ko M, Murphy JE, Mannion J, Ward C, Matthews DJ, Buczacki SJA, McKenzie ANJ.
Journal
Science Immunology
Jun 3;7(72):eabn0175 (2022)
Details
DOI10.1126/sciimmunol. Abn0175 PMID35658010 PMCIDPMC7612821 DivisionProtein & Nucleic Acid Chemistry -
Targeting TLR4 during vaccination boosts MAdCAM-1+ lymphoid stromal cell activation and promotes the aged germinal center response
AuthorsDenton A.E., Dooley J., Cinti I., Silva-Cayetano A., Fra-Bido S., Innocentin S., Hill D.L., Carr E. J., McKenzie A.N.J., Liston A., Linterman M.A.
Journal
Science Immunology
7(71):eabk0018 (2022)
Details
DOI10.1126/sciimmunol. Abk0018 PMID35522725 PMCIDPMC7612953 DivisionProtein & Nucleic Acid Chemistry -
Eosinophils are an essential element of a type 2 immune axis that controls thymus regeneration
AuthorsCosway E. J., White A. J., Parnell S. M., Schweighoffer E., Jolin H. E., Bacon A., Rodewald H. R., Tybulewicz V., McKenzie A. N. J., Jenkinson W. E., Anderson G.
Journal
Science Immunology
7(69):eabn3286 (2022)
Details
DOI10.1126/sciimmunol. Abn3286 PMID35275754 PMCIDPMC7612579 DivisionProtein & Nucleic Acid Chemistry -
Viral PB1-F2 and host IFN-ฮณ guide ILC2 and T cell activity during influenza virus infection
AuthorsBarman T. K., Huber V. C., Bonin J. L., Califano D., Salmon S. L., McKenzie A. N. J., Metzger D. W.
Journal
Proceedings of the National Academy of Sciences of the United States of America
119(8):e2118535119 (2022)
Details
DOI10.1073/pnas.2118535119 PMID35169077 PMCIDPMC8872759 DivisionProtein & Nucleic Acid Chemistry - IL-33-ILC2 axis represents a potential adjuvant target to increase the cross-protective efficacy of influenza vaccine AuthorsWilliams C. M., Roy S., Califano D., McKenzie A. N. J., Metzger D. W., Furuya Y. Journal Journal of Virology 95(22):e0059821 (2021)
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SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation
AuthorsBidault G., Virtue S., Petkevicius K., Jolin H. E., Dugourd A., Guรฉnantin A. C., Leggat J., Mahler-Araujo B., Lam B. Y. H., Ma M. K., Dale M., Carobbio S., Kaser A., Fallon P. G., Saez-Rodriguez J., McKenzie A. N. J., Vidal-Puig A.
Journal
Nature Metabolism
3(9):1150-1162 (2021)
Details
DOI10.1038/s42255-021-00440-5 PMID34531575 PMCIDPMC7611716 DivisionProtein & Nucleic Acid Chemistry -
Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma
AuthorsJacquelot N., Seillet C., Wang M., Pizzolla A., Liao Y., Hediyeh-Zadeh S., Grisaru-Tal S., Louis C., Huang Q., Schreuder J., Souza-Fonseca-Guimaraes F., de Graaf C. A., Thia K., Macdonald S., Camilleri M., Luong K., Zhang S., Chopin M., Molden-Hauer T., Nutt S. L., Umansky V., Ciric B., Groom J. R., Foster P. S., Hansbro P. M., McKenzie A. N. J., Gray D. H. D., Behren A., Cebon J., Vivier E., Wicks I. P., Trapani J. A., Munitz A., Davis M. J., Shi W., Neeson P. J., Belz G. T.
Journal
Nature Immunology
22(7):851-864. 7 June 2021 (2021)
Details
DOI10.1038/s41590-021-00943-z PMID34099918 PMCIDPMC7611091 DivisionProtein & Nucleic Acid Chemistry -
Mapping Rora expression in resting and activated CD4+ T cells
AuthorsHaim-Vilmovsky L., et al (including Walker J. A., Barlow J. L., McKenzie A. N. J.)
Journal
Plos one
16(5):e0251233. 18 May 2021 (2021)
Details
DOI10.1371/journal.pone.0251233 PMID34003838 PMCIDPMC8130942 DivisionProtein & Nucleic Acid Chemistry -
IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent
AuthorsHardman C. S., Chen Y. L., Salimi M., Nahler J., Corridoni D., Jagielowicz M., Fonseka C. L., Johnson D., Repapi E., Cousins D. J., Barlow J. L., McKenzie A. N. J., Simmons A., Ogg G.
Journal
Science Immunology
6(59):eabe5084. 14 May 2021 (2021)
Details
DOI10.1126/sciimmunol. Abe5084 PMID34021026 PMCIDPMC7611333 DivisionProtein & Nucleic Acid Chemistry -
Group 2 Innate Lymphoid Cells: Team Players in Regulating Asthma
AuthorsRodriguez-Rodriguez N., Gogoi M., McKenzie A. N. J.
Journal
Annual Review of Immunology
39:167-198. April 2021 (2021)
Details
DOI10.1146/annurev-immunol-110119‑091711 PMID33534604 PMCID DivisionProtein & Nucleic Acid Chemistry -
RORฮฑ is a critical checkpoint for T cell and ILC2 commitment in the embryonic thymus
AuthorsFerreira A. C. F., Szeto A. C. H., Heycock M. W. D., Clark P. A., Walker J. A., Crisp A., Barlow J. L., Kitching S., Lim A., Gogoi M., Berks R., Daly M., Jolin H. E., McKenzie A. N. J.
Journal
Nature Immunology
22(2):166-178. February 2021 (2021)
Details
DOI10.1038/s41590-020-00833‑w PMID33432227 PMCIDPMC7116838 DivisionProtein & Nucleic Acid Chemistry -
Type 2 Innate Lymphoid Cells Protect against Colorectal Cancer Progression and Predict Improved Patient Survival
AuthorsHuang Q., Jacquelot N., Preaudet A., Hediyeh-Zadeh S., Souza-Fonseca-Guimaraes F., McKenzie A. N. J., Hansbro P. M., Davis M. J., Mielke L. A., Putoczki T. L., Belz G. T.
Journal
Cancers
13(3):599. 1 February 2021 (2021)
Details
DOI10.3390/cancers13030559 PMID33535624 PMCIDPMC7867134 DivisionProtein & Nucleic Acid Chemistry -
Group-2 innate lymphoid cell-dependent regulation of tissue neutrophil migration by alternatively activated macrophage-secreted Ear11
AuthorsPanova V., Gogoi M., Rodriguez-Rodriguez N., Sivasubramaniam M., Jolin H. E., Heycock M. W. D., Walker J. A., Rana B. M. J., Drynan L. F., Hodskinson M., Pannell R., King G., Wing M., Easton A. J., Oedekoven C. A., Kent D. G., Fallon P. G., Barlow J. L., McKenzie A. N. J.
Journal
Mucosal Immunology
14(1):26-37. January 2021 (2021)
Details
DOI10.1038/s41385-020-0298‑2 PMID32457448 PMCIDPMC7790759 DivisionProtein & Nucleic Acid Chemistry -
Tumor-Infiltrating Regulatory T-cell Accumulation in the Tumor Microenvironment Is Mediated by IL33/ST2 Signaling
AuthorsSon J., Cho J. W., Park H. J., Moon J., Park S., Lee H., Lee J., Kim G., Park S. M., Lira S. A., Mckenzie A. N., Kim H. Y., Choi C. Y., Lim Y. T., Park S. Y., Kim H. R., Park S. H., Shin E. C., Lee I., Ha S. J.
Journal
Cancer Immunology Research
8(11):1393-1406. November 2020 (2020)
Details
DOI10.1158/2326-6066. Cir-19‑0828 PMID32878747 PMCID DivisionProtein & Nucleic Acid Chemistry -
Haploinsufficiency of multiple del(5q) genes induce B cell abnormalities in mice
AuthorsLiu T., Ahmed T., Krysiak K., Shirai C. L., Shao J., Nunley R., Bucala R., McKenzie A., Ndonwi M., Walter M. J.
Journal
Leukemia Research
96:106428. September 2020 (2020)
Details
DOI10.1016/j.leukres.2020.106428 PMID32739655 PMCIDPMC7768807 DivisionProtein & Nucleic Acid Chemistry -
ILC2-driven innate immune checkpoint mechanism antagonizes NK cell antimetastatic function in the lung
AuthorsSchuijs M. J., Png S., Richard A. C., Tsyben A., Hamm G., Stockis J., Garcia C., Pinaud S., Nicholls A., Ros X. R., Su J., Eldridge M. D., Riedel A., Serrao E. M., Rodewald H. R., Mack M., Shields J. D., Cohen E. S., McKenzie A. N. J., Goodwin R. J. A., Brindle K. M., Marioni J. C., Halim T. Y. F.
Journal
Nature Immunology
21(9):998-1009. September 2020 (2020)
Details
DOI10.1038/s41590-020-0745‑y PMID32747815 PMCIDPMC7116357 DivisionProtein & Nucleic Acid Chemistry -
Group 2 Innate Lymphoid Cells Promote Development of T Follicular Helper Cells and Initiate Allergic Sensitization to Peanuts
AuthorsKrempski J. W., Kobayashi T., Iijima K., McKenzie A. N., Kita H.
Journal
Journal of Immunology
204(12):3086-3096 (2020)
Details
DOI10.4049/jimmunol.2000029 PMID32366582 PMCIDPMC7309436 DivisionProtein & Nucleic Acid Chemistry -
ILC2 activation by keratinocyte-derived IL-25 drives IL-13 production at sites of allergic skin inflammation
AuthorsLeyva-Castillo J. M., Galand C., Mashiko S., Bissonnette R., McGurk A., Ziegler S. F., Dong C., McKenzie A. N. J., Sarfati M., Geha R. S.
Journal
Journal of Allergy and Clinical Immunology
145(6):1606-1614.e4. June 2020 (2020)
Details
DOI10.1016/j.jaci.2020.02.026 PMID32179159 PMCIDPMC7282942 DivisionProtein & Nucleic Acid Chemistry -
Interleukin-33 Signaling Controls the Development of Iron-Recycling Macrophages
AuthorsLu Y., Basatemur G., Scott I. C., Chiarugi D., Clement M., Harrison J., Jugdaohsingh R., Yu X., Newland S. A., Jolin H. E., Li X., Chen X., Szymanska M., Haraldsen G., Palmer G., Fallon P. G., Cohen E. S., McKenzie A. N. J., Mallat Z.
Journal
Immunity
52(5):782-793.e5. 19 May 2020 (2020)
Details
DOI10.1016/j.immuni.2020.03.006 PMID32272082 PMCIDPMC7237885 DivisionProtein & Nucleic Acid Chemistry -
OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer
AuthorsDamgaard R. B., Jolin H. E., Allison M. E. D., Davies S. E., Titheradge H. L., McKenzie A. N. J., Komander D.
Journal
Cell Death and Differentiation
27(5):1457-1474. May 2020 (2020)
Details
DOI10.1038/s41418-020-0532‑1 PMID32231246 PMCIDPMC7206033 DivisionProtein & Nucleic Acid Chemistry -
Re-evaluation of human BDCA-2+ DC during acute sterile skin inflammation
AuthorsChen Y. L., Gomes T., Hardman C. S., Vieira Braga F. A., Gutowska-Owsiak D., Salimi M., Gray N., Duncan D. A., Reynolds G., Johnson D.,Salio M., Cerundolo V., Barlow J. L., McKenzie A. N. J., Teichmann S. A.,Haniffa M., Ogg G.
