Published Research
Found 58 results for Leslie A.
- The CCP4 suite: integrative software for macromolecular crystallography AuthorsAgirre J, Atanasova M, Bagdonas H, Ballard CB, Baslé A, Beilsten-Edmands J, Borges RJ, Brown DG, Burgos-Mármol JJ, Berrisford JM, Bond PS, Caballero I, Catapano L, Chojnowski G, Cook AG, Cowtan KD, Croll TI, Debreczeni JÉ, Devenish NE, Dodson EJ, Drevon TR, Emsley P, Evans G, Evans PR, Fando M, Foadi J, Fuentes-Montero L, Garman EF, Gerstel M, Gildea RJ, Hatti K, Hekkelman ML, Heuser P, Hoh SW, Hough MA, Jenkins HT, Jiménez E, Joosten RP, Keegan RM, Keep N, Krissinel EB, Kolenko P, Kovalevskiy O, Lamzin VS, Lawson DM, Lebedev AA, Leslie AGW, Lohkamp B, Long F, Malý M, McCoy AJ, McNicholas SJ, Medina A, Millán C, Murray JW, Murshudov GN, Nicholls RA, Noble MEM, Oeffner R, Pannu NS, Parkhurst JM, Pearce N, Pereira J, Perrakis A, Powell HR, Read RJ, Rigden DJ, Rochira W, Sammito M, Sánchez Rodríguez F, Sheldrick GM, Shelley KL, Simkovic F, Simpkin AJ, Skubak P, Sobolev E, Steiner RA, Stevenson K, Tews I, Thomas JMH, Thorn A, Valls JT, Uski V, Usón I, Vagin A, Velankar S, Vollmar M, Walden H, Waterman D, Wilson KS, Winn MD, Winter G, Wojdyr M, Yamashita K. Journal Acta crystallographica. Section D, Structural Biology 79(Pt 6):449-461 (2023)
- The CCP4 suite: integrative software for macromolecular crystallography AuthorsAgirre J, Atanasova M, Bagdonas H, Ballard CB, Baslé A, Beilsten-Edmands J, Borges RJ, Brown DG, Burgos-Mármol JJ, Berrisford JM, Bond PS, Caballero I, Catapano L, Chojnowski G, Cook AG, Cowtan KD, Croll TI, Debreczeni JÉ, Devenish NE, Dodson EJ, Drevon TR, Emsley P, Evans G, Evans PR, Fando M, Foadi J, Fuentes-Montero L, Garman EF, Gerstel M, Gildea RJ, Hatti K, Hekkelman ML, Heuser P, Hoh SW, Hough MA, Jenkins HT, Jiménez E, Joosten RP, Keegan RM, Keep N, Krissinel EB, Kolenko P, Kovalevskiy O, Lamzin VS, Lawson DM, Lebedev AA, Leslie AGW, Lohkamp B, Long F, Malý M, McCoy AJ, McNicholas SJ, Medina A, Millán C, Murray JW, Murshudov GN, Nicholls RA, Noble MEM, Oeffner R, Pannu NS, Parkhurst JM, Pearce N, Pereira J, Perrakis A, Powell HR, Read RJ, Rigden DJ, Rochira W, Sammito M, Sánchez Rodríguez F, Sheldrick GM, Shelley KL, Simkovic F, Simpkin AJ, Skubak P, Sobolev E, Steiner RA, Stevenson K, Tews I, Thomas JMH, Thorn A, Valls JT, Uski V, Usón I, Vagin A, Velankar S, Vollmar M, Walden H, Waterman D, Wilson KS, Winn MD, Winter G, Wojdyr M, Yamashita K. Journal Acta crystallographica. Section D, Structural Biology 79(Pt 6):449-461 (2023)
- Molecular basis of β-arrestin coupling to formoterol-bound β1‑adrenoceptor AuthorsLee Y., Warne T., Nehmé R., Pandey S., Dwivedi-Agnihotri H., Chaturvedi M., Edwards P. C., García-Nafría J., Leslie A. G. W., Shukla A. K., Tate C. G. Journal Nature 583(7818):862-866. June 2020 (2020)
- Structure of F1-ATPase from the obligate anaerobe Fusobacterium nucleatum AuthorsPetri J., Nakatani Y., Montgomery M. G., Ferguson S. A., Aragão D., Leslie A. G. W., Heikal A., Walker J. E., Cook G. M. Journal Open Biology 9(6):190066. 5 June 2019 (2019)
- Molecular basis for high-affinity agonist binding in GPCRs AuthorsWarne T., Edwards P. C., Doré A. S., Leslie A. G. W., Tate C. G. Journal Science 364(6442):775-778. 24 May 2019 (2019)
- The structure of the catalytic domain of the ATP synthase from Mycobacterium smegmatis is a target for developing antitubercular drugs AuthorsZhang A. T., Montgomery M. G., Leslie A. G. W., Cook G. M., Walker J. E. Journal Proceedings of the National Academy of Sciences of the United States of America 116(10):4206-4211. 3 March 2019 (2019)
