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Articles

The LMB Archive collates scanned/digitised newspaper, magazine and web articles that relate to the activities of the LMB. This database lists the articles that have been catalogued so far.

These articles are the copyright of the originating organisation. They may be accessed for reference-only purposes at the LMB. Alternatively, you can contact the copyright holder for direct requests to access or use their articles.

For recent news stories from the LMB, please see our Latest News page.

Please contact the Archive if you have any questions about this database.

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  • First cells reprogrammed to make synthetic polymers – and virus-resistant drug manufacturers
    Authors PhysOrg Source PhysOrg 3 June 2021 Year 2021
    Details Subject A study led by the LMB has developed the first cells that can construct artificial polymers from building blocks that are not found in nature, by following instructions the researchers encoded in their genes. Keywords synthetic genome; bacteria; viruses; polymer; amino acids; Escherichia coli (E.coli); Jason Chin; codons; antibiotics; tRNAs; macrocycles; drugs; genetic code; sequence; monomers
  • First detailed images captured of molecule associated with ALS
    Authors Cambridge Network Source Cambridge Network 10 December 2021 Year 2021
    Details Subject The structure of the molecule associated with ALS has been determined for the first time by Ben Ryskeldi-Falcon’s Group Keywords Amyotrophic lateral sclerosis (ALS); TDP-43; cryo-EM; Benjamin Ryskeldi-Falcon; neurodegenerative disease; clumping; aggregates
  • First synthetic cells that could make drugs created at LMB
    Authors Brackley, Paul Source Cambridge Independent 9-15 June 2021 Year 2021
    Details Subject Scientists at the LMB have programmed bacteria to act like renewable and programmable factories, with the potential to create antibodies or biodegradable plastics Keywords Jason Chin; antibiotics; biodegradable plastics; synthetic genome; polymers; building blocks; monomers; bacteria; viruses; E. coli; codon; amino acids; macrocycles; genetic code; Daniel de la Torre; Wesley Robertson; Louise Funke; Julius Fredens
  • Genetic code breakthrough opens door to advanced materials
    Authors Cookson, Clive Source Financial Times 4 June 2021 Year 2021
    Details Subject A project led by Jason Chin has re-engineered the genetic code of microbes to create a synthetic cell with capabilities unlike anything in nature, opening up the possibility of new materials for everything from plastics to antibiotics. Keywords Jason Chin; genetic code; microbes; synthetic cell; antibiotics; amino acids; E. coli; “codons”; monomers; “non-natural building blocks”; viruses; Syn61 bacterium; biodegradable plastics
  • Global bottleneck holding up discovery using cryo-EM is solved by MRC Laboratory of Molecular Biology in Cambridge
    Authors Brackley, Paul Source Cambridge Independent 26 November 2021 Year 2021
    Details Subject Chris Russo and PhD student, Katerina Naydenova, are interviewed by the Cambridge Independent on their exciting new optimisation method for making cryo-EM grids Keywords Chris Russo; Katerina Naydenova; cryo-electron microscopy; grids; all-gold; HexAuFoil; semiconductor processing; MEMS technology; microlithography; bottleneck; Quantifoil; SPT Labtech; Richard Henderson
  • In memoriam: Jefferson Foote
    Authors Ward, Sally E., Jones, Peter, Buss, Tim, Rada, Cristina, Winter, Gregory, Willson, Richard Source MABS 12 January 2021 Year 2021
    Details Subject In a scientific career that spanned over three decades, Dr. Jeff Foote made seminal contributions to antibody humanization and the biophysical aspects of antibody recognition. In this Perspective, we discuss his life and work. Keywords Jefferson (Jeff) Foote; immunochemistry; antibody humanization; Greg Winter; Cesar Milstein; fluorometers; Macintosh (“Mac”); antibody engineering; CDR grafting; therapeutic; Campath-1; “conformational isomerism”; Perspective; Arrowsmith Technologies
  • Lab grows small brains to answer the big question
    Authors Blakely, Rhys Source The Times 25 March 2021 Year 2021
    Details Subject Madeline Lancaster’s group have shed light on the why humans develop much bigger brains than apes, an important step in the scientific understanding of neural development. Keywords Madeline Lancaster; “mini-brains”; human; chimpanzee; stem cell; ZEB2; organoids; neurons; progenitor cells; apes
  • LifeArc’s technology transfer team supports MRC researchers in making cryo-electron microscopy even sharper
    Authors LifeArc Source LifeArc 3 November 2021 Year 2021
    Details Subject LifeArc filed applications for a patent and trademark for the new all-gold grids developed by Chris Russo’s group. Helping to bring them to the marked as soon as possible. Keywords cryo-EM; gold grids; HexAuFoil; Chris Russo; LifeArc; ‘cryoEvap’; gold film
  • LMB reveals fresh insight into neurodegenerative disease
    Authors Brackley, Paul Source Cambridge Independent 6 October 2021 Year 2021
    Details Subject New insight into a range of neurodegenerative diseases has been achieved by LMB using cryo-electron microscopy Keywords Michel Goedert; Sjors Scheres; tauopathies; cryo-electron microscopy (cryo-EM); tau filaments; Alzheimer’s; neurodegeneration; brain tissues
  • LMB solves structure of ALS molecule to aid hunt for drugs
    Authors Brackley, Paul Source Cambridge Independent 23 December 2021 Year 2021
    Details Subject The structure of the molecule associated with ALS has been determined for the first time by Ben Ryskeldi-Falcon’s Group Keywords Amyotrophic lateral sclerosis (ALS); Motor neurone disease; Clumped TDP-43; Alzheimer’s disease; Parkinson’s; Benjamin Ryskeldi-Falcon; Diana Arseni; Alexey Murzin; cryo-EM; amyloid filaments; tau; alpha-synuclein; FTD; neurodegenerative disease; ‘aggregates’

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