Journal
Journal of Experimental Medicine
217(3):e20190811. 2 March 2020 (2020)
Details
DOI10.1084/jem.20190811 PMID31845972 PMCIDPMC7062525 DivisionProtein & Nucleic Acid Chemistry - Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL-1ฮฒ AuthorsSchwartz C., Moran T., Saunders S. P., Kaszlikowska A., Floudas A., Bom J, Nunez G., Iwakura Y., O'Neill L., Irvine A. D., McKenzie A. N. J., Ogg G., Walsh P. T., Demengeot J., Fallon P. G. Journal Allergy 74(10):1920-1933. October 2019 (2019)
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A stromal cell niche sustains ILC2-mediated type-2 conditioning in adipose tissue
AuthorsRana B. M. J., Jou E., Barlow J. L., Rodriguez-Rodriguez N., Walker J. A., Knox C., Jolin H. E., Hardman C. S., Sivasubramaniam M., Szeto A., Cohen E. S., Scott I. C., Sleeman M. A., Chidomere C. I., Cruz Migoni S., Caamano J., Jorgensen H. F., Carobbio S., Vidal-Puig A., McKenzie A. N. J.
Journal
Journal of Experimental Medicine
216(9):1999-2009. 2 September 2019 (2019)
Details
DOI10.1084/jem.20190689 PMID31248899 PMCIDPMC6719433 DivisionProtein & Nucleic Acid Chemistry -
Polychromic reporter mice reveal unappreciated innate lymphoid cell progenitor heterogeneity and elusive ILC3 progenitors in bone marrow
AuthorsWalker J. A., Clark P. A., Crisp A., Barlow J. L., Szeto A., Ferreira A. C. F., Rana B. M. J., Jolin H. E., Rodriguez-Rodriguez N., Sivasubramaniam M., Pannell R., Cruickshank J., Daly M., Haim-Vilmovsky L., Teichmann S. A., McKenzie A. N. J.
Journal
Immunity
51(1):104-118.e7. 22 May 2019 (2019)
Details
DOI10.1016/j.immuni.2019.05.002 PMID31128961 PMCIDPMC6642165 DivisionProtein & Nucleic Acid Chemistry -
Group 2 innate lymphoid cells are redundant in experimental renal ischemia-reperfusion injury
AuthorsCameron G. J. M., Cautivo K. M., Loering S., Jiang S. H., Deshpande A. V., Foster P. S., McKenzie A. N. J., Molofsky A. B., Hansbro P. M., Starkey M. R.
Journal
Frontiers in Immunology
2019; 10: 826. 16 April 2019 (2019)
Details
DOI10.3389/fimmu.2019.00826 PMID31057549 PMCIDPMC6477147 DivisionProtein & Nucleic Acid Chemistry -
BET bromodomain inhibitor iBET151 impedes human ILC2 activation and prevents experimental allergic lung inflammation
AuthorsKerscher B., Barlow J. L., Rana B. M., Jolin H. E., Gogoi M., Bartholomew M. A., Jhamb D., Pandey A., Tough D. F., van Oosterhout A. J. M., McKenzie A. N. J.
Journal
Frontiers in Immunology
10:678. 9 April 2019 (2019)
Details
DOI10.3389/fimmu.2019.00678 PMID31024538 PMCIDPMC6465521 DivisionProtein & Nucleic Acid Chemistry -
Pulmonary group 2 innate lymphoid cells: surprises and challenges
AuthorsStarkey M. R., McKenzie A. N., Belz G. T., Hansbro P. M.
Journal
Mucosal Immunology
12(2):299-311. March 2019 (2019)
Details
DOI10.1038/s41385-018-0130‑4 PMID30664706 PMCIDPMC6436699 DivisionProtein & Nucleic Acid Chemistry -
Innate Lymphoid Cells of the Lung
AuthorsBarlow J. L., McKenzie A. N. J.
Journal
Annual Review of Physiology
81:429-452. February 2019 (2019)
Details
DOI10.1146/annurev-physiol-020518‑114630 PMID30742786 PMCID DivisionProtein & Nucleic Acid Chemistry -
Roles for T/B lymphocytes and ILC2s in experimental chronic obstructive pulmonary disease
AuthorsDonovan C., Starkey M. R., Kim R. Y., Rana B. M. J., Barlow J. L., Jones B., Haw T. J., Mono Nair P., Budden K., Cameron G. J. M., Horvat J. C., Wark P. A., Foster P. S., McKenzie A. N. J., Hansbro P. M.
Journal
Journal of Leukocyte Biology
105(1):143-150. January 2019 (2019)
Details
DOI10.1002/JLB.3AB0518‑178R PMID30260499 PMCIDPMC6487813 DivisionProtein & Nucleic Acid Chemistry -
Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation
AuthorsPramanik J., Chen X., Kar G., Henriksson J., Gomes T., Park J. E., Natarajan K., Meyer K. B., Miao Z., McKenzie A. N. J., Mahata B. Teichmann S. A.
Journal
Genome Medicine
10(1):76. 24 October 2018 (2018)
Details
DOI10.1186/s13073-018-0589‑3 PMID30355343 PMCIDPMC6199730 DivisionProtein & Nucleic Acid Chemistry -
MicroRNA-155 Protects Group 2 Innate Lymphoid Cells From Apoptosis to Promote Type-2 Immunity
AuthorsKnolle M. D1., Chin S. B., Rana B. M. J., Englezakis A., Nakagawa R., Fallon P. G., Git A., McKenzie A. N. J.
Journal
Frontiers in Immunology
9:2232. 9 October 2018 (2018)
Details
DOI10.3389/fimmu.2018.02232 PMID30356668 PMCIDPMC6189280 DivisionProtein & Nucleic Acid Chemistry -
Concerted IL-25R and IL-4Rฮฑ signaling drive innate type 2 effector immunity for optimal helminth expulsion
AuthorsSmith K. A., Lรถser S., Varyani F., Harcus Y., McSorley H. J., McKenzie A. N., Maizels R. M.
Journal
ELife
7: e38269. 21 September 2018 (2018)
Details
DOI10.7554/eLife.38269 PMID30238872 PMCIDPMC6173579 DivisionProtein & Nucleic Acid Chemistry -
Lack of type 2 innate lymphoid cells promote a type I driven enhanced immune response in contact hypersensitivity
AuthorsRafei-Shamsabadi D. A., van de Poel S., Dorn B., Kunz S., Martin S. F., Klose C. S. N., Arnold S. J., Tanriver Y., Ebert K., Diefenbach A., Halim T. Y. F., McKenzie A. N. J., Jakob T.
Journal
Journal of Investigative Dermatology
138(9):1962-1972. September 2018 (2018)
Details
DOI10.1016/j.jid.2018.03.001 PMID29526762 PMCIDPMC6117454 DivisionProtein & Nucleic Acid Chemistry - Innate Lymphoid Cells: 10 Years On AuthorsVivier E., Artis D., Colonna M., Diefenbach A., Di Santo J. P., Eberl G., Koyasu S., Locksley R. M., McKenzie A. N. J., Mebius R. E., Powrie F., Spits H.. Journal Cell 174(5):1054-1066. 23 August 2018 (2018)
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Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells
AuthorsHalim T. YF., Rana B. M. J, Walker J. A., Kerscher B., Knolle M. D., Jolin H. E., Serrao E. M., Haim-Vilmovsky L., Teichmann S. A., Rodewald H. R., Botto M., Vyse T. J., Fallon P. G., Li Z., Withers D. R., McKenzie A. N. J.
Journal
Immunity
48(6):1195-1207.e6. 19 June 2018 (2018)
Details
DOI10.1016/j.immuni.2018.05.003 PMID29907525 PMCIDPMC6015114 DivisionProtein & Nucleic Acid Chemistry - TH2 cell development and function AuthorsWalker J. A., McKenzie A. N. J. Journal Nature Reviews. Immunology 18(2):121-133. February 2018 (2018)
- IFN-ฮณ increases susceptibility to influenza A infection through suppression of group II innate lymphoid cells AuthorsCalifano D., Furuya Y., Roberts S., Avram D., McKenzie A. N. J., Metzger D. W. Journal Mucosal Immunology 11(1):209-219. January 2018 (2018)
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CD1a presentation of endogenous antigens by group 2 innate lymphoid cells
AuthorsHardman C. S., Chen Y. L., Salimi M., Jarrett R., Johnson D., Jรคrvinen V. J., Owens R. J., Repapi E., Cousins D. J., Barlow J. L., McKenzie A. N. J., Ogg G.
Journal
Science Immunology
2(18). 22 December 2017 (2017)
Details
DOI10.1126/sciimmunol. Aan5918 PMID29273672 PMCIDPMC5826589 DivisionProtein & Nucleic Acid Chemistry -
Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion
AuthorsMinutti C. M., Drube S., Blair N., Schwartz C., McCrae J. C., McKenzie A. N., Kamradt T., Mokry M., Coffer P. J., Sibilia M., Sijts A. J., Fallon P. G., Maizels R. M., Zaiss D. M.
Journal
Immunity
47(4):710-722.e6. 17 October 2017 (2017)
Details
DOI10.1016/j.immuni.2017.09.013 PMID29045902 PMCIDPMC5654729 DivisionProtein & Nucleic Acid Chemistry -
Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis
AuthorsTrabanelli S., Chevalier M. F., Martinez-Usatorre A., Gomez-Cadena A., Salomรฉ B., Lecciso M., Salvestrini V., Verdeil G., Racle J., Papayannidis C., Morita H., Pizzitola I., Grandclรฉment C., Bohner P., Bruni E., Girotra M., Pallavi R., Falvo P., Leibundgut E. O., Baerlocher G. M., Carlo-Stella C., Taurino D., Santoro A., Spinelli O., Rambaldi A., Giarin E., Basso G., Tresoldi C., Ciceri F., Gfeller D., Akdis C. A, Mazzarella L., Minucci S., Pelicci P. G., Marcenaro E., McKenzie A. N. J., Vanhecke D., Coukos G., Mavilio D., Curti A., Derrรฉ L., Jandus C.
Journal
Nature Communications
8(1):593. 19 September 2017 (2017)
Details
DOI10.1038/s41467-017-00678‑2 PMID28928446 PMCIDPMC5605498 DivisionProtein & Nucleic Acid Chemistry -
ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control
AuthorsSchwartz C., Khan A. R., Floudas A., Saunders S. P., Hams E., Rodewald H. R., McKenzie A. N. J., Fallon P. G.
Journal
Journal of Experimental Medicine
214(9):2507-2521. 4 September 2017 (2017)
Details
DOI10.1084/jem.20170051 PMID28747424 PMCIDPMC5584124 DivisionProtein & Nucleic Acid Chemistry - Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells AuthorsRauber S., Luber M., Weber S., Maul L., Soare A., Wohlfahrt T., Lin N. Y., Dietel K., Bozec A., Herrmann M., Kaplan M. H., Weigmann B., Zaiss M. M., Fearon U., Veale D. J., Caรฑete J. D., Distler O., Rivellese F., Pitzalis C., Neurath M. F., McKenzie A. N. J., Wirtz S., Schett G., Distler J. H. W, Ramming A. Journal Nature Medicine 23(8):938-944. August 2017 (2017)
-
IL-17 Receptor A Maintains and Protects the Skin Barrier To Prevent Allergic Skin Inflammation
AuthorsFloudas A., Saunders S. P., Moran T., Schwartz C., Hams E., Fitzgerald D. C., Johnston J. A., Ogg G. S., McKenzie A. N., Walsh P. T., Fallon P. G.
Journal
Journal of Immunology
199(2):707-717. 15 July 2017 (2017)
Details
DOI10.4049/jimmunol.1602185 PMID28615416 PMCIDPMC5509014 DivisionProtein & Nucleic Acid Chemistry -
Type-2 innate lymphoid cells control the development of atherosclerosis in mice
AuthorsNewland S. A., Mohanta S., Clรฉment M., Taleb S., Walker J. A., Nus M., Sage A. P., Yin C., Hu D., Kitt L. L., Finigan A. J., Rodewald H. R., Binder C. J., McKenzie A. N. J., Habenicht A. J., Mallat Z.
Journal
Nature Communications
8:15781. 7 June 2017 (2017)
Details
DOI10.1038/ncomms15781 PMID28589929 PMCIDPMC5467269 DivisionProtein & Nucleic Acid Chemistry - Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease AuthorsBruce D. W., Stefanski H. E., Vincent B. G., Dant T. A., Reisdorf S., Bommiasamy H., Serody D. A., Wilson J. E., McKinnon K. P., Shlomchik W. D., Armistead P. M., Ting J. P. Y., Woosley J. T., Blazar B. R., Zaiss D. M. W., McKenzie A. N. J., Coghill J. M., Serody J. S. Journal Journal of Clinical Investigation 127(5):1813-1825. 1 May 2017 (2017)
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STAT3 Activation Impairs the Stability of Th9 Cells
AuthorsUlrich B. J., Verdan F. F., McKenzie A. N., Kaplan M. H., Olson M. R.
