Published Research
Found 110 results for Evans.
- Tau uptake by human neurons depends on receptor LRP1 and kinase LRRK2 AuthorsEvans L.D., Strano A., Tuck E., Campbell A., Smith J., Hung C., Behr T.S., Ghetti B., Ryskeldi-Falcon B., Karakoc E., Iorio F., Reith A., Bassett A.R., Livesey F.J. Journal The EMBO Journal (2025)
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Engineered receptor capture combined with mass spectrometry enables high-throughput detection and quantitation of SARS-CoV-2 spike protein
AuthorsBate N., Lane D., Evans S.E., Salim F., Allcock N.S., Haigh R., Sale J.E., Jones D.J.L., Brindle N.P.J.
Journal
JACS Au
5(2):747-755 (2025)
Details
DOI10.1021/jacsau.4c00980 PMID40017752 PMCIDPMC11862925 DivisionProtein & Nucleic Acid Chemistry -
Anti-Ebola virus mAb 3A6 protects highly viremic animals from fatal outcome via binding GP(1,2) in a position elevated from the virion membrane
AuthorsHastie K. M., Salie Z. L., Ke Z., Halfmann P. J., Evans DeWald L., McArdle S., Grinyรณ A., Davidson E., Schendel S. L., Hariharan C., Norris M. J., Yu X., Chennareddy C., Xiong X., Heinrich M., Holbrook M. R., Doranz B., Crozier I., Karaoka Y., Branco L. M., Kuhn J. H., Briggs J. A. G., Worwa G., Davis C. W., Ahmed R., Ollmann Saphire E.
Journal
Nature Communications
16(1):1293 (2025)
Details
DOIdoi.org/10.1038/s41467-025-56452-2 PMID39900911 PMCIDPMC11791206 DivisionStructural Studies - How do gepotidacin and zoliflodacin stabilize DNA cleavage complexes with bacterial type IIA topoisomerases? 1. experimental definition of metal binding sites AuthorsMorgan H., Nicholls R. A., Warren A. J., Ward S. E., Evans G., Long F., Murshudov G. N., Duman R., Bax B. D. Journal International Journal of Molecular Sciences 25(21):11688 (2024)
- A redox switch allows binding of Fe(II) and Fe(III) ions in the cyanobacterial iron-binding protein FutA from Prochlorococcus AuthorsBolton R, Machelett MM, Stubbs J, Axford D, Caramello N, Catapano L, Malรฝ M, Rodrigues MJ, Cordery C, Tizzard GJ, MacMillan F, Engilberge S, von Stetten D, Tosha T, Sugimoto H, Worrall JAR, Webb JS, Zubkov M, Coles S, Mathieu E, Steiner RA, Murshudov G, Schrader TE, Orville AM, Royant A, Evans G, Hough MA, Owen RL, Tews I. Journal Proceedings of the National Academy of Sciences of the United States of America 121(12):e2308478121 (2024)
- The CCP4 suite: integrative software for macromolecular crystallography AuthorsAgirre J, Atanasova M, Bagdonas H, Ballard CB, Baslรฉ A, Beilsten-Edmands J, Borges RJ, Brown DG, Burgos-Mรกrmol JJ, Berrisford JM, Bond PS, Caballero I, Catapano L, Chojnowski G, Cook AG, Cowtan KD, Croll TI, Debreczeni Jร, Devenish NE, Dodson EJ, Drevon TR, Emsley P, Evans G, Evans PR, Fando M, Foadi J, Fuentes-Montero L, Garman EF, Gerstel M, Gildea RJ, Hatti K, Hekkelman ML, Heuser P, Hoh SW, Hough MA, Jenkins HT, Jimรฉnez E, Joosten RP, Keegan RM, Keep N, Krissinel EB, Kolenko P, Kovalevskiy O, Lamzin VS, Lawson DM, Lebedev AA, Leslie AGW, Lohkamp B, Long F, Malรฝ M, McCoy AJ, McNicholas SJ, Medina A, Millรกn C, Murray JW, Murshudov GN, Nicholls RA, Noble MEM, Oeffner R, Pannu NS, Parkhurst JM, Pearce N, Pereira J, Perrakis A, Powell HR, Read RJ, Rigden DJ, Rochira W, Sammito M, Sรกnchez Rodrรญguez F, Sheldrick GM, Shelley KL, Simkovic F, Simpkin AJ, Skubak P, Sobolev E, Steiner RA, Stevenson K, Tews I, Thomas JMH, Thorn A, Valls JT, Uski V, Usรณn I, Vagin A, Velankar S, Vollmar M, Walden H, Waterman D, Wilson KS, Winn MD, Winter G, Wojdyr M, Yamashita K. Journal Acta crystallographica. Section D, Structural Biology 79(Pt 6):449-461 (2023)