- ATP synthase from Trypanosoma brucei has an elaborated canonical F1-domain and conventional catalytic sites AuthorsMontgomery M. G., Gahura O., Leslie A. G. W., Zíková A., Walker J. E. Journal Proceedings of the National Academy of Sciences of the United States of America 115(9):2102-2107. 12 February 2018 (2018)
- Integrating macromolecular X-ray diffraction data with the graphical user interface iMosflm AuthorsPowell H. R., Battye T. G. G., Kontogiannis L., Johnson O., Leslie A. G. W. Journal Nature Protocols 12(7):1310-1325. July 2017 (2017)
- Regulation of the thermoalkaliphilic F1-ATPase from Caldalkalibacillus thermarum AuthorsFerguson S. A., Cook G. M., Montgomery M. G., Leslie A. G., Walker J. E. Journal Proceedings of the National Academy of Sciences of the United States of America 113(39):10860-10865. 27 September 2016 (2016)
- Structure of the adenosine A(2A) receptor bound to an engineered G protein AuthorsCarpenter B., Nehmé R., Warne T., Leslie A. G., Tate C. G. Journal Nature 536(7614):104-107. 4 August 2016 (2016)
- Pharmacological Analysis and Structure Determination of 7-Methylcyanopindolol-Bound β1-Adrenergic Receptor AuthorsSato T., Baker J., Warne T., Brown G., Leslie A., Congreve M., Tate C. Journal Molecular Pharmacology 88(6):1024-1034. December 2015 (2015)
- Ligand occupancy in crystal structure of β1-adrenergic G protein-coupled receptor AuthorsLeslie A. G., Warne T., Tate C. G. Journal Nature Structural & Molecular Biology 22(12):941-942. December 2015 (2015)
- Structure of ATP synthase from Paracoccus denitrificans determined by X-ray crystallography at 4.0 A resolution AuthorsMorales-Rios E., Montgomery M. G., Leslie A. G., Walker J. E. Journal Proceedings of the National Academy of Sciences of the United States of America 112(43):13231-13236. 27 October 2015 (2015)
- Structure of a catalytic dimer of the α- and β-subunits of the F-ATPase from Paracoccus denitrificans at 2.3 A resolution AuthorsMorales-Ríos E., Montgomery M. G., Leslie A. G., García-Trejo J. J., Walker J. E. Journal Acta Crystallographica. Section F, Structural Biology Communications 71(Pt 10):1309-1317. 1 October 2015 (2015)
- Structure of subcomplex Iβ of mammalian respiratory complex I leads to new supernumerary subunit assignments AuthorsZhu J., King M. S., Yu M., Klipcan L., Leslie A. G., Hirst J. Journal Proceedings of the National Academy of Sciences of the United States of America 112(39):12087-12092. 29 September 2015 (2015)
- MicroED data collection and processing AuthorsHattne J., Reyes F. E., Nannenga B. L., Shi D., de la Cruz M. J., Leslie A. G., Gonen T. Journal Acta Crystallographica. Section A, Foundations and Advances 71(Pt 4):353-360. July 2015 (2015)
- Molecular Determinants of CGS21680 Binding to the Human Adenosine A2A Receptor. AuthorsLebon G., Edwards P. C., Leslie A. G., Tate C. G. Journal Molecular Pharmacology 87(6):907-915. 01 June 2015 (2015)
- How release of phosphate from mammalian F1-ATPase generates a rotary substep AuthorsBason J. V., Montgomery M. G., Leslie A. G., Walker J. E. Journal Proceedings of the National Academy of Sciences of the United States of America 112(19):6009-6014. 12 May 2015 (2015)
- High-resolution structure determination by continuous-rotation data collection in MicroED AuthorsNannenga B. L., Shi D., Leslie A. G., Gonen T. Journal Nature Methods 11(9):927-930. September 2014 (2014)