Journal
Journal of Immunology
198(6):2302-2309. 15 March 2017 (2017)
Details
DOI10.4049/jimmunol.1601624 PMID28137893 PMCIDPMC5340611 DivisionProtein & Nucleic Acid Chemistry -
First-Breath-Induced Type 2 Pathways Shape the Lung Immune Environment
AuthorsSaluzzo S., Gorki A. D., Rana B. M., Martins R., Scanlon S., Starkl P., Lakovits K., Hladik A., Korosec A., Sharif O., Warszawska J. M., Jolin H., Mesteri I., McKenzie A. N., Knapp S.
Journal
Cell Reports
18(8):1893-1905. 21 February 2017 (2017)
Details
DOI10.1016/j. Celrep.2017.01.071 PMID28228256 PMCIDPMC5329122 DivisionProtein & Nucleic Acid Chemistry -
Dysregulation of type 2 innate lymphoid cells and TH2 cells impairs pollutant-induced allergic airway responses
AuthorsDe Grove K. C., Provoost S., Hendriks R. W., McKenzie A. N., Seys L. J., Kumar S., Maes T., Brusselle G. G., Joos G. F.
Journal
Journal of Allergy and Clinical Immunology
139(1):246-257.e4. January 2017 (2017)
Details
DOI10.1016/j.jaci.2016.03.044 PMID27315767 PMCIDPMC5420012 DivisionProtein & Nucleic Acid Chemistry - Single-cell RNA-seq identifies a PD-1hi ILC progenitor and defines its development pathway AuthorsYu Y., Tsang J. C., Wang C., Clare S., Wang J., Chen X., Brandt C., Kane L., Campos L. S., Lu L., Belz G. T., McKenzie A. N., Teichmann S. A., Dougan G., Liu P. Journal Nature 539(7627):102-106. 3 November 2016 (2016)
- IL-4-producing ILC2s are required for the differentiation of TH2 cells following Heligmosomoides polygyrus infection AuthorsPelly V. S., Kannan Y., Coomes S. M., Entwistle L. J., Rรผckerl D., Seddon B., MacDonald A. S., McKenzie A., Wilson M. S. Journal Mucosal Immunology 9(6):1407-1417. November 2016 (2016)
-
IL-33 promotes food anaphylaxis in epicutaneously sensitized mice by targeting mast cells
AuthorsGaland C., Leyva-Castillo J. M., Yoon J., Han A., Lee M. S., McKenzie A. N., Stassen M., Oyoshi M. K., Finkelman F. D., Geha R. S.
Journal
Journal of Allergy and Clinical Immunology
138(5):1356-1366. November 2016 (2016)
Details
DOI10.1016/j.jaci.2016.03.056 PMID27372570 PMCIDPMC5099088 DivisionProtein & Nucleic Acid Chemistry -
IL-33 Precedes IL-5 in Regulating Eosinophil Commitment and Is Required for Eosinophil Homeostasis
AuthorsJohnston L. K., Hsu C. L., Krier-Burris R. A., Chhiba K. D., Chien K. B., McKenzie A., Berdnikovs S., Bryce P. J.
Journal
Journal of Immunology
197(9):3445-3453. 1 November 2016
(2016)
Details
DOI10.4049/jimmunol.1600611 PMID27683753 PMCIDPMC5101160 DivisionProtein & Nucleic Acid Chemistry -
TIM-3 is not essential for development of airway inflammation induced by house dust mite antigens
AuthorsHiraishi Y., Nambu A., Shibui A., Nakanishi W., Yamaguchi S., Morita H., Iikura M., McKenzie A. N., Matsumoto K., Sudo K., Yamasoba T., Nagase T., Nakae S.
Journal
Allergology International : Official Journal of the Japanese Society of Allergology
65(4):459-465. 4 October 2016 (2016)
Details
DOI10.1016/j. Alit.2016.04.008 PMID27209052 PMCIDPMC5074363 DivisionProtein & Nucleic Acid Chemistry -
Respiratory syncytial virus infection activates IL-13-producing group 2 innate lymphoid cells through thymic stromal lymphopoietin
AuthorsStier M. T., Bloodworth M. H., Toki S., Newcomb D. C., Goleniewska K.,
Boyd K. L., Quitalig M., Hotard A. L., Moore M. L., Hartert T. V., Zhou B.,
McKenzie A. N., Peebles R. S. Jr
Journal
Journal of Allergy and Clinical Immunology
138(3):814-824.e11 (2016)
Details
DOI10.1016/j.jaci.2016.01.050 PMID27156176 PMCIDPMC5014571 DivisionProtein & Nucleic Acid Chemistry -
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
AuthorsDamgaard R. B., Walker J. A., Marco-Casanova P., Morgan N. V., Titheradge H. L., Elliott P. R., McHale D., Maher E. R., McKenzie A. N., Komander D.
Journal
Cell
166(5):1215-1230.e20. 25 August 2016 (2016)
Details
DOI10.1016/j. Cell.2016.07.019 PMID27523608 PMCIDPMC5002269 DivisionProtein & Nucleic Acid Chemistry -
Erratum to: Single cell analysis of CD4+ T cell differentiation reveals three major cell states and progressive acceleration of proliferation
AuthorsProserpio V., Piccolo A., Haim-Vilmovsky L., Kar G., Lรถnnberg T., Svensson V., Pramanik J., Natarajan K. N., Zhai W., Zhang X., Donati G., Kayikci M., Kotar J., McKenzie A. N., Montandon R., James K. R., Fernandez-Ruiz D., Heath W. R., Haque A., Billker O., Woodhouse S., Cicuta P., Nicodemi M., Teichmann S. A.
Journal
Genome Biology
17(1):133. 22 June 2016 (2016)
Details
DOI10.1186/s13059-016-0998-9 PMID27333907 PMCIDPMC4918121 DivisionProtein & Nucleic Acid Chemistry -
Single-cell analysis of CD4+ T-cell differentiation reveals three major cell states and progressive acceleration of proliferation
AuthorsProserpio V., Piccolo A., Haim-Vilmovsky L., Kar G., Lรถnnberg T., Svensson V., Pramanik J., Natarajan K. N., Zhai W., Zhang X., Donati G., Kayikci M., Kotar J., McKenzie A. N., Montandon R., Billker O., Woodhouse S., Cicuta P., Nicodemi M., Teichmann S. A.
Journal
Genome Biology
17(1):103. 12 May 2016 (2016)
Details
DOI10.1186/s13059-016-0957-5 PMID27176874 PMCIDPMC4866375 DivisionProtein & Nucleic Acid Chemistry -
IL-25/IL-33-responsive TH2 cells characterize nasal polyps with a default TH17 signature in nasal mucosa
AuthorsLam E. P., Kariyawasam H. H., Rana B. M , Durham S. R , McKenzie A. N., Powell N. , Orban N., Lennartz-Walker M., Hopkins C., Ying S., Rimmer J., Lund V. J., Cousins D. J., Till S. J.
Journal
The Journal of Allergy and Clinical Immunology
137(5):1514-1524. May 2016 (2016)
Details
DOI10.1016/j.jaci.2015.10.019 PMID26684290 PMCIDPMC4852988 DivisionProtein & Nucleic Acid Chemistry -
Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase
AuthorsJarrett R., Salio M., Lloyd-Lavery A., Subramaniam S., Bourgeois E., Archer C., Cheung K. L., Hardman C., Chandler D., Salimi M., Gutowska-Owsiak D., Bernardino de la Serna J., Fallon P. G., Jolin H., Mckenzie A., Dziembowski A., Podobas E. I., Bal W., Johnson D., Moody D. B, Cerundolo V., Ogg G.
Journal
Science Translational Medicine
8(325):325ra18. 10 February 2016 (2016)
Details
DOI10.1126/scitranslmed. Aad6833 PMID26865566 PMCIDPMC4872823 DivisionProtein & Nucleic Acid Chemistry -
Spontaneous atopic dermatitis is mediated by innate immunity, with the secondary lung inflammation of the atopic march requiring adaptive immunity
AuthorsSaunders S. P., Moran T., Floudas A., Wurlod F., Kaszlikowska A., Salimi M, Quinn E. M., Oliphant C. J., Nรบรฑez G., McManus R., Hams E., Irvine A. D., McKenzie A. N., Ogg G. S., Fallon P. G.
Journal
The Journal of Allergy and Clinical Immunology
137(2):482-491. 1 February 2016 (2016)
Details
DOI10.1016/j.jaci.2015.06.045 PMID26299987 PMCIDPMC4735016 DivisionProtein & Nucleic Acid Chemistry -
The helminth T2 RNase ฯ1 promotes metabolic homeostasis in an IL-33 and group 2 innate lymphoid cell-dependent mechanism
AuthorsHams E., Bermingham R., Wurlod F. A., Hogan A. E., O'Shea D., Preston R. J., Rodewald H. R., McKenzie A. N., Fallon P. G.
Journal
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
30(2):824-835. 1 February 2016 (2016)
Details
DOI10.1096/fj.15‑277822 PMID26490658 PMCIDPMC4973506 DivisionProtein & Nucleic Acid Chemistry - Group 2 innate lymphoid cells license dendritic cells to potentiate memory TH2 cell responses AuthorsHalim T. Y., Hwang Y. Y., Scanlon S. T., Zaghouani H., Garbi N., Fallon P. G., McKenzie A. N. Journal Nature Immunology 17(1):57-64. 1 January 2016 (2016)
-
Group 2 Innate Lymphoid Cells Express Functional NKp30 Receptor Inducing Type 2 Cytokine Production
AuthorsSalimi M., Xue L., Jolin H., Hardman C., Cousins D. J., McKenzie A. N., Ogg G. S.
Journal
Journal of Immunology
196(1):45-54. 1 January 2016 (2016)
Details
DOI10.4049/jimmunol.1501102 PMID26582946 PMCIDPMC4913864 DivisionProtein & Nucleic Acid Chemistry - Inflammation-induced formation of fat-associated lymphoid clusters AuthorsBรฉnรฉzech C., Luu N. T., Walker J. A., Kruglov A. A., Loo Y., Nakamura K., Zhang Y., Nayar S., Jones L. H., Flores-Langarica A., McIntosh A., Marshall J., Barone F., Besra G., Miles K., Allen J. E., Gray M., Kollias G., Cunningham A. F., Withers D. R., Toellner K. M., Jones N. D., Veldhoen M., Nedospasov S. A., McKenzie A. N., Caamaรฑo J. H. Journal Nature Immunology 16(8):819-828. August 2015 (2015)
-
An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers
AuthorsMorita H., Arae K., Unno H., Miyauchi K., Toyama S., Nambu A., Oboki K., Ohno T., Motomura K., Matsuda A., Yamaguchi S., Narushima S., Kajiwara N., Iikura M., Suto H., McKenzie A. N., Takahashi T., Karasuyama H., Okumura K., Azuma M., Moro K., Akdis C. A., Galli S. J., Koyasu S., Kubo M., Sudo K., Saito H., Matsumoto K., Nakae S.
Journal
Immunity
43(1):175-186. 21 July 2015 (2015)
Details
DOI10.1016/j.immuni.2015.06.021 PMID26200013 PMCIDPMC4533925 DivisionProtein & Nucleic Acid Chemistry -
Bcl11b is essential for group 2 innate lymphoid cell development
AuthorsWalker J. A., Oliphant C. J., Englezakis A., Yu Y., Clare S., Rodewald H. R., Belz G., Liu P., Fallon P. G., McKenzie A. N.