- The CCP4 suite: integrative software for macromolecular crystallography AuthorsAgirre J, Atanasova M, Bagdonas H, Ballard CB, Baslรฉ A, Beilsten-Edmands J, Borges RJ, Brown DG, Burgos-Mรกrmol JJ, Berrisford JM, Bond PS, Caballero I, Catapano L, Chojnowski G, Cook AG, Cowtan KD, Croll TI, Debreczeni Jร, Devenish NE, Dodson EJ, Drevon TR, Emsley P, Evans G, Evans PR, Fando M, Foadi J, Fuentes-Montero L, Garman EF, Gerstel M, Gildea RJ, Hatti K, Hekkelman ML, Heuser P, Hoh SW, Hough MA, Jenkins HT, Jimรฉnez E, Joosten RP, Keegan RM, Keep N, Krissinel EB, Kolenko P, Kovalevskiy O, Lamzin VS, Lawson DM, Lebedev AA, Leslie AGW, Lohkamp B, Long F, Malรฝ M, McCoy AJ, McNicholas SJ, Medina A, Millรกn C, Murray JW, Murshudov GN, Nicholls RA, Noble MEM, Oeffner R, Pannu NS, Parkhurst JM, Pearce N, Pereira J, Perrakis A, Powell HR, Read RJ, Rigden DJ, Rochira W, Sammito M, Sรกnchez Rodrรญguez F, Sheldrick GM, Shelley KL, Simkovic F, Simpkin AJ, Skubak P, Sobolev E, Steiner RA, Stevenson K, Tews I, Thomas JMH, Thorn A, Valls JT, Uski V, Usรณn I, Vagin A, Velankar S, Vollmar M, Walden H, Waterman D, Wilson KS, Winn MD, Winter G, Wojdyr M, Yamashita K. Journal Acta crystallographica. Section D, Structural Biology 79(Pt 6):449-461 (2023)
- Molecular basis for differential activation of p101 and p84 complexes of PI3Kฮณ by Ras and GPCRs AuthorsRathinaswamy M. K., Jenkins M. L., Duewell B. R., Zhang X., Harris N. J., Evans J. T., Stariha J. T. B., Dalwadi U., Fleming K. D., Ranga-Prasad H., Yip C. K., Williams R. L., Hansen S. D., Burke J. E. Journal Cell Reports 42(3):112172 (2023)
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In vitro evolution predicts emerging SARS-CoV-2 mutations with high affinity for ACE2 and cross-species binding
AuthorsBate N., Savva C.G., Moody P.C.E., Brown E.A., Evans S.E., Ball J.K., Schwabe J.W.R., Sale J.E., Brindle N.P.J.
Journal
Plos Pathogens
18(7):e1010733 (2022)
Details
DOI10.1371/journal.ppat.1010733 PMID35849637 PMCIDPMC9333441 DivisionProtein & Nucleic Acid Chemistry - FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P2-dependent switch AuthorsZaccai N. R., Kadlecova Z., Dickson V. K., Korobchevskaya K., Kamenicky J., Kovtun O., Umasankar P. K., Wrobel A. G., Kaufman J. G. G., Gray S. R., Qu K., Evans P. R., Fritzsche M., Sroubek F., Hรถning S., Briggs J. A. G., Kelly B. T., Owen D. J., Traub L. M. Journal Science Advances 8(17):eabn2018 (2022)
- The predictive power of data-processing statistics AuthorsVollmar M., Parkhurst J. M., Jaques D., Baslรฉ A., Murshudov G. N., Waterman D. G., Evans G. Journal Iucrj 7(Pt 2):342-354. March 2020 (2020)
- Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation AuthorsWrobel A. G., Kadlecova Z., Kamenicky J., Yang J. C., Herrmann T., Kelly B. T., McCoy A. J., Evans P. R., Martin S., Mรผller S., Sroubek F., Neuhaus D., Hรถning S., Owen D. J. Journal Developmental Cell 50(4):494-508.e11. 19 August 2019 (2019)
- A Behavioral Assay for Investigating the Role of Spatial Memory During Instinctive Defense in Mice AuthorsVale R., Evans D., Branco T. Journal Journal of Visualized Experiments : Jove (137):56988 (2018)
- A synaptic threshold mechanism for computing escape decisions AuthorsEvans D. 1., Stempel A. V., Vale R., Ruehle S., Lefler Y., Branco T. Journal Nature 558(7711):590-594. 28 June 2018 (2018)
- CCP4i2: the new graphical user interface to the CCP4 program suite AuthorsPotterton L., Agirre J., Ballard C., Cowtan K., Dodson E., Evans P. R.,Jenkins H. T., Keegan R., Krissinel E., Stevenson K., Lebedev A., McNicholas S. J., Nicholls R. A., Noble M., Pannu N. S., Roth C., Sheldrick G., Skubak P., Turkenburg J., Uski V., von Delft F., Waterman D., Wilson K., Winn M., Wojdyr M. Journal Acta crystallographica. Section D, Structural Biology 74(Pt 2):68-84. 1 February 2018 (2018)
- UV-light-driven prebiotic synthesis of iron-sulfur clusters AuthorsBonfio C., Valer L., Scintilla S., Shah S., Evans D. J., Jin L., Szostak J. W., Sasselov D. D., Sutherland J. D., Mansy S. S. Journal Nature Chemistry 9(12):1229-1234. December 2017 (2017)
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Molecular basis of USP7 inhibition by selective small-molecule inhibitors
AuthorsTurnbull A. P., Ioannidis S., Krajewski W. W., Pinto-Fernandez A., Heride C., Martin A. C. L., Tonkin L. M., Townsend E. C., Buker S. M., Lancia D. R., Caravella J. A., Toms A. V., Charlton T. M., Lahdenranta J., Wilker E., Follows B. C., Evans N. J., Stead L., Alli C., Zarayskiy V. V., Talbot A. C., Buckmelter A. J., Wang M., McKinnon C. L., Saab F., McGouran J. F., Century H., Gersch M., Pittman M. S., Marshall C. G., Raynham T. M., Simcox M., Stewart L. M. D., McLoughlin S. B., Escobedo J. A., Bair K. W., Dinsmore C. J., Hammonds T. R., Kim S., Urbรฉ S., Clague M. J., Kessler B. M., Komander D.