- Pathway of binding of the intrinsically disordered mitochondrial inhibitor protein to F1‑ATPase AuthorsBason J. V., Montgomery M. G., Leslie A. G., Walker J. E. Journal Proceedings of the National Academy of Sciences, USA 111(31):11305-11310. 5 August 2014 (2014)
- The 2.1 A resolution structure of cyanopindolol-bound β1-adrenoceptor identifies an intramembrane Na+ ion that stabilises the ligand-free receptor AuthorsMiller-Gallacher J. L., Nehmé R., Warne T., Edwards P. C., Schertler G. F., Leslie A. G., Tate C. G. Journal PloS one 9(3):e92727. 24 March 2014 (2014)
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Structures of an apo and a binary complex of an evolved archeal B family DNA polymerase capable of synthesising highly cy-dye labelled DNA
AuthorsWynne S. A., Pinheiro V. B., Holliger P., Leslie A. G.
Journal
PloS one
8(8):e70892. 5 August 2013 (2013)
Details
DOI10.1371/journal.pone.0070892 PMID23940661 PMCIDPMC3733885 DivisionProtein & Nucleic Acid Chemistry, Structural Studies - Autoindexing diffraction images with iMosflm AuthorsPowell H. R., Johnson O., Leslie A. G. Journal Acta Crystallographica. Section D, Biological Crystallography 69(Pt 7):1195-1203. 1 July 2013 (2013)
- The structure of F₁-ATPase from Saccharomyces cerevisiae inhibited by its regulatory protein IF₁ AuthorsRobinson G. C., Bason J. V., Montgomery M. G., Fearnley I. M., Mueller D. M., Leslie A. G., Walker J. E. Journal Open Biology 3(2):120164. February 2013 (2013)
- Structural evidence of a new catalytic intermediate in the pathway of ATP hydrolysis by F1-ATPase from bovine heart mitochondria AuthorsRees D. M., Montgomery M. G., Leslie A. G., Walker J. E. Journal Proceedings of the National Academy of Sciences, USA 109(28):11139-11143. 10 July 2012 (2012)
- Crystal structures of a stabilized β1-adrenoceptor bound to the biased agonists bucindolol and carvedilol AuthorsWarne T., Edwards P. C., Leslie A. G., Tate C. G. Journal Structure 20(5):841-849. 9 May 2012 (2012)
- Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation AuthorsLebon G., Warne T., Edwards P. C., Bennett K., Langmead C. J,. Leslie A. G., Tate C. G. Journal Nature 474(7352):521-525. 18 May 2011 (2011)
- Two distinct conformations of helix 6 observed in antagonist-bound structures of a beta1-adrenergic receptor AuthorsMoukhametzianov R., Warne T., Edwards P. C., Serrano-Vega M. J., Leslie A. G., Tate C. G., Schertler G. F. Journal Proceedings of the National Academy of Sciences, USA 108(20):8228-8232. 17 May 2011 (2011)
- iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM AuthorsBattye T. G., Kontogiannis L., Johnson O., Powell H. R., Leslie A. G. Journal Acta Crystallographica. Section D, Biological Crystallography 67(4):271-281. 1 April 2011 (2011)
- Overview of the CCP4 suite and current developments AuthorsWinn M. D., Ballard C. C., Cowtan K. D., Dodson E. J., Emsley P., Evans P. R., Keegan R. M., Krissinel E. B., Leslie A. G., McCoy A., McNicholas S. J., Murshudov G. N., Pannu N. S., Potterton E. A., Powell H. R., Read R. J., Vagin A., Wilson K. S. Journal Acta Crystallographica. Section D 67(4):235-242. April 2011 (2011)
- The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor AuthorsWarne T., Moukhametzianov R., Baker J. G., Nehmé R., Edwards P. C., Leslie A. G., Schertler G. F., Tate C. G. Journal Nature 469(7329):241-244. 13 January 2011 (2011)
- Bioenergetic cost of making an adenosine triphosphate molecule in animal mitochondria AuthorsWatt I. N., Montgomery M. G., Runswick M. J., Leslie A. G., Walker J. E. Journal Proceedings of the National Academy of Sciences, USA 107(39):16823-16827. 28 September 2010 (2010)