Journal
The Journal of Experimental Medicine
212(6):875-882. 01 June 2015 (2015)
Details
DOI10.1084/jem.20142224 PMID25964370 PMCIDPMC4451131 DivisionProtein & Nucleic Acid Chemistry - Innate lymphoid cells. Innate lymphoid cells: a new paradigm in immunology AuthorsEberl G., Colonna M., Di Santo J. P., McKenzie A. N. Journal Science 348(6237):aaa6566. 22 May 2015 (2015)
- A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells AuthorsCook P. C., Owen H., Deaton A. M., Borger J. G., Brown S. L., Clouaire T., Jones G. R., Jones L. H., Lundie R. J., Marley A. K., Morrison V. L., Phythian-Adams A. T., Wachter E., Webb L. M., Sutherland T. E., Thomas G. D., Grainger J. R., Selfridge J., McKenzie A. N., Allen J. E., Fagerholm S. C., Maizels R. M., Ivens A. C., Bird A., MacDonald A. S. Journal Nature Communications 6:6920. 24 April 2015 (2015)
-
Deciphering the transcriptional switches of innate lymphoid cell programming: the right factors at the right time.
AuthorsLim A. W., McKenzie A. N.
Journal
Genes and Immunity
16(3):177-186. April/May 2015 (2015)
Details
DOI10.1038/gene.2014.83 PMID25611557 PMCIDPMC4409422 DivisionProtein & Nucleic Acid Chemistry -
IL-9 regulates intestinal barrier function in experimental T cell-mediated colitis
AuthorsGerlach K., McKenzie A. N., Neurath M. F., Weigmann B.
Journal
Tissue Barriers
3(1-2):e983777. 22 January 2015 (2015)
Details
DOI10.4161/21688370.2014.983777 PMID25838986 PMCIDPMC4372018 DivisionProtein & Nucleic Acid Chemistry - The messenger between worlds: the regulation of innate and adaptive type-2 immunity by innate lymphoid cells. AuthorsScanlon S. T., McKenzie A. N. Journal Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology 45(1):9-20, 9-20 January 2015 (2015)
- The IL-13/IL-4Rฮฑ axis is involved in tuberculosis-associated pathology AuthorsHeitmann L., Abad Dar M., Schreiber T., Erdmann H., Behrends J., Mckenzie A. N., Brombacher F., Ehlers S., Hรถlscher C. Journal Journal of Pathology 234(3):338-350. November 2014 (2014)
-
GRAF1a is a brain-specific protein that promotes lipid droplet clustering and growth, and is enriched at lipid droplet junctions
AuthorsLucken-Ardjomande Hรคsler S., Vallis Y., Jolin H. E., McKenzie A. N., McMahon H. T.
Journal
Journal of Cell Science
127(Pt 21):4602-4619. 1 November 2014 (2014)
Details
DOI10.1242/jcs.147694 PMID25189622 PMCIDPMC4215711 DivisionNeurobiology, Protein & Nucleic Acid Chemistry -
Aberrant production of IL-13 by T cells promotes exocrinopathy in Id3 knockout mice
AuthorsBelle I., Mahlios J., McKenzie A., Zhuang Y.
Journal
Cytokine
69(2):226-233. October 2014 (2014)
Details
DOI10.1016/j. Cyto.2014.06.009 PMID25010390 PMCIDPMC4127355 DivisionProtein & Nucleic Acid Chemistry -
Type-2 innate lymphoid cells in human allergic disease
AuthorsBarlow J. L., McKenzie A. N.
Journal
Current Opinion in Allergy and Clinical Immunology
14(5):397-403. October 2014 (2014)
Details
DOI10.1097/ACI.0000000000000090 PMID25115682 PMCIDPMC4154789 DivisionProtein & Nucleic Acid Chemistry -
Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation
AuthorsBeale J., Jayaraman A., Jackson D. J., Macintyre J. D., Edwards M. R., Walton R. P., Zhu J., Ching Y. M., Shamji B., Edwards M., Westwick J., Cousins D. J., Hwang Y. Y., McKenzie A., Johnston S. L., Bartlett N. W.
Journal
Science Translational Medicine
6(256):256ra134. 1 October 2014 (2014)
Details
DOI10.1126/scitranslmed.3009124 PMID25273095 PMCIDPMC4246061 DivisionProtein & Nucleic Acid Chemistry - Innate lymphoid cells in inflammation and immunity AuthorsMcKenzie A. N., Spits H., Eberl G. Journal Immunity 41(3):366-374. 18 September 2014 (2014)
-
Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy
AuthorsMcSorley H. J., Blair N. F., Smith K. A., McKenzie A. N., Maizels R. M.
Journal
Mucosal Immunology
7(5):1068-1078. September 2014 (2014)
Details
DOI10.1038/mi.2013.123 PMID24496315 PMCIDPMC4016792 DivisionProtein & Nucleic Acid Chemistry -
MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion
AuthorsOliphant C. J., Hwang Y. Y., Walker J. A., Salimi M., Wong S. H., Brewer J. M., Englezakis A., Barlow J. L., Hams E., Scanlon S. T., Ogg G. S., Fallon P. G., McKenzie A. N.
Journal
Immunity
41(2):283-295. 21 August 2014 (2014)
Details
DOI10.1016/j.immuni.2014.06.016 PMID25088770 PMCIDPMC4148706 DivisionProtein & Nucleic Acid Chemistry -
IL-33 and thymic stromal lymphopoietin mediate immune pathology in response to chronic airborne allergen exposure
AuthorsIijima K., Kobayashi T., Hara K., Kephart G. M., Ziegler S. F., McKenzie A. N., Kita H.
Journal
Journal of Immunology
93(4):1549-1559. 15 August 2014 (2014)
Details
DOI10.4049/jimmunol.1302984 PMID25015831 PMCIDPMC4119518 DivisionProtein & Nucleic Acid Chemistry -
The TNF-family cytokine TL1A promotes allergic immunopathology through group 2 innate lymphoid cells
AuthorsMeylan F., Hawley E. T., Barron L., Barlow J. L., Penumetcha P., Pelletier M., Sciumรจ G., Richard A. C., Hayes E. T., Gomez-Rodriguez J., Chen X., Paul W. E., Wynn T. A., McKenzie A. N., Siegel R. M.
Journal
Mucosal Immunology
7(4):958-968. July 2014 (2014)
Details
DOI10.1038/mi.2013.114 PMID24368564 PMCIDPMC4165592 DivisionProtein & Nucleic Acid Chemistry -
Single-cell RNA sequencing reveals T helper cells synthesizing steroids de novo to contribute to immune homeostasis
AuthorsMahata B., Zhang X., Kolodziejczyk A. A., Proserpio V., Haim-Vilmovsky L., Taylor A. E., Hebenstreit D., Dingler F. A., Moignard V., Gรถttgens B., Arlt W., McKenzie A. N., Teichmann S. A.
Journal
Cell Reports
7(4):1130-1142. 22 May 2014 (2014)
Details
DOI10.1016/j. Celrep.2014.04.011 PMID24813893 PMCIDPMC4039991 DivisionProtein & Nucleic Acid Chemistry -
Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells
AuthorsXue L,. Salimi M., Panse I., Mjรถsberg J. M., McKenzie A. N., Spits H., Klenerman P., Ogg G.
Journal
Journal of Allergy and Clinical Immunology
133(4):1184-1194. April 2014 (2014)
Details
DOI10.1016/j.jaci.2013.10.056 PMID24388011 PMCIDPMC3979107 DivisionProtein & Nucleic Acid Chemistry -
Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation
AuthorsHalim T. Y., Steer C. A., Mathรค L., Gold M. J., Martinez-Gonzalez I., McNagny K. M., McKenzie A. N., Takei F.
Journal
Immunity
40(3):425-435. 20 March 2014 (2014)
Details
DOI10.1016/j.immuni.2014.01.011 PMID24613091 PMCIDPMC4210641 DivisionProtein & Nucleic Acid Chemistry -
Chitin activates parallel immune modules that direct distinct inflammatory responses via innate lymphoid type 2 and ฮณฮด T cells
AuthorsVan Dyken S. J., Mohapatra A., Nussbaum J. C., Molofsky A. B., Thornton E. E., Ziegler S. F., McKenzie A. N., Krummel M. F., Liang H. E., Locksley R. M.
Journal
Immunity
40(3):414-424. 20 March 2014 (2014)
Details
DOI10.1016/j.immuni.2014.02.003 PMID24631157 PMCIDPMC4019510 DivisionProtein & Nucleic Acid Chemistry -
Vaginal Epithelial Cell-Derived S100 Alarmins Induced by Candida albicans via Pattern Recognition Receptor Interactions Are Sufficient but Not Necessary for the Acute Neutrophil Response during Experimental Vaginal Candidiasis
AuthorsYano J., Palmer G. E., Eberle K. E., Peters B. M., Vogl T., McKenzie A. N., Fidel P. L. Jr
Journal
Infection and Immunity
82(2):783-792. February 2014 (2014)
Details
DOI10.1128/IAI.00861‑13 PMID24478092 PMCIDPMC3911366 DivisionProtein & Nucleic Acid Chemistry -
IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis
AuthorsHams E., Armstrong M. E., Barlow J. L., Saunders S. P., Schwartz C., Cooke G. , Fahy R. J., Crotty T. B., Hirani N., Flynn R. J., Voehringer D., McKenzie A. N., Donnelly S. C., Fallon P. G.
Journal
Proceedings of the National Academy of Sciences, USA
111(1):367-372. 7 January 2014 (2014)
Details
DOI10.1073/pnas.1315854111 PMID24344271 PMCIDPMC3890791 DivisionProtein & Nucleic Acid Chemistry - TH9 cells that express the transcription factor PU.1 drive T cell-mediated colitis via IL-9 receptor signaling in intestinal epithelial cells AuthorsGerlach K., Hwang Y., Nikolaev A., Atreya R., Dornhoff H., Steiner S., Lehr H. A., Wirtz S., Vieth M., Waisman A., Rosenbauer F., McKenzie A. N., Weigmann B., Neurath M. F. Journal Nature Immunology 15(7):676-686. (2014)
- A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis AuthorsSalimi M., Barlow J. L., Saunders S. P., Xue L., Gutowska-Owsiak D., Wang X., Huang L. C., Johnson D., Scanlon S. T., McKenzie A. N., Fallon P. G., Ogg G. S. Journal Journal of Experimental Medicine 210(13):2939-2950. 9 December 2013 (2013)
- Cutting edge: IL-25 elicits innate lymphoid type 2 and type II NKT cells that regulate obesity in mice AuthorsHams E., Locksley R. M., McKenzie A. N., Fallon P. G. Journal Journal of Immunology 191(11):5349-5353. 1 December 2013 (2013)
- New kids on the block: group 2 innate lymphoid cells and type 2 inflammation in the lung AuthorsHalim T. Y., McKenzie A. N. Journal Chest 144(5):1681-1686. November 2013 (2013)
-
A Trypanosoma brucei kinesin heavy chain promotes parasite growth by triggering host arginase activity
AuthorsDe Muylder G., Daulouรจde S., Lecordier L., Uzureau P., Morias Y., Van Den Abbeele J., Caljon G., Hรฉrin M., Holzmuller P., Semballa S., Courtois P., Vanhamme L., Stijlemans B., De Baetselier P., Barrett M. P., Barlow J. L., McKenzie A. N., Barron L., Wynn T. A., Beschin A., Vincendeau P., Pays E.
Journal
PLoS Pathogens
9(10):e1003731. 31 October 2013 (2013)
Details
DOI10.1371/journal.ppat.1003731 PMID24204274 PMCIDPMC3814429 DivisionProtein & Nucleic Acid Chemistry - IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction AuthorsBarlow J. L., Peel S., Fox J., Panova V., Hardman C. S., Camelo A., Bucks C., Wu X., Kane C. M., Neill D. R., Flynn R. J., Sayers I., Hall I. P., McKenzie A. N. Journal Journal of Allergy and Clinical Immunology 132(4):933-941. October 2013 (2013)
-
The IL-33/ST2 axis is associated with human visceral leishmaniasis and suppresses Th1 responses in the livers of BALB/c mice infected with Leishmania donovani
AuthorsRostan O., Gangneux J. P., Piquet-Pellorce C., Manuel C., McKenzie A. N., Guiguen C., Samson M., Robert-Gangneux F.