Journal
Nature
550(7677):481-486. 26 October 2017 (2017)
Details
DOI10.1038/nature24451 PMID29045389 PMCIDPMC6029662 DivisionProtein & Nucleic Acid Chemistry - AUSPEX: a graphical tool for X-ray diffraction data analysis AuthorsThorn A., Parkhurst J., Emsley P., Nicholls R. A., Vollmar M., Evans G., Murshudov G. N. Journal Acta Crystallographica. Section D, Structural Biology 73(Pt 9):729-737. September 2017 (2017)
- Background modelling of diffraction data in the presence of ice rings AuthorsParkhurst J. M., Thorn A., Vollmar M., Winter G., Waterman D. G., Fuentes-Montero L., Gildea R. J., Murshudov G. N., Evans G. Journal Iucrj 4(Pt 5):626-638 (2017)
- Rapid Spatial Learning Controls Instinctive Defensive Behavior in Mice AuthorsVale R., Evans D. A., Branco T. Journal Current Biology 27(9):1342-1349. 8 May 2017 (2017)
- Robust background modelling in DIALS AuthorsParkhurst J. M., Winter G., Waterman D. G., Fuentes-Montero L., Gildea R. J., Murshudov G. N., Evans G. Journal Journal of Applied Crystallography 49(Pt 6):1912-1921. 1 December 2016 (2016)
- Structural basis for the binding of tryptophan-based motifs by ฮด-COP AuthorsSuckling R. J., Poon P. P., Travis S. M., Majoul I. V., Hughson F. M., Evans P. R., Duden R., Owen D. J. Journal Proceedings of the National Academy of Sciences of the United States of America 112(46):14242-14247. 17 November (2015)
- Network-mediated encoding of circadian time: the suprachiasmatic nucleus (SCN) from genes to neurons to circuits, and back AuthorsBrancaccio M., Enoki R., Mazuski C. N., Jones J., Evans J. A., Azzi A. Journal Journal of Neuroscience 34(46):15192-15199. 12 November 2014 (2014)
- VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surface AuthorsHesketh G. G., Pรฉrez-Dorado I., Jackson L. P., Wartosch L., Schรคfer I. B., Gray S. R., McCoy A. J., Zeldin O. B., Garman E. F., Harbour M. E., Evans P. R., Seaman M. N., Luzio J. P., Owen D. J. Journal Developmental Cell 29(5):591-606. 9 June 2014 (2014)
- How good are my data and what is the resolution? AuthorsEvans P. R., Murshudov G. N. Journal Acta Crystallographica. Section D, Biological Crystallography 69(Pt 7):1204-1214. 1 July 2013 (2013)
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Bin2 is a membrane sculpting N-BAR protein that influences leucocyte podosomes, motility and phagocytosis
AuthorsSรกnchez-Barrena M. J., Vallis Y., Clatworthy M. R., Doherty G. J., Veprintsev D. B., Evans P. R., McMahon H. T.
Journal
PloS one
7(12):e52401. 20 December 2012 (2012)
Details
DOI10.1371/journal.pone.0052401 PMID23285027 PMCIDPMC3527510 DivisionNeurobiology, Structural Studies, Protein & Nucleic Acid Chemistry -
Molecular basis for recognition of dilysine trafficking motifs by COPI
AuthorsJackson L. P., Lewis M., Kent H. M., Edeling M. A., Evans P. R., Duden R., Owen D. J.
Journal
Developmental Cell
23(6):1255-1262. 11 December 2012 (2012)
Details
DOI10.1016/j. devcel.2012.10.017 PMID23177648 PMCIDPMC3521961 DivisionStructural Studies; Cell Biology - The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation AuthorsSchรคfer I. B., Hesketh G. G., Bright N. A., Gray S. R., Pryor P. R., Evans P. R., Luzio J. P., Owen D. J. Journal Nature Structural & Molecular Biology 19(12):1300-1309. December 2012 (2012)
- Outrunning free radicals in room-temperature macromolecular crystallography AuthorsOwen R. L., Axford D., Nettleship J. E, Owens R. J., Robinson J. I, Morgan A. W., Dorรฉ A. S., Lebon G., Tate C. G., Fry E. E., Ren J., Stuart D. I., Evans G. Journal Acta Crystallographica. Section D, Biological Crystallography 68(Pt 7):810-818. July 2012 (2012)
- Biochemistry. Resolving some old problems in protein crystallography AuthorsEvans P. Journal Science 336(6084):986-987. 25 May 2012 (2012)
- Structural basis of the intracellular sorting of the SNARE VAMP7 by the AP3 adaptor complex AuthorsKent H. M., Evans P. R., Schรคfer I. B., Gray S. R., Sanderson C. M., Luzio J. P., Peden A. A., Owen D. J. Journal Developmental Cell 22(5):979-988. 15 May 2012 (2012)
- An introduction to data reduction: space-group determination, scaling and intensity statistics AuthorsEvans P. R. Journal Acta Crystallographica. Section D D67(4):282-292. 1 April 2011 (2011)
- Overview of the CCP4 suite and current developments AuthorsWinn M. D., Ballard C. C., Cowtan K. D., Dodson E. J., Emsley P., Evans P. R., Keegan R. M., Krissinel E. B., Leslie A. G., McCoy A., McNicholas S. J., Murshudov G. N., Pannu N. S., Potterton E. A., Powell H. R., Read R. J., Vagin A., Wilson K. S. Journal Acta Crystallographica. Section D 67(4):235-242. April 2011 (2011)
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A large-scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complex
AuthorsJackson L. P., Kelly B. T., McCoy A. J., Gaffry T., James L. C., Collins B. M., Hรถning S., Evans P. R., Owen D. J.
