Published Research
Found 61 results for Lancaster M.
- A human corticospinal organoid-slice connectoid model informs enhancer strategies for post-injury axon regrowth AuthorsGibbons G. M., Fuchsberger T., Abdelgawad M., Giandomenico S. L., Szebényi K., Petrova V., Wenger L. M. D., Olschewski D. N., Chabros J., Muresan L., Feord R. C., Asif M., Fawcett J. W., Mierau S. B., Paulsen O., Lancaster M. A., Lakatos A. Journal Cell Reports 45(6):117399 (2026)
- The prenatal sex steroid theory of autism after 25 years AuthorsBaron-Cohen S., Tsompanidis A., Srivastava D. P., Mill J., Lancaster M. A., Adhya D., APEX consortium, Warrier V. Journal Nature Human Behaviour 10(5):841-848 (2026)
- Modeling synaptic maturation from growth cone to synapse in human organoids AuthorsØhlenschlæger M. S., Criscuolo L., Jensen P., Lloyd-Davies Sánchez D. J., Sutcliffe M., Bhosale S., Bogetofte H., Tahir M., Jakobsen L. A., Pihl M., Brewer J., Schwämmle V., Poulsen F. R., Freude K., Lancaster M. A., Robinson P. J., Larsen M. R. Journal Journal of Neurochemistry 170(5):e70458 (2026)
- Diversity and complexity in neural organoids AuthorsChiaradia I., Lancaster M. A. Journal FEBS Letters (2026)
- Electrophysiological development and functional plasticity in dissociated human cerebral organoids across multiple cell lines AuthorsPavlinek A., Guerrisi S., O'Driscoll K., Polit L. D., Nagy R., APEX consortium, Lancaster M. A., Vernon A. C., Srivastava D. P. Journal Cell Reports Methods 6(4):101371 (2026)
- Protocol for quality control screening of brain organoid morphology AuthorsChiaradia I., Boulanger J., Elmkvist S. B., Larsen M. R., Lancaster M. A. Journal STAR Protocols 7(1):104423 (2026)
- How human-derived brain organoids are built differently from brain organoids derived from genetically-close relatives: a multi-scale hypothesis AuthorsZhang T., Gupta S., Lancaster M. A., Schwarz J. M. Journal Soft Matter 22(9):1979-1993 (2026)
- A cellular basis for the mammalian nocturnal-diurnal switch AuthorsBeale A. D., Christmas M. J., Rzechorzek N. M., Mihut A., Zeng A., Ellis C., James N. R., Smyllie N. J., Pilorz V., Richardson R., Bertelsen M. F., Fazal S. V., Voysey Z., Moreau K., Pelletier J., Crosby P., Peak-Chew S. Y., Edgar R. S., Lancaster M. A., Hut R. A., O'Neill J. S. Journal Science 391(6788):eady2822 (2026)
- Organizers in a dish: Modeling human CNS morphogenesis AuthorsMiller G., Lloyd-Davies Sánchez D. J., González Martínez J., Justin A. W., Lancaster M. A., Guglielmi L. Journal Developmental Cell 61(2):240-258 (2026)
- Multi-omic analysis of guided and unguided forebrain organoids reveals differences in cellular composition and metabolic profiles AuthorsØhlenschlæger M. S., Jensen P., Havelund J. F., Schmidt S. I., Mohamed F. A., Sutcliffe M., Elmkvist S. B., Criscuolo L., Wingett S. W., Chiaradia I., Bayram E., Nicolaisen J. A. A., Jakobsen L. A., Brewer J., Benros M. E., Freude K., Færgeman N. J., Lancaster M. A., Larsen M. R., Bogetofte H. Journal Cell Reports Methods 6(2):101295 (2026)
- A framework for neural organoids, assembloids and transplantation studies AuthorsPașca S. P., Arlotta P., Bateup H.S. , Camp J.G. , Cappello S. , Gage F.H. , Knoblich J.A. , Kriegstein A.R. , Lancaster M.A. , Ming G.L. , Novarino G. , Okano H. , Parmar M. , Park I.H., Reiner O. , Song H. , Studer L. , Takahashi J. , Temple S. , Testa G. , Treutlein B. , Vaccarino F.M. , Vanderhaeghen P. , Young-Pearse T. Journal Nature 639(8054):315-320 (2025)