Journal
MBio
4(5):e00383-13. 17 September 2013 (2013)
Details
DOI10.1128/mBio.00383‑13 PMID24045639 PMCIDPMC3774190 DivisionProtein & Nucleic Acid Chemistry - Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis AuthorsMcHedlidze T., W. Aldner M., Zopf S., Walker J., Rankin A. L., Schuchmann M., Voehringer D, McKenzie A. N., Neurath M. F., Pflanz S., Wirtz S. Journal Immunity 39(2):357-371. 22 August 2013 (2013)
- The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway AuthorsRankin L. C., Groom J. R., Chopin M., Herold M. J., Walker J. A., Mielke L. A., McKenzie A. N., Carotta S., Nutt S. L., Belz G. T. Journal Nature Immunology 14(4):389-395. April 2013 (2013)
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Development and function of group 2 innate lymphoid cells
AuthorsWalker J. A., McKenzie A. N.
Journal
Current Opinion in Immunology
25(2):148-155. April 2013 (2013)
Details
DOI10.1016/j. Coi.2013.02.010 PMID23562755 PMCIDPMC3776222 DivisionProtein & Nucleic Acid Chemistry - Innate lymphoid cells in immunity and disease AuthorsHwang Y. Y., McKenzie A. N. Journal Advances in Experimental Medicine and Biology 785:9-26. 11 February 2013 (2013)
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IL-33 citrine reporter mice reveal the temporal and spatial expression of IL-33 during allergic lung inflammation
AuthorsHardman C. S., Panova V., McKenzie A. N.
Journal
European Journal of Immunology
43(2):488-498. February 2013 (2013)
Details
DOI10.1002/eji.201242863 PMID23169007 PMCIDPMC3734634 DivisionProtein & Nucleic Acid Chemistry - Innate lymphoid cells--how did we miss them? AuthorsWalker J. A., Barlow J. L., McKenzie A. N. Journal Nature Reviews. Immunology 13(2):75-87. February 2013 (2013)
- Innate lymphoid cells - a proposal for uniform nomenclature AuthorsSpits H., Artis D., Colonna M., Diefenbach A., Di Santo J. P., Eberl G., Koyasu S., Locksley R. M., McKenzie A. N., Mebius R. E., Powrie F., Vivier E. Journal Nature Reviews. Immunology 13(2):145-149. February 2013 (2013)
- Direct control of hepatic glucose production by interleukin-13 in mice AuthorsStanya K. J., Jacobi D., Liu S., Bhargava P., Dai L., Gangl M. R., Inouye K., Barlow J. L., Ji Y., Mizgerd J. P., Qi L., Shi H., McKenzie A. N., Lee C. H. Journal Journal of Clinical Investigation 123(1):261-271. 2 January 2013 (2013)
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IL-25 drives remodelling in allergic airways disease induced by house dust mite
AuthorsGregory L. G., Jones C. P., Walker S. A., Sawant D., Gowers K. H., Campbell G. A., McKenzie A. N., Lloyd C. M.
Journal
Thorax
68(1):82-90. January 2013 (2013)
Details
DOI10.1136/thoraxjnl-2012‑202003 PMID23093652 PMCIDPMC3534261 DivisionProtein & Nucleic Acid Chemistry - Type 2 innate lymphoid cells: new players in asthma and allergy. AuthorsScanlon S. T., McKenzie A. N. Journal Current Opinion in Immunology 24(6):707-712. December 2012 (2012)
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Blocking IL-25 signalling protects against gut inflammation in a type-2 model of colitis by suppressing nuocyte and NKT derived IL‑13
AuthorsCamelo A., Barlow J. L., Drynan L. F., Neill D. R., Ballantyne S. J., Wong S. H., Pannell R., Gao W., Wrigley K., Sprenkle J., McKenzie A. N.
Journal
Journal of Gastroenterology
47(11):1198-1211. November 2012 (2012)
Details
DOI10.1007/s00535-012-0591‑2 PMID22539101 PMCIDPMC3501170 DivisionProtein & Nucleic Acid Chemistry -
Interleukin-33 amplifies IgE synthesis and triggers mast cell degranulation via interleukin-4 in naive mice
AuthorsKomai-Koma M., Brombacher F., Pushparaj P. N., Arendse B., McSharry C., Alexander J., Chaudhuri R., Thomson N. C., McKenzie A. N., McInnes I., Liew F. Y., Xu D.
Journal
Allergy
67(9):1118-1126. September 2012 (2012)
Details
DOI10.1111/j.1398-9995.2012.02859.x PMID22702477 PMCIDPMC3660789 DivisionProtein & Nucleic Acid Chemistry -
Full-length IL-33 promotes inflammation but not Th2 response in vivo in an ST2-independent fashion
AuthorsLuzina I. G., Pickering E. M., Kopach P., Kang P. H., Lockatell V., Todd N. W., Papadimitriou J. C., McKenzie A. N., Atamas S. P.
Journal
Journal of Immunology
189(1):403-410. 1 July 2012 (2012)
Details
DOI10.4049/jimmunol.1200259 PMID22634619 PMCIDPMC3381874 DivisionProtein & Nucleic Acid Chemistry - Innate lymphoid cells in the airways AuthorsWalker J. A., McKenzie A. Journal European Journal of Immunology 42(6):1368-1374. June 2012 (2012)
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The ST2 pathway is involved in acute pancreatitis: a translational study in humans and mice
AuthorsOuziel R., Gustot T., Moreno C., Arvanitakis M., Degrรฉ D., Trรฉpo E., Quertinmont E., Vercruysse V., Demetter P., Le Moine O., McKenzie A. N., Delhaye M., Deviรจre J., Lemmers A.
Journal
American Journal of Pathology
180(6):2330-2339. June 2012 (2012)
Details
DOI10.1016/j. Ajpath.2012.03.009 PMID22542450 PMCIDPMC3366073 DivisionProtein & Nucleic Acid Chemistry -
Epithelial cell-specific Act1 adaptor mediates interleukin-25-dependent helminth expulsion through expansion of Lin(-)c-Kit(+) innate cell population
AuthorsKang Z., Swaidani S., Yin W., Wang C., Barlow J. L., Gulen M. F., Bulek K., Do J. S., Aronica M., McKenzie A. N., Min B., Li X.
Journal
Immunity
36(5):821-833. 2012 (2012)
Details
DOI10.1016/j.immuni.2012.03.021 PMID22608496 PMCIDPMC3376903 DivisionProtein & Nucleic Acid Chemistry - Transcription factor RORฮฑ is critical for nuocyte development AuthorsWong S. H., Walker J. A., Jolin H. E., Drynan L. F., Hams E., Camelo A., Barlow J. L., Neill D. R., Panova V., Koch U., Radtke F., Hardman C. S., Hwang Y. Y., Fallon P. G., McKenzie A. N. Journal Nature Immunology 13(3):229-236. March 2012 (2012)
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IL-33-responsive lineage- CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs
AuthorsBartemes K. R., Iijima K., Kobayashi T., Kephart G. M., McKenzie A. N., Kita H.
Journal
Journal of Immunology
188(3):1503-1513. 1 February 2012 (2012)
Details
DOI10.4049/jimmunol.1102832 PMID22198948 PMCIDPMC3262877 DivisionProtein & Nucleic Acid Chemistry - Innate IL-13-producing nuocytes arise during allergic lung inflammation and contribute to airways hyperreactivity AuthorsBarlow J. L., Bellosi A., Hardman C. S., Drynan L. F., Wong S. H., Cruickshank J. P., McKenzie A. N. Journal Journal of Allergy and Clinical Immunology 129(1):191-198.e4. January 2012 (2012)
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Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity
AuthorsKim H. Y., Chang Y. J., Subramanian S., Lee H. H., Albacker L. A., Matangkasombut P., Savage P. B., McKenzie A. N., Smith D. E., Rottman J. B., DeKruyff R. H., Umetsu D. T.
Journal
Journal of Allergy and Clinical Immunology
129(1):216-227.e1-6. January 2012 (2012)
Details
DOI10.1016/j.jaci.2011.10.036 PMID22119406 PMCIDPMC3246069 DivisionProtein & Nucleic Acid Chemistry -
Insights into the initiation of type 2 immune responses
AuthorsOliphant C. J., Barlow J. L., McKenzie A. N.
Journal
Immunology
134(4):378-385. December 2011 (2011)
Details
DOI10.1111/j.1365-2567.2011.03499.x PMID22044021 PMCID DivisionProtein & Nucleic Acid Chemistry - Nuocytes: expanding the innate cell repertoire in type-2 immunity AuthorsBarlow J. L., McKenzie A. N. Journal Journal of Leukocyte Biology 90(5):867-874. November 2011 (2011)
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Reciprocal expression of IL-25 and IL-17A is important for allergic airways hyperreactivity
AuthorsBarlow J. L., Flynn R. J., Ballantyne S. J., McKenzie A. N.
Journal
Clinical and Experimental Allergy
41(10):1447-1455. October 2011 (2011)
Details
DOI10.1111/j.1365-2222.2011.03806.x PMID21722219 PMCID DivisionProtein & Nucleic Acid Chemistry -
Tim1 and Tim3 are not essential for experimental allergic asthma
AuthorsBarlow J. L., Wong S. H., Ballantyne S. J., Jolin H. E., McKenzie A. N.
Journal
Clinical and Experimental Allergy
41(7):1012-1021. July 2011 (2011)
Details
DOI10.1111/j.1365-2222.2011.03728.x PMID21470319 PMCIDPMC3132443 DivisionProtein & Nucleic Acid Chemistry -
Endogenous IL-13 plays a crucial role in liver granuloma maturation during Leishmania donovani infection, independent of IL-4Rฮฑ-responsive macrophages and neutrophils
AuthorsMcFarlane E., Carter K. C., McKenzie A. N., Kaye P. M., Brombacher F., Alexander J.
Journal
Journal of Infectious Diseases
204(1):36-43. 1 July 2011 (2011)
Details
DOI10.1093/infdis/jir080 PMID21628656 PMCIDPMC3105032 DivisionProtein & Nucleic Acid Chemistry -
ST2 deletion enhances innate and acquired immunity to murine mammary carcinoma
AuthorsJovanovic I., Radosavljevic G., Mitrovic M., Juranic V. L., McKenzie A. N., Arsenijevic N., Jonjic S., Lukic M. L.
Journal
European Journal of Immunology
41(7):1902-12. July 2011 (2011)
Details
DOI10.1002/eji.201141417 PMID21484786 PMCIDPMC3746127 DivisionProtein & Nucleic Acid Chemistry - Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome AuthorsFinch A. J., Hilcenko C., Basse N., Drynan L. F., Goyenechea B., Menne T. F., Gonzรกlez Fernรกndez A., Simpson P., D'Santos C. S., Arends M. J., Donadieu J., Bellannรฉ-Chantelot C., Costanzo M., Boone C., McKenzie A. N., Freund S. M., Warren A. J. Journal Genes & Development 25(9):917-29. May 2011 (2011)
- Nuocytes and beyond: new insights into helminth expulsion AuthorsNeill D. R., McKenzie A. N. Journal Trends in Parasitology 27(5):214-221. May 2011 (2011)
- Interleukin-33 is expressed in differentiated osteoblasts and blocks osteoclast formation from bone marrow precursor cells AuthorsSchulze J., Bickert T., Beil F. T., Zaiss M. M., Albers J., Wintges K., Streichert T., Klaetschke K., Keller J., Hissnauer T. N., Spiro A. S., Gessner A., Schett G., Amling M., McKenzie A. N., Horst A. K., Schinke T. Journal Journal of Bone and Mineral Research 26(4):704-717. April 2011 (2011)
- IL-33 activates B1 cells and exacerbates contact sensitivity AuthorsKomai-Koma M., Gilchrist D. S., McKenzie A. N., Goodyear C. S., Xu D., Liew F. Y. Journal Journal of Immunology 186(4):2584-2591. 15 February 2011 (2011)
-
IL-9 production by regulatory T cells recruits mast cells that are essential for regulatory T cell-induced immune suppression
AuthorsEller K., Wolf D., Huber J. M., Metz M,. Mayer G., McKenzie A. N., Maurer M., Rosenkranz A. R., Wolf A. M.