Journal
Cell
141(7):1220-1229. 25 June 2010 (2010)
Details
DOI10.1016/j. Cell.2010.05.006 PMID20603002 PMCIDPMC3655264 DivisionProtein & Nucleic Acid Chemistry, Structural Studies - Coordinated regulation of foraging and metabolism in C. elegans by RFamide neuropeptide signaling AuthorsMerav Cohen, Vincenzina Reale, Birgitta Olofsson, Andrew Knights, Peter Evans, Mario de Bono Journal Cell Metabolism 9(4):375-385. 8 April 2009 (2009)
- The Multidimensional Integrated Intelligent Imaging project(MI‑3) AuthorsN. Allinson, T. Anaxagoras, J. Aveyard, C. Arvanitis, R. Bates, A. Blue, S. Bohndiek, J. Cabello, L. Chen, S. Chen, A. Clark, C. Clayton, E. Cook, A. Cossins, J. Crooks, M. El-Gomati, P. M. Evans, W. Faruqi, M. French, J. Gow, T. Greenshaw, T. Greig, N. Guerrini, E. J. Harris, R. Henderson, A. Holland, G. Jeyasundra, D. Karadaglic, A. Konstantinidis, H. X. Liang, K. M. S. Maini, G. McMullen, A. Olivo, V. OโShea, J. Osmond, R. J. Ott, M. Prydderch, L. Qiang, G. Riley, G. Royle, G. Segneri, R Speller, J. R. N. Symonds-Tayler, S. Triger, R. Turchetta, C. Venanzi, K. Wells, X. Zha, H. Zin Journal Nuclear Instruments and Methods in Physics Research A 604: 196โ198 (2009) (2009)
- Molecular Basis for the Sorting of the SNARE VAMP7 into Endocytic Clathrin-Coated Vesicles by the ArfGAP Hrb AuthorsPaul R. Pryor, Lauren Jackson, Sally R. Gray, Melissa A. Edeling, Amanda Thompson, Christopher M. Sanderson, Philip R. Evans, David J. Owen, Paul Luzio Journal Cell 134 (5): 817-827. 5 September 2008 (2008)
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An introduction to molecular replacement
AuthorsPhilip Evans, Airlie McCoy
Journal
Acta Crystallogr Section D Biological Crystallography
64 (Pt 1): 1-10 (2008)
Details
DOI PMID PMCID Division - Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex AuthorsMarc Fiedler, Marรญa Josรฉ Sรกnchez-Barrena, Maxim Nekrasov, Juliusz Mieszczanek, Vladimir Rybin, Jรผrg Mรผller, Phil Evans, Mariann Bienz Journal Molecular Cell 30 (4): 507-18. (2008)
- Common variants near MC4R are associated with fat mass, weight and risk of obesity AuthorsRuth J. F. Loos, Cecilia M. Lindgren, Shengxu Li, Eleanor Wheeler, Jing Hua Zhao, Inga Prokopenko, Michael Inouye, Rachel M. Freathy, Antony P. Attwood, Jacques S Beckmann, Sonja I Berndt, The Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, Sven Bergmann, Amanda J. Bennett, Sheila A. Bingham, Murielle Bochud, Morris Brown, Stรฉphane Cauchi, John M Connell, Cyrus Cooper, George Davey Smith, Ian Day, Christian Dina, Subhajyoti De, Emmanouil T Dermitzakis, Alex S. F. Doney, Katherine S. Elliott, Paul Elliott, David M Evans, I. Sadaf Farooqi, Philippe Froguel, Jilur Ghori, Christopher J. Groves, Rhian Gwilliam, David Hadley, Alistair S. Hall, Andrew T. Hattersley, Johannes Hebebrand, Iris M. Heid, KORA, Blanca Herrera, Anke Hinney, Sarah E. Hunt, Marjo-Riitta Jarvelin, Toby Johnson, Jennifer D. M. Jolley, Fredrik Karpe, Andrew Keniry, Kay-Tee Khaw, Robert N. Luben, Massimo Mangino, Jonathan Marchini, Wendy L. McArdle, Ralph McGinnis, David Meyre, Patricia B. Munroe, Andrew D. Morris, Andrew R. Ness, Matthew J. Neville, Alexandra C. Nica, Ken K. Ong, Stephen O'Rahilly, Katharine R. Owen, Colin N. A. Palmer, Konstantinos Papadakis, Simon Potter, Anneli Pouta, Lu Qi, Nurses' Health Study, Joshua C Randall, Nigel W. Rayner, Susan M. Ring, Manjinder S. Sandhu, Andrรฉ Scherag, Matthew A. Sims, Kijoung Song, Nicole Soranzo, Elizabeth K. Speliotes, Diabetes Genetics Initiative, Holly E. Syddall, Sarah A. Teichmann, Nicholas J. Timpson, Jonathan H. Tobias, Manuela Uda, The SardiNIA Study, Carla I. Ganz Vogel, Chris Wallace, Dawn M. Waterworth, Michael N. Weedon, The Wellcome Trust Case Control Consortium, Cristen J. Willer, FUSION, Vicki L. Wraight, Xin Yuan, Eleftheria Zeggini, Joel N. Hirschhorn, David P. Strachan, Willem H. Ouwehand, Mark J. Caulfield, Nilesh J. Samani, Timothy M. Frayling, Peter Vollenweider, Gerard Waeber, Vincent Mooser, Panos Deloukas, Mark I. McCarthy, Nicholas J. Wareham, Inรชs Barroso, Kevin B. Jacobs, Stephen J. Chanock, Richard B. Hayes, Claudia Lamina, Christian Gieger, Thomas Illig, Thomas Meitinger, H-Erich Wichmann, Peter Kraft, Susan E. Hankinson, David J. Hunter, Frank B. Hu, Helen N. Lyon, Benjamin F. Voight, Martin Ridderstrale, Leif Groop, Paul Scheet, Serena Sanna, Goncalo R. Abecasis, Giuseppe Albai, Ramaiah Nagaraja, David Schlessinger, Anne U. Jackson, Jaakko Tuomilehto, Francis S. Collins, Michael Boehnke, Karen L. Mohlke Journal Nature Genetics 40 (6): 768-775 (2008)