- Inhibition of PRC2 enables self-renewal of blastoid-competent naive pluripotent stem cells from chimpanzee AuthorsHuang T., Radley A., Yanagida A., Ren Z., Carlisle F., Tahajjodi S., Kim D., O'Neill P., Clarke J., Lancaster M.A., Heckhausen Z., Zhuo J., Pedro Agostinho de Sousa J., Hajkova P., von Meyenn F., Imai H., Nakauchi H., Guo G., Smith A., Masaki H. Journal Cell Stem Cell 32(4):627-639.e8 (2025)
- Modelling human brain development and disease with organoids AuthorsBirtele M., Lancaster M., Quadrato G. Journal Nature reviews. Molecular Cell Biology (2024)
- MEA-NAP: A flexible network analysis pipeline for neuronal 2D and 3D organoid multielectrode recordings AuthorsSit T. P. H., Feord R. C., Dunn A. W. E., Chabros J., Oluigbo D., Smith H. H., Burn L., Chang E., Boschi A., Yuan Y., Gibbons G. M., Khayat-Khoei M., De Angelis F., Hemberg E., Hemberg M., Lancaster M. A., Lakatos A., Eglen S. J., Paulsen O., Mierau S. B. Journal Cell Reports Methods 4(11):100901 (2024)
- Unraveling mechanisms of human brain evolution AuthorsLancaster M. A. Journal Cell 187(21):5838-5857 (2024)
- Pluripotent stem cell-derived organoids: A brief history of curiosity-led discoveries AuthorsLancaster MA. Journal Bioessays Aug 5:e2400105. (2024)
- A molecular and cellular perspective on human brain evolution and tempo AuthorsLindhout FW, Krienen FM, Pollard KS, Lancaster MA. Journal Nature Jun;630(8017):596-608 (2024)
- Using organoids to model sex differences in the human brain. AuthorsPavlinek A, Adhya D, Tsompanidis A, Warrier V, APEX Consortium, Vernon AC, Lancaster M, Mill J, Srivastava DP, Baron-Cohen S Journal Biological psychiatry global open science 4(5):100343 (2024)
- A standardized nomenclature design for systematic referencing and identification of animal cellular material AuthorsSchrade L., Mah N., Bandrowski A., Chen Y., Dewender J., Diecke S., Hiepen C., Lancaster M. A., Marques-Bonet T., Martinez S., Mueller S. C., Navara C., Prigione A., Seltmann S., Sochacki J., Sutcliffe M. A., Zywitza V., Hildebrandt T. B., Kurtz A. Journal Animals : an Open Access Journal From MDPI 14(11):1541 (2024)
- Changing the public perception of human embryology AuthorsRivron NC, Martinez-Arias A, Sermon K, Mummery C, Schöler HR, Wells J, Nichols J, Hadjantonakis AK, Lancaster MA, Moris N, Fu J, Sturmey RG, Niakan K, Rossant J, Kato K. Journal Nature Cell Biology 25(12):1717-1719 (2023)
- Tissue morphology influences the temporal program of human brain organoid development AuthorsChiaradia I., Imaz-Rosshandler I., Nilges B. S., Boulanger J., Pellegrini L., Das R., Kashikar N. D., Lancaster M. A. Journal Cell Stem Cell 30(10):1351-1367.e10 (2023)
- ISSCR standards for the use of human stem cells in basic research AuthorsLudwig TE, Andrews PW, Barbaric I, Benvenisty N, Bhattacharyya A, Crook JM, Daheron LM, Draper JS, Healy LE, Huch M, Inamdar MS, Jensen KB, Kurtz A, Lancaster MA, Liberali P, Lutolf MP, Mummery CL, Pera MF, Sato Y, Shimasaki N, Smith AG, Song J, Spits C, Stacey G, Wells CA, Zhao T, Mosher JT. Journal Stem Cell Reports 18(9):1744-175 (2023)
- Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes AuthorsWarrier V, Stauffer EM, Huang QQ, Wigdor EM, Slob EAW, Seidlitz J, Ronan L, Valk SL, Mallard TT, Grotzinger AD, Romero-Garcia R, Baron-Cohen S, Geschwind DH, Lancaster MA, Murray GK, Gandal MJ, Alexander-Bloch A, Won H, Martin HC, Bullmore ET, Bethlehem RAI. Journal Nature Genetics 55(9):1483-1493 (2023)
- Progress and challenges in stem cell biology AuthorsApostolou E., Blau H., Chien K., Lancaster M. A., Tata P. R., Trompouki E., Watt F. M., Zeng Y. A., Zernicka-Goetz M. Journal Nature Cell Biology 25(2):203-206 (2023)
- Self-organizing brain organoids with ventricles amenable to injection and electroporation AuthorsLancaster M. A., Giandomenico S. L. Journal Gopalakrishnan, J. (ed.), Brain Organoid Research, Neuromethods. vol 189 pg 1- 16 (2023)
- CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder Authorsde Thonel A, Ahlskog JK, Daupin K, Dubreuil V, Berthelet J, Chaput C, Pires G, Leonetti C, Abane R, Barris LC, Leray I, Aalto AL, Naceri S, Cordonnier M, Benasolo C, Sanial M, Duchateau A, Vihervaara A, Puustinen MC, Miozzo F, Fergelot P, Lebigot É, Verloes A, Gressens P, Lacombe D, Gobbo J, Garrido C, Westerheide SD, David L, Petitjean M, Taboureau O, Rodrigues-Lima F, Passemard S, Sabéran-Djoneidi D, Nguyen L, Lancaster M, Sistonen L, Mezger V. Journal Nature Communications Nov 16;13(1):7002 (2022)
- Organoids as tools for fundamental discovery and translation-A Keystone Symposia report AuthorsCable J., Lutolf M.P., Park S.E., Apostolou A., Chen S., Song C.J., Spence J.R., Liberali P., Lancaster M., Meier A.B., Pek N.M.Q., Wells J.M., Capeling M.M., Uzquiano A., Musah S., Huch M., Gouti M., Hombrink P., Quadrato G., Urenda J.P. Journal Annals of the New York Academy of Sciences 1518(1):196-208 (2022)
- A nomenclature consensus for nervous system organoids and assembloids AuthorsPașca S.P., Arlotta P., Bateup H.S., Camp J.G., Cappello S., Gage F.H., Knoblich J.A., Kriegstein A.R., Lancaster M.A., Ming G.L., Muotri A.R., Park I.H., Reiner O., Song H., Studer L., Temple S., Testa G., Treutlein B., Vaccarino F.M. Journal Nature 609(7929):907-910 (2022)
- Androgens increase excitatory neurogenic potential in human brain organoids AuthorsKelava I., Chiaradia I., Pellegrini L., Kalinka A. T., Lancaster M. A. Journal Nature 602(7895):112-116 (2022)
- Breaking the barrier: In vitro models to study choroid plexus development AuthorsPellegrini L., Lancaster M. A. Journal Current Opinion in Cell Biology 73:41-49. December 2021 (2021)
- A protein-centric view of in vitro biological model systems for schizophrenia AuthorsChandrasekaran A., Jensen P., Mohamed F. A., Lancaster M., Benros M. E., Larsen M. R., Freude K. K. Journal Stem Cells 39(12):1569-1578 (2021)
- Electron cryo-tomography reveals the subcellular architecture of growing axons in human brain organoids AuthorsHoffmann P. C., Giandomenico S. L., Ganeva I., Wozny M. R., Sutcliffe M., Lancaster M. A., Kukulski W. Journal Elife 10:e70269 (2021)
- Modeling neurodegeneration with mutant-tau organoids AuthorsPellegrini L., Lancaster M. A. Journal Cell 184(17):4377-4379 (2021)
- An early cell shape transition drives evolutionary expansion of the human forebrain AuthorsBenito-Kwiecinski S., Giandomenico S. L., Sutcliffe M., Riis E. S., Freire-Pritchett P., Kelava I., Wunderlich S., Martin U., Wray G. A., McDole K., Lancaster M. A. Journal Cell 184(8):2084-2102.e19. 15 April 2021 (2021)