Journal
Journal of Immunology
186(1):83-91. 1 January 2011 (2011)
Details
DOI10.4049/jimmunol.1001183 PMID21115728 PMCIDPMC3227733 DivisionProtein & Nucleic Acid Chemistry - Advances in the 5q- syndrome AuthorsBoultwood J., Pellagatti A., McKenzie A. N., Wainscoat J. S. Journal Blood 116(26):5803-5811. 23 December 2010 (2010)
- New insights into 5q- syndrome as a ribosomopathy AuthorsBarlow J. L., Drynan L. F., Trim N. L., Erber W. N., Warren A. J., McKenzie A. N. Journal Cell Cycle 9(21):4286-4293. 1 November 2010 (2010)
-
Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in mice
AuthorsMiller A. M., Asquith D. L., Hueber A. J., Anderson L. A., Holmes W. M., McKenzie A. N., Xu D., Sattar N., McInnes I. B., Liew F. Y.
Journal
Circulation Research
107(5):650-658. 3 September 2010 (2010)
Details
DOI10.1161/CIRCRESAHA.110.218867 PMID20634488 PMCIDPMC4254700 DivisionProtein & Nucleic Acid Chemistry -
Tim-1 is induced on germinal centre B cells through B-cell receptor signalling but is not essential for the germinal centre response
AuthorsWong S. H., Barlow J. L., Nabarro S., Fallon P. G., McKenzie A. N.
Journal
Immunology
131(1):77-88. 1 September 2010 (2010)
Details
DOI10.1111/j.1365-2567.2010.03276.x PMID20518819 PMCID DivisionProtein & Nucleic Acid Chemistry - TH9: the latest addition to the expanding repertoire of IL-25 targets AuthorsNeill D. R., McKenzie A. N. Journal Immunology and Cell Biology 88(5):502-504. July 2010 (2010)
-
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
AuthorsNeill D. R., Wong S. H., Bellosi A., Flynn R. J., Daly M., Langford T. K., Bucks C., Kane C. M., Fallon P. G., Pannell R., Jolin H. E., McKenzie A. N.
Journal
Nature
464(7293):1367-1370. 29 April 2010 (2010)
Details
DOI10.1038/nature08900 PMID20200518 PMCIDPMC2862165 DivisionProtein & Nucleic Acid Chemistry - Induction of p53 and up-regulation of the p53 pathway in the human 5q- syndrome AuthorsPellagatti A., Marafioti T., Paterson J. C., Barlow J. L., Drynan L. F., Giagounidis A., Pileri S. A., Cazzola M., McKenzie A. N., Wainscoat J. S., Boultwood J. Journal Blood 115(13):2721-2723. 1 April 2010 (2010)
- C-type lectin SIGN-R1 has a role in experimental colitis and responsiveness to lipopolysaccharide AuthorsSaunders S. P., Barlow J. L., Walsh C. M., Bellsoi A., Smith P., McKenzie A. N., Fallon P. G. Journal Journal of Immunology 184(5):2627-2637. 1 March 2010 (2010)
- IL-33 exacerbates autoantibody-induced arthritis AuthorsXu D., Jiang H-R., Li Y., Pushparaj P. N., Kurowska-Stolarska M., Leung B. P., Mu R., Tay H. K., McKenzie A. N. J., McInnes I. B., Melendez A. J., Liew F. Y. Journal Journal of Immunology 184(5):2620-2626. 1 March 2010 (2010)
- IL-33 receptor (T1/ST2) signalling is necessary to prevent the development of encephalitis in mice infected with Toxoplasma gondii AuthorsJones L. A., Roberts F., Nickdel M. B., Brombacher F., McKenzie A. N., Henriquez F. L., Alexander J., Roberts C. W. Journal European Journal of Immunology 40(2):426-436. February 2010 (2010)
- A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome. AuthorsBarlow J. L., Drynan L. F., Hewett D. R., Holmes L. R., Lorenzo-Abalde S., Lane A. L., Jolin H. E., Pannell R., Middleton A. J., Wong S. H., Warren A. J., Wainscoat J. S., Boultwood J., McKenzie A. N. J. Journal Nature Medicine 16 (1): 59-66. January 2010 (2010)
-
A critical role of SHP-1 in regulation of type 2 inflammation in the lung
AuthorsSun Young Oh, Tao Zheng, Yoon-Keun Kim, Lauren Cohn, Robert J. Homer, Andrew N. J. McKenzie, Zhou Zhu
Journal
American Journal of Respiratory Cell and Molecular Biology
40(5):568-574. May 2009 (2009)
Details
DOI10.1165/rcmb.2008‑0225OC PMID18952567 PMCIDPMC2677436 DivisionProtein & Nucleic Acid Chemistry - IL-9 promotes IL-13-dependent paneth cell hyperplasia and up-regulation of innate immunity mediators in intestinal mucosa AuthorsValรฉrie Steenwinckel, Jamila Louahed, Muriel M. Lemaire, Caroline Sommereyns, Guy Warnier, Andrew McKenzie, Frank Brombacher, Jacques Van Snick, Jean-Christophe Renauld Journal Journal of Immunology 182(8):4737-4743. 15 April 2009 (2009)
- ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis AuthorsCatharina W. Wieland, Gerritje J. W. van der Windt, Sandrine Florquin, Andrew N. J. McKenzie, Tom van der Poll Journal Microbes and Infection 11(4):524-530. April 2009 (2009)
-
The C-type lectin SIGNR1 binds Schistosoma mansoni antigens in vitro, but SIGNR1-deficient mice have normal responses during schistosome infection
AuthorsSean P. Saunders, Caitriona M. Walsh, Jillian L. Barlow, Niamh E. Mangan, Philip R. Taylor, Andrew N. J. McKenzie, Philip Smith, Padraic G. Fallon
Journal
Infection and Immunity
77(1): 399-404 (2009) (2009)
Details
DOI10.1128/IAI.00762‑08 PMID18981244 PMCIDPMC2612259 DivisionProtein & Nucleic Acid Chemistry - IL-4/IL-13-dependent alternative activation of macrophages but not microglial cells is associated with uncontrolled cerebral cryptococcosis AuthorsWerner Stenzel, Uwe Mรผller, Gabriele Kรถhler, Frank L. Heppner, Manfred Blessing, Andrew N. J. McKenzie, Frank Brombacher, Gottfried Alber Journal American Journal of Pathology 174(2): 486-496 (2009) (2009)
- IL-25: a key requirement for the regulation of type-2 immunity AuthorsJillian L. Barlow, Andrew N. J. McKenzie Journal BioFactors 35(2):178-182 (2009) (2009)
- Pulmonary suppressor of cytokine signaling-1 induced by IL-13 regulates allergic asthma phenotype AuthorsSatoru Fukuyama, Takako Nakano, Takafumi Matsumoto, Brian G. G. Oliver, Janette K. Burgess, Atsushi Moriwaki, Kentaro Tanaka, Masato Kubo, Tomoaki Hoshino, Hiroyuki Tanaka, Andrew N. J. McKenzie, Koichiro Matsumoto, Hisamichi Aizawa, Yoichi Nakanishi, Akihiko Yoshimura, Judith L. Black, Hiromasa Inoue Journal American Journal of Respiratory and Critical Care Medicine 179(11):992-998 (2009) (2009)
- The cytokine interleukin-33 mediates anaphylactic shock AuthorsPeter N. Pushparaj, Hwee Kee Tay, Shiau Chen H'ng, Nick Pitman, Damo Xu, Andrew McKenzie, Foo Y. Liew, Alirio J. Melendez Journal Proceedings of the National Academy of Sciences, USA 106(24):9773-9778 (2009) (2009)
- IL-33 enhances lipopolysaccharide-induced inflammatory cytokine production from mouse macrophages by regulating lipopolysaccharide receptor complex AuthorsQuentin Espinassous, Elvira Garcia-de-Paco, Ignacio Garcia-Verdugo, Monique Synguelakis, Sonja von Aulock, Jean-Michel Sallenave, Andrew N. J. McKenzie, Jean Kanellopoulos Journal Journal of Immunology 183(2):1446-1455 (2009) (2009)
- Combined Th2 cytokine deficiency in donor T cells aggravates experimental acute graft-vs-host disease AuthorsIsao Tawara, Yoshinobu Maeda, Yaping Sun, Kathleen P. Lowler, Chen Liu, Tomomi Toubai, Andrew N. J. McKenzie, Pavan Reddy Journal Experimental Hematology 36 (8): 988-996 (2008)
- IL-33 exacerbates antigen-induced arthritis by activating mast cells AuthorsDamo Xu, Hui-Rong Jiang, Peter Kewin, Yubin Li, Rong Mu, Alasdair R. Fraser, Nick Pitman, Mariola Kurowska-Stolarska, Andrew N. J. McKenzie, Iain B. McInnes, Foo Y. Liew Journal Proceedings of the National Academy of Sciences of the United States of America 105 (31): 10913-10918 (2008)
- IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity AuthorsElizabeth E. Forbes, Katherine Groschwitz, J. Pablo Abonia, Eric B. Brandt, Elizabeth Cohen, Carine Blanchard, Richard Ahrens, Luqman Seidu, Andrew McKenzie, Richard Strait, Fred D. Finkelman, Paul S. Foster, Klaus I. Matthaei, Marc E. Rothenberg, Simon P. Hogan Journal Journal of Experimental Medicine 205 (4): 897-913 (2008)
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A novel mouse model of mycobacterium tuberculosis-induced granuloma necrosis: implications for adjuvant immunotherapy targeting TH2 cytokines in tuberculosis
AuthorsEhlers S., Schreiber T., Thye T., McKenzie A. N. J., Cutler A., Brombacher F., Horstmann R. D., Meyer C. G., Heitmann L., Holscher
Journal
Inflammation Research
57 (Suppl 2): S97-S97 (2008)
Details
DOI PMID PMCID Division -
Lineage commitment in mammary epithelium is regulated by type 2 cytokines and Stat6
AuthorsWT Khaled, SE Nicholson, FO Baxter, N Sprigg, JP Stingl, ANJ McKenzie, CJ Watson
Journal
Breast Cancer Research
10 (Suppl 2): S6 (2008)
Details
DOI PMID PMCID Division - IL-33 Induces Antigen-Specific IL-5+ T Cells and Promotes Allergic-Induced Airway Inflammation Independent of IL-4 AuthorsMariola Kurowska-Stolarska, Pete Kewin, Grace Murphy, Remo C. Russo, Bartosz Stolarski, Cristiana Couto Garcia, Mousa Komai-Koma, Nick Pitman, Yubin Li, Andrew N. J. McKenzie, Mauro M. Teixeira, Foo Y. Liew, Damo Xu Journal Journal of Immunology 181 (7): 4780-4790 (2008)
- Modulation of ozone-induced airway hyperresponsiveness and inflammation by interleukin‑13 AuthorsA. S. Williams, P. Nath, S-Y. Leung, N. Khorasani, A. N. J. McKenzie, I. M. Adcock, K. F. Chung Journal European Respiratory Journal 32 (3): 571-8 (2008)
- Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma AuthorsSarah J. Ballantyne, Jillian L. Barlow, Helen E. Jolin, Puneeta Nath, Alison S. Williams, Kian Fan Chung, Graham Sturton, See Heng Wong, Andrew N. J. McKenzie Journal J. Allergy Clin. Immunol. 120(6): 1324-1331 (2007) (2007)
- IL-13 induces disease-promoting type-2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformans AuthorsMueller U., Stenzel W., Kohler G., Werner C., Polte T., Hansen G., Schutze N., Straubinger R. K., Blessing M., McKenzie A. N. J., Brombacher F., Alber G. Journal Journal of Immunology 179(8): 5367-5377. 15 October 2007 (2007)
-
Complete inhibition of allergic airway inflammation and remodeling in quadruple IL-4/5/9/13-/- mice
AuthorsNath P., Leung S. Y., Williams A. S., Noble A., Xie S., McKenzie A. N. J.,Chung K. F.