- A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex AuthorsBernard T. Kelly, Airlie J. McCoy, Kira Spรคte, Sharon E. Miller, Philip R. Evans, Stefan Hรถning, David J. Owen Journal Nature 456(7224): 976 (2008) (2008)
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Structure and analysis of FCHo2 F-BAR domain : a dimerizing and membrane recrutiment module that effects membrane curvature
AuthorsWilliam Mike Henne, Helen M. Kent, Marijn G. J. Ford, Balachandra G. Hegde, Oliver Daumke, P. Jonathan G. Butler, Rohit Mittal, Ralf Langen, Philip R. Evans, Harvey T. McMahon
Journal
Structure
15(7): 839-852 (2007) (2007)
Details
DOI PMID PMCID Division - An introduction to stereochemical restraints AuthorsEvans P. R. Journal Acta Crystallogr. Sect. D-Biol. Crystallogr 63(1): 58-61 (2007) (2007)
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Structural analysis of the interaction between the SNARE Tlg1 and Vps51
AuthorsFridmann-Sirkis Y., Kent H. M., Lewis M. J., Evans P. R., Pelham H. R. B.
Journal
Traffic
7(2):182-190. February 2006 (2006 )
Details
DOI10.1111/j.1600-0854.2005.00374.x PMID16420526 PMCID DivisionStructural Studies, Cell Biology - Scaling and assessment of data quality AuthorsEvans P. Journal Acta Crystallographica Section D: Biological Crystallography D62: 72-82. January 2006 (2006)
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NMR analysis of Caenorhabditis elegans FLP-18 neuropeptides: implications for NPR-1 activation
AuthorsAaron T. Dossey, Vincenzina Reale, Heather Chatwin, Cherian Zachariah, Mario de Bono, Peter D. Evans, Arthur S. Edison
Journal
Biochemistry
45: 7586-7597 (2006) (2006)
Details
DOI PMID PMCID Division -
Mechanism of endophilin N-BAR domain-mediated membrane curvature
AuthorsJennifer L. Gallop, Christine C. Jao, Helen M. Kent, P. Jonathan G. Butler, Philip R. Evans, Ralf Langen, Harvey T. McMahon
Journal
EMBO Journal
25: 2898-2910 (2006) (2006)
Details
DOI PMID PMCID Division -
CMOS monolithic active pixel sensors (MAPS): new 'eyes' for science
AuthorsR. Turchetta, P. P. Allport, G. Casse, A. Clark, J. Crooks, A. Evans, A. Fant, A. R. Faruqi, M. J. French, R. Henderson, Q. Morrissey, D. Prior, M. Prydderch, J. J. Velthuis, G. Villani, N. Waltham, B. Willmore, P. Willmore
Journal
Nuclear Instruments & Methods in Physics Research A
560: 139-142 (2006) (2006)
Details
DOI PMID PMCID Division - Non-canonical YXXGphi endocytic motifs: recognition by AP2 and preferential utilization in P2X4 receptors AuthorsRoyle S. J., Qureshi O. S., Bobanovic L. K., Evans P. R., Owen D. J.,Murrell-Lagnado R. D. Journal Journal of Cell Science 118(Pt 14):3073-3080. July 2005 (2005)
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CMOS active pixel sensors for ionising radiation
AuthorsEvans D. A., Allport P. P., Casse G., Faruqi A. R., Gallop B., Henderson R., Prydderch M., Turchetta R., Tyndel M., Velthuis J., Villani G., Waltham N.
Journal
Nuclear Instruments and Methods in Physics Research A
546: 281-285. 1 July 2005 (2005)
Details
DOI PMID PMCID Division -
Direct single electron detection with a CMOS detector for electron microscopy
AuthorsA. R. Faruqi, R. Henderson, M. Pryddetch, P. Allport, A. Evans
Journal
Nuclear Instruments and Methods in Physics Research A
546 : 170-175 (2005) (2005)
Details
DOI PMID PMCID Division - Two distinct interaction motifs in amphiphysin bind two independent sites on the clathrin terminal domain beta‑propeller AuthorsAdriana E. Miele, Peter J. Watson, Philip R. Evans, Linton M. Traub, David J. Owen Journal Nature Structural & Molecular Biology 11(3):242-248. March 2004 (2004)
- BAR domains as sensors of membrane curvature: the amphiphysin BAR structure AuthorsBrian J. Peter, Helen M. Kent, Ian G. Mills, Yvonne Vallis, P. Jonathan G. Butler, Philip R. Evans, Harvey T. McMahon Journal Science 303(5657):495-499 (2004) (2004)
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Adaptors for clathrin coats: structure and function
AuthorsDavid J. Owen, Brett M. Collins, Philip R. Evans
Journal
Annu. Rev. Cell Dev. Biol.