- How the regulatory protein, IF(1), inhibits F(1)-ATPase from bovine mitochondria AuthorsGledhill J. R., Montgomery M. G., Leslie A. G. W., Walker J. E. Journal Proc Natl Acad Sci USA 104(40): 15671-15676 (2007) (2007)
- Mechanism of inhibition of bovine F1-ATPase by resveratrol and related polyphenols AuthorsGledhill J. R., Montgomery M. G., Leslie A. G. W., Walker J. E. Journal Proc Natl Acad Sci USA 104(34): 13632-13637 (2007) (2007)
- Ni-chelate-affinity purification and crystallization of the yeast mitochondrial F1‑ATPase AuthorsMueller D. M., Puri N., Kabaleeswaran V., Terry C., Leslie A. G. W.,Walker J. E. Journal Protein Expression & Purification 37(2):479-485. October 2004 (2004)
- Crystallization and preliminary crystallographic studies of the mitochondrial F1-ATPase from the yeast Saccharomyces cerevisiae AuthorsMueller D. M., Puri N., Kabaleeswaran V., Terry C., Leslie A. G. W., Walker J. E. Journal Acta Crystallographica Section D: Biological Crystallography 60(Pt 8):1441-1444. August 2004 (2004)
- The structure of bovine F1-ATPase inhibited by ADP and beryllium fluoride AuthorsKagawa R., Montgomery M. G., Braig K., Leslie A. G. W., Walker J. E. Journal EMBO Journal 23(14):2734-2744. 21 July 2004 (2004)
- Automation of the collection and processing of X-ray diffraction data - a generic approach AuthorsLeslie A. G. W., Powell H. R., Winter G., Svensson O., Spruce D.,McSweeney S., Love D., Kinder S., Duke E., Nave C. Journal Acta Crystallographica Section D: Biological Crystallography D58(Pt 11):1924-1928 (2002) (2002)
- Structure of bovine mitochondrial F1-ATPase with nucleotide bound to all three catalytic sites: implications for the mechanism of rotary catalyis AuthorsMenz R. I., Walker J. E., Leslie A. G. W. Journal Cell 106(3):331-341. 10 August 2001 (2001)
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The structure and nucleotide occupancy of bovine mitochondrial F1-ATPase are not influenced by crystallisation at high concentrations of nucleotide
AuthorsMenz R. I., Leslie A. G. W., Walker J. E.
Journal
FEBS Letters
494(1-2):11-14. 6 April 2001 (2001)
Details
DOI10.1016/s0014-5793(01)02302-x PMID11297725 PMCID DivisionProtein & Nucleic Acid Chemistry, Structural Studies - The rotary mechanism of ATP synthase AuthorsStock D., Gibbons C., Arechaga I., Leslie A. G. W., Walker J. E. Journal Current Opinion in Structural Biology 10(6):672-679. December 2000 (2000)
- How the multifunctional yeast Rap1p discriminates between DNA target sites: a crystallographic analysis AuthorsTaylor H. O. B., O'Reilly M., Leslie A. G. W., Rhodes D. Journal Journal of Molecular Biology 303(5):693-707. 10 November 2002 (2000)
- The structure of the central stalk in bovine F1-ATPase at 2.4 angstroms resolution AuthorsGibbons C., Montgomery M. G., Leslie A. G. W., Walker J. E. Journal Nature Structural Biology 7(11):1055-1061. November 2000 (2000)
- Structure of bovine mitochondrial F1-ATPase inhibited by Mg2+ADP and aluminium fluoride AuthorsBraig K., Menz R J., Montgomery M. G., Leslie A. G. W., Walker J. E. Journal Structure 8(6):567-573. June 2000 (2000)
- Structural model of F1-ATPase and the implications for rotary catalysis AuthorsLeslie A. G. W., Walker J. E. Journal Phil. Trans. R. Soc. Lond. B 355(1396):465-471. 29 April 2000 (2000)
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Molecular architecture of the rotary motor in ATP synthase
AuthorsStock D., Leslie A. G. W., Walker J. E.
