Published Research

Found 11 results for Kozik.

• Anchoring of perforin-2 via the transmembrane domain is required for antigen escape into the cytosol AuthorsLaub M., Chatterjee R., Kozik P. Journal The EMBO Journal 45(19):6759-6781 (2026)
  Details

  DOI10.1038/s44318-026-00903-z PMID42618800 PMCIDPMC13631362 DivisionProtein & Nucleic Acid Chemistry
• TRIM21 induces selective autophagy of viruses and bacteria AuthorsRhinesmith T., Albecka A., Vaysburd M., Puri C., Luptak J., Boulanger J., Nguyen Le Q. M., Gratian M. J., O'Connell K., Few L., Donaldson-Wing M., Kozik P., Rubinsztein D. C., James L. C. Journal Molecular Cell 86(12):2410-2424.e10 (2026)
  Details

  DOI10.1016/j.molcel.2026.04.031 PMID42242206 PMCID  DivisionProtein & Nucleic Acid Chemistry
• Mef2d potentiates type-2 immune responses and allergic lung inflammation AuthorsSzeto ACH, Clark PA, Ferreira ACF, Heycock M, Griffiths EL, Jou E, Mannion J, Luan SL, Storrar S, Knolle MD, Kozik P, Jolin HE, Fallon PG, McKenzie ANJ. Journal Science 28;384(6703):eadl0370 (2024)
  Details

  DOI10.1126/science. Adl0370 PMID38935708 PMCIDPMC7616247 DivisionProtein & Nucleic Acid Chemistry
• Perforin-2 is a pore-forming effector of endocytic escape in cross-presenting dendritic cells AuthorsRodríguez-Silvestre P., Laub M., Krawczyk P. A, Davies A. K., Schessner J. P., Parveen R., Tuck B. J., McEwan W. A., Borner G. H. H, Kozik P. Journal Science 380(6651):1258-1265 (2023)
  Details

  DOIdoi.org/10.1126/science. Adg8802 PMID37347855 PMCIDPMC7614779 DivisionProtein & Nucleic Acid Chemistry
• Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation AuthorsFerreira A. C. F., Szeto A. C. H., Clark P. A., Crisp A., Kozik P., Jolin H. E., McKenzie A. N. J. Journal Immunity 56(7):1468-1484.e7 (2023)
  Details

  DOIdoi.org/10.1016/j.immuni.2023.05.010 PMID37285842 PMCIDPMC10501989 DivisionProtein & Nucleic Acid Chemistry
• An αvβ3 integrin checkpoint is critical for efficient T(H)2 cell cytokine polarization and potentiation of antigen-specific immunity AuthorsSzeto A.C.H., Ferreira A.C.F., Mannion J., Clark P.A., Sivasubramaniam M., Heycock M.W.D., Crisp A., Jolin H.E., Kozik P., Knolle M.D., McKenzie A.N.J. Journal Nature Immunology 24(1):123-135 (2022)
  Details

  DOI10.1038/s41590-022-01378‑w PMID36550322 PMCIDPMC7614022 DivisionProtein & Nucleic Acid Chemistry
• Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross‑presentation AuthorsGros M, Segura E, Rookhuizen DC, Baudon B, Heurtebise-Chrétien S, Burgdorf N, Maurin M, Kapp EA, Simpson RJ, Kozik P, Villadangos JA, Bertrand MJM, Burbage M, Amigorena S. Journal Cell Reports Aug 16;40(7):111205 (2022)
  Details

  DOI10.1016/j. Celrep.2022.111205 PMID35977488 PMCIDPMC9396532 DivisionProtein & Nucleic Acid Chemistry
• If it ain't broke, break it: facilitating antigen cross‑presentation AuthorsRodríguez-Silvestre P., Kozik P. Journal Trends in Molecular Medicine 28(4):251-252 (2022)
  Details

  DOI10.1016/j.molmed.2022.02.007 PMID35288004 PMCID  DivisionProtein & Nucleic Acid Chemistry
• To Kill But Not Be Killed: Controlling the Activity of Mammalian Pore-Forming Proteins AuthorsKrawczyk P. A., Laub M., Kozik P. Journal Frontiers in Immunology 11:601405 (2020)
  Details

  DOI10.3389/fimmu.2020.601405 PMID33281828 PMCIDPMC7691655 DivisionProtein & Nucleic Acid Chemistry
• Small Molecule Enhancers of Endosome-to-Cytosol Import Augment Anti-tumor Immunity AuthorsKozik P., Gros M., Itzhak D. N., Joannas L., Heurtebise-Chrétien S., Krawczyk P. A., Rodríguez-Silvestre P., Alloatti A., Magalhaes J. G., Del Nery E., Borner G. H. H., Amigorena S. Journal Cell Reports 32(2):107905. 14 July 2020 (2020)
  Details

  DOI10.1016/j. Celrep.2020.107905 PMID32668257 PMCIDPMC7370168 DivisionProtein & Nucleic Acid Chemistry
• TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination AuthorsBottermann M., Foss S., van Tienen L. M., Vaysburd M., Cruickshank J., O'Connell K., Clark J., Mayes K., Higginson K., Hirst J. C., McAdam M. B., Slodkowicz G., Hutchinson E., Kozik P., Andersen J. T., James L. C. Journal Proceedings of the National Academy of Sciences of the United States of America 115(41):10440-10445. 9 October 2018 (2018)
  Details

  DOI10.1073/pnas.1806314115 PMID30209217 PMCIDPMC6187179 DivisionProtein & Nucleic Acid Chemistry