20: 153-191 (2004) (2004)
Details
DOI PMID PMCID Division - Inhibition of Caenorhabditis elegans social feeding by FMRFamide-related peptide activation of NPR-1 AuthorsRogers C., Reale V., Kim K., Chatwin H., Li C., Evans P., de Bono M. Journal Nature Neuroscience 6(11):1178-1185. November 2003 (2003)
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EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking
AuthorsMills I. G., Praefcke G. J. K., Vallis Y., Peter B. J., Olesen L. E., Gallop J. L., Butler P. J. G., Evans P. R.,McMahon H. T.
Journal
Journal of Cell Biology
160(2):213-222. 21 January 2003 (2003)
Details
DOI10.1083/jcb.200208023 PMID12538641 PMCIDPMC2172650 DivisionNeurobiology, Structural Studies -
Phasing the AP2 core complex with Xe, Hg and Se
AuthorsPhilip Evans
Journal
Acta Crystallographica Section D: Biological Crystallography
D59: 2039-2043 (2003) (2003)
Details
DOI PMID PMCID Division -
A conformational switch between transcriptional repression and replication initiation in the RepA dimerization domain
AuthorsRafael Giraldo, Carlos Fernandez-Tornero, Philip R. Evans, Ramon Diaz-Orejas, Antonio Romero
Journal
Nature Structural Biology
10: 565-571 (2003) (2003)
Details
DOI PMID PMCID Division - Endocytosis and vesicle trafficking AuthorsEvans P. R., Owen D. J. Journal Current Opinion in Structural Biology 12(6):814-821. 1 December 2002 (2002)
- Curvature of clathrin-coated pits driven by epsin AuthorsFord M. G. J., Mills I. G., Peter B. J., Vallis Y., Praefcke G. J. K., Evans P. R., McMahon H. T. Journal Nature 419(6905):361-366. 26 September 2002 (2002)
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Gamma-Adaptin appendage domain: structure and binding site for Eps15 and gamma‑synergin
AuthorsKent H. M., McMahon H. T., Evans P. R., Benmerah A., Owen D. J.
Journal
Structure
10(8):1139-1148. August 2002 (2002)
Details
DOI10.1016/s0969-2126(02)00801-8 PMID12176391 PMCID DivisionNeurobiology, Structural Studies - Molecular architecture and functional model of the endocytic AP2 complex AuthorsCollins B. M., McCoy A. J., Kent H. M., Evans P. R., Owen D. J. Journal Cell 109(4):523-535. 17 May 2002 (2002)
- The structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12 AuthorsLove J. D., Gooch J. T., Benko S., Li C., Nagy L., Chatterjee V. K, Evans R. M., Schwabe J. W. R. Journal Journal of Biological Chemistry 277(13):11385-11391. 29 March 2002 (2002)
- The structure of the ultraspiracle ligand-binding domain reveals a nuclear receptor locked in an inactive conformation AuthorsClayton G. M., Peak-Chew S. Y., Evans R. M., Schwabe J. W. R. Journal Proceedings of the National Academy of Sciences 98(4):1549-1554. 13 February 2001 (2001)
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Simultaneous binding of Ptdlns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes
AuthorsFord M. G. J., Pearse B. M. F., Higgins M. K., Vallis Y., Owen D. J., Gibson A., Hopkins C. R., Evans P. R., McMahon H. T.
Journal
Science
291(5506):1051-1055. 9 February 2001 (2001)
Details
DOI10.1126/science.291.5506.1051 PMID11161218 PMCID DivisionStructural Studies, Neurobiology - The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase Gcn5p AuthorsOwen D. J., Ornaghi P., Yang J-C., Lowe N., Evans P. R., Ballario P., Neuhaus D., Filetici P., Travers A. A. Journal EMBO Journal 19(22):6141-6149. 15 November 2000 (2000)
- The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase Gcn5p AuthorsOwen D. J., Ornaghi P., Yang J-C., Lowe N., Evans P. R., Ballario P., Neuhaus D., Filetici P., Travers A. A. Journal EMBO Journal 19(22):6141-6149 (2000) (2000)
- The structure and function of the beta2-adaptin appendage domain AuthorsOwen D. J., Vallis Y., Pearse B. M. F., McMahon H. T., Evans P. R. Journal EMBO Journal 19(16):4216-4227. 15 August 2000 (2000)
- The structure and function of the beta2-adaptin appendage domain AuthorsOwen D. J., Vallis Y., Pearse B. M. F., McMahon H. T., Evans P. R. Journal EMBO Journal 19(16):4216-4227 (2000) (2000)
- Distribution of the neurotensin receptor NTS1 in the rat CNS studied using an amino-terminal directed antibody AuthorsFassio A., Evans G., Grisshammer R., Bolam J. P., Mimmack M., Emson P. C. Journal Neuropharmacology 39(8):1430-1442 (2000) (2000)
- Mechanism of corepressor binding and release from nuclear hormone receptors AuthorsNagy L., Kao H-Y., Love J. D., Li C., Banayo E., Gooch J. T., Krishna V., Chatterjee K., Evans R. M., Schwabe J. W. R. Journal Genes & Development 13(24):3209-3216. 15 December 1999 (1999)
- Crystal structure of substrate complexes of methylmalonyl-CoA Mutase AuthorsMancia F., Smith G. A., Evans P. R. Journal Biochemistry 38(25):7999-8005 (1999) (1999)
- A structural explanation for the binding of multiple ligands by the alpha - adaptin appendage domain AuthorsOwen D. J., Vallis Y., Noble M. E. M., Hunter J. B., Dafforn T. R., Evans P. R., McMahon H. T. Journal Cell 97(6):805-815 (1999) (1999)
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Importance of the pleckstrin homology domain of dynamin in clathrin-mediated endocytosis
AuthorsVallis Y., Wigge P., Marks B., Evans P. R., McMahon H. T.