Journal
Clin. Exp. Allergy
37(10): 1427-1435. October 2007 (2007)
Details
DOI10.1111/j.1365-2222.2007.02789.x PMID17883722 PMCID DivisionProtein & Nucleic Acid Chemistry - T1/ST2 expression on Th2 cells negatively regulates allergic pulmonary inflammation AuthorsMangan N. E., Dasvarma A., McKenzie A. N. J., Fallon P. G. Journal European Journal of Immunology 37(5): 1302-1312. May 2007 (2007)
-
The IL-4/IL-13/Stat6 signalling pathway promotes luminal mammary epithelial cell development
AuthorsWalid T. Khaled, Eliot K. C. Read, Sandra E. Nicholson, Fiona O. Baxter, Amelia J. Brennan, Paul J. Came, Naomi Sprigg, Andrew N. J. McKenzie, Christine J. Watson
Journal
Development
134(15): 2739-2750 (2007) (2007)
Details
DOI PMID PMCID Division -
IL-33 is a chemoattractant for human Th2 cells
AuthorsMousa Komai-Koma, Damo Xu, Yubin Li, Andrew N. J. McKenzie, Iain B. McInnes, Foo Y. Liew
Journal
European Journal of Immunology
37(10): 2779-2786 (2007) (2007)
Details
DOI PMID PMCID Division -
IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system
AuthorsShoji Sanada, Daihiko Hakuno, Luke J. Higgins, Eric R. Schreiter, Andrew N. J. McKenzie, Richard T. Lee
Journal
Journal of Clinical Investigation
117(6): 1538-1549 (2007) (2007)
Details
DOI PMID PMCID Division -
Infection with a helminth parasite prevents experimental colitis via a macrophage-mediated mechanism
AuthorsPhilip Smith, Niamh E. Mangan, Caitriona M. Walsh, Rosie E. Fallon, Andrew N. J. McKenzie, Nico van Rooijen, Padraic G. Fallon
Journal
Journal of Immunology
178(7): 4557-4566 (2007) (2007)
Details
DOI PMID PMCID Division -
IL-13 mediates in vivo IL-9 activities on lung epithelial cells but not on hematopoietic cells
AuthorsValerie Steenwinckel, Jamila Louahed, Ciriana Orabona, Francois Huaux, Guy Warnier, Andrew N. J. McKenzie, Dominique Lison, Roy Levitt, Jean-Christophe Renauld,
Journal
Journal of Immunology
178(5): 3244-3251 (2007) (2007)
Details
DOI PMID PMCID Division -
Mice lacking SIGNR1 have stronger T helper 1 responses to Mycobacterium tuberculosis
AuthorsCatharina W. Wieland, Estella A. Koppel, Jeroen den Dunnen, Sandrine Florquin, Andrew N. J. McKenzie, Yvette van Kooyk, Tom van der Poll, Teunis B. H. Geijtenbeek
Journal
Microbes & Infection
9(2): 134-141 (2007) (2007)
Details
DOI PMID PMCID Division -
Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion
AuthorsPadraic G. Fallon, Sarah J. Ballantyne, Niamh E. Mangan, Jillian L. Barlow, Ayan Dasvarma, Duncan R. Hewett, Ann McIlgorm, Helen E. Jolin, Andrew N. J. McKenzie
Journal
Journal of Experimental Medicine
203(4):1105-1116 (2006) (2006)
Details
DOI10.1084/jem.20051615 PMID16606668 PMCIDPMC2118283 DivisionProtein & Nucleic Acid Chemistry -
Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion
AuthorsPadraic G. Fallon, Sarah J. Ballantyne, Niamh E. Mangan, Jillian L. Barlow, Ayan Dasvarma , Duncan R. Hewett, Ann McIlgorm, Helen E. Jolin, Andrew N. J. McKenzie.
Journal
Journal of Experimental Medicine
203 : 1105-1116 (2006 )
Details
DOI PMID PMCID Division -
Helminth-modified pulmonary immune response protects mice from allergen-induced airway hyperresponsiveness
AuthorsNiamh E. Mangan, Nico van Rooijen, Andrew N. J. McKenzie, Padraic G. Fallon
Journal
Journal of Immunology
176 : 138-147 (2006) (2006)
Details
DOI PMID PMCID Division -
Periostin : a novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals
AuthorsGo Takayama, Kazuhiko Arima, Taisuke Kanaji, Shuji Toda, Hiroyuki Tanaka, Shunsuke Shoji, Andrew N. J. McKenzie, Hiroichi Nagai, Takao Hotokwbuchi, Kenji Izuhara
Journal
The Journal of Allergy and Clinical Immunology
118 : 98-104 (2006)
Details
DOI PMID PMCID Division -
Obligatory role for interleukin-13 in obstructive lesion development in airway allografts
AuthorsVibha N. Lama, Hiroaki Harada, Linda N. Badri, Andrew Flint, Cory M. Hogaboam, Andrew McKenzie, Fernando J. Martinez, Galen B. Toews, Bethany B. Moore, David J. Pinsky
Journal
American Journal of Pathology
169: 47-60 (2006) (2006)
Details
DOI PMID PMCID Division -
Periostin: a novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals
AuthorsGo Takayama, Kazuhiko Arima, Taisuke Kanaji, Shuji Toda, Hiroyuki Tanaka, Shunsuke Shoji, Andrew N. J. McKenzie, Hiroichi Nagai, Takao Hotokebuchi, Kenji Izuhara
Journal
J Allergy Clin Immunol
118: 98-104 (2006) (2006)
Details
DOI PMID PMCID Division - IL-13 regulates the immune response to inhaled antigens AuthorsPadilla J., Daley E., Chow A., Robinson K., Parthasarath K., McKenzie A. N. J., Tschernig T., Kurup V. P., Donaldson D. D., Grunig G. Journal Journal of Immunology 174(12):8097-8105. 15 June 2005 (2005)
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Lethal, neonatal ichthyosis with increased proteolytic processing of filaggrin in a mouse model of Netherton syndrome
AuthorsDuncan R. Hewett, Alison L. Simons, Niamh E. Mangan, Helen E. Jolin, Sheila M. Green, Padraic G. Fallon, Andrew N. J. McKenzie
Journal
Human Molecular Genetics
14 : 335-346 (2005) (2005)
Details
DOI PMID PMCID Division -
Development of allergic airway disease in mice following antibiotic therapy and fungal microbiota increase : role of host genetics, antigen and interleukin‑13
AuthorsMairi C. Noverr, Nicole R. Falkowski, Rod A. McDonald, Andrew N. McKenzie, Gary B. Huffnagle
Journal
Infection and Immunity
73 : 30-38 (2005) (2005)
Details
DOI PMID PMCID Division -
Interleukin-4 (IL-4) and IL-10 collude in vaccine failure for novel exacerbatory antigens in murine Leishmania major infection
AuthorsMark T. M. Roberts, Carmel B. Stober, Andrew N. McKenzie, Jenefer M. Blackwell
Journal
Infection and Immunity
73 : 7620-7628 (2005) (2005)
Details
DOI PMID PMCID Division -
Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity
AuthorsPhilip Smith, Rosie E. Fallon, Niamh E. Mangan, Caitriona M. Walsh, Margarida Saraiva, Jon R. Sayers, Andrew N. J. McKenzie, Antonio Alcami, Padraic G. Fallon
Journal
Journal of Experimental Medicine
202 : 1319-1325 (2005) (2005)
Details
DOI PMID PMCID Division -
ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance
AuthorsElizabeth K. Brint, Damo Xu, Haiying Liu, Aisling Dunne, Andrew N. J. McKenzie, Luke A. J. O'Neill, Foo Y. Liew
Journal
Nature Immunology
5: 373-379 (2004) (2004)
Details
DOI PMID PMCID Division -
Abolition of zolpidem sensitivity in mice with a point mutation in the GABA(A) receptor gamma2 subunit
AuthorsD. W. Cope, P. Wulff, A. Oberto, M. I. Aller, M. Capogna, F. Ferraguti, C. Halbsguth, H. Hoeger, H. E. Jolin, A. Jones, A. N. J. McKenzie, W. Ogris, A. Poeltl, S. T. Sinkkoen, O. Y. Vekovischeva, E. R. Korpi, W. Sieghart, E. Sigel, P. Somogyi, W. Wisden
Journal
Neuropharmacology
47: 17-34 (2004) (2004)
Details
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Protection from fluorescein isothiocyanate-induced fibrosis in IL-13-deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblasts
AuthorsJill E. Kolodsick, Galen B. Toews, Claudia Jakubzick, Cory Hogaboam, Thomas A. Moore, Andrew McKenzie, Carol A. Wilke, Cara J. Chrisman, Bethany B. Moore
Journal
Journal of Immunology
172: 4068-4076 (2004) (2004)
Details
DOI PMID PMCID Division -
SIGN-R1 contributes to protection against lethal pneumococcal infection in mice
AuthorsAstrid Lanoue, Menna R. Clatworthy, Philippa Smith, Sheila Green, Michael J. Townsend, Helen E. Jolin, Kenneth G. C. Smith, Padraic G. Fallon, Andrew N. J. McKenzie
Journal
J. Exp. Med.
200: 1383-1393 (2004) (2004)
Details
DOI PMID PMCID Division -
Lymphomagenesis, hydronephrosis, and autoantibodies result from dysregulation of IL-9 and are differentially dependent on Th2 cytokines
AuthorsAngus J. Lauder, Helen E. Jolin, Philippa Smith, Jose G. van den Berg, Alison Jones,
William Wisden, Kenneth G. C. Smith, Ayan Dasvarma, Padraic G. Fallon,
Andrew N. J. McKenzie
Journal
Journal of Immunology
173: 113-122 (2004) (2004)
Details
DOI PMID PMCID Division -
Regulation of Found in Inflammatory Zone 1 expression in bleomycin-induced lung fibrosis: role of IL-4/IL-13 and mediation via STAT-6
AuthorsTianju Liu, Hong Jin, Matthew Ullenbruch, Biao Hu, Naozumi Hashimoto, Bethany Moore, Andrew McKenzie, Nicholas W. Lukacs, Sem H. Phan
Journal
Journal of Immunology
173: 3425-3431 (2004) (2004)
Details
DOI PMID PMCID Division -
Helminth infection protects mice from anaphylaxis via IL-10-producing B cells
AuthorsNiamh E. Mangan, Rosemary E. Fallon, Philip Smith, Nico van Rooijen, Andrew N. McKenzie, Padraic G. Fallon
Journal
Journal of Immunology
173: 6346-6356 (2004) (2004)
Details
DOI PMID PMCID Division -
Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages
AuthorsPhilip Smith, Caitriona M. Walsh, Niamh E. Mangan, Rosie E. Fallon, Jon R. Sayers, Andrew N. J. McKenzie, Padraic G. Fallon
Journal
Journal of Immunology
173: 1240-1248 (2004) (2004)
Details
DOI PMID PMCID Division -
Accelerated prion disease in the absence of interleukin‑10
AuthorsAlana M. Thackray, Andrew N. McKenzie, Michael A. Klein, Angus Lauder, Raymond Bujdoso
Journal
Journal of Virology
78: 13697-13707 (2004) (2004)
Details
DOI PMID PMCID Division -
Immunological function in mice lacking the Rac-related GTPase RhoG
AuthorsElena Vigorito, Sarah Bell, Barbara J. Hebeis, Helen Reynolds, Simon McAdam, Piers C. Emson, Andrew McKenzie, Martin Turner
Journal
Molecular and Cellular Biology
24: 719-729 (2004) (2004)
Details
DOI PMID PMCID Division -
Polymorphisms in IL-4Ralpha correlate with airways hyperreactivity, eosinophilia, and Ym proteinexpression in allergic IL-13-/- mice
AuthorsDianne C. Webb, Klaus I. Matthaei, Yeping Cai, Andrew N. J. McKenzie, Paul S. Foster
Journal
Journal of Immunology
172: 1092-1098 (2004) (2004)
Details
DOI PMID PMCID Division -
Interleukin-13-dependent expression of matrix metalloproteinase-12 is required for the development of airway eosinophilia in mice
AuthorsMahmoud A. Pouladi, Clinton S. Robbins, Filip K. Swirski, Meghan Cundall, Andrew N. J. McKenzie, Manel Jordana, Steven D. Shapiro, Martin R. Stampfli
Journal
Am. J. Respir. Cell Mol. Biol.