- Brain organoids: A new frontier of human neuroscience research AuthorsLancaster M. A. Journal Seminars in Cell & Developmental Biology 111:1-3. March 2021 (2021)
- Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation AuthorsJerber J., Seaton D. D., Cuomo A. S. E., Kumasaka N., Haldane J., Steer J., Patel M., Pearce D., Andersson M., Bonder M. J., Mountjoy E., Ghoussaini M., Lancaster M. A.; HipSci Consortium, Marioni J. C., Merkle F. T., Gaffney D. J., Stegle O. Journal Nature Genetics 53(3):304-312. March 2021 (2021)
- Voices of biotech research AuthorsAnnabi N., et al (including Lancaster M.) Journal Nature Biotechnology 39(3):281-286. March 2021 (2021)
- Rethinking organoid technology through bioengineering AuthorsGarreta E., Kamm R. D., Chuva de Sousa Lopes S. M., Lancaster M. A., Weiss R., Trepat X., Hyun I., Montserrat N. Journal Nature Materials 20(2):145-155. February 2021 (2021)
- Generation and long-term culture of advanced cerebral organoids for studying later stages of neural development AuthorsGiandomenico S. L., Sutcliffe M., Lancaster M. A. Journal Nature Protocols 16(2):579-602. February 2021 (2021)
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SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids
AuthorsPellegrini L., Albecka A., Mallery D. L., Kellner M. J., Paul D., Carter A. P., James L. C., Lancaster M. A.
Journal
Cell Stem Cell
27(6):951-961.e5. 3 December 2020 (2020)
Details
DOI10.1016/j.stem.2020.10.001 PMID33113348 PMCIDPMC7553118 DivisionStructural Studies, Protein & Nucleic Acid Chemistry, Cell Biology - Brain organoids for the study of human neurobiology at the interface of in vitro and in vivo AuthorsChiaradia I., Lancaster M. A. Journal Nature Neuroscience 23(12):1496-1508. December 2020 (2020)
- Brain Organoids: Human Neurodevelopment in a Dish AuthorsBenito-Kwiecinski S., Lancaster M. A. Journal Cold Spring Harbor Perspectives in Biology 12(8):a035709. 3 August 2020 (2020)
- Human CNS barrier-forming organoids with cerebrospinal fluid production AuthorsPellegrini L., Bonfio C., Chadwick J., Begum F., Skehel M., Lancaster M. A. Journal Science 369(6500). 10 July 2020 (2020)
- Voices in methods development AuthorsAnikeeva P., Boyden E., Brangwynne C., Cissé I. I., Fiehn O., Fromme P., Gingras A. C., Greene C. S., Heard E., Hell S. W., Hillman E., Jensen G. J., Karchin R., Kiessling L. L., Kleinstiver B. P., Knight R., Kukura P., Lancaster M. A., Loman N., Looger L., Lundberg E., Luo Q., Miyawaki A., Myers E. W. Jr., Nolan G. P., Picotti P., Reik W., Sauer M., Shalek A. K., Shendure J. , Slavov N., Tanay A., Troyanskaya O., van Valen D., Wang H. W., Yi C., Yin P., Zernicka-Goetz M., Zhuang X. Journal Nature Methods 16(10):945-951. October 2019 (2019)
- Disease modelling in human organoids AuthorsLancaster M. A., Huch M. Journal Disease Models & Mechanisms 12(7):dmm039347. 29 July 2019 (2019)
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Cerebral organoids at the air-liquid interface generate diverse nerve tracts with functional output
AuthorsGiandomenico S. L., Mierau S. B., Gibbons G. M., Wenger L. M. D., Masullo L., Sit T., Sutcliffe M., Boulanger J., Tripodi M., Derivery E., Paulsen O., Lakatos A., Lancaster M. A.