Journal
Current Biology
9(5):257-260 (1999) (1999)
Details
DOI10.1016/s0960-9822(99)80114-6 PMID10074456 PMCID DivisionNeurobiology, Structural Studies - Importance of the pleckstrin homology domain of dynamin in clathrin-mediated endocytosis AuthorsVallis Y., Wigge P., Marks B., Evans P. R., McMahon H. T. Journal Current Biology 9(5):257-260 (1999) (1999)
- A structural explanation for the recognition of tyrosine-based endocytotic signals AuthorsDavid J. Owen, Philip R. Evans Journal Science 282(5392):1327-1332. 13 November 1998 (1998)
- Crystal structure of the spliceosomal U2B''-U2A' protein complex bound to a fragment of U2 small nuclear RNA AuthorsPrice S. R., Evans P. R., Nagai K. Journal Nature 394(6694):645-650. 13 August 1998 (1998)
- Conformational changes on substrate binding to methylmalonyl coA mutase and new insights into the free radical mechanism AuthorsMancia F., Evans P. R. Journal Structure 6(6):711-720. 15 June 1998 (1998)
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Crystal structure of the amphiphysin-2 SH3 domain and its role in the prevention of dynamin ring formation
AuthorsD. J. Owen, P. Wigge, Y. Vallis, J. D. A. Moore, P. R. Evans, H. T. McMahon
Journal
EMBO Journal
17: 5273-5285 (1998) (1998)
Details
DOI PMID PMCID Division - Following cell fate in the living mouse embryo AuthorsZernicka-Goetz M., Pines J., McLean Hunter S., Dixon J. P., Siemering K. R., Haseloff J., Evans M. J. Journal Development 124(6):1133-1137. March 1997 (1997)
- An indelible lineage marker for Xenopus using a mutated green fluorescent protein AuthorsZernicka-Goetz M., Pines J., Ryan K., Siemering K. R., Haseloff J., Evans M. J., Gurdon J. B. Journal Development 122(12):3719-3724. December 1996 (1996)
- How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 angstrom resolution AuthorsFilippo Mancia, Nicholas H. Keep, Atsushi Nakagawa, Peter F. Leadlay, Sean McSweeney, Bjarne Rasmussen, Peter Bosecke, Olivier Diat, Philip R. Evans Journal Structure 4(3):339-350. March 1996 (1996)
- The RNP domain: a sequence-specific RNA-binding domain involved in processing and transport of RNA AuthorsNagai K., Oubridge C., Ito N., Avis J., Evans P. Journal Trends in Biochemical Sciences 20(6):235-240. June 1995 (1995)
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The Hox11 gene is essential for cell survival during spleen development
AuthorsT. N. Dear, W. H. Colledge, M. B. L. Carlton, I. Lavenir, T. Larson, A. J. H. Smith, A. J. Warren, M. J. Evans, M. V. Sofroniew, T. H. Rabbitts
Journal
Development
121: 2909-2915 (1995) (1995)
Details
DOI PMID PMCID Division - Crystal structure at 1.92 angstrom resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin AuthorsOubridge C., Ito N., Evans P. R., Teo C. H., Nagai K. Journal Nature 372(6505):432-438. 1 December 1994 (1994)
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The oncogenic cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
AuthorsAlan J. Warren, William H. Colledge, Mark B. L. Carlton, Martin J. Evans, Andrew J. H. Smith, Terence H. Rabbitts
Journal
Cell
78: 45-57 (1994) (1994)
Details
DOI PMID PMCID Division - Structural studies of proteins in solution using proton nuclear magnetic resonance AuthorsNeuhaus D., Evans P. A. Journal Methods in Molecular Biology, Vol. 17: Spectroscopic Methods and Analyses: NMR, Mass Spectrometry, and Metalloprotein Techniques. Edited by C. Jones, B. Mulloy and A. H. Thomas 17:15-67 (1993) (1993)
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Site-directed mutagenesis identifies catalytic residues in the active site of Escherichia coli phosphofructokinase
AuthorsStuart A. Berger, Philip R. Evans
Journal
Biochemistry
31: 9237-9242 (1992) (1992)
Details
DOI PMID PMCID Division -
The mechanism of Z alpha1-antitrypsin accumulation in the liver
AuthorsDavid A. Lomas, Dyfed LI. Evans, John T. Finch, Robin W. Carrell
Journal
Nature
357: 605-607 (1992) (1992)
Details
DOI PMID PMCID Division -
Activity and allosteric regulation in bacterial phosphofructokinase
AuthorsEvans P. R.
