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• Sjors Scheres, of MRC LMB, earns Royal Society Leeuwenhoek Medal for innovations in cryo-EM image analysis
  Authors Brackley, Paul Source Cambridge Independent 19 August 2021 Year 2021
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  Subject Sjors Scheres,group leader in the Structural Studies division, has won the Royal Society’s Leeuwenhoek Medal, for his innovations in the field of electron cryo‑microscopy. Keywords Sjors Scheres; Leeuwenhoek Medal; cryo-EM; RELION; Alzheimer’s; Michel Goedert; tau filaments; amyloids; award; atomic level
• Spread of Delta SARS-CoV-2 variant driven by combination of immune escape and increased infectivity
  Authors University of Cambridge Source University of Cambridge 6 September 2021 Year 2021
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  Subject Guido Papa and Anna Albecka-Moreau in the James lab contribute to University of Cambridge study, finding that Delta variant spike protein induces higher cell-cell fusion and is less sensitive to inhibition by neutralising antibodies present in vaccinated individuals than the original SARS-CoV-2 strain Keywords SARS-CoV-2; Delta variant; dominant; evade neuralising antibodies; mutations; transmissible; vaccines; coronavirus; Alpha; COVID-19; Oxford/AstraZeneca; Pfizer; ‘pseudotyped virus’; organoids; Guido Papa; Anna Albecka-Moreau; ACE2; Partha Rakshit; Anurag Agrawal; spike proteins
• STFC technology drives more efficient cryoEM imaging
  Authors UK Research and Innovation Source UKRI News 8 July 2021 Year 2021
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  Subject A new Quantum C100 detector, optimised for 100 keV low-energy cryo-EM, has been developed by STFC in partnership with the Rosalind Franklin Institute and LMB Keywords Electron cryo-microscopy (cryoEM); Science and Technology Facilities (STFC); Rosalind Franklin Institute; Quantum Detectors; low energy; Richard Henderson; Chris Russo; collaboration; democratisation of cryoEM technology
• Strength of the powerlifting community helps put Camille Holland on the path to world championships
  Authors Taylor, Mark Source Cambridge Independent, 3 August 2021 Year 2021
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  Subject Camille Holland, a member of the LMB’s Human Resources team, talks to the Cambridge Independent about powerlifting, and the support of the powerlifting community with her continuing training ahead of the World Powerlifting Championships in October Keywords Camille Holland; World Powerlifting Championships; Great Britian; lockdown; Iron Ladies; community; weight lifting; gym
• The body clock, our heartbeat and the impact on our health
  Authors Brackley, Paul Source Cambridge Independent 27 October 2021 Year 2021
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  Subject LMB and AstraZeneca research that suggests why shift workers are prone to heart problems and the elderly are more likely to have a cardiac event in the morning Keywords Heart rate; circadian rhythms; ‘body clock’; John O’Neill; Peter Newham; AstraZeneca; heart cells; shift workers; arrhythmias; ion; cardiac sodium; potassium; Bluesky collaboration; chrono-pharmacology; cardiac event
• The institute mourns the loss of Kenneth C. Holmes
  Authors Max Planck Institute Source Max Planck Institute 8 November 2021 Year 2021
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  Subject Ken Holmes, LMB alumnus and friend, has died at the age of 86. He was a PhD student with Rosalind Franklin at Birkbeck College, London, and moved to the LMB alongside Aaron Klug in 1961 Keywords Ken Holmes; J. D. Bernal; Roselind Franklin; tobacco mosaic virus (TMV); X-ray diffraction; Hugh Huxley; myosin filaments; muscle; APT; Aaron Klug; synchrotron; obituary; alumni
• The life and work of Robert (Bob) C. Sheppard
  Authors Wade, John D., Jones J. H. Source Journal of Peptide Science 24 August 2021 Year 2021
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  Subject A look at the life and work of Robert Charles Sheppard (1932-2019) known to his friends as Bob. He was a leading pioneer of solid phase peptide synthesis and made the most significant and fundamental European contribution to the art of peptide synthesis since Emil Fischer. Keywords Robert (Bob) Sheppard; alumni; Max Perutz; peptide; protein chemistry; Doug Dyckes; Eric Atherton; solid phase peptide synthesis (SPPS); Tom Creighton; polyamide; Derek Clive; Reza Arshady; David East; Mike Gait; Fred Sanger; George Brownlee; Chris Logan; amino acids; Queen's Award for Technological Achievement; Fmoc; oligonucleotide; John Wade
• The Microscopists podcast with Richard Henderson
  Authors O’Toole, Peter Source BiteSize Bio, The Microscopists 10 June 2021 Year 2021
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  Subject Richard Henderson is a guest on The Microscopists podcast from Bitesize Bio. Here he chats with Peter O’Toole about a range of topics including; the fundamental importance of understanding protein structures, what attracted him to biophysics and his motorbike adventures in Scotland Keywords Richard Henderson; podcast; electron microscopy; Joachim Frank; Jacques Dubochet; Fred Sanger; Max Perutz; Malcolm Weir; Heptares; vaccines; coronavirus; old clocks; radio; fixing; Brian Hartley; Paul Emsley; Twitter; Facebook; Breaking Bad; Hitchcock; electromicroscopy; Ada Yonath; Michael Rossmann; Cryo EM
• The neurobiologist who grew ‘mini-brain’ tissues in a dish
  Authors Goodyear, Charis Source University of Cambridge 22 September 2021 Year 2021
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  Subject Cell Biology Group Leader Madeline Lancaster discusses how her ‘failed’ attempt to grow neural stem cells led to the development of brain organoids – miniature brain tissues – which she uses in her research today to better understand the human brain. Keywords Madeline Lancaster; ‘mini-brain’; Petri dish; floating balls; Matrigel; self-organise; organoids; stem cell; great apes; gorilla; chimpanzee; neurons; neurodegeneration; cognitive capabilities
• Thomas Arthur Steitz. 23 August 1940-9 October 2018
  Authors Ramakrishnan Venki.; Henderson, Richard Source Biographical Memoirs of Fellows of The Royal Society 1 December 2021 Year 2021
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  Subject Thomas Steitz Royal Society Biographical Memoir written by Venki Ramakrishnan and Richard Henderson Keywords Thomas A. Steitz; macromolecules; a-chymotrypsin; David Blow; Max Perutz; crystallography; Fourier maps; Richard Henderson; N-formy-ltryptophan; Brian Matthews; dioxan; hydrolysis; Brian Hartley; trypsin; Joan Steitz; Francis Crick; ATCase; hydrophobic; Hans Neurath; Ross Jakes; Jens Birktoft; alumni; 50S structure; tRNA; ribosome