Journal
Nature Neuroscience
22(4):669-679. April 2019 (2019)
Details
DOI10.1038/s41593-019-0350‑2 PMID30886407 PMCIDPMC6436729 DivisionCell Biology, Neurobiology - An Electric Take on Neural Fate and Cortical Development AuthorsLancaster M. A. Journal Developmental Cell 48(1):1-2. 7 January 2019 (2019)
- Exploring landscapes of brain morphogenesis with organoids AuthorsJabaudon D., Lancaster M. Journal Development 145(22). 19 November 2018 (2018)
- Comprehensive comparative analysis of 5'-end RNA-sequencing methods AuthorsAdiconis X., Haber A. L., Simmons S. K., Levy Moonshine A., Ji Z., Busby M. A., Shi X., Jacques J., Lancaster M. A., Pan J. Q., Regev A., Levin J. Z. Journal Nature Methods 15(7):505-511. July 2018 (2018)
- Crinkle-cut brain organoids AuthorsLancaster M. A. Journal Cell Stem Cell 22(5):616-618. 1 May 2018 (2018)
- Brain organoids get vascularized AuthorsLancaster M. A. Journal Nature Biotechnology 36(5):407-408. 1 May 2018 (2018)
- Understanding the role of steroids in typical and atypical brain development: advantages of using a "brain in a dish" approach AuthorsAdhya D., Annuario E., Lancaster M. A., Price J., Baron-Cohen S., Srivastava D. P. Journal Journal of Neuroendocrinology 30(2). 1 February 2018 (2018)
- Guided self-organization and cortical plate formation in human brain organoids AuthorsLancaster M. A., Corsini N. S., Wolfinger S., Gustafson E. H., Phillips A. W., Burkard T. R., Otani T., Livesey F. J., Knoblich J. A. Journal Nature Biotechnology 35(7):659-666. July 2017 (2017)
- Non-model model organisms AuthorsRussell J. J., Theriot J. A., Sood P., Marshall W. F., Landweber L. F., Fritz-Laylin L., Polka J. K., Oliferenko S., Gerbich T., Gladfelter A., Umen J., Bezanilla M., Lancaster M. A., He S., Gibson M. C., Goldstein B., Tanaka E. M., Hu C. K., Brunet A. Journal BMC Biology 15(1):55. 29 June 2017 (2017)
- Self-organized developmental patterning and differentiation in cerebral organoids AuthorsRenner M., Lancaster M. A., Bian S., Choi H., Ku T., Peer A., Chung K., Knoblich J. A. Journal EMBO Journal 36(10):1316-1329. 15 May 2017 (2017)
- A Simple Method of Generating 3D Brain Organoids Using Standard Laboratory Equipment AuthorsSutcliffe M., Lancaster M. A. Journal Methods in Molecular Biology 31 March 2017 (2017)
- Probing human brain evolution and development in organoids AuthorsGiandomenico S. L., Lancaster M. A. Journal Current Opinion in Cell Biology 44:36-43. February 2017 (2017)
- Dishing out mini-brains: Current progress and future prospects in brain organoid research AuthorsKelava I., Lancaster M. A. Journal Developmental Biology 420(2):199-209. 15 December 2016 (2016)
- Stem Cell Models of Human Brain Development AuthorsKelava I., Lancaster M. A. Journal Cell Stem Cell 18(6):736-748. 2 June 2016 (2016)
- Human cerebral organoids recapitulate gene expression programs of fetal neocortex development AuthorsCamp J. G., Badsha F., Florio M., Kanton S., Gerber T., Wilsch-Bräuninger M., Lewitus E., Sykes A., Hevers W., Lancaster M., Knoblich J. A., Lachmann R., Pääbo S., Huttner W. B., Treutlein B. Journal Proceedings of the National Academy of Sciences of the United States of America 112(51):15672-15677. 22 December 2015 (2015)
- Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders AuthorsBrennand K. J., Marchetto M. C., Benvenisty N., Brüstle O., Ebert A., Izpisua Belmonte J. C , Kaykas A. , Lancaster M. A., Livesey F. J , McConnell M. J , McKay R. D , Morrow E. M., Muotri A. R , Panchision D. M., Rubin L. L., Sawa A., Soldner F., Song H., Studer L , Temple S., Vaccarino F. M., Wu J., Vanderhaeghen P., Gage F. H., Jaenisch R. Journal Stem Cell Reports 5(6):933-945. 8 December 2015 (2015)