Journal
Proceedings of The Robert A. Welch Foundation Conference on Chemical Research. XXXVI. Regulation of proteins by Ligands
pp.39-54 (1992) (1992)
Details
DOI PMID PMCID Division - Structural aspects of allostery AuthorsEvans P. R. Journal Current Opinion in Structural Biology 1(5): 773-779 (1991) (1991)
- Steady-state fluorescence of Escherichia coli phosphofructokinase reveals a regulatory role for ATP AuthorsStuart A. Berger, Philip R. Evans Journal Biochemistry 30(34): 8477-8480 (1991 ) (1991)
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Designing an allosterically locked phosphofructokinase
AuthorsCraig E. Kundrot, Philip R. Evans
Journal
Biochemistry
30: 1478-1484 (1991)
(1991)
Details
DOI PMID PMCID Division - Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A AuthorsNagai K., Oubridge C., Jessen T. H., Li J., Evans P R. Journal Nature 348(6301):515-520 (1990) (1990)
- Active-site mutants altering the cooperativity of E. coli phosphofructokinase AuthorsBerger S. A., Evans P. R. Journal Nature 343(6258):575-576. 8 February 1990 (1990)
- Structural basis of the allosteric behaviour of phosphofructokinase AuthorsSchirmer T., Evans P. R. Journal Nature 343(6254):140-145. 11 January 1990 (1990)
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Biotinyl and phosphotyrosinyl phosphoramidite derivatives useful in the incorporation of multiple reporter groups on synthetic oligonucleotides
AuthorsKonrad Misiura, Ian Durrant, Michael R. Evans, Michael J. Gait
Journal
Nucleic Acids Research
18: 4345-4354 (1990)
(1990)
Details
DOI PMID PMCID Division -
Crystal structure of unliganded phosphofructokinase from Escherichia coli
AuthorsWojciech R. Rypniewski, Philip R. Evans
Journal
Journal of Molecular Biology
207: 805-821 (1989) (1989)
Details
DOI PMID PMCID Division -
Crystallization and preliminary diffraction data for adenosylcobalamin-dependent methlmalonyl-CoA mutase from Propionibacterium shermanii
AuthorsNeil Marsh, Peter F. Leadlay, Philip R. Evans
Journal
Journal of Molecular Biology
200: 421-422 (1988) (1988)
Details
DOI PMID PMCID Division -
Crystal structure of the complex of phosphofructokinase from Escherichia coli with its reaction products
AuthorsYasuo Shirakihara, Philip R. Evans
Journal
Journal of Molecular Biology
204: 973-994 (1988) (1988)
Details
DOI PMID PMCID Division -
Mutations in the active site of Escherichia coli
phosphofructokinase
AuthorsHomme W. Hellinga, Philip R. Evans
Journal
Nature
327: 437-439 (1987) (1987)
Details
DOI PMID PMCID Division -
Site-directed mutagenesis in the effector site of
Escherichia coli phosphofructokinase
AuthorsFrankie Tat-Kwong Lau, Alan R. Fersht, Homme W. Hellinga, Philip R. Evans
Journal
Biochemistry
26: 4142-4148 (1987) (1987)
Details
DOI PMID PMCID Division -
The mechanism of action of interferon-alpha (IFN-alpha) in hairy-cell leukaemia; Hu-IFN-alpha2 receptor expression by hairy cells and other normal and leukaemic cell types
AuthorsRoya Dadmarz, Tom Evans, David Secher, Nicholas Marshall, John Cawley
Journal
Leukemia Research
10: 1279-1285 (1986) (1986)
Details
DOI PMID PMCID Division -
Crystallographic structure of aIIosterically inhibited phosphofructokinase at 7Angstrom resolution
AuthorsP. R. Evans, G. W. Farrants, M. C. Lawrence
Journal
Journal of Molecular Biology
191: 713-720 (1986) (1986)
Details
DOI PMID PMCID Division -
Nucleotide sequence and high-level expression of the major Escherichia coli phosphofructokinase
AuthorsHomme W. Hellinga, Philip R. Evans
Journal
European Journal of Biochemistry
149: 363-373 (1985) (1985)
Details
DOI PMID PMCID Division -
Relative absorption correction for rotation film data
AuthorsC. E. Schutt, P. R. Evans
Journal
Acta Cryst.
A41: 568-570 (1985) (1985)
Details
DOI PMID PMCID Division - Clinical testing of gliadin fractions in coeliac patients AuthorsCiclitira P. J., Evans D. J., Fagg N. L. K., Lennox E. S., Dowling R. H. Journal Clinical Science 66(3):357-364. 1 March 1984 (1984)
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Kinetics of internalisation and degradation of
surface-bound interferon in human lymphoblastoid cells
AuthorsTom Evans, David Secher
Journal
EMBO Journal
3: 2975-2978 (1984) (1984)
Details
DOI PMID PMCID Division - Phosphofructokinase: structure and control AuthorsEvans P. R., Farrants G. W., Hudson P. J. Journal Phil. Trans. R. Soc. Lond. B 293(1063):53-62 (1981) (1981)
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Structure and control of phosphofructokinase from Bacillus stearothermophilus
AuthorsP. R. Evans, P. J. Hudson
Journal
Nature
279: 500-504 (1979) (1979)
Details
DOI PMID PMCID Division