Journal
Science
286(5445):1700-1705. 26 November 1999 (1999)
Details
DOI10.1126/science.286.5445.1700 PMID10576729 PMCID DivisionProtein & Nucleic Acid Chemistry - The crystal structure of the human hepatitis B virus capsid AuthorsWynne S. A., Crowther R. A., Leslie A. G. W. Journal Molecular Cell 3(6):771-780 (1999) (1999)
- The structure of bovine mitochondrial F-ATPase: an example of rotary catalysis AuthorsLeslie A. G. W., Abrahams J. P., Braig K., Lutter R., Menz R. I., Orriss G. L., van Raaij M. J., Walker J. E. Journal Biochemical Society Transactions 27(2):37-42. 1 February 1999 (1999)
- Crystallization of hepatitis B virus core protein shells: determination of cryoprotectant conditions and preliminary X-ray characterization AuthorsWynne S. A., Leslie A. G. W., Butler P. J. G., Crowther R. A. Journal Acta Crystallographica Section D D55: 557-560 (1999) (1999)
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Intergration of macromolecular diffraction data
AuthorsLeslie A. G. W.
Journal
Acta Crystallographica Section D
D55: 1696-1702 (1999) (1999)
Details
DOI PMID PMCID Division - The structure of bovine F1-ATPase complexed with the peptide antibiotic efrapeptin AuthorsAbrahams J. P., Buchanan S. K., van Raaij M. J., Fearnley I. M., Leslie A. G. W., Walker J. E. Journal Proceedings of the National Academy of Sciences, USA 93(18):9420-9424. September 1996 (1996)
- The structure of bovine F1-ATPase complexed with the antibiotic inhibitor aurovertin B Authorsvan Raaij M. J., Abrahams J. P., Leslie A. G. W., Walker J. E. Journal Proceedings of the National Academy of Sciences, USA 93(14):6913-6917. 9 July 1996 (1996)
- Methods used in the structure determination of bovine mitochondrial F1 ATPase AuthorsAbrahams J. P., Leslie A. G. W. Journal Acta crystallographica. Section D, Biological Crystallography 52(Pt 1):30-42. January 1996 (1996)
- Replacement of catalytic histidine-195 of chloramphenicol acetyltransferase: evidence for a general base role for glutamate AuthorsLewendon A., Murray I. A., Shaw W. V., Gibbs M. R., Leslie A. G. W. Journal Biochemistry 33(7):1944-1950. 22 February 1994 (1994)
- Chloramphenicol acetyltransferase AuthorsShaw W. V., Leslie A. G. W. Journal Annu. Rev. Biophys. Biophys. Chem 20: 363-86 (1991) (1991)
- Alternative binding modes for chloramphenicol and 1-substituted chloramphenicol analogues revealed by site-directed mutagenesis and x-ray crystallography of chloramphenicol acetyltransferase AuthorsMurray I. A., Lewendon A., Williams J. A., Cullis P. M., Shaw W. V., Leslie A. G. W. Journal Biochemistry 30(15):3763-3770 (1991) (1991)
- Crystal structure of ovalbumin as a model for the reactive centre of serpins AuthorsStein P. E., Leslie A. G. W., Finch J. T., Turnell W. G., McLaughlin P. J., Carrell R. W. Journal Nature 347(6288):99-102 (1990) (1990)
- Refined crystal structure of type III chloramphenicol acetyltransferase at 1.75 A resolution AuthorsLeslie A. G. W. Journal Journal of Molecular Biology 213(1):167-186. 5 May 1990 (1990)