Articles

Showing all articles.

• Taking science from the bench to policy change
  Authors Tafilaku, Jonida Source MRC Insight blog 17 July 2019 Year 2019
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  Subject Jonida Tafilaku, PhD student at the LMB, spoke to the MRC about her time as an intern at the Parliamentary Office of Science and Technology. Keywords Jonida Tafilaku, Parliamentary Office of Science and Technology (POST); UKRI Policy Internships Scheme; producing reports; climate change; mosquitoes; policy-making; science writing; politicians; PhD student
• The advent and rise of monoclonal antibodies
  Authors Rajewsky, Klaus Source Nature 7 November 2019 Year 2019
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  Subject Opinion piece recounts the dramatic impact of the pivotal 1975 paper by Köhler–Milstein on biomedical and, specifically, immunological research, which was propelled by scientific developments that occurred around the time the paper appeared Keywords Georges Köhler; César Milstein; monoclonal antibodies; immunized mouse; antigen; hybridomas; therapeutic; somatic hypermutation; gene-expression; ‘barcoded’; ligand‑binding
• The Alliance Awards the Gregory Paul Lenardo Basic Science Award to Scholar Nick Ader
  Authors International Biomedical Research Alliance Source International Biomedical Research Alliance 24 September 2019 Year 2019
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  Subject The award endowed by NIH Oxford-Cambridge Scholars Program Co-Founder, Michael Lenardo, was given to Nicholas in recognition of his PhD work conducted in Wanda Kukulski’s lab Keywords Nick Ader; award; Michael Lenardo; Wanda Kukulski; alumni; Gregory Paul Lenardo; Alliance
• Top Ten Neuroscience Breakthroughs of 2018
  Authors Micro Control Instruments Source Micro Control Instruments 7 January 2019 Year 2019
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  Subject A list of the top ten neuroscience breakthroughs of 2018 includes work by the LMB’s Sjors Scheres and Michel Goedert on tau protein folds and by Greg Jefferis on imaging the fly brain, as well as alumnus Jonny Kohl for his work mapping neural circuitry associated with parenting. Keywords Tau protein; Alzheimer’s disease; Sjors Scheres; Michel Goedert; frontotemporal dementia; Cryo-electron microscopy; misfolded; Pick’s disease; fly brain imaged; nanoscale resolution; 3D volume; synaptic level; Johnny Kohl; alumni; galanin-expressing neurons; optogenetic tools; parental circuitry
• Traumatic Tau: Filaments from CTE Share Distinct Structure
  Authors ALZFORUM Source ALZFORUM 21 March 2019 Year 2019
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  Subject Researchers in Michel Goedert’s and Sjors Scheres’ groups have revealed the structure of tau filaments from the head injury-associated neurodegenerative disease chronic traumatic encephalopathy Keywords Michel Goedert; Sjors Scheres; chronic traumatic encephalopathy (CTE); Tau filaments; Alzheimer’s disease; “punch-drunk syndrome”; neurodegenerative; Pick’s disease; cryo-EM; Benjamin Falcon; boxers; American Football player
• Tributes following the death of the LMB’s Kiyoshi Nagai at 70
  Authors Paul Brackley Source Cambridge Independent 9th October 2019 Year 2019
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  Subject Nagai’s legacy. The scientist who played a leading role in what is described as one of the greatest achievements in modern molecular biology Keywords E. Coli; Richard Henderson; RNA; DNA; Spliceome;
• Unravelling protein structures found in the brains of dementia patients
  Authors Brackley, Paul Source Cambridge Independent 3-9 April 2019 Year 2019
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  Subject Dr Benjamin Falcon has won a Rising Star Award from Alzheimer’s Research UK for his work, which could aid the diagnosis and eventually the treatment of diseases including Alzheimer’s and CTE Keywords Ben Falcon; Alzheimer’s Research; tau proteins; Michel Goedert; Pick’s disease; chronic traumatic encephalopathy (CTE); neurodegenerative; cryo-EM; dementia; Rising Star Award; filaments; boxers American football player
• Unravelling protein structures found in the brains of dementia patients
  Authors Paul Brackley Source Cambridge Independent April 3rd 2019 Year 2019
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  Subject Ben Falcon has won a rising start award from Alzheimer’s Research UK for his work, which could aid the diagnosis and eventually the treatment of diseases including Alzeimer’s and CTE. Keywords Ben Falcon; Rising start award; CTE.
• Weird synthetic proteins could let us build new kinds of life
  Authors Highfield, Roger Source Wired 26 August 2019 Year 2019
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  Subject Article on Jason Chin and his team’s work focusing on “turbocharging the ribosome”. Jason explains the process behind evolving new ribosomes and it marks a revolution in our ability to evolve, manufacture and discover polymer sequences Keywords Jason Chin; amino acids; proteins; canonical 20; synthesise polymers; ribosome; RNA; 3D proteins; beneficial mutations; ‘orthogonal ribosome’; turbocharging; genetic code; codons; gene therapy; chemical units
• What is a brain? Cerebral organoids are becoming more brainlike
  Authors The Economist Source The Economist 29 August 2019 Year 2019
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  Subject The Economist draws on the evolution of the first cerebral organoids in Madeline Lancaster’s lab in 2013 to today’s research on electrical impulses from these mini brains Keywords Madeline Lancaster; “cerebral organoid’; pluripotent human stem cells; embryonic; Alysson Muotri; neurons; electrical pulsing; synchronised