30: 84-90 (2004) (2004)
Details
DOI PMID PMCID Division -
Cerebellar granule cell Cre recombinase expression
AuthorsM. I. Aller, A. Jones, D. Merlo, M. Paterlini, A. H. Meyer, U. Amtmann, S. Brickley, H. E. Jolin, A. N. J. McKenzie, H. Monyer, M. Farrant, W. Wisden
Journal
Genesis
36: 97-103 (2003) (2003)
Details
DOI PMID PMCID Division -
IL-13 is necessary, not simply sufficient, for epicutaneously induced Th2 responses to soluble protein antigen
AuthorsChristina A. Herrick, Lan Xu, Andrew N. J. McKenzie, Robert E. Tigelaar, Kim Bottomly
Journal
Journal of Immunology
170: 2488-2495 (2003) (2003)
Details
DOI PMID PMCID Division -
Decoy receptors in the regulation of T helper cell type 2 responses
AuthorsAndrew N. J. McKenzie, Padraic G. Fallon
Journal
J. Exp. Med.
197: 675-679 (2003) (2003)
Details
DOI PMID PMCID Division -
An essential role for IL-13 in maintaining a non-healing response following Leishmania mexicana infection
AuthorsJames Alexander, Frank Brombacher, H. Adrienne McGachy, Andrew N. J. McKenzie, William Walker, K. Christine Carter
Journal
Eur. J. Immunol.
32: 2923-2933 (2002) (2002)
Details
DOI PMID PMCID Division -
Th1 cells regulate hematopoietic progenitor cell homeostasis by production of Oncostatin M
AuthorsHal E. Broxmeyer, Heather A. Bruns, Shangming Zhang, Scott Cooper, Giao Hangoc, Andrew N. J. McKenzie, Alexander L. Dent, Ulrike Schindler, Lisa K. Naeger, Timothy Hoey, Mark H. Kaplan
Journal
Immunity
16: 815-825 (2002) (2002)
Details
DOI PMID PMCID Division -
Th2 activities induced during virgin T cell priming in the absence of IL-4, IL-13 and B cells
AuthorsAdam F. Cunningham, Padraic G. Fallon, Mahmood Khan, Sonia Vacheron, Hans Acha-Orbea, Ian C. M. MacLennan, Andrew N. McKenzie, Kai-Michael Toellner
Journal
Journal of Immunology
169: 2900-2906 (2002) (2002)
Details
DOI PMID PMCID Division -
IL-4 induces characteristic Th2 responses even in the combined absence of IL-5, IL-9, and IL‑13
AuthorsPadraic G. Fallon, Helen E. Jolin, Philippa Smith, Claire L. Emson, Michael J. Townsend, Rosie Fallon, Philip Smith, Andrew N. J. McKenzie
Journal
Immunity
17: 7-17 (2002) (2002)
Details
DOI PMID PMCID Division -
Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and Eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma
AuthorsJoerg Mattes, Ming Yang, Surendran Mahalingam, Joachim Kuehr, Dianne C. Webb, Ljubov Simson, Simon P. Hogan, Aulikki Koskinen, Andrew N. J. McKenzie, Lindsay A. Dent, Marc E. Rothenberg, Klaus I. Matthaei, Ian G. Young, Paul S. Foster
Journal
J. Exp. Med.
195: 1433-1444 (2002) (2002)
Details
DOI PMID PMCID Division -
The absence of interleukin 9 does not affect the development of allergen-induced pulmonary inflammation nor airway hyperreactivity
AuthorsSarah J. McMillan, Benjamin Bishop, Michael J. Townsend, Andrew N. McKenzie, Clare M. Lloyd
Journal
J. Exp. Med.
195: 51-57 (2002) (2002)
Details
DOI PMID PMCID Division -
Interleukin 18 (IL-18) in synergy with IL-2 induces lethal lung injury in mice: a potential role for cytokines, chemokines, and natural killer cells in the pathogenesis of interstitial pneumonia
AuthorsMasaki Okamoto, Seiya Kato, Kotaro Oizumi, Masaharu Kinoshita, Yoshimasa Inoue, Katsuaki Hoshino, Shizuo Akira, Andrew N. J. McKenzie, Howard A. Young, Tomoaki Hoshino
Journal
Blood
99: 1289-1298 (2002) (2002)
Details
DOI PMID PMCID Division -
Granulocyte macrophage colony-stimulating factor-driven respiratory mucosal sensitization induces Th2 differentiation and function independently of interleukin-4
AuthorsStacey A. Ritz, Meghan J. Cundall, Beata U. Gajewska, David Alvarez, Jose-Carlos Gutierrez-Ramos, Anthony J. Coyle, Andrew N. J. McKenzie, Martin R. Stampfli, Manel Jordana
Journal
Am. J. Respir. Cell Mol. Biol.
27: 428-435 (2002) (2002)
Details
DOI PMID PMCID Division -
Role of interleukin-13 in eosinophil accumulation and airway remodelling in a mouse model of chronic asthma
AuthorsR. K. Kumar, C. Herbert, M. Yang, A. M. L. Koskinen, A. N. J. McKenzie, P. S. Foster
Journal
Clin. Exp. Allergy
32: 1104-1111 (2002) (2002)
Details
DOI PMID PMCID Division -
IL-13 overexpression predisposes to anaphylaxis following antigen sensitization
AuthorsPadraic G. Fallon, Claire L. Emson, Philip Smith, Andrew N. J. McKenzie
Journal
Journal of Immunology
166: 2712-2717 (2001) (2001)
Details
DOI PMID PMCID Division -
Elemental signals regulating eosinophil accumulation in the lung
AuthorsPaul S. Foster, Arne W. Mould, Ming Yang, Jason Mackenzie, Joerg Mattes, Simon P. Hogan, Surendran Mahalingam, Andrew N. J. McKenzie, Marc E. Rothenberg, Ian G. Young, Klaus I. Matthaei, Dianne C. Webb
Journal
Immunological Reviews
179: 173-181 (2001) (2001)
Details
DOI PMID PMCID Division -
Failure to induce neonatal tolerance in mice that lack both IL-4 and IL-13 but not in those that lack IL-4 alone
AuthorsYoshihiko Inoue, Bogumila T. Konieczny, Maylene E. Wagener, Andrew N. J. McKenzie, Fadi G. Lakkis
Journal
Journal of Immunology
167: 1125-1128 (2001) (2001)
Details
DOI PMID PMCID Division -
IL-13 induces airways hyperreactivity independently of the IL-4Ralpha chain in the allergic lung
AuthorsJoerg Mattes, Ming Yang, Ana Siqueira, Kris Clark, Jason Mackenzie, Andrew N. J. McKenzie, Dianne C. Webb, Klaus I. Matthaei, Paul S. Foster
Journal
Journal of Immunology
167: 1683-1692 (2001) (2001)
Details
DOI PMID PMCID Division -
IL-13 gene-deficient mice are susceptible to cutaneous L. mexicana infection
AuthorsMariam Rodriguez Sosa, Lucia E. Rosas, Andrew N. J. McKenzie, Abhay R. Satoskar
Journal
Eur. J. Immunol.
31: 3255-3260 (2001) (2001)
Details
DOI PMID PMCID Division -
Critical role for IL-13 in the development of allergen-induced airway hyperreactivity
AuthorsDavid M. Walter, Jennifer J. McIntire, Gerald Berry, Andrew N. J. McKenzie, Debra D. Donaldson, Rosemarie H. DeKruyff, Dale T. Umetsu
Journal
Journal of Immunology
167: 4668-4675 (2001) (2001)
Details
DOI PMID PMCID Division -
Distinct spatial requirement for eosinophil-induced airways hyperreactivity
AuthorsD. C. Webb, A. N. J. McKenzie, K. I. Matthaei, M. E. Rothenberg, P. S. Foster
Journal
Immunology and Cell Biology
79: 165-169 (2001) (2001)
Details
DOI PMID PMCID Division -
Expression of the Ym2 lectin-binding protein is dependent on interleukin (IL)-4 and IL-13 signal transduction
AuthorsDianne C. Webb, Andrew N. J. McKenzie, Paul S. Foster
Journal
Journal of Biological Chemistry
276: 41969-41976 (2001) (2001)
Details
DOI PMID PMCID Division -
Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-alpha chain and STAT-6 independently of IL-5 and eotaxin
AuthorsMing Yang, Simon P. Hogan, Peter J. Henry, Klaus I. Matthaei, Andrew N. J. McKenzie, Ian G. Young, Marc E. Rothenberg, Paul S. Foster
Journal
Am. J. Respir. Cell Mol. Biol.
25: 522-530 (2001) (2001)
Details
DOI PMID PMCID Division -
T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses
AuthorsTownsend M. J., Fallon P. G., Matthews D. J., Jolin H. E., McKenzie A. N. J.
Journal
Journal of Experimental Medicine
191(6):1069-1076 (2000) (2000)
Details
DOI10.1084/jem.191.6.1069 PMID10727469 PMCIDPMC2193113 DivisionProtein & Nucleic Acid Chemistry - IL-13 is a susceptibility factor for Leishmania major infection AuthorsMatthews D. J., Emson C. L., McKenzie G. J., Jolin H. E., Blackwell J. M., McKenzie A. N. J. Journal Journal of Immunology 164(3):1458-1462 (2000) (2000)
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IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development
AuthorsMichael J. Townsend, Padraic G. Fallon, David J. Matthews, Philip Smith, Helen E. Jolin, Andrew N. J. McKenzie
Journal
Immunity
13: 573-583 (2000) (2000)
Details
DOI PMID PMCID Division -
Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agent
AuthorsPadraic G. Fallon, Emma J. Richardson, Grahame J. McKenzie, Andrew N. J. McKenzie
Journal
Journal of Immunology
164: 2585-2591 (2000) (2000)
Details
DOI PMID PMCID Division -
Integrated signals between IL-13, IL-4, and IL-5 regulate airways hyperreactivity
AuthorsDianne C. Webb, Andrew N. J. McKenzie, Aulikki M. L. Koskinen, Ming Yang, Joerg Mattes, Paul S. Foster
Journal
Journal of Immunology
165: 108-113 (2000) (2000)
Details
DOI PMID PMCID Division -
Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses
AuthorsMcKenzie G. J., Fallon P. G., Emson C. L., Grencis R. K., McKenzie A. N. J.
Journal
J. Exp. Med.
189(10):1565-1572. 17 May 1999 (1999)
Details
DOI10.1084/jem.189.10.1565 PMID10330435 PMCIDPMC2193635 DivisionProtein & Nucleic Acid Chemistry - Impaired development of Th2 cells in IL-13-deficient mice AuthorsMcKenzie G. J., Emson C. L., Bell S. E., Anderson S., Fallon P., Zurawski G., Murray R., Grencis R., McKenzie A. N. J. Journal Immunity 9(3):423-432. 1 September 1998 (1998)
- A critical role for IL-13 in resistance to intestinal nematode infection AuthorsBancroft A. J., McKenzie A. N. J., Grencis R. K. Journal Journal of Immunology 160(7):3453-3461. 1 April 1998 (1998)
- A distinct role for interleukin-13 in Th2-cell-mediated immune responses AuthorsMcKenzie G. J., Bancroft A., Grencis R. K., McKenzie A. N. J. Journal Current Biology 8(6):339-342. 12 March 1998 (1998)
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Interleukin (IL)-4-independent induction of immunoglobulin (Ig)E, and perturbationof T cell development in transgenic mice expressing IL‑13
AuthorsClaire L. Emson, Sarah E. Bell, Alison Jones, William Wisden, Andrew N. J. McKenzie
Journal
J. Exp. Med.
188: 399-404 (1998) (1998)
Details
DOI PMID PMCID Division -
An MII-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes
AuthorsJavier Corral, Isabelle Lavenir, Helen Impey, Alan J. Warren, Alan Forster, Teresa A. Larson, Sarah Bell, Andrew N. J. McKenzie, Gareth King, Terence H. Rabbitts
Journal
Cell
85: 853-861 (1996) (1996)
Details
DOI PMID